Search Antibody, Protein, and ELISA Kit Solutions

Exoc4 Antibody (OAED00236)

50 ug
$230.00
In Stock
Request Bulk Order Quote

Gene Symbol:
Exoc4
NCBI Gene Id:
116654
Official Gene Full Name:
Exocyst complex component 4
Protein Name:
Exocyst complex component 4
Swissprot Id:
Q62824
Protein Accession #:
NP_446327.1
Nucleotide Accession #:
NM_053875.1
Alias Symbols:
rSec8 MAb; Exocyst complex component 4; Sec8; Sec8l1
Replacement Item:
This antibody may replace item sc-100734 from Santa Cruz Biotechnology.
Description of Target:
rSec6 and rSec8 are rat homologs of the yeast Sec6 and Sec8 proteins that are essential for protein transport between the Golgi apparatus and the plasma membrane. In yeast, Sec8 is part of a 19.5S complex that includes Sec6 and Sec15, that also associate with the ras-like GTP binding protein Sec4. An analogous 17S complex in rat brain was found to contain rSec6 and rSec8, along with eight proteins with a combined molecular weight of 743 kDa. The membrane-associated rSec6/8 complex co-immunoprecipitates with syntaxin, providing evidence that this complex is involved in synaptic vesicle docking and fusion at the presynaptic terminal.
Molecular Weight:
~110 kDa
Host:
Mouse
Clonality:
Monoclonal
Purification:
Protein G affinity purified
Application:
IP, WB, ICC, IHC (PS)
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express Exoc4.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express Exoc4.
Immunogen:
Recombinant rat rSec8.
Predicted Species Reactivity:
Human, Mouse, Rat, Bovine, Dog, Chicken, Fish, Guinea Pig, Hamster, Monkey, Pig, Rabbit, Sheep
Product Format:
Liquid. PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
Reconstitution and Storage:
Store at -20C. Avoid freeze/thaw cycles.
Concentration:
1.0 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-Exoc4 (OAED00236) antibody
Clone:
14G1
Isotype:
IgG1
Application Info:
IP: 12.5 ug/ml
WB: 1:1000, colorimetric
Optimal dilutions should be determined by the end user.

Product Reviews

Protocol:
Tips Information:

Tell us what you think about this item!

Write A Review
    Please, wait...