No. | Gene | SKU | Publication | Pubmed Link |
---|---|---|---|---|
1 | 5-methyl cytosine | AMM99021 | Maki, W. C. et al. Nanowire-transistor based ultra-sensitive DNA methylation detection. Biosens. Bioelectron. 23, 780-7 (2008). 17936611 | 17936611 |
2 | 5-methyl cytosine | AMM99021 | Zhang, W., Lee, H.-R., Koo, D.-H. & Jiang, J. Epigenetic modification of centromeric chromatin: hypomethylation of DNA sequences in the CENH3-associated chromatin in Arabidopsis thaliana and maize. Plant Cell 20, 25-34 (2008). 18239133 | 18239133 |
3 | 5-methyl cytosine | AMM99021 | Jensen, T. J., Novak, P., Eblin, K. E., Gandolfi, A. J. & Futscher, B. W. Epigenetic remodeling during arsenical-induced malignant transformation. Carcinogenesis 29, 1500-8 (2008). 18448484 | 18448484 |
4 | 5-methyl cytosine | AMM99021 | Zhang, W., Wang, X., Yu, Q., Ming, R. & Jiang, J. DNA methylation and heterochromatinization in the male-specific region of the primitive Y chromosome of papaya. Genome Res. 18, 1938-43 (2008). 18593814 | 18593814 |
5 | 5-methyl cytosine | AMM99021 | Minardi, D. et al. Prognostic role of global DNA-methylation and histone acetylation in pT1a clear cell renal carcinoma in partial nephrectomy specimens. J. Cell. Mol. Med. 13, 2115-21 (2009). 18752633 | 18752633 |
6 | 5-methyl cytosine | AMM99021 | Vrba, L., Junk, D. J., Novak, P. & Futscher, B. W. p53 induces distinct epigenetic states at its direct target promoters. BMC Genomics 9, 486 (2008). 18922183 | 18922183 |
7 | 5-methyl cytosine | AMM99021 | Walsh, T. K. et al. A functional DNA methylation system in the pea aphid, Acyrthosiphon pisum. Insect Mol. Biol. 19 Suppl 2, 215-28 (2010). 20482652 | 20482652 |
8 | 5-methyl cytosine | AMM99021 | Ribas, R. et al. Members of the TEAD family of transcription factors regulate the expression of Myf5 in ventral somitic compartments. Dev. Biol. 355, 372-80 (2011). 21497756 | 21497756 |
9 | 5-methyl cytosine | AMM99021 | Macaulay, E. C., Weeks, R. J., Andrews, S. & Morison, I. M. Hypomethylation of functional retrotransposon-derived genes in the human placenta. Mamm. Genome 22, 722-35 (2011). 21874386 | 21874386 |
10 | 5-methyl cytosine | AMM99021 | Kurita, R., Arai, K., Nakamoto, K., Kato, D. & Niwa, O. Determination of DNA methylation using electrochemiluminescence with surface accumulable coreactant. Anal. Chem. 84, 1799-803 (2012). 22263690 | 22263690 |
11 | 5-methyl cytosine | AMM99021 | Kurita, R. & Niwa, O. DNA methylation analysis triggered by bulge specific immuno-recognition. Anal. Chem. 84, 7533-8 (2012). 22880797 | 22880797 |
12 | 5-methyl cytosine | AMM99021 | Gertych, A., Oh, J. H., Wawrowsky, K. A., Weisenberger, D. J. & Tajbakhsh, J. 3-D DNA methylation phenotypes correlate with cytotoxicity levels in prostate and liver cancer cell models. BMC Pharmacol. Toxicol. 14, 11 (2013). 23394161 | 23394161 |
13 | 5-methyl cytosine | AMM99021 | Tajbakhsh, J. Covisualization of methylcytosine, global DNA, and protein biomarkers for In Situ 3D DNA methylation phenotyping of stem cells. Methods Mol. Biol. 1052, 77-88 (2013). 23592032 | 23592032 |
14 | 5-methyl cytosine | AMM99021 | Fukuda, K. et al. Regional DNA methylation differences between humans and chimpanzees are associated with genetic changes, transcriptional divergence and disease genes. J. Hum. Genet. 58, 446-54 (2013). 23739127 | 23739127 |
15 | 5-Methylcytosine | AMM99021 | Microplate-based platform for combined chromatin and DNA methylation immunoprecipitation assays. BMC Mol Biol. 12, 49 (2011). 22098709 | 22098709 |
16 | 5-Methylcytosine | AMM99021 | Physical localization and DNA methylation of 45S rRNA gene loci in Jatropha curcas L. PLoS One. 8, e84284 (2014). 24386362 | 24386362 |
17 | 5-Methylcytosine | AMM99021 | The Sm protein methyltransferase PRMT5 is not required for primordial germ cell specification in mice. EMBO J. 34, 748-58 (2015). 25519955 | 25519955 |
18 | 5-Methylcytosine | AMM99021 | Dynamic heterogeneity of DNA methylation and hydroxymethylation in embryonic stem cell populations captured by single-cell 3D high-content analysis. Exp Cell Res. 332, 190-201 (2015). 25700729 | 25700729 |
19 | 5-Methylcytosine | AMM99021 | Primate Primordial Germ Cells Acquire Transplantation Potential by Carnegie Stage 23. Stem Cell Reports. 9, 329-341 (2017). 28579394 | 28579394 |
20 | 5-Methylcytosine | AMM99021 | Prostate cancer diagnosis using epigenetic biomarkers, 3D high-content imaging and probabilistic cell-by-cell classifiers. Oncotarget. 8, 57278-57301 (2017). 28915670 | 28915670 |
21 | 5-Methylcytosine | AMM99021 | Utility of 5-Methylcytosine Immunohistochemical Staining to Assess Global DNA Methylation and Its Prognostic Impact in MDS Patients. Asian Pac J Cancer Prev. 18, 3307-3313 (2017). 29286224 | 29286224 |
22 | 5-Methylcytosine | AMM99021 | PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation. Stem Cell Res. 27, 46-56 (2018). 29324254 | 29324254 |
23 | 5-Methylcytosine | AMM99021 | Siyuan Chang, et al. Epigenetic regulation of osteopontin splicing isoform c defines its role as a microenvironmental factor to promote the survival of colon cancer cells from 5-FU treatment. 452 (2020). 32944000 | 32944000 |
24 | 5-Methylcytosine | AMM99021 | Global acetylation and methylation changes predict papillary urothelial neoplasia of low malignant potential recurrence: a quantitative analysis. Int J Immunopathol Pharmacol. 24, 489-97 (2011) 21658323 | 21658323 |
25 | 5-Methylcytosine | AMM99021 | Conformation-selective methylation of geminivirus DNA. J Virol. 85, 12001-12 (2011) 21835804 | 21835804 |
26 | 5-Methylcytosine | AMM99021 | Single cell epigenetic visualization assay. Nucleic Acids Res. (2021). 33511400 | 33511400 |
27 | AADC | ARP41425_T100 | Ts1Cje Down syndrome model mice exhibit environmental stimuli-triggered locomotor hyperactivity and sociability concurrent with increased flux through central dopamine and serotonin metabolism. Exp. Neurol. 293, 1-12 (2017). 28336394 | 28336394 |
28 | ABCC4 | OAEB02455 | Xu, S., Weerachayaphorn, J., Cai, S.-Y., Soroka, C. J. & Boyer, J. L. Aryl hydrocarbon receptor and NF-E2-related factor 2 are key regulators of human MRP4 expression. Am. J. Physiol. Gastrointest. Liver Physiol. 299, G126-35 (2010). 20395535 | 20395535 |
29 | ABCC4 | OAEB02455 | Weerachayaphorn, J. et al. Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine. Am. J. Physiol. Gastrointest. Liver Physiol. 302, G925-36 (2012). 22345550 | 22345550 |
30 | ABCC4 | OAEB02455 | Gori, I. et al. Augmented epithelial multidrug resistance-associated protein 4 expression in peritoneal endometriosis: regulation by lipoxin A(4). Fertil. Steril. 99, 1965-73.e2 (2013). 23472950 | 23472950 |
31 | ABCC4 | OAEB02455 | Montani, M. et al. Multidrug resistance protein 4 (MRP4) expression in prostate cancer is associated with androgen signaling and decreases with tumor progression. Virchows Arch. 462, 437-43 (2013). 23503867 | 23503867 |
32 | ABCC8 | ARP43622_P050 | Characterization of acquired paclitaxel resistance of breast cancer cells and involvement of ABC transporters. Toxicol. Appl. Pharmacol. 310, 215-228 (2016). 27664577 | 27664577 |
33 | ABCG1 | OAAB03522 | Fu, Y. et al. ABCA12 Regulates ABCA1-Dependent Cholesterol Efflux from Macrophages and the Development of Atherosclerosis. Cell Metab. 18, 225-38 (2013). 23931754 | 23931754 |
34 | ABL1 | OAAF07465 | Retinal Pigment Epithelium and Neural Retinal Progenitors Interact via Semaphorin 6D to Facilitate Optic Cup Morphogenesis. Eneuro 2021 3 8 NULL 33811086 | 33811086 |
35 | ABP1 | ARP41908_P050 | Liang, X.-H. et al. Estrogen regulates amiloride-binding protein 1 through CCAAT/enhancer-binding protein-beta in mouse uterus during embryo implantation and decidualization. Endocrinology 151, 5007-16 (2010). 20668027 | 20668027 |
36 | ACAA1 | ARP48177_P050 | Mouse hepatocytes and LSEC proteome reveal novel mechanisms of ischemia/reperfusion damage and protection by A2aR stimulation. J Hepatol 573-80 62 3 March 2015 | 25315650 |
37 | ACADVL | ARP54486_P050 | Yoon, S.-W., Kang, S., Ryu, S.-E. & Poo, H. Identification of tyrosine-nitrated proteins in HT22 hippocampal cells during glutamate-induced oxidative stress. Cell Prolif. 43, 584-93 (2010). 21039997 | 21039997 |
38 | ACE2 | ARP53751_P050 | ACE2 Therapy Using Adeno-associated Viral Vector Inhibits Liver Fibrosis in Mice. Mol. Ther. 23, 1434-43 (2015). 25997428 | 25997428 |
39 | ACE2 | ARP53751_P050 | Plasma and tissue angiotensin-converting enzyme 2 activity and plasma equilibrium concentrations of angiotensin peptides in dogs with heart disease. J Vet Intern Med. 33, 1571-1584 (2019). 31254308 | 31254308 |
40 | ACE2 | ARP53751_P050 | Tropism of SARS-CoV-2, SARS-CoV and influenza virus in canine tissue explants. J Infect Dis. (2021). 33395484 | 33395484 |
41 | ACLY | ARP42737_P050 | Infantino, V., Iacobazzi, V., Palmieri, F. & Menga, A. ATP-citrate lyase is essential for macrophage inflammatory response. Biochem. Biophys. Res. Commun. 440, 105-11 (2013). 24051091 | 24051091 |
42 | ACLY | ARP42737_P050 | Acetyl-CoA Metabolism Supports Multistep Pancreatic Tumorigenesis. Cancer Discov. 9, 416-435 (2019). 30626590 | 30626590 |
43 | ACLY | OAGA04026 | ATP-citrate lyase promotes axonal transport across species. Nat Commun. 12, 5878 (2021) 34620845 | 34620845 |
44 | ACLY | OASG00647 | Modulation of matrix metabolism by ATP-citrate lyase in articular chondrocytes. J Biol Chem. 293, 12259-12270 (2018). 29929979 | 29929979 |
45 | ACO1 | ARP40390_P050 | Saturated Fatty Acid Activates T Cell Inflammation Through a Nicotinamide Nucleotide Transhydrogenase (NNT)-Dependent Mechanism. Biomolecules. 9, (2019). 30823587 | 30823587 |
46 | ACO2 | ARP56302_P050 | Scheving, R. et al. Protein S-nitrosylation and denitrosylation in the mouse spinal cord upon injury of the sciatic nerve. J. Proteomics 75, 3987-4004 (2012). 22588120 | 22588120 |
47 | ACSL1 | ARP32784_P050 | Golej, D. L. et al. Long-chain acyl-CoA synthetase 4 modulates prostaglandin E₂ release from human arterial smooth muscle cells. J. Lipid Res. 52, 782-93 (2011). 21242590 | 21242590 |
48 | ACTB | OAAD00224 | Selective cytoprotective effect of histamine on doxorubicin-induced hepatic and cardiac toxicity in animal models. Cell Death Discov. 1, 15059 (2015). 27551485 | 27551485 |
49 | ACTN2 | ARP41462_P050 | Yan, Z. et al. BAF250B-associated SWI/SNF chromatin-remodeling complex is required to maintain undifferentiated mouse embryonic stem cells. Stem Cells 26, 1155-65 (2008). 18323406 | 18323406 |
50 | ACTN4 | ARP42202_T100 | Wei, S., Gao, X., Du, J., Su, J. & Xu, Z. Angiogenin enhances cell migration by regulating stress fiber assembly and focal adhesion dynamics. PLoS One 6, e28797 (2011). 22194915 | 22194915 |
51 | ACVR2A | OAAB16873 | Detection of Sotatercept (ACE-011) in human serum by SAR-PAGE and western single blotting. Drug Test Anal 927-937 10 6 June 2018 | 29193906 |
52 | ADAM10 | OAGA02442 | Sogorb-Esteve, A., García-Ayllón, M., Gobom, J., Alom, J., Zetterberg, H., Blennow, K. and Sáez-Valero, J. Levels of ADAM10 are reduced in Alzheimer’s disease CSF. J Neuroinflammation. 15, 213 (2018). 30045733 | 30045733 |
53 | ADAM10 | OAGA02442 | α-Secretase nonsense mutation (ADAM10 Tyr167*) in familial Alzheimer's disease. Alzheimers Res Ther. 12, 139 (2020). 33129344 | 33129344 |
54 | ADAMTS4 | ARP41556_P050 | Lee, C. W. et al. Comparison of ADAMTS-1, -4 and -5 expression in culprit plaques between acute myocardial infarction and stable angina. J. Clin. Pathol. 64, 399-404 (2011). 21345877 | 21345877 |
55 | ADAMTS4 | ARP41556_P050 | Boerboom, D. et al. Partially redundant functions of Adamts1 and Adamts4 in the perinatal development of the renal medulla. Dev. Dyn. 240, 1806-14 (2011). 21584905 | 21584905 |
56 | ADAMTS4 | ARP41556_P050 | Lee, S.-Y. et al. Differential expression patterns of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) -1, -4, -5, and -14 in human placenta and gestational trophoblastic diseases. Arch. Pathol. Lab. Med. 138, 643-50 (2014). 24786121 | 24786121 |
57 | ADCYAP1R1 | ARP59945_P050 | PACAP modulation of calcium ion activity in developing granule cells of the neonatal mouse olfactory bulb. J Neurophysiol. 113, 1234-48 (2015). 25475351 | 25475351 |
58 | ADGRG1 | ARP58627_P050 | Targeting HOTAIRM1 ameliorates glioblastoma by disrupting mitochondrial oxidative phosphorylation and serine metabolism. iScience 104823 25 8 August 2022 | 35992092 |
59 | ADH4 | ARP43572_P050 | Retinoid regulation of antiviral innate immunity in hepatocytes. Hepatology. 63, 1783-95 (2016). 26638120 | 26638120 |
60 | ADH4 | ARP43573_T100 | Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 | 24465277 |
61 | ADIPOR2 | ARP60819_P050 | Effects of Obesity on Adiponectin System Skin Expression in Dogs: A Comparative Study. Animals (Basel). 11, NULL (2021) 34438765 | 34438765 |
62 | ADORA1 | OABF01723 | Adenosine A1 Receptor mRNA Expression by Neurons and Glia in the Auditory Forebrain. Anat Rec (Hoboken). 301, 1882-1905 (2018). 30315630 | 30315630 |
63 | ADORA2A | OALA02443 | Toll-like receptor 2 induces adenosine receptor A2a and promotes human squamous carcinoma cell growth via extracellular signal regulated kinases ½. Oncotarget. 9, 6814-6829 (2018). 29467931 | 29467931 |
64 | ADORA3 | ARP59956_P050 | Merighi, S. et al. Hypoxia inhibits paclitaxel-induced apoptosis through adenosine-mediated phosphorylation of bad in glioblastoma cells. Mol. Pharmacol. 72, 162-72 (2007). 17400763 | 17400763 |
65 | ADPRHL2 | OAAB06322 | Structural and biochemical analysis of human ADP-ribosyl-acceptor hydrolase 3 (ARH3) reveals the basis of metal selectivity and different roles for the two Mg ions. J Biol Chem 2021 NULL NULL 100692 33894202 | 33894202 |
66 | AEBP1 | ARP31592_P050 | Kim, H. J. et al. Identification of estradiol/ERa-regulated genes in the mouse pituitary. J. Endocrinol. 210, 309-21 (2011). 21700660 | 21700660 |
67 | AGPAT2 | ARP44636_P050 | Fetuin-A modulates lipid mobilization in bovine adipose tissue by enhancing lipogenic activity of adipocytes. J Dairy Sci. 102, 4628-4638 (2019). 30827564 | 30827564 |
68 | AHR | ARP32243_T100 | The AhR Ligand, TCDD, Regulates Androgen Receptor Activity Differently in Androgen-Sensitive versus Castration-Resistant Human Prostate Cancer Cells. Int J Environ Res Public Health. 12, 7506-18 (2015). 26154658 | 26154658 |
69 | AIF1 | OAGA00004 | Adverse early life environment increases hippocampal microglia abundance in conjunction with decreased neural stem cells in juvenile mice. Int. J. Dev. Neurosci. 55, 56-65 (2016). 27666383 | 27666383 |
70 | AIF1 | OAGA00004 | Histological Changes of the Testicular Interstitium during Postnatal Development in Microminipigs. Toxicol Pathol. 47, 469-482 (2019). 30739565 | 30739565 |
71 | AIF1 | OAGA00004 | Spontaneous Age-Related Histopathological Changes in Microminipigs. Toxicol Pathol. 47, 817-832 (2019). 31337280 | 31337280 |
72 | AKR1B10 | OAGA00776 | LncRNA 1700020I14Rik promotes AKR1B10 expression and activates Erk pathway to induce hepatocyte damage in alcoholic hepatitis. Cell Death Discov 374 8 1 August 2022 | 36028503 |
73 | AKR1C1 | OAGA00409 | Androgen receptor signalling in the male adrenal facilitates X-zone regression, cell turnover and protects against adrenal degeneration during ageing. Sci Rep. 9, 10457 (2019). 31320667 | 31320667 |
74 | AKR1C1 | OAGA00409 | Androgen Receptor Is Dispensable for X-Zone Regression in the Female Adrenal but Regulates Post-Partum Corticosterone Levels and Protects Cortex Integrity. Front Endocrinol (Lausanne). 11, 599869 (2021). 33584538 | 33584538 |
75 | AKT | OAAF00965 | Tsai, T.-C. et al. The paracrine effect of exogenous growth hormone alleviates dysmorphogenesis caused by tbx5 deficiency in zebrafish (Danio rerio) embryos. J. Biomed. Sci. 19, 63 (2012). 22776023 | 22776023 |
76 | AKT1 | AVARP06008_P050 | The RNA helicase DDX3 induces neural crest by promoting AKT activity. Development. NULL, NULL (2020) 33318149 | 33318149 |
77 | AKT1 | AVARP06008_P050 | The RNA helicase DDX3 induces neural crest by promoting AKT activity. Development 2020 NULL NULL NULL 34004944 | 34004944 |
78 | ALAD | ARP41657_P050 | Iron metabolic pathways in the processes of sponge plasticity. PLoS One. 15, e0228722 (2020). 32084159 | 32084159 |
79 | ALB | ARP41746_P050 | Holzer, M. et al. Uremia alters HDL composition and function. J. Am. Soc. Nephrol. 22, 1631-41 (2011). 21804091 | 21804091 |
80 | ALG11 | ARP44463_P050 | Rind, N. et al. A severe human metabolic disease caused by deficiency of the endoplasmatic mannosyltransferase hALG11 leads to congenital disorder of glycosylation-Ip. Hum. Mol. Genet. 19, 1413-24 (2010). 20080937 | 20080937 |
81 | ALKBH1 | OACA06689 | ALKBH1-demethylated DNA N6-methyladenine modification triggers vascular calcification via osteogenic reprogramming in chronic kidney disease. J Clin Invest. 131, NULL (2021) 34003800 | 34003800 |
82 | AMH | ARP54312_P050 | Tezak, B., I. Romero, S. Milton and J. Wyneken. Identifying Sex of Neonate Turtles with Temperature-dependent Sex Determination via Small Blood Samples. Sci Rep. 2020; 10: 5012. 32193464 | 32193464 |
83 | AMH | ARP54312_P050 | Decreased Anti-Müllerian hormone and Anti-Müllerian hormone receptor type 2 in hypothalami of old Japanese Black cows. J Vet Med Sci. 82, 1113-1117 (2020). 32554955 | 32554955 |
84 | AMH | ARP54312_P050 | Bovine gonadotrophs express anti-Müllerian hormone (AMH): comparison of AMH mRNA and protein expression levels between old Holsteins and young and old Japanese Black females. Reprod Fertil Dev. 31, 810-819 (2019) 30554590 | 30554590 |
85 | AMH | ARP54312_P050 | Anti-Müllerian hormone and its receptor are detected in most gonadotropin-releasing-hormone cell bodies and fibers in heifer brains. Domest Anim Endocrinol. 72, 106432 (2020) 32169754 | 32169754 |
86 | AMH | OAAB06540 | Structure of AMH bound to AMHR2 provides insight into a unique signaling pair in the TGF-β family. Proc Natl Acad Sci U S A. 118 (2021) 34155118 | 34155118 |
87 | AMOT | ARP34660_P050 | VCAM-1 induces signals that stimulate ZO-1 serine phosphorylation and reduces ZO-1 localization at lung endothelial cell junctions. J Leukoc Biol. 104, 215-228 (2018). 29889984 | 29889984 |
88 | ANK1 | ARP42566_T100 | Obscurin determines the architecture of the longitudinal sarcoplasmic reticulum. J Cell Sci. 122, 2640-50 (2009). 19584095 | 19584095 |
89 | ANK1 | ARP42566_T100 | Cytoplasmic gamma-actin and tropomodulin isoforms link to the sarcoplasmic reticulum in skeletal muscle fibers. J Cell Biol. 194, 105-20 (2011). 21727195 | 21727195 |
90 | ANK1 | ARP42566_T100 | Obscurin and KCTD6 regulate cullin-dependent small ankyrin-1 (sAnk1.5) protein turnover. Mol Biol Cell. 23, 2490-504 (2012). 22573887 | 22573887 |
91 | ANK1 | ARP42566_T100 | Impaired muscle relaxation and mitochondrial fission associated with genetic ablation of cytoplasmic actin isoforms. FEBS J. 285, 481-500 (2018). 29265728 | 29265728 |
92 | ANKH | OAAB06341 | Szeri, et al. The membrane protein ANKH is crucial for bone mechanical performance by mediating cellular export of citrate and ATP. PLoS Genetics 2020 Jul 8;16(7):e1008884. 32639996 | 32639996 |
93 | ANKH | OAAB06341 | The Mineralization Regulator ANKH Mediates Cellular Efflux of ATP, Not Pyrophosphate. J Bone Miner Res 1024-1031 37 5 May 2022 | 35147247 |
94 | ANKRD11 | ARP33542_T100 | Characterization of ANKRD11 mutations in humans and mice related to KBG syndrome. Hum Genet 2015 2 134 181-90 25413698 | 25413698 |
95 | ANO4 | OACA04834 | Influence of Anoctamin-4 and -9 on ADAM10 and ADAM17 Sheddase Function. Membranes (Basel) 2022 2 12 NULL 35207044 | 35207044 |
96 | ANXA1 | ARP36568_T100 | Nordon, I. M. et al. Comparative proteomics reveals a systemic vulnerability in the vasculature of patients with abdominal aortic aneurysms. J. Vasc. Surg. 54, 1100-1108.e6 (2011). 21741794 | 21741794 |
97 | ANXA1 | ARP36568_T100 | Ishida, Y. et al. Carnosol, rosemary ingredient, induces apoptosis in adult T-cell leukemia/lymphoma cells via glutathione depletion: proteomic approach using fluorescent two-dimensional differential gel electrophoresis. Hum. Cell 27, 68-77 (2014). 24323765 | 24323765 |
98 | ANXA2 | OAAF00618 | Annexin A2 binds the internal ribosomal entry site of c-myc mRNA and regulates its translation. RNA Biol 2021 sup1 18 337-354 34346292 | 34346292 |
99 | ANXA3 | ARP36578_T100 | Seliger, B. et al. Combined analysis of transcriptome and proteome data as a tool for the identification of candidate biomarkers in renal cell carcinoma. Proteomics 9, 1567-81 (2009). 19235166 | 19235166 |
100 | ANXA3 | ARP36578_T100 | Schordan, S. et al. Alterations of the podocyte proteome in response to high glucose concentrations. Proteomics 9, 4519-28 (2009). 19688724 | 19688724 |
101 | ANXA3 | ARP36578_T100 | Bianchi, C. et al. Primary cell cultures from human renal cortex and renal-cell carcinoma evidence a differential expression of two spliced isoforms of Annexin A3. Am. J. Pathol. 176, 1660-70 (2010). 20167856 | 20167856 |
102 | ANXA3 | ARP36578_T100 | Meyer-Schwesinger, C. et al. Nephrotic syndrome and subepithelial deposits in a mouse model of immune-mediated anti-podocyte glomerulonephritis. J. Immunol. 187, 3218-29 (2011). 21844386 | 21844386 |
103 | ANXA4 | ARP36686_T100 | de la Cuesta, F. et al. A proteomic focus on the alterations occurring at the human atherosclerotic coronary intima. Mol. Cell. Proteomics 10, M110.003517 (2011). 21248247 | 21248247 |
104 | ANXA4 | ARP36686_T100 | Staquicini, F. I. et al. Vascular ligand-receptor mapping by direct combinatorial selection in cancer patients. Proc. Natl. Acad. Sci. U. S. A. 108, 18637-42 (2011). 22049339 | 22049339 |
105 | AOC1 | ARP41908_P050 | Newly developed reversible MAO-B inhibitor circumvents the shortcomings of irreversible inhibitors in Alzheimer's disease. Sci Adv. 5, eaav0316 (2019). 30906861 | 30906861 |
106 | APOE | ARP54283_P050 | Rohn, T. T., Catlin, L. W., Coonse, K. G. & Habig, J. W. Identification of an amino-terminal fragment of apolipoprotein E4 that localizes to neurofibrillary tangles of the Alzheimer’s disease brain. Brain Res. 1475, 106-15 (2012). 22902767 | 22902767 |
107 | APOE | ARP54283_P050 | Rohn, T. T., Day, R. J., Sheffield, C. B., Rajic, A. J. & Poon, W. W. Apolipoprotein E pathology in vascular dementia. Int. J. Clin. Exp. Pathol. 7, 938-47 (2014). 24696712 | 24696712 |
108 | APOE | ARP54283_P050 | Proteolytic Cleavage of Apolipoprotein E in the Down Syndrome Brain. Aging Dis. 7, 267-77 (2016). 27330841 | 27330841 |
109 | APOE | ARP54283_P050 | Nuclear uptake of an amino-terminal fragment of apolipoprotein E4 promotes cell death and localizes within microglia of the Alzheimer's disease brain. Int J Physiol Pathophysiol Pharmacol. 9, 40-57 (2017). 28533891 | 28533891 |
110 | APOE | ARP54283_P050 | Evaluation of Apolipoprotein E Fragmentation as a Biomarker for Alzheimer's Disease. J Neurol Neurol Disord. 3, (2017). 29520379 | 29520379 |
111 | APOE | ARP54283_P050 | Fragmentation of Apolipoprotein E4 is Required for Differential Expression of Inflammation and Activation Related Genes in Microglia Cells. Int J Neurodegener Dis 2021 1 4 NULL 34693295 | 34693295 |
112 | APOO | OAAB09635 | Adult-onset obesity is triggered by impaired mitochondrial gene expression. Sci Adv. 3, e1700677 (2017). 28835921 | 28835921 |
113 | APTX | ARP40014_T100 | Dopeso, H. et al. Aprataxin tumor levels predict response of colorectal cancer patients to irinotecan-based treatment. Clin. Cancer Res. 16, 2375-82 (2010). 20371676 | 20371676 |
114 | AQp4 | OABB01958 | Astrogliogenesis in human fetal brain: complex spatiotemporal immunoreactivity patterns of GFAP, S100, AQP4 and YKL-40. J Anat 2019 3 235 590-615 30901080 | 30901080 |
115 | AQUAPORIN 4 | OABB01958 | PDGF-B Is Required for Development of the Glymphatic System. Cell Rep. 26, 2955-2969.e3 (2019). 30865886 | 30865886 |
116 | AREB6 | ARP30976_P050 | Kothandaraman, N. et al. E2F5 status significantly improves malignancy diagnosis of epithelial ovarian cancer. BMC Cancer 10, 64 (2010). 20181230 | 20181230 |
117 | ARF6 | ARP54598_P050 | Arf6 regulates the cycling and the readily releasable pool of synaptic vesicles at hippocampal synapse. Elife. 5, (2016). 26731518 | 26731518 |
118 | ARG1 | ARP45672_T100 | Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 | 24465277 |
119 | ARG1 | OAEB02142 | Jäger, K. et al. Enzymes of urea synthesis are expressed at the ocular surface, and decreased urea in the tear fluid is associated with dry-eye syndrome. Graefes Arch. Clin. Exp. Ophthalmol. 251, 1995-2002 (2013). 23740519 | 23740519 |
120 | ARHGDIA | OAAI00735 | α2β1 integrins spatially restrict Cdc42 activity to stabilise adherens junctions. BMC Biol 2021 1 19 130 34158053 | 34158053 |
121 | ARHGEF7 | OASG05888 | Platelet-derived growth factor receptor-a and Ras-related C3 botulinum toxin substrate-1 regulate mechano-responsiveness of lung fibroblasts. Am J Physiol Lung Cell Mol Physiol. 313, L1174-L1187 (2017). 28775097 | 28775097 |
122 | ARNT | ARP30979_P050 | Human placental renin-angiotensin system in normotensive and pre-eclamptic pregnancies at high altitude and after acute hypoxia-reoxygenation insult. J. Physiol. (Lond.). 26574162 | 26574162 |
123 | ASAH1 | OAPB00726 | Increased placental mitochondrial fusion in gestational diabetes mellitus: an adaptive mechanism to optimize feto-placental metabolic homeostasis?. BMJ Open Diabetes Res Care. 8, (2020). 32144130 | 32144130 |
124 | ASAHL | ARP44939_P050 | A quantitative study on splice variants of N-acylethanolamine acid amidase in human prostate cancer cells and other cells. Biochim. Biophys. Acta. 1861, 1951-1958 (2016). 27693242 | 27693242 |
125 | ASCL1 | ARP32355_T100 | Vias, M. et al. Pro-neural transcription factors as cancer markers. BMC Med. Genomics 1, 17 (2008). 18489756 | 18489756 |
126 | ASCL1 | ARP32355_T100 | Suozzi, A., Malatesta, M. & Zancanaro, C. Subcellular distribution of key enzymes of lipid metabolism during the euthermia-hibernation-arousal cycle. J. Anat. 214, 956-62 (2009). 19538638 | 19538638 |
127 | ASGP2 | ARP33820_P050 | Chang, T.-C. et al. Synthesis and evaluation of a photoactive probe with a multivalent carbohydrate for capturing carbohydrate-lectin interactions. Bioconjug. Chem. 24, 1895-906 (2013). 24151840 | 24151840 |
128 | ASS1 | ARP41366_T100 | Aberrant expression and distribution of enzymes of the urea cycle and other ammonia metabolizing pathways in dogs with congenital portosystemic shunts. PLoS One. 9, e100077 (2014). 24945279 | 24945279 |
129 | ASS1 | ARP41366_T100 | Argininosuccinate neurotoxicity and prevention by creatine in argininosuccinate lyase deficiency: An in vitro study in rat three-dimensional organotypic brain cell cultures. J Inherit Metab Dis. 42, 1077-1087 (2019) 30907007 | 30907007 |
130 | ASS1 | ARP41367_T100 | Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 | 24465277 |
131 | ATF4 | ARP37017_P050 | Methods for monitoring endoplasmic reticulum stress and the unfolded protein response. Int J Cell Biol. 2010, 830307 (2010). 20169136 | 20169136 |
132 | ATF4 | ARP37017_P050 | Alger, H. M., Rayavarapu, S. & Nagaraju, K. Measurement of activation of the endoplasmic reticulum stress response in autoimmune myositis. Methods Enzymol. 489, 207-25 (2011). 21266232 | 21266232 |
133 | ATF4 | ARP37017_P050 | Drivas, T. G., Holzbaur, E. L. F. & Bennett, J. Disruption of CEP290 microtubule/membrane-binding domains causes retinal degeneration. J. Clin. Invest. 123, 4525-39 (2013). 24051377 | 24051377 |
134 | ATF4 | ARP37017_P050 | Schneeberger, M. et al. Mitofusin 2 in POMC Neurons Connects ER Stress with Leptin Resistance and Energy Imbalance. Cell 155, 172-87 (2013). 24074867 | 24074867 |
135 | ATF4 | ARP37017_P050 | Cross-Talk Between FSH and Endoplasmic Reticulum Stress: A Mutually Suppressive Relationship. Reprod Sci. 23, 352-64 (2016). 26342052 | 26342052 |
136 | ATF4 | ARP37017_P050 | Glutathione S-Transferase P-Mediated Protein S-Glutathionylation of Resident Endoplasmic Reticulum Proteins Influences Sensitivity to Drug-Induced Unfolded Protein Response. Antioxid. Redox Signal. 26, 247-261 (2017). 26838680 | 26838680 |
137 | ATF4 | ARP37017_P050 | The integrated stress response in hypoxia-induced diffuse white matter injury. J Neurosci. (2017). 28720571 | 28720571 |
138 | ATF4 | ARP37017_P050 | IER3IP1 deficiency leads to increased β-cell death and decreased β-cell proliferation. Oncotarget. 8, 56768-56779 (2017). 28915629 | 28915629 |
139 | ATF4 | ARP37017_P050 | Deficiency of VCP-Interacting Membrane Selenoprotein (VIMP) Leads to G1 Cell Cycle Arrest and Cell Death in MIN6 Insulinoma Cells. Cell Physiol Biochem. 51, 2185-2197 (2018). 30537728 | 30537728 |
140 | ATF4 | ARP37017_P050 | Mast Cells Induce Blood Brain Barrier Damage in SCD by Causing Endoplasmic Reticulum Stress in the Endothelium. Front Cell Neurosci. 13, 56 (2019). 30837844 | 30837844 |
141 | ATF4 | ARP37017_P050 | Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation. Cell Stem Cell. 25, 531-541.e6 (2019). 31585094 | 31585094 |
142 | ATF4 | ARP38066_P050 | Kalinec, G. M. et al. Acetaminophen and NAPQI are toxic to auditory cells via oxidative and endoplasmic reticulum stress-dependent pathways. Hear. Res. 313, 26-37 (2014). 24793116 | 24793116 |
143 | ATF6 | ARP32293_P050 | Exclusion of the unfolded protein response in light-induced retinal degeneration in the canine T4R RHO model of autosomal dominant retinitis pigmentosa. PLoS One. 10, e0115723 (2015). 25695253 | 25695253 |
144 | ATG4B | OAAF02774 | NKCT1 (purified Naja kaouthia protein toxin) conjugated gold nanoparticles induced Akt/mTOR inactivation mediated autophagic and caspase 3 activated apoptotic cell death in leukemic cell. Toxicon. 121, 86-97 (2016). 27527270 | 27527270 |
145 | ATOH1 | ARP32365_P050 | Regenerating hair cells in vestibular sensory epithelia from humans. Elife. 7, (2018). 30019672 | 30019672 |
146 | ATP1B1 | ARP44411_P050 | Dec1 and CLOCK Regulate Na+/K+-ATPase β1 Subunit Expression and Blood Pressure. Hypertension. 72, 746-754 (2018). 30012868 | 30012868 |
147 | Atp1b2 | ARP45156_P050 | Li, Y.-G. et al. 1-deoxynojirimycin inhibits glucose absorption and accelerates glucose metabolism in streptozotocin-induced diabetic mice. Sci. Rep. 3, 1377 (2013). 23536174 | 23536174 |
148 | Atp1b2 | ARP45156_P050 | Li, Y.-G., Ji, D.-F., Zhong, S., Lv, Z.-Q. & Lin, T.-B. Cooperative anti-diabetic effects of deoxynojirimycin-polysaccharide by inhibiting glucose absorption and modulating glucose metabolism in streptozotocin-induced diabetic mice. PLoS One 8, e65892 (2013). 23755289 | 23755289 |
149 | ATP5B | ARP48185_T100 | Li, N., Bates, D. J., An, J., Terry, D. A. & Wang, E. Up-regulation of key microRNAs, and inverse down-regulation of their predicted oxidative phosphorylation target genes, during aging in mouse brain. Neurobiol. Aging 32, 944-55 (2011). 19487051 | 19487051 |
150 | ATP5B | ARP48185_T100 | Bannister, J. P. et al. Ca(V)1.2 channel N-terminal splice variants modulate functional surface expression in resistance size artery smooth muscle cells. J. Biol. Chem. 286, 15058-66 (2011). 21364284 | 21364284 |
151 | ATP5B | ARP48185_T100 | Guo, J. et al. Protein targets for carbonylation by 4-hydroxy-2-nonenal in rat liver mitochondria. J. Proteomics 74, 2370-9 (2011). 21801862 | 21801862 |
152 | ATP5B | ARP48186_T100 | Rubel, C. E. et al. Diggin’ on u(biquitin): a novel method for the identification of physiological E3 ubiquitin ligase substrates. Cell Biochem. Biophys. 67, 127-38 (2013). 23695782 | 23695782 |
153 | ATP5B | ARP48186_T100 | Teodoro, J. S. et al. Berberine reverts hepatic mitochondrial dysfunction in high-fat fed rats: a possible role for SirT3 activation. Mitochondrion 13, 637-46 (2013). 24041461 | 24041461 |
154 | ATP5B | ARP48186_T100 | Usui, T. et al. Elevated mitochondrial biogenesis in skeletal muscle is associated with testosterone-induced body weight loss in male mice. FEBS Lett. 588, 1935-41 (2014). 24726723 | 24726723 |
155 | ATP5F1B | ARP48185_T100 | A Chinese herbal formula, Jian-Pi-Yi-Shen decoction, improves muscle atrophy via regulating mitochondrial quality control process in 5/6 nephrectomised rats. Sci Rep. 7, 9253 (2017). 28835671 | 28835671 |
156 | ATP5F1B | ARP48185_T100 | Resveratrol Improves Muscle Atrophy by Modulating Mitochondrial Quality Control in STZ-Induced Diabetic Mice. Mol Nutr Food Res. 62, e1700941 (2018). 29578301 | 29578301 |
157 | ATP5F1B | ARP48185_T100 | Antioxidant Apigenin Relieves Age-Related Muscle Atrophy by Inhibiting Oxidative Stress and Hyperactive Mitophagy and Apoptosis in Skeletal Muscle of Mice. J Gerontol A Biol Sci Med Sci. 75, 2081-2088 (2020). 32857105 | 32857105 |
158 | AXL | OAAB17122 | Chemotherapy confers a conserved secondary tolerance to EGFR inhibition via AXL-mediated signaling bypass. Sci Rep. 11, 8016 (2021). 33850249 | 33850249 |
159 | B2GP1 | OPPA01429 | Effects of antibodies against human parvovirus B19 on angiogenic signaling. Mol Med Rep 2020 3 21 1320-1327 31922220 | 31922220 |
160 | BACH2 | ARP39513_P050 | TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate. Cell. 182, 297-316.e27 (2020) 32619424 | 32619424 |
161 | B-ACTIN | ARP40174_P050 | Regular exercise modulates cardiac mast cell activation in ovariectomized rats. J Physiol Sci. 66, 165-73 (2016). 26467449 | 26467449 |
162 | BAG2 | ARP42177_T100 | BAG2 promotes tumorigenesis through enhancing mutant p53 protein levels and function. Elife. 4, (2015). 26271008 | 26271008 |
163 | BASP1 | ARP59932_P050 | Identification of Synaptic DGKθ Interactors That Stimulate DGKθ Activity. Front Synaptic Neurosci 2022 NULL 14 855673 35573662 | 35573662 |
164 | BAX | AVARP02020_T100 | Honda, A. et al. Activation of caspase 3, 9, 12, and Bax in masseter muscle of mdx mice during necrosis. J. Muscle Res. Cell Motil. 28, 243-7 (2007). 17952618 | 17952618 |
165 | BAX | AVARP02020_T100 | De Martino, L. et al. Bid cleavage, cytochrome c release and caspase activation in canine coronavirus-induced apoptosis. Vet. Microbiol. 141, 36-45 (2010). 19781871 | 19781871 |
166 | BCAR1 | OAEB03174 | Platelet-derived growth factor receptor-a and Ras-related C3 botulinum toxin substrate-1 regulate mechano-responsiveness of lung fibroblasts. Am J Physiol Lung Cell Mol Physiol. 313, L1174-L1187 (2017). 28775097 | 28775097 |
167 | BCAT1 | ARP46132_P050 | Ketogenic HMG-CoA lyase and its product β-hydroxybutyrate promote pancreatic cancer progression. EMBO J e110466 41 9 May 2022 | 35307861 |
168 | BCHE | ARP44208_T100 | Immunohistochemical analysis of hippocampal butyrylcholinesterase: Implications for regional vulnerability in Alzheimer's disease. Neuropathology. 36, 135-45 (2016). 26293308 | 26293308 |
169 | BCL2 | OAAF00934 | Fibroblast growth factor 22 is a novel modulator of depression through interleukin-1β. CNS Neurosci Ther. 23, 907-916 (2017). 28948716 | 28948716 |
170 | BCL2 | OAPB00242 | Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention. Cancer Cell. 36, 250-267.e9 (2019). 31526758 | 31526758 |
171 | BDKRB2 | OABF00968 | Pharmacological Modulation of Blood-Brain Barrier Permeability by Kinin Analogs in Normal and Pathologic Conditions. Pharmaceuticals (Basel). 13, NULL (2020). 33003415 | 33003415 |
172 | BDNF | ARP41970_P050 | McCarthy, D. M. et al. Cocaine alters BDNF expression and neuronal migration in the embryonic mouse forebrain. J. Neurosci. 31, 13400-11 (2011). 21940433 | 21940433 |
173 | BDNF | ARP41970_P050 | Horibe, I. et al. Induction of melanogenesis by 4’-O-methylated flavonoids in B16F10 melanoma cells. J. Nat. Med. 67, 705-10 (2013). 23242310 | 23242310 |
174 | BDNF | ARP41970_P050 | TrkB/BDNF signalling patterns the sympathetic nervous system. Nat Commun. 6, 8281 (2015). 26404565 | 26404565 |
175 | BDNF | ARP41970_P050 | Sex differences and estrogen regulation of BDNF gene expression, but not propeptide content, in the developing hippocampus. J. Neurosci. Res. 95, 345-354 (2017). 27870444 | 27870444 |
176 | BDNF | ARP41970_P050 | Reversal Learning Deficits Associated with Increased Frontal Cortical Brain-Derived Neurotrophic Factor Tyrosine Kinase B Signaling in a Prenatal Cocaine Exposure Mouse Model. Dev. Neurosci. 38, 354-364 (2016). 27951531 | 27951531 |
177 | BDNF | ARP41970_P050 | Prenatal Cocaine Exposure Alters BDNF-TrkB Signaling in the Embryonic and Adult Brain. Dev. Neurosci. 38, 365-374 (2016). 28132054 | 28132054 |
178 | BDNF | ARP41970_P050 | The Bdnf and Npas4 genes are targets of HDAC3-mediated transcriptional repression. BMC Neurosci. 20, 65 (2019). 31883511 | 31883511 |
179 | BHMT | ARP41474_T100 | Maclean, K. N., Jiang, H., Greiner, L. S., Allen, R. H. & Stabler, S. P. Long-term betaine therapy in a murine model of cystathionine beta-synthase deficient homocystinuria: decreased efficacy over time reveals a significant threshold effect between elevated homocysteine and thrombotic risk. Mol. Genet. Metab. 105, 395-403 (2012). 22192524 | 22192524 |
180 | BHMT | ARP41474_T100 | Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 | 24465277 |
181 | BHMT | ARP41474_T100 | Sex-specific dysregulation of cysteine oxidation and the methionine and folate cycles in female cystathionine gamma-lyase null mice: a serendipitous model of the methylfolate trap. Biol Open. 4, 1154-62 (2015). 26276101 | 26276101 |
182 | BHMT | ARP41474_T100 | Taurine alleviates repression of betaine-homocysteine S-methyltransferase and significantly improves the efficacy of long-term betaine treatment in a mouse model of cystathionine β-synthase-deficient homocystinuria. FASEB J. 33, 6339-6353 (2019) 30768359 | 30768359 |
183 | BICC1 | OAAB04089 | Bicaudal C mutation causes myc and TOR pathway up-regulation and polycystic kidney disease-like phenotypes in Drosophila. PLoS Genet. 13, e1006694 (2017). 28406902 | 28406902 |
184 | BLZF1 | OAAN01805 | A protumorigenic secretory pathway activated by p53 deficiency in lung adenocarcinoma. J Clin Invest. 131, (2021). 32931483 | 32931483 |
185 | BMP7 | ARP32328_P050 | Kodama, S., Okamoto, T. & Suzuki, M. Sinonasal schwannoma with new bone formation expressing bone morphogenic protein. Int. J. Otolaryngol. 2010, 154948 (2010). 21197441 | 21197441 |
186 | BMP7 | ARP32328_P050 | Okamoto, T., Kodama, S., Nomi, N., Umemoto, S. & Suzuki, M. Expression of bone morphogenic protein in sinonasal inverted papilloma with new bone formation. Allergy Rhinol. (Providence). 2, 16-20 (2011). 22852110 | 22852110 |
187 | BMP7 | ARP32328_P050 | Kitamura, S. et al. The Selection of Peritoneal Mesothelial Cells Is Important for Cell Therapy to Prevent Peritoneal Fibrosis. Tissue Eng. Part A (2013). doi:10.1089/ten.TEA.2013.0130 24007428 | 24007428 |
188 | BMP7 | ARP32329_T100 | Morrissey, C., Brown, L. G., Pitts, T. E. M., Vessella, R. L. & Corey, E. Bone morphogenetic protein 7 is expressed in prostate cancer metastases and its effects on prostate tumor cells depend on cell phenotype and the tumor microenvironment. Neoplasia 12, 192-205 (2010). 20126477 | 20126477 |
189 | BMP7 | ARP32329_T100 | Mae, S.-I. et al. Combination of small molecules enhances differentiation of mouse embryonic stem cells into intermediate mesoderm through BMP7-positive cells. Biochem. Biophys. Res. Commun. 393, 877-82 (2010). 20171952 | 20171952 |
190 | BMP7 | ARP32329_T100 | Yi, T. et al. Regulation of embryonic kidney branching morphogenesis and glomerular development by KISS1 receptor (Gpr54) through NFAT2- and Sp1-mediated Bmp7 expression. J. Biol. Chem. 285, 17811-20 (2010). 20375015 | 20375015 |
191 | BMP7 | ARP32329_T100 | Filion, T. M. et al. Elastomeric osteoconductive synthetic scaffolds with acquired osteoinductivity expedite the repair of critical femoral defects in rats. Tissue Eng. Part A 17, 503-11 (2011). 20818999 | 20818999 |
192 | BMP7 | ARP32329_T100 | Fiaschetti, G. et al. Bone morphogenetic protein-7 is a MYC target with prosurvival functions in childhood medulloblastoma. Oncogene 30, 2823-35 (2011). 21317922 | 21317922 |
193 | BMP7 | ARP32329_T100 | Rui, Y. F. et al. Expression of chondro-osteogenic BMPs in clinical samples of patellar tendinopathy. Knee Surg. Sports Traumatol. Arthrosc. 20, 1409-17 (2012). 21946950 | 21946950 |
194 | BMP7 | ARP32329_T100 | Lovric, V. et al. Effects of demineralized bone matrix on tendon-bone healing in an intra-articular rodent model. Am. J. Sports Med. 40, 2365-74 (2012). 22984131 | 22984131 |
195 | BMP7 | ARP32329_T100 | Whiteland, H. et al. Putative prognostic epithelial-to-mesenchymal transition biomarkers for aggressive prostate cancer. Exp. Mol. Pathol. 95, 220-6 (2013). 23933194 | 23933194 |
196 | BMP7 | ARP32329_T100 | A self-avoidance mechanism in patterning of the urinary collecting duct tree. BMC Dev Biol. 14, 35 (2014). 25205115 | 25205115 |
197 | Bnc1 | ARP33283_P050 | BNC1 deficiency-triggered ferroptosis through the NF2-YAP pathway induces primary ovarian insufficiency. Nat Commun 5871 13 1 October 2022 | 36198708 |
198 | BRCA1 | ARP33338_P050 | Prostate tumor growth is impaired by CtBP1 depletion in high-fat diet-fed mice. Clin Cancer Res. 20, 4086-95 (2014). 24842953 | 24842953 |
199 | C15orf48 | ARP50069_P050 | Signatures of host-pathogen evolutionary conflict reveal MISTR-A conserved MItochondrial STress Response network. PLoS Biol 2020 12 18 e3001045 33370271 | 33370271 |
200 | C1qB | ARP44297_P050 | Kuramoto, A. et al. The formation of immune complexes is involved in the acute phase of periodontal destruction in rats. J. Periodontal Res. 47, 455-62 (2012). 22283745 | 22283745 |
201 | C1qB | ARP44297_P050 | Yoshinaga, Y. et al. Topical application of lipopolysaccharide into gingival sulcus promotes periodontal destruction in rats immunized with lipopolysaccharide. J. Periodontal Res. 47, 674-80 (2012). 22582894 | 22582894 |
202 | C1qB | ARP44297_P050 | Nagano, F. et al. Gram-positive bacteria as an antigen topically applied into gingival sulcus of immunized rat accelerates periodontal destruction. J. Periodontal Res. 48, 420-7 (2013). 23137272 | 23137272 |
203 | C1qB | ARP44297_P050 | Nakatsu, S. et al. Occlusal trauma accelerates attachment loss at the onset of experimental periodontitis in rats. J. Periodontal Res. (2013). doi:10.1111/jre.12109 23808820 | 23808820 |
204 | C1QB | ARP44297_P050 | Histopathological comparison of the onset of peri-implantitis and periodontitis in rats. Clin Oral Implants Res. 28, 163-170 (2017). 26804139 | 26804139 |
205 | C1QB | ARP44297_P050 | The histopathological comparison on the destruction of the periodontal tissue between normal junctional epithelium and long junctional epithelium. J. Periodont. Res. 52, 74-82 (2017). 26957231 | 26957231 |
206 | CACNG4 | OASG04296 | Amplification of a calcium channel subunit CACNG4 increases breast cancer metastasis. EBioMedicine. 52, 102646 (2020). 32062352 | 32062352 |
207 | CALCRL | ARP42260_P050 | Targeting HOTAIRM1 ameliorates glioblastoma by disrupting mitochondrial oxidative phosphorylation and serine metabolism. iScience 104823 25 8 August 2022 | 35992092 |
208 | CALR | ARP30114_p050 | MAPRE1 as a plasma biomarker for early-stage colorectal cancer and adenomas. Cancer Prev Res (Phila). 26342024 | 26342024 |
209 | CASP1 | ARP58983_P050 | Tongxinluo May Alleviate Inflammation and Improve the Stability of Atherosclerotic Plaques by Changing the Intestinal Flora. Front Pharmacol 2022 NULL 13 805266 35431939 | 35431939 |
210 | CASP6 | OAAF05316 | Automating cell detection and classification in human brain fluorescent microscopy images using dictionary learning and sparse coding. J. Neurosci. Methods. 282, 20-33 (2017). 28267565 | 28267565 |
211 | CASP6 | OAAF05316 | Probing the correlation of neuronal loss, neurofibrillary tangles, and cell death markers across the Alzheimer's disease Braak stages: a quantitative study in humans. Neurobiol Aging. 61, 44531 (2018). 29031088 | 29031088 |
212 | CASPASE-3 | AVARP00021_T100 | A scaffold-free surface culture of B16F10 murine melanoma cells based on magnetic levitation. Cytotechnology. 68, 2323-2334 (2016). 27670438 | 27670438 |
213 | CAT | OAAB05216 | Identification and antioxidant activity of synthetic peptides from phycobiliproteins of Pyropia yezoensis. Int J Mol Med. 42, 789-798 (2018). 29717771 | 29717771 |
214 | CAT | OAAB05216 | PYP1-4 peptide from Pyropia yezoensis protects against acetaminophen-induced hepatotoxicity in HepG2 cells. Exp Ther Med. 19, 849-860 (2020). 32010245 | 32010245 |
215 | CATSPER2 | ARP35455_T100 | Kawano, N. et al. Seminal vesicle protein SVS2 is required for sperm survival in the uterus. Proc. Natl. Acad. Sci. U. S. A. 111, 4145-50 (2014). 24591616 | 24591616 |
216 | CAV2 | AVARP09020_P050 | Chi Sabins, N. et al. DLK1: a novel target for immunotherapeutic remodeling of the tumor blood vasculature. Mol. Ther. 21, 1958-68 (2013). 23896726 | 23896726 |
217 | CAV3 | OAAB03503 | Pavlović, D., McLatchie, L. M. & Shattock, M. J. The rate of loss of T-tubules in cultured adult ventricular myocytes is species dependent. Exp. Physiol. 95, 518-27 (2010). 20061354 | 20061354 |
218 | Cbln4 | ARP52505_P050 | Gupta, S. et al. Human organic cation transporter 1 is expressed in lymphoma cells and increases susceptibility to irinotecan and paclitaxel. J. Pharmacol. Exp. Ther. 341, 16-23 (2012). 22220752 | 22220752 |
219 | CBLN4 | ARP52505_P050 | Glycosylation of Cblns attenuates their receptor binding. Brain Res. 1694, 129-139 (2018) 29782851 | 29782851 |
220 | CBR1 | ARP45800_P050 | Lim, S. et al. Carbonyl reductase 1 is an essential regulator of skeletal muscle differentiation and regeneration. Int. J. Biochem. Cell Biol. 45, 1784-93 (2013). 23732109 | 23732109 |
221 | CBR1 | ARP45800_P050 | Mitani, T. et al. Resveratrol reduces the hypoxia-induced resistance to doxorubicin in breast cancer cells. J. Nutr. Sci. Vitaminol. (Tokyo). 60, 122-8 (2014). 24975222 | 24975222 |
222 | CBS | ARP45746_T100 | Fernandes, V. S. et al. Endogenous hydrogen sulfide has a powerful role in inhibitory neurotransmission to the pig bladder neck. J. Urol. 189, 1567-73 (2013). 23063804 | 23063804 |
223 | CBS | ARP45746_T100 | Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828 | 23103828 |
224 | CBS | ARP45746_T100 | Markand, S. et al. Cystathionine beta synthase expression in mouse retina. Curr. Eye Res. 38, 597-604 (2013). 23470016 | 23470016 |
225 | CBS | ARP45746_T100 | Dahlhoff, C. et al. Hepatic methionine homeostasis is conserved in C57BL/6N mice on high-fat diet despite major changes in hepatic one-carbon metabolism. PLoS One 8, e57387 (2013). 23472083 | 23472083 |
226 | CBS | ARP45746_T100 | Porteus, C. S. et al. The role of hydrogen sulphide in the control of breathing in hypoxic zebrafish (Danio rerio). J. Physiol. 592, 3075-88 (2014). 24756639 | 24756639 |
227 | CBS | ARP45746_T100 | Geillinger, K. E. et al. Hepatic metabolite profiles in mice with a suboptimal selenium status. J. Nutr. Biochem. 25, 914-22 (2014). 24917045 | 24917045 |
228 | CBS | ARP45746_T100 | Yamane, S., Kanno, T., Nakamura, H., Fujino, H. & Murayama, T. Hydrogen sulfide-mediated regulation of contractility in the mouse ileum with electrical stimulation: Roles of l-cysteine, cystathionine beta-synthase, and K(+) channels. Eur. J. Pharmacol. 740, 112-20 (2014). 25008073 | 25008073 |
229 | CBS | ARP45746_T100 | Dahlhoff, C. et al. Methyl-donor supplementation in obese mice prevents the progression of NAFLD, activates AMPK and decreases acyl-carnitine levels. Mol. Metab. 3, 565-80 (2014). 25061561 | 25061561 |
230 | CBX4 | ARP30002_P050 | Hao, L., Midic, U., Garriga, J. & Latham, K. E. Contribution of CBX4 to cumulus oophorus cell phenotype in mice and attendant effects in cumulus cell cloned embryos. Physiol. Genomics 46, 66-80 (2014). 24280258 | 24280258 |
231 | CCDC90A | ARP44777_P050 | Mitochondrial Ca2+ Uniporter haploinsufficiency enhances long-term potentiation at hippocampal mossy fibre synapses. J Cell Sci NULL NULL NULL October 2022 | 36274588 |
232 | CCL2 | AVARP07046_P050 | Key Players of Cisplatin Resistance: Towards a Systems Pharmacology Approach. Int J Mol Sci. 19, (2018). 29518977 | 29518977 |
233 | CCND3 | AVARP03038_P050 | Discovery of Human-Similar Gene Fusions in Canine Cancers. Cancer Res. 77, 5721-5727 (2017). 28883003 | 28883003 |
234 | CCR2 | OASA06081 | Bhangoo, S. et al. Delayed functional expression of neuronal chemokine receptors following focal nerve demyelination in the rat: a mechanism for the development of chronic sensitization of peripheral nociceptors. Mol. Pain 3, 38 (2007). 18076762 | 18076762 |
235 | CCR2 | OASA06081 | Bhangoo, S. K., Ripsch, M. S., Buchanan, D. J., Miller, R. J. & White, F. A. Increased chemokine signaling in a model of HIV1-associated peripheral neuropathy. Mol. Pain 5, 48 (2009). 19674450 | 19674450 |
236 | CCR2 | OASA06081 | Jeon, S.-M., Sung, J.-K. & Cho, H.-J. Expression of monocyte chemoattractant protein-1 and its induction by tumor necrosis factor receptor 1 in sensory neurons in the ventral rhizotomy model of neuropathic pain. Neuroscience 190, 354-66 (2011). 21712071 | 21712071 |
237 | CCT4 | ARP34271_P050 | Laux, A. et al. Localization of endogenous morphine-like compounds in the mouse spinal cord. J. Comp. Neurol. 520, 1547-61 (2012). 22133715 | 22133715 |
238 | CCT4 | ARP34271_P050 | Tarkar, A. et al. DYX1C1 is required for axonemal dynein assembly and ciliary motility. Nat. Genet. 45, 995-1003 (2013). 23872636 | 23872636 |
239 | CCT4 | ARP34271_P050 | Kdm3a lysine demethylase is an Hsp90 client required for cytoskeletal rearrangements during spermatogenesis. Mol Biol Cell. 25, 1216-33 (2014). 24554764 | 24554764 |
240 | CD117 | OAEE00057 | Expression of Luminal Progenitor Marker CD117 in the Human Breast Gland. J Histochem Cytochem. 66, 879-888 (2018). 30004288 | 30004288 |
241 | CD206 | OASA05048 | Lysosome associated membrane proteins maintain pancreatic acinar cell homeostasis: LAMP-2 deficient mice develop pancreatitis. Cell Mol Gastroenterol Hepatol. 1, 678-694 (2015). 26693174 | 26693174 |
242 | CD3 | OASA11552 | Natalizumab-associated progressive multifocal leukoencephalopathy in a patient with multiple sclerosis: a postmortem study. J Neuropathol Exp Neurol. 72, 1043-51 (2013). 24128680 | 24128680 |
243 | CD3 | OASA11552 | Lack of Major Histocompatibility Complex Class I Upregulation and Restrictive Infection by JC Virus Hamper Detection of Neurons by T Lymphocytes in the Central Nervous System. J Neuropathol Exp Neurol. 74, 791-803 (2015). 26115192 | 26115192 |
244 | CD34 | ARP60993_P050 | Telocytes in the hearts of Saanen goats. Microsc Res Tech 548-554 84 3 March 2021 | 33017500 |
245 | CD3G | OAAB01258 | A Novel CD3G Mutation in a Taiwanese Patient With Normal T Regulatory Function Presenting With the CVID Phenotype Free of Autoimmunity-Analysis of all Genotypes and Phenotypes. Front Immunol. 10, 2833 (2020). 31921117 | 31921117 |
246 | CD40LG | ARP33831_P050 | IFNT-independent effects of intrauterine extracellular vesicles (EVs) in cattle. Reproduction. 159, 503-511 (2020) 32103820 | 32103820 |
247 | CD68 | OABB00472 | Bmp signaling in colonic mesenchyme regulates stromal microenvironment and protects from polyposis initiation. Int J Cancer. 138, 2700-12 (2016). 26773796 | 26773796 |
248 | CD68 | OABB00472 | Cellular senescence drives age-dependent hepatic steatosis. Nat Commun. 8, 15691 (2017). 28608850 | 28608850 |
249 | CD68 | OABB00472 | Rapamycin improves healthspan but not inflammaging in nfκb1-/- mice. Aging Cell. 18, e12882 (2019). 30468013 | 30468013 |
250 | CD68 | OABB00472 | A Mitochondrial Specific Antioxidant Reverses Metabolic Dysfunction and Fatty Liver Induced by Maternal Cigarette Smoke in Mice. Nutrients. 11, (2019). 31330878 | 31330878 |
251 | CD68 | OABB00472 | FPR-1 is an important regulator of neutrophil recruitment and a tissue-specific driver of pulmonary fibrosis. JCI Insight. 5, (2020). 32102985 | 32102985 |
252 | CD68 | OABB00472 | c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis. Nat Metab. 2, 1350-1367 (2020) 33168981 | 33168981 |
253 | CD68 | OABB00472 | Moderate Exercise Inhibits Age-Related Inflammation, Liver Steatosis, Senescence, and Tumorigenesis. J Immunol. (2021). 33441438 | 33441438 |
254 | CD68 | OABB00472 | Moderate Exercise Inhibits Age-Related Inflammation, Liver Steatosis, Senescence, and Tumorigenesis. J Immunol. (2021). 31877385 | 31877385 |
255 | CDH5 | ARP60108_P050 | Wnt Site Signaling Inhibitor Secreted Frizzled-Related Protein 3 Protects Mitral Valve Endothelium From Myocardial Infarction-Induced Endothelial-to-Mesenchymal Transition. J Am Heart Assoc 2022 7 11 e023695 35348006 | 35348006 |
256 | CDK2 | ARP30331_P050 | The zebrafish miR-462/miR-731 cluster is induced under hypoxic stress via hypoxia-inducible factor 1a and functions in cellular adaptations. FASEB J. 29, 4901-13 (2015). 26265472 | 26265472 |
257 | CDKN1B | OAAI00157 | MYCN drives chemoresistance in small cell lung cancer while USP7 inhibition can restore chemosensitivity. Genes Dev. 34, 1210-1226 (2020) 32820040 | 32820040 |
258 | CDKN1B | OAEB01630 | Differential regulation of Janus kinase 3 (JAK3) in bovine preovulatory follicles and identification of JAK3 interacting proteins in granulosa cells. J Ovarian Res. 9, 71 (2016). 27793176 | 27793176 |
259 | CDX4 | ARP32765_P050 | Increased Cdx protein dose effects upon axial patterning in transgenic lines of mice. Development. 135, 2511-20 (2008). 18579683 | 18579683 |
260 | CEACAM6 | ARP41504_T100 | Kobayashi, M. et al. Carcinoembryonic antigen-related cell adhesion molecules as surrogate markers for EGFR inhibitor sensitivity in human lung adenocarcinoma. Br. J. Cancer 107, 1745-53 (2012). 23099808 | 23099808 |
261 | CEBPA | ARP57937_P050 | Borger, P. et al. Impaired translation of CCAAT/enhancer binding protein alpha mRNA in bronchial smooth muscle cells of asthmatic patients. J. Allergy Clin. Immunol. 123, 639-45 (2009). 19121862 | 19121862 |
262 | CEBPA | ARP57937_P050 | Miglino, N., Roth, M., Tamm, M. & Borger, P. House dust mite extract downregulates C/EBPa in asthmatic bronchial smooth muscle cells. Eur. Respir. J. 38, 50-8 (2011). 21109558 | 21109558 |
263 | CERS2 | ARP32609_P050 | Disrupted sphingolipid metabolism following acute clozapine and olanzapine administration. J Biomed Sci. 25, 40 (2018). 29720183 | 29720183 |
264 | CGI-58 | OAEB01343 | Skinner, J. R., Harris, L.-A. L. S., Shew, T. M., Abumrad, N. A. & Wolins, N. E. Perilipin 1 moves between the fat droplet and the endoplasmic reticulum. Adipocyte 2, 80-6 (2013). 23805403 | 23805403 |
265 | CHCHD3 | ARP57040_P050 | QIL1 mutation causes MICOS disassembly and early onset fatal mitochondrial encephalopathy with liver disease. Elife 2016 NULL 5 NULL 27623147 | 27623147 |
266 | CHML | OAAF04109 | Li, J. et al. Proteomic-based approach for biomarkers discovery in early detection of invasive urothelial carcinoma. Proteomics. Clin. Appl. 2, 78-89 (2008). 21136781 | 21136781 |
267 | CHST1 | ARP45495_T100 | Sulfation of O-glycans on Mucin-type Proteins From Serous Ovarian Epithelial Tumors. Mol Cell Proteomics. 20, 100150 (2021). 34555499 | 34555499 |
268 | CHST4 | ARP35787_T100 | Carbohydrate Sulfotransferase 4 Inhibits the Progression of Hepatitis B Virus-Related Hepatocellular Carcinoma and Is a Potential Prognostic Marker in Several Tumors. Front Oncol. 10, 554331 (2020). 33178582 | 33178582 |
269 | CK15 | AVARP00005_P050 | Celis, J. E. et al. 15-prostaglandin dehydrogenase expression alone or in combination with ACSM1 defines a subgroup of the apocrine molecular subtype of breast carcinoma. Mol. Cell. Proteomics 7, 1795-809 (2008). 18632593 | 18632593 |
270 | CKAP4 | ARP46790_P050 | Clark, R. et al. Comparative genomic and proteomic analysis of cytoskeletal changes in dexamethasone-treated trabecular meshwork cells. Mol. Cell. Proteomics 12, 194-206 (2013). 23105009 | 23105009 |
271 | CKMT2 | ARP41478_T100 | Choudhuri, A., Maitra, U. & Evans, T. Translation initiation factor eif3h targets specific transcripts to polysomes during embryogenesis. Proc. Natl. Acad. Sci. U. S. A. 110, 9818-23 (2013). 23716667 | 23716667 |
272 | CLCN3 | ARP35504_T100 | Jensen, V. K. et al. A quantitative assay for lysosomal acidification rates in human osteoclasts. Assay Drug Dev. Technol. 9, 157-64 (2011). 21050068 | 21050068 |
273 | CLDN1 | ARP33623_P050 | Inhibition of Single Routes of Intracellular Signaling is Not Sufficient to Neutralize the Biphasic Disturbance of a Retinal Endothelial Cell Barrier Induced by VEGF-A165. Cell Physiol Biochem 1493-1513 42 4 July 2017 | 28719888 |
274 | CLIC1 | ARP35045_T100 | Yang, J.-Y. et al. Chloride intracellular channel 1 regulates osteoblast differentiation. Bone 45, 1175-85 (2009). 19703605 | 19703605 |
275 | CLIC5 | ARP35262_T100 | Li, F.-N. et al. Chloride intracellular channel 5 modulates adipocyte accumulation in skeletal muscle by inhibiting preadipocyte differentiation. J. Cell. Biochem. 110, 1013-21 (2010). 20564201 | 20564201 |
276 | CLIC5 | ARP35263_P050 | The chloride intracellular channel 5A stimulates podocyte Rac1, protecting against hypertension-induced glomerular injury. Kidney Int. 89, 833-47 (2016). 26924049 | 26924049 |
277 | CLIC5 | ARP35263_T100 | Both CLIC4 and CLIC5A activate ERM proteins in glomerular endothelium. Am. J. Physiol. Renal Physiol. 311, F945-F957 (2016). 27582103 | 27582103 |
278 | CLU | ARP61142_P050 | Clusterin secretion is attenuated by the proinflammatory cytokines interleukin-1β and tumor necrosis factor-α in models of cartilage degradation. J Orthop Res. (2020) 32725904 | 32725904 |
279 | CLUH | ARP70642_P050 | Clueless/CLUH regulates mitochondrial fission by promoting recruitment of Drp1 to mitochondria. Nat Commun 2022 1 13 1582 35332133 | 35332133 |
280 | CLUH | ARP70642_P050 | CLUH controls astrin-1 expression to couple mitochondrial metabolism to cell cycle progression. Elife 2022 NULL 11 NULL 35559794 | 35559794 |
281 | CNOT7 | ARP39026_P050 | Maragozidis, P. et al. Alterations of deadenylase expression in acute leukemias: evidence for poly(a)-specific ribonuclease as a potential biomarker. Acta Haematol. 128, 39-46 (2012). 22614729 | 22614729 |
282 | COL1A1 | OAAB10798 | Discoidin domain receptor 1 activation links extracellular matrix to podocyte lipotoxicity in Alport syndrome. EBioMedicine. 63, 103162 (2020). 33340991 | 33340991 |
283 | COL1A1 | OAAB10798 | Endoplasmic reticulum protein TXNDC5 promotes renal fibrosis by enforcing TGF-β signaling in kidney fibroblasts. J Clin Invest. 131 (2021). 33465051 | 33465051 |
284 | COL1A2 | OAAF01757 | Insulin receptor substrate-1 time-dependently regulates bone formation by controlling collagen Iα2 expression via miR-342. FASEB J. 30, 4214-4226 (2016). 27623927 | 27623927 |
285 | COL1A2 | OAAF02899 | Insulin receptor substrate-1 time-dependently regulates bone formation by controlling collagen Ia2 expression via miR-342. FASEB J. 30, 4214-4226 (2016). 27623927 | 27623927 |
286 | COL6A3 | OAAF02910 | Isolation and characterisation of a novel trophoblast side-population from first trimester placentae. Reproduction. 150, 449-62 (2015). 26248480 | 26248480 |
287 | Collagen I | OPED00033 | CNS fibroblasts form a fibrotic scar in response to immune cell infiltration. Nat Neurosci 2021 2 24 234-244 33526922 | 33526922 |
288 | Collagen Type I | OAMA03716 | Novel high-throughput myofibroblast assays identify agonists with therapeutic potential in pulmonary fibrosis that act via EP2 and EP4 receptors. PLoS One. 13, e0207872 (2018). 30485339 | 30485339 |
289 | Collagen Type I | OAMA03716 | GPCR-induced YAP activation sensitizes fibroblasts to profibrotic activity of TGFβ1. PLoS One. 15, e0228195 (2020). 32053631 | 32053631 |
290 | COX15 | ARP46442_T100 | Analysis of Oligomerization Properties of Heme a Synthase Provides Insights into Its Function in Eukaryotes. J. Biol. Chem. 291, 10411-25 (2016). 26940873 | 26940873 |
291 | COX4I1 | ARP42784_T100 | Snyder, A. M. et al. Mitochondrial ferritin in the substantia nigra in restless legs syndrome. J. Neuropathol. Exp. Neurol. 68, 1193-9 (2009). 19816198 | 19816198 |
292 | COX4l1 | ARP42784_T100 | Geerling, J. J. et al. Metformin lowers plasma triglycerides by promoting VLDL-triglyceride clearance by brown adipose tissue in mice. Diabetes 63, 880-91 (2014). 24270984 | 24270984 |
293 | CPR | ARP44362_P050 | Lee, J. W., Kim, Y. H., Yoon, S. & Lee, S. K. Cytochrome P450 system expression and DNA adduct formation in the liver of Zacco platypus following waterborne Benzo(a)pyrene exposure: implications for biomarker determination. Environ. Toxicol. (2012). doi:10.1002/tox.21833 23192953 | 23192953 |
294 | CPT1 | ARP44796_P050 | Laghezza, A. et al. New 2-(aryloxy)-3-phenylpropanoic acids as peroxisome proliferator-activated receptor a/γ dual agonists able to upregulate mitochondrial carnitine shuttle system gene expression. J. Med. Chem. 56, 60-72 (2013). 23171045 | 23171045 |
295 | CPT1A | ARP44796_P050 | The contribution of the citrate pathway to oxidative stress in Down syndrome. Immunology. 149, 423-431 (2016). 27502741 | 27502741 |
296 | CPT1A | ARP44796_P050 | New diphenylmethane derivatives as peroxisome proliferator-activated receptor alpha/gamma dual agonists endowed with anti-proliferative effects and mitochondrial activity. Eur J Med Chem. 127, 379-397 (2017). 28076827 | 28076827 |
297 | CPT1A | ARP44796_P050 | Silibinin improves nonalcoholic fatty liver by regulating the expression of miR‑122: An in vitro and in vivo study. Mol Med Rep. 23 (2021) 33760189 | 33760189 |
298 | CPT1A | ARP44796_P050 | The role of CD36-Fabp4-PPARγ in skeletal muscle involves insulin resistance in intrauterine growth retardation mice with catch-up growth. BMC Endocr Disord. 22, 10 (2022). 34983495 | 34983495 |
299 | CPT1B | ARP46444_P050 | Wolf-Johnston, A. S. et al. Alterations in the non-neuronal acetylcholine synthesis and release machinery in esophageal epithelium. Life Sci. 91, 1065-9 (2012). 22569297 | 22569297 |
300 | CPT1B | ARP46444_P050 | Effects of neonatal dexamethasone administration on cardiac recovery ability under ischemia-reperfusion in 24-wk-old rats. Pediatr. Res. 80, 128-35 (2016). 26991264 | 26991264 |
301 | CPT1B | ARP46444_P050 | Enhancement of Glucose Metabolism via PGC-1a Participates in the Cardioprotection of Chronic Intermittent Hypobaric Hypoxia. Front Physiol. 7, 219 (2016). 27375497 | 27375497 |
302 | CPT2 | OAAN00972 | Reduced mitochondrial translation prevents diet-induced metabolic dysfunction but not inflammation. Aging (Albany NY). 12, 19677-19700 (2020). 33024056 | 33024056 |
303 | CPT2 | OAAN00972 | A common genetic variant of a mitochondrial RNA processing enzyme predisposes to insulin resistance. Sci Adv. 7, eabi7514 (2021). 34559558 | 34559558 |
304 | CREB3L2 | ARP34673_T100 | Sievert, A. J. et al. Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene. Brain Pathol. 19, 449-58 (2009). 19016743 | 19016743 |
305 | CREB3L2 | ARP34673_T100 | Fox, R. M., Hanlon, C. D. & Andrew, D. J. The CrebA/Creb3-like transcription factors are major and direct regulators of secretory capacity. J. Cell Biol. 191, 479-92 (2010). 21041443 | 21041443 |
306 | CREB3L2 | ARP34673_T100 | Lynch, J. M. et al. A thrombospondin-dependent pathway for a protective ER stress response. Cell 149, 1257-68 (2012). 22682248 | 22682248 |
307 | CREB3L2 | ARP34673_T100 | CREB3L1-mediated functional and structural adaptation of the secretory pathway in hormone-stimulated thyroid cells. J Cell Sci. 130, 4155-4167 (2017). 29093023 | 29093023 |
308 | CREBBP | ARP43609_P050 | p300 Serine 89: A Critical Signaling Integrator and Its Effects on Intestinal Homeostasis and Repair. Cancers (Basel). 13 (2021). 33799418 | 33799418 |
309 | CREBBP | ARP43609_P050 | p300 Serine 89: A Critical Signaling Integrator and Its Effects on Intestinal Homeostasis and Repair. Cancers (Basel). 13 (2021). 34884992 | 34884992 |
310 | CRHR1 | OASG01837 | Somatostatin receptor subtype 5 modifies hypothalamic-pituitary-adrenal axis stress function. JCI Insight. 3, (2018). 30282821 | 30282821 |
311 | CRHR1 | OASG01837 | Orexin A Enhances Pro-Opiomelanocortin Transcription Regulated by BMP-4 in Mouse Corticotrope AtT20 Cells. Int J Mol Sci. 22 (2021) 33925368 | 33925368 |
312 | CRY1 | ARP59758_P050 | Deep-brain photoreception links luminance detection to motor output in Xenopus frog tadpoles. Proc. Natl. Acad. Sci. U.S.A. 113, 6053-8 (2016). 27166423 | 27166423 |
313 | CRY2 | ARP52398_P050 | Deep-brain photoreception links luminance detection to motor output in Xenopus frog tadpoles. Proc. Natl. Acad. Sci. U.S.A. 113, 6053-8 (2016). 27166423 | 27166423 |
314 | CSE | ARP31932_P050 | Fernandes, V. S. et al. Endogenous hydrogen sulfide has a powerful role in inhibitory neurotransmission to the pig bladder neck. J. Urol. 189, 1567-73 (2013). 23063804 | 23063804 |
315 | CSF1R | OAAB18690 | Inhaled Seralutinib Exhibits Potent Efficacy in Models of Pulmonary Arterial Hypertension. Eur Respir J 2022 NULL NULL NULL 35680144 | 35680144 |
316 | CSN1S1 | OAAB03556 | Pick, E. et al. The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain. PLoS One 7, e43980 (2012). 22956996 | 22956996 |
317 | CSN2 | ARP38431_T100 | Pick, E. et al. The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain. PLoS One 7, e43980 (2012). 22956996 | 22956996 |
318 | CSN8 | ARP52242_P050 | Pick, E. et al. The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain. PLoS One 7, e43980 (2012). 22956996 | 22956996 |
319 | CXCL12 | OAAB09710 | de Paz, J. L. et al. Profiling heparin-chemokine interactions using synthetic tools. ACS Chem. Biol. 2, 735-44 (2007). 18030990 | 18030990 |
320 | CXCL14 | AVARP07023_P050 | Takahashi, M. et al. CXCL14 enhances insulin-dependent glucose uptake in adipocytes and is related to high-fat diet-induced obesity. Biochem. Biophys. Res. Commun. 364, 1037-42 (2007). 17971304 | 17971304 |
321 | CXCL14 | AVARP07023_P050 | Lietz, R. et al. Codelivery of the chemokine CCL3 by an adenovirus-based vaccine improves protection from retrovirus infection. J. Virol. 86, 1706-16 (2012). 22090142 | 22090142 |
322 | CXCL14 | AVARP07023_P050 | Perrone, C. E. et al. Genomic and metabolic responses to methionine-restricted and methionine-restricted, cysteine-supplemented diets in Fischer 344 rat inguinal adipose tissue, liver and quadriceps muscle. J. Nutrigenet. Nutrigenomics 5, 132-57 (2012). 23052097 | 23052097 |
323 | CXCL9 | OAAB02538 | Markosyan, N. et al. Mammary Carcinoma Cell Derived Cyclooxygenase 2 Suppresses Tumor Immune Surveillance by Enhancing Intratumoral Immune Checkpoint Activity. Breast Cancer Res. 15, R75 (2013). 24004819 | 24004819 |
324 | CXCR4 | ARP30799_P050 | Biopolymer-delivered vascular endothelial growth factor improves renal outcomes following revascularization. Am J Physiol Renal Physiol. 316, F1016-F1025 (2019). 30892933 | 30892933 |
325 | CYBB | OABB00620 | Different signalling in infarcted and non-infarcted areas of rat failing hearts: A role of necroptosis and inflammation. J Cell Mol Med. 23, 6429-6441 (2019). 31328381 | 31328381 |
326 | CYP19A1 | OASA02666 | Tezak, B., I. Romero, S. Milton and J. Wyneken. Identifying Sex of Neonate Turtles with Temperature-dependent Sex Determination via Small Blood Samples. Sci Rep. 2020; 10: 5012. 32193464 | 32193464 |
327 | CYP21A2 | ARP60144_P050 | Pregnancy-associated changes of peroxisome proliferator-activated receptor delta (PPARD) and cytochrome P450 family 21 subfamily A member 2 (CYP21A2) expression in the bovine corpus luteum. J Reprod Dev. 66, 205-213 (2020). 32037375 | 32037375 |
328 | CYP24A1 | OABB02030 | Hiroki Maruyama, et al. Low bone mineral density due to secondary hyperparathyroidism in the GlatmTg(CAG-A4GALT) mouse model of Fabry disease. 365-381 (2020). 32617522 | 32617522 |
329 | CYP26B1 | ARP57351_P050 | Targeting HOTAIRM1 ameliorates glioblastoma by disrupting mitochondrial oxidative phosphorylation and serine metabolism. iScience 104823 25 8 August 2022 | 35992092 |
330 | DAGLA | OAEB01139 | Phosphoproteomic Analysis of Subcutaneous and Omental Adipose Tissue Reveals Increased Lipid Turnover in Dairy Cows Supplemented with Conjugated Linoleic Acid. Int J Mol Sci. 22 (2021). 33810070 | 33810070 |
331 | DAZAP1 | ARP41161_P050 | Hayakawa, H. et al. Human proteins that specifically bind to 8-oxoguanine-containing RNA and their responses to oxidative stress. Biochem. Biophys. Res. Commun. 403, 220-4 (2010). 21073862 | 21073862 |
332 | DBP | ARP31587_P050 | Alterations of Hepatic Metabolism in Chronic Kidney Disease via D-box-binding Protein Aggravate the Renal Dysfunction. J. Biol. Chem. 291, 4913-27 (2016). 26728457 | 26728457 |
333 | DBP | ARP31587_P050 | Clock Gene Dysregulation Induced by Chronic ER Stress Disrupts b-cell Function. EBioMedicine. (2017). 28389215 | 28389215 |
334 | DBP | ARP32195_P050 | Nakabayashi, H. et al. Clock-controlled output gene Dbp is a regulator of Arnt/Hif-1beta gene expression in pancreatic islet beta-cells. Biochem. Biophys. Res. Commun. 434, 370-5 (2013). 23567972 | 23567972 |
335 | DBP | ARP32195_P050 | Okazaki, H. et al. Circadian regulation of mTOR by the ubiquitin pathway in renal cell carcinoma. Cancer Res. 74, 543-51 (2014). 24253377 | 24253377 |
336 | DBP | ARP32195_P050 | Low-Grade Inflammation Aggravates Rotenone Neurotoxicity and Disrupts Circadian Clock Gene Expression in Rats. Neurotox Res. 35, 421-431 (2019). 30328585 | 30328585 |
337 | DCST1 | ARP43421_P050 | Dong, R. et al. Cells with dendritic cell morphology and immunophenotype, binuclear morphology, and immunosuppressive function in dendritic cell cultures. Cell. Immunol. 272, 1-10 (2011). 22030471 | 22030471 |
338 | DDIT3 | ARP31591_P050 | Sex Hormone Binding Globulin (SHBG) Mitigates ER Stress in Hepatocytes In Vitro and Ex Vivo. Cells 2021 4 10 NULL 33808055 | 33808055 |
339 | DEK | OAAB05777 | Clawson, G. A., Bui, V., Xin, P., Wang, N. & Pan, W. Intracellular localization of the tumor suppressor HtrA1/Prss11 and its association with HPV16 E6 and E7 proteins. J. Cell. Biochem. 105, 81-8 (2008). 18452160 | 18452160 |
340 | DEK | OAAB05777 | Privette Vinnedge, L. M. et al. The human DEK oncogene stimulates beta-catenin signaling, invasion and mammosphere formation in breast cancer. Oncogene 30, 2741-52 (2011). 21317931 | 21317931 |
341 | DGCR8 | ARP40984_P050 | Kye, M. J. et al. NMDA mediated contextual conditioning changes miRNA expression. PLoS One 6, e24682 (2011). 21931811 | 21931811 |
342 | DGCR8 | ARP40984_P050 | Van Duyne, R. et al. Localization and sub-cellular shuttling of HTLV-1 tax with the miRNA machinery. PLoS One 7, e40662 (2012). 22808228 | 22808228 |
343 | DGCR8 | ARP40984_P050 | DGCR8 is essential for tumor progression following PTEN loss in the prostate. EMBO Rep. 16, 1219-32 (2015). 26206718 | 26206718 |
344 | DHX34 | ARP36417_P050 | Histamine receptors mediate contraction of reticular groove smooth muscle of adult goats. Anat Histol Embryol 440-450 49 4 July 2020 | 32128873 |
345 | DHX9 | ARP36343_P050 | Kawai, S. & Amano, A. BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex. J. Cell Biol. 197, 201-8 (2012). 22492723 | 22492723 |
346 | DLL1 | ARP46625_P050 | Suprynowicz, F. A. et al. Conditionally reprogrammed cells represent a stem-like state of adult epithelial cells. Proc. Natl. Acad. Sci. U. S. A. 109, 20035-40 (2012). 23169653 | 23169653 |
347 | DLL1 | ARP46625_P050 | Caliceti, C. et al. 17beta-estradiol enhances signalling mediated by VEGF-A-delta-like ligand 4-notch1 axis in human endothelial cells. PLoS One 8, e71440 (2013). 23967210 | 23967210 |
348 | DMBT1 | ARP42352_P050 | Induction of the endogenous sialoglycan ligand for eosinophil death receptor Siglec-8 in chronic rhinosinusitis with hyperplastic nasal polyposis. Glycobiology 2021 8 31 1026-1036 33755113 | 33755113 |
349 | DMP-1 | ARP34602_P050 | Tooth Germ-Like Construct Transplantation for Whole-Tooth Regeneration: An In Vivo Study in the Miniature Pig. Artif Organs. 40, E39-50 (2016). 26582651 | 26582651 |
350 | DNM1L | ARP52329_P050 | Su, Y. C., Chiu, H. W., Hung, J. C. & Hong, J. R. Beta-nodavirus B2 protein induces hydrogen peroxide production, leading to Drp1-recruited mitochondrial fragmentation and cell death via mitochondrial targeting. Apoptosis 19, 1457-70 (2014). 25008790 | 25008790 |
351 | DPP10 | OAAB05596 | Manipulation of dipeptidylpeptidase 10 in mouse and human in vivo and in vitro models indicates a protective role in asthma. Dis Model Mech. 11, (2018). 29361513 | 29361513 |
352 | DPP4 | ARP63319_P050 | Upregulated expression and activation of membrane‑associated proteases in esophageal squamous cell carcinoma. Oncol Rep. 31, 2820-6 (2014). 24789592 | 24789592 |
353 | DSCAM | ARP45086_P050 | DSCAM is differentially patterned along the optic axon pathway in the developing Xenopus visual system and guides axon termination at the target. Neural Dev 2022 1 17 5 35422013 | 35422013 |
354 | DSG2 | ARP45198_P050 | Hummitzsch, K. et al. A new model of development of the mammalian ovary and follicles. PLoS One 8, e55578 (2013). 23409002 | 23409002 |
355 | DTX1 | OAGA00965 | Glycogen synthase kinase 3β inhibition enhances Notch1 recycling. Mol Biol Cell. 29, 389-395 (2018). 29237816 | 29237816 |
356 | DTX1 | OAGA00965 | PI5P4Kγ functions in DTX1-mediated Notch signaling. Proc Natl Acad Sci U S A. 115, E1983-E1990 (2018). 29440432 | 29440432 |
357 | EAAT2 | ARP33840_P050 | Pretto, D. I. et al. Reduced excitatory amino acid transporter 1 and metabotropic glutamate receptor 5 expression in the cerebellum of fragile X mental retardation gene 1 premutation carriers with fragile X-associated tremor/ataxia syndrome. Neurobiol. Aging 35, 1189-97 (2014). 24332449 | 24332449 |
358 | EDA | OAAB03423 | a de novo 3.8-Mb inversion affecting the EDA and XIST genes in a heterozygous female calf with generalized hypohidrotic ectodermal dysplasia. BMC Genomics. 20, 715 (2019). 31533624 | 31533624 |
359 | EDEM1 | ARP47054_P050 | ERADication of EDEM1 occurs by selective autophagy and requires deglycosylation by cytoplasmic peptide N-glycanase. Histochem Cell Biol 2014 2 142 153-69 24664425 | 24664425 |
360 | EDF1 | ARP37729_T100 | Vitamin D Prevents High Glucose-Induced Lipid Droplets Accumulation in Cultured Endothelial Cells: The Role of Thioredoxin Interacting Protein. Biomedicines 2021 12 9 NULL 34944690 | 34944690 |
361 | EEA1 | ARP30074_P050 | Rab22a controls MHC-I intracellular trafficking and antigen cross-presentation by dendritic cells. EMBO Rep. 17, 1753-1765 (2016). 27861124 | 27861124 |
362 | EEF2 | ARP58457_P050 | Chaperone Function of Hgh1 in the Biogenesis of Eukaryotic Elongation Factor 2. Mol Cell. 74, 88-100.e9 (2019). 30876804 | 30876804 |
363 | EFNB3 | OAAF01784 | Estrogen and testosterone in concert with EFNB3 regulate vascular smooth muscle cell contractility and blood pressure. Am J Physiol Heart Circ Physiol. 310, H861-72 (2016). 26851246 | 26851246 |
364 | EGR1 | ARP32241_P050 | Barbolina, M. V, Adley, B. P., Ariztia, E. V, Liu, Y. & Stack, M. S. Microenvironmental regulation of membrane type 1 matrix metalloproteinase activity in ovarian carcinoma cells via collagen-induced EGR1 expression. J. Biol. Chem. 282, 4924-31 (2007). 17158885 | 17158885 |
365 | EGR1 | ARP32241_P050 | Wenzel, K. et al. Expression of the protein phosphatase 1 inhibitor KEPI is downregulated in breast cancer cell lines and tissues and involved in the regulation of the tumor suppressor EGR1 via the MEK-ERK pathway. Biol. Chem. 388, 489-95 (2007). 17516844 | 17516844 |
366 | EGR1 | ARP32241_P050 | Jaluria, P., Konstantopoulos, K., Betenbaugh, M. & Shiloach, J. Egr1 and Gas6 facilitate the adaptation of HEK-293 cells to serum-free media by conferring enhanced viability and higher growth rates. Biotechnol. Bioeng. 99, 1443-52 (2008). 18023050 | 18023050 |
367 | EGR1 | ARP32241_P050 | Tennis, M. A. et al. Prostacyclin inhibits non-small cell lung cancer growth by a frizzled 9-dependent pathway that is blocked by secreted frizzled-related protein 1. Neoplasia 12, 244-53 (2010). 20368707 | 20368707 |
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370 | EGR1 | ARP32241_P050 | Temporal Analysis of Gene Expression in the Murine Schwann Cell Lineage and the Acutely Injured Postnatal Nerve. PLoS ONE. 11, e0153256 (2016). 27058953 | 27058953 |
371 | EGR2 | P100880_P050 | Latasa, M.-J., Ituero, M., Moran-Gonzalez, A., Aranda, A. & Cosgaya, J. M. Retinoic acid regulates myelin formation in the peripheral nervous system. Glia 58, 1451-64 (2010). 20648638 | 20648638 |
372 | EGR2 | P100880_P050 | Lagrange, B. et al. A role for miR-142-3p in colony-stimulating factor 1-induced monocyte differentiation into macrophages. Biochim. Biophys. Acta 1833, 1936-46 (2013). 23602969 | 23602969 |
373 | EGR2 | P100880_P050 | Damm, F. et al. Acquired initiating mutations in early hematopoietic cells of CLL patients. Cancer Discov. 4, 1088-101 (2014). 24920063 | 24920063 |
374 | EHF | ARP40136_P050 | He, J. et al. Profile of Ets gene expression in human breast carcinoma. Cancer Biol. Ther. 6, 76-82 (2007). 17172821 | 17172821 |
375 | EIF2A | ARP41041_T100 | Xu, Y.-X., Liu, L., Caffaro, C. E. & Hirschberg, C. B. Inhibition of Golgi apparatus glycosylation causes endoplasmic reticulum stress and decreased protein synthesis. J. Biol. Chem. 285, 24600-8 (2010). 20529871 | 20529871 |
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377 | EIF3M | ARP48293_T100 | Cheshenko, N., Trepanier, J. B., Segarra, T. J., Fuller, A. O. & Herold, B. C. HSV usurps eukaryotic initiation factor 3 subunit M for viral protein translation: novel prevention target. PLoS One 5, e11829 (2010). 20676407 | 20676407 |
378 | ELF3 | ARP36846_P050 | Namiki, T., Valencia, J. C., Hall, M. D. & Hearing, V. J. A novel approach to enhance antibody sensitivity and specificity by peptide cross-linking. Anal. Biochem. 383, 265-9 (2008). 18801330 | 18801330 |
379 | ELOVL6 | ARP64566_P050 | Transcriptional regulation of bovine elongation of very long chain fatty acids protein 6 in lipid metabolism and adipocyte proliferation. J Cell Biochem 13932-13943 120 8 August 2019 | 30945346 |
380 | EMC6 | OACA03845 | Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry. Nat Commun. 11, 1127 (2020). 32111841 | 32111841 |
381 | EMG1 | ARP40636_P050 | Armistead, J. et al. Mutation of a gene essential for ribosome biogenesis, EMG1, causes Bowen-Conradi syndrome. Am. J. Hum. Genet. 84, 728-39 (2009). 19463982 | 19463982 |
382 | ENO1 | ARP34376_T100 | Rambaruth, N. D. S., Greenwell, P. & Dwek, M. V. The lectin Helix pomatia agglutinin recognizes O-GlcNAc containing glycoproteins in human breast cancer. Glycobiology 22, 839-48 (2012). 22322011 | 22322011 |
383 | ENO1 | ARP34377_P050 | Boraldi, F. et al. Hypoxia influences the cellular cross-talk of human dermal fibroblasts. A proteomic approach. Biochim. Biophys. Acta 1774, 1402-13 (2007). 17904921 | 17904921 |
384 | ENO1 | ARP34377_P050 | Sørensen, B. S. et al. Proteins upregulated by mild and severe hypoxia in squamous cell carcinomas in vitro identified by proteomics. Radiother. Oncol. 92, 443-9 (2009). 19541378 | 19541378 |
385 | ENO1 | ARP34377_P050 | Deng, M. Y. et al. Frontal-subcortical protein expression following prenatal exposure to maternal inflammation. PLoS One 6, e16638 (2011). 21347362 | 21347362 |
386 | ENO1 | ARP34377_P050 | Kitahashi, T., Yoshimoto, M. & Imai, T. Novel immunohistochemical marker, integrin a(V)beta(3), for BOP-induced early lesions in hamster pancreatic ductal carcinogenesis. Oncol. Lett. 2, 229-234 (2011). 22866069 | 22866069 |
387 | ENO1 | ARP34377_P050 | Braceland, M. et al. Serum enolase: a non-destructive biomarker of white skeletal myopathy during pancreas disease (PD) in Atlantic salmon Salmo salar L. J. Fish Dis. doi:10.1111/jfd.12296 (2014). 25168106 | 25168106 |
388 | ENO3 | ARP48203_T100 | Chaika, N. V et al. Differential expression of metabolic genes in tumor and stromal components of primary and metastatic loci in pancreatic adenocarcinoma. PLoS One 7, e32996 (2012). 22412968 | 22412968 |
389 | ENPP1 | OAEB02445 | de la Croix Ndong, J. et al. Asfotase-a improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1. Nat. Med. 20, 904-10 (2014). 24997609 | 24997609 |
390 | EP300 | OAAF01891 | Differential Kat3 Usage Orchestrates the Integration of Cellular Metabolism with Differentiation. Cancers (Basel). 13 (2021). 34884992 | 34884992 |
391 | EPAS1 | ARP32253_P050 | Human placental renin-angiotensin system in normotensive and pre-eclamptic pregnancies at high altitude and after acute hypoxia-reoxygenation insult. J Physiol 2016 5 594 1327-40 26574162 | 26574162 |
392 | EPAS1 | ARP32253_P050 | HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice. Nat Commun 2020 1 11 4111 32807776 | 32807776 |
393 | EPB41L3 | OAGA01718 | Tumor-derived Autoantibodies Identify Malignant Pulmonary Nodules. Am J Respir Crit Care Med. 199, 1257-1266 (2019). 30422669 | 30422669 |
394 | EPHRIN B1 | OAAF00520 | Activating Mutations in PIK3CA Lead to Widespread Modulation of the Tyrosine Phosphoproteome. J. Proteome Res. 14, 3882-91 (2015). 26267517 | 26267517 |
395 | ERP29 | ARP44820_P050 | Protein disulfide isomerase secretion following vascular injury initiates a regulatory pathway for thrombus formation. Nat Commun. 8, 14151 (2017). 28218242 | 28218242 |
396 | Esr2 | ARP37039_P050 | The conserved sex regulator DMRT1 recruits SOX9 in sexual cell fate reprogramming. Nucleic Acids Res 2021 11 49 6144-6164 34096593 | 34096593 |
397 | ESRRG | ARP31655_T100 | Song, G. & Wang, L. Transcriptional mechanism for the paired miR-433 and miR-127 genes by nuclear receptors SHP and ERRgamma. Nucleic Acids Res. 36, 5727-35 (2008). 18776219 | 18776219 |
398 | ESRRG | ARP31655_T100 | Song, G. & Wang, L. A conserved gene structure and expression regulation of miR-433 and miR-127 in mammals. PLoS One 4, e7829 (2009). 19946636 | 19946636 |
399 | ETS1 | P100604_T100 | ETS1 induction by the microenvironment promotes ovarian cancer metastasis through focal adhesion kinase. Cancer Lett. 414, 190-204 (2018). 29174800 | 29174800 |
400 | ETS2 | OAAB06446 | Yoshimatsu, Y. et al. Ets family members induce lymphangiogenesis through physical and functional interaction with Prox1. J. Cell Sci. 124, 2753-62 (2011). 21807940 | 21807940 |
401 | EXT2 | ARP44277_P050 | Oocyte Cytoplasmic Gas6 and Heparan Sulfate (HS) are Required to Establish the Open Chromatin State in Nuclei During Remodeling and Reprogramming. Cell Physiol Biochem. 45, 37-53 (2018). 29316553 | 29316553 |
402 | EYA1 | ARP32434_P050 | The Eya1 phosphatase promotes Shh signaling during hindbrain development and oncogenesis. Dev Cell. 33, 22-35 (2015). 25816987 | 25816987 |
403 | F2 | ARP41757_P050 | Vascular Endothelial Cells Produce Coagulation Factors That Control Their Growth via Joint Protease-Activated Receptor and C5a Receptor 1 (CD88) Signaling. Am J Pathol 2022 2 192 361-378 35144762 | 35144762 |
404 | Fa2h | ARP33121_P050 | Effects of Environmental Heat Load on Endocannabinoid System Components in Adipose Tissue of High Yielding Dairy Cows. Animals (Basel) NULL 12 6 March 2022 | 35327191 |
405 | FABP3 | ARP33823_T100 | Chen, H.-M., Zheng, C.-X., Gao, Q., Ge, Y.-C. & Liu, Z.-H. Heart-type fatty acid binding protein is associated with proteinuria in obesity. PLoS One 7, e45691 (2012). 23029183 | 23029183 |
406 | FAH | ARP41681_T100 | Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 | 24465277 |
407 | FAH | ARP41681_T100 | Functional and Biochemical Characterization of Hepatitis C Virus (HCV) Particles Produced in a Humanized Liver Mouse Model. J. Biol. Chem. 290, 23173-87 (2015). 26224633 | 26224633 |
408 | FAM123B | OAAB03558 | Exome Sequencing Reveals AMER1 as a Frequently Mutated Gene in Colorectal Cancer. Clin Cancer Res. 21, 4709-18 (2015). 26071483 | 26071483 |
409 | FAM20A | OACD03385 | Lack of FAM20A, Ectopic Gingival Mineralization and Chondro/Osteogenic Modifications in Enamel Renal Syndrome. Front Cell Dev Biol. 8, 605084 (2021). 33425910 | 33425910 |
410 | FAM20A | OACD03385 | Pathogenesis of Enamel-Renal Syndrome Associated Gingival Fibromatosis: A Proteomic Approach. Front Endocrinol (Lausanne). 12, 752568 (2021). 34777248 | 34777248 |
411 | FAM20A | OACD03385 | Enamel and dentin in Enamel renal syndrome: A confocal Raman microscopy view. Front Physiol 957110 13 NULL September 2022 | 36091358 |
412 | FAM20C | OAAB01003 | Lack of FAM20A, Ectopic Gingival Mineralization and Chondro/Osteogenic Modifications in Enamel Renal Syndrome. Front Cell Dev Biol. 8, 605084 (2021). 33425910 | 33425910 |
413 | FAM20C | OAAB01003 | Enamel and dentin in Enamel renal syndrome: A confocal Raman microscopy view. Front Physiol 957110 13 NULL September 2022 | 36091358 |
414 | FAM40B | OAAB02551 | Carbonic Anhydrase 8 Expression in Purkinje Cells Is Controlled by PKCγ Activity and Regulates Purkinje Cell Dendritic Growth. Mol Neurobiol 2016 8 53 5149-60 26399641 | 26399641 |
415 | FASTK | OAAB08734 | Bauer, A. et al. Identification of malignancy factors by analyzing cystic tumors of the pancreas. Pancreatology 9, 34-44 (2009). 19077453 | 19077453 |
416 | FBL | ARP40366_T100 | Ernoult-Lange, M. et al. Nucleocytoplasmic traffic of CPEB1 and accumulation in Crm1 nucleolar bodies. Mol. Biol. Cell 20, 176-87 (2009). 18923137 | 18923137 |
417 | FBL | ARP40366_T100 | Armistead, J. et al. Mutation of a gene essential for ribosome biogenesis, EMG1, causes Bowen-Conradi syndrome. Am. J. Hum. Genet. 84, 728-39 (2009). 19463982 | 19463982 |
418 | FBP1 | ARP41406_T100 | Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 | 24465277 |
419 | FBXL2 | OAAB02444 | Crystal structure and interaction studies of the human FBxo3 ApaG domain. FEBS J. 283, 2091-101 (2016). 27010866 | 27010866 |
420 | FBXO7 | ARP43128_P050 | The E3 ubiquitin ligase SCF(Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-κB signaling pathway. Biochim Biophys Acta Gen Subj 2021 1 1865 129754 33010352 | 33010352 |
421 | Fbxw7 | ARP37443_P050 | Huang, H. et al. NF-κB1 inhibits c-Myc protein degradation through suppression of FBW7 expression. Oncotarget 5, 493-505 (2014). 24457827 | 24457827 |
422 | FBXW7 | ARP47419_P050 | Gong, Y. et al. Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins. Nat. Genet. 46, 588-94 (2014). 24793136 | 24793136 |
423 | FBXW7 | ARP47419_P050 | FBXW7 mediates high glucose‑induced SREBP‑1 expression in renal tubular cells of diabetic nephropathy under PI3K/Akt pathway regulation. Mol Med Rep. 23 (2021). 33537812 | 33537812 |
424 | FECH | ARP41682_T100 | Susceptibility to 5-aminolevulinic acid based photodynamic therapy in WHO I meningioma cells corresponds to ferrochelatase activity. Photochem Photobiol 235-41 87 1 November 2010 | 21073472 |
425 | FGF2 | ARP42005_P050 | MicroRNA-205 mediates endothelial progenitor functions in distraction osteogenesis by targeting the transcription regulator NOTCH2. Stem Cell Res Ther. 12, 101 (2021). 33536058 | 33536058 |
426 | FGF2 | OPPA00628 | The garlic-derived organosulfur compound diallyl trisulphide suppresses tissue factor function. Food Funct 2022 3 13 1246-1255 35022635 | 35022635 |
427 | FGF22 | OAAF02973 | Fibroblast growth factor 22 is a novel modulator of depression through interleukin-1β. CNS Neurosci Ther. 23, 907-916 (2017). 28948716 | 28948716 |
428 | FGFR1 | OAAB11171 | Oncogenic fusion protein BCR-FGFR1 requires the breakpoint cluster region-mediated oligomerization and chaperonin Hsp90 for activation. Haematologica. 105, 1262-1273 (2020). 31439673 | 31439673 |
429 | FGFR3 | OAAB11172 | Oncogenic driver FGFR3-TACC3 is dependent on membrane trafficking and ERK signaling. Oncotarget. 9, 34306-34319 (2018). 30344944 | 30344944 |
430 | FHL1 | ARP34378_T100 | Windpassinger, C. et al. An X-linked myopathy with postural muscle atrophy and generalized hypertrophy, termed XMPMA, is caused by mutations in FHL1. Am. J. Hum. Genet. 82, 88-99 (2008). 18179888 | 18179888 |
431 | FHL1 | ARP34378_T100 | Quinzii, C. M. et al. X-linked dominant scapuloperoneal myopathy is due to a mutation in the gene encoding four-and-a-half-LIM protein 1. Am. J. Hum. Genet. 82, 208-13 (2008). 18179901 | 18179901 |
432 | FHL1 | ARP34378_T100 | Schoser, B. et al. Consequences of mutations within the C terminus of the FHL1 gene. Neurology 73, 543-51 (2009). 19687455 | 19687455 |
433 | FHL1 | ARP34378_T100 | Gueneau, L. et al. Mutations of the FHL1 gene cause Emery-Dreifuss muscular dystrophy. Am. J. Hum. Genet. 85, 338-53 (2009). 19716112 | 19716112 |
434 | FHL1 | ARP34378_T100 | Sharma, P., Shathasivam, T., Ignatchenko, V., Kislinger, T. & Gramolini, A. O. Identification of an FHL1 protein complex containing ACTN1, ACTN4, and PDLIM1 using affinity purifications and MS-based protein-protein interaction analysis. Mol. Biosyst. 7, 1185-96 (2011). 21246116 | 21246116 |
435 | FHL1 | ARP34378_T100 | Dong, R. et al. Cells with dendritic cell morphology and immunophenotype, binuclear morphology, and immunosuppressive function in dendritic cell cultures. Cell. Immunol. 272, 1-10 (2011). 22053194 | 22053194 |
436 | FHL1 | ARP34378_T100 | Koike, K. et al. High prevalence of epigenetic inactivation of the human four and a half LIM domains 1 gene in human oral cancer. Int. J. Oncol. 42, 141-50 (2013). 23123766 | 23123766 |
437 | FHL1 | ARP34378_T100 | Loss of FHL1 induces an age-dependent skeletal muscle myopathy associated with myofibrillar and intermyofibrillar disorganization in mice. Hum Mol Genet. 23, 209-25 (2014). 23975679 | 23975679 |
438 | FHL1 | ARP34378_T100 | Fujii, T. et al. A case of adult-onset reducing body myopathy presenting a novel clinical feature, asymmetrical involvement of the sternocleidomastoid and trapezius muscles. J. Neurol. Sci. 343, 206-10 (2014). 24928078 | 24928078 |
439 | FHL1 | ARP34378_T100 | Fhl1 W122S causes loss of protein function and late-onset mild myopathy. Hum Mol Genet. 24, 714-26 (2015). 25274776 | 25274776 |
440 | FHL1 | ARP34378_T100 | Exome Sequencing Identified a Splice Site Mutation in FHL1 that Causes Uruguay Syndrome, an X-Linked Disorder With Skeletal Muscle Hypertrophy and Premature Cardiac Death. Circ Cardiovasc Genet. 9, 130-5 (2016). 26933038 | 26933038 |
441 | FHL1 | ARP34378_T100 | Immunohistochemistry on a panel of Emery-Dreifuss muscular dystrophy samples reveals nuclear envelope proteins as inconsistent markers for pathology. Neuromuscul. Disord. 27, 338-351 (2017). 28214269 | 28214269 |
442 | FHL1 | ARP34378_T100 | Cardiomyopathy and altered integrin-actin signaling in Fhl1 mutant female mice. Hum Mol Genet. 28, 209-219 (2019). 30260394 | 30260394 |
443 | FHL2 | ARP34506_T100 | Han, W. et al. FHL2 interacts with and acts as a functional repressor of Id2 in human neuroblastoma cells. Nucleic Acids Res. 37, 3996-4009 (2009). 19417068 | 19417068 |
444 | FHL2 | ARP34506_T100 | Saeki, Y. et al. Ligand-specific sequential regulation of transcription factors for differentiation of MCF-7 cells. BMC Genomics 10, 545 (2009). 19925682 | 19925682 |
445 | FMO3 | ARP44434_P050 | Vascular reactivity stimulated by TMA and TMAO: Are perivascular adipose tissue and endothelium involved? Pharmacol Res 2021 NULL 163 105273 33197599 | 33197599 |
446 | FOLH1 | OAAB10007 | Walder, K. K. et al. Immunohistological and electrophysiological evidence that N-acetylaspartylglutamate is a co-transmitter at the vertebrate neuromuscular junction. Eur. J. Neurosci. 37, 118-29 (2013). 23134476 | 23134476 |
447 | FOLR1 | ARP41427_P050 | Reinforcing one-carbon metabolism via folic acid/Folr1 promotes β-cell differentiation. Nat Commun. 12, 3362 (2021). 34099692 | 34099692 |
448 | FOSL1 | ARP31377_P050 | Yang, L. et al. Biological function and prognostic significance of peroxisome proliferator-activated receptor d in rectal cancer. Clin. Cancer Res. 17, 3760-70 (2011). 21499227 | 21499227 |
449 | FOSL1 | ARP31377_P050 | Seitz, O., Schürmann, C., Pfeilschifter, J., Frank, S. & Sader, R. Identification of the Fra-1 transcription factor in healing skin flaps transplants: a potential role as a negative regulator of VEGF release from keratinocytes. J. Craniomaxillofac. Surg. 40, 379-86 (2012). 21840727 | 21840727 |
450 | FOXA3 | ARP31945_P050 | Menga, A. et al. Insight into mechanism of in vitro insulin secretion increase induced by antipsychotic clozapine: role of FOXA1 and mitochondrial citrate carrier. Eur. Neuropsychopharmacol. 23, 978-87 (2013). 22959654 | 22959654 |
451 | FOXD1 | OAAB10686 | FOXD1 and Gal-3 Form a Positive Regulatory Loop to Regulate Lung Cancer Aggressiveness. Cancers (Basel). 11, (2019). 31795213 | 31795213 |
452 | FOXF1 | ARP32296_T100 | Lo, P.-K. et al. Cytoplasmic mislocalization of overexpressed FOXF1 is associated with the malignancy and metastasis of colorectal adenocarcinomas. Exp. Mol. Pathol. 94, 262-9 (2013). 23103611 | 23103611 |
453 | FOXF1 | ARP32296_T100 | Tamura, M. et al. Forkhead transcription factor FOXF1 is a novel target gene of the p53 family and regulates cancer cell migration and invasiveness. Oncogene (2013). doi:10.1038/onc.2013.427 24186199 | 24186199 |
454 | FOXF2 | ARP31694_T100 | The dual role of FOXF2 in regulation of DNA replication and the epithelial-mesenchymal transition in breast cancer progression. Cell. Signal. 28, 1502-19 (2016). 27377963 | 27377963 |
455 | FOXK2 | ARP34775_P050 | Komorek, J. et al. Adenovirus type 5 E1A and E6 proteins of low-risk cutaneous beta-human papillomaviruses suppress cell transformation through interaction with FOXK1/K2 transcription factors. J. Virol. 84, 2719-31 (2010). 20053746 | 20053746 |
456 | Foxl2 | ARP39574_P050 | The conserved sex regulator DMRT1 recruits SOX9 in sexual cell fate reprogramming. Nucleic Acids Res 2021 11 49 6144-6164 34096593 | 34096593 |
457 | FOXO3 | ARP38041_P050 | Foxo3a aggravates inflammation and induces apoptosis in IL-1-treated rabbit chondrocytes via positively regulating tenascin-c. Folia Histochem Cytobiol 2020 1 58 1-8 32003441 | 32003441 |
458 | FOXP1 | ARP32564_T100 | Jepsen, K., Gleiberman, A. S., Shi, C., Simon, D. I. & Rosenfeld, M. G. Cooperative regulation in development by SMRT and FOXP1. Genes Dev. 22, 740-5 (2008). 18347093 | 18347093 |
459 | FOXP1 | ARP32564_T100 | Konstantoulas, C. J., Parmar, M. & Li, M. FoxP1 promotes midbrain identity in embryonic stem cell-derived dopamine neurons by regulating Pitx3. J. Neurochem. 113, 836-47 (2010). 20175877 | 20175877 |
460 | FOXP1 | ARP32564_T100 | Tang, B. et al. Forkhead box protein p1 is a transcriptional repressor of immune signaling in the CNS: implications for transcriptional dysregulation in Huntington disease. Hum. Mol. Genet. 21, 3097-111 (2012). 22492998 | 22492998 |
461 | FOXP3 | ARP32743_T100 | Kawabata, A. et al. Naïve rat umbilical cord matrix stem cells significantly attenuate mammary tumor growth through modulation of endogenous immune responses. Cytotherapy 15, 586-97 (2013). 23474329 | 23474329 |
462 | FOXP3 | OAAB01500 | NOVA1 inhibition by miR-146b-5p in the remnant tissue microenvironment defines occult residual disease after gastric cancer removal. Oncotarget. 7, 2475-95 (2016). 26673617 | 26673617 |
463 | FPGS | ARP63438_P050 | A folylpoly-γ-glutamate synthase single nucleotide polymorphism associated with response to pemetrexed treatment combined with platinum for non-small cell lung cancer. Lung Cancer. 102, 15-20 (2016). 27987582 | 27987582 |
464 | FTCD | ARP41577_P050 | Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828 | 23103828 |
465 | FTH1 | ARP54620_P050 | Potrykus, J. et al. Fungal Iron Availability during Deep Seated Candidiasis Is Defined by a Complex Interplay Involving Systemic and Local Events. PLoS Pathog. 9, e1003676 (2013). 24146619 | 24146619 |
466 | FUBP1 | ARP35704_P050 | Milosevic, J., Bulau, P., Mortz, E. & Eickelberg, O. Subcellular fractionation of TGF-beta1-stimulated lung epithelial cells: a novel proteomic approach for identifying signaling intermediates. Proteomics 9, 1230-40 (2009). 19253281 | 19253281 |
467 | FUBP1 | ARP37732_T100 | Far Upstream Element-Binding Protein 1 Binds the 3' Untranslated Region of PKD2 and Suppresses Its Translation. J. Am. Soc. Nephrol. 27, 2645-57 (2016). 26839368 | 26839368 |
468 | FUNDC1 | ARP53281_P050 | FUNDC1-dependent mitochondria-associated endoplasmic reticulum membranes are involved in angiogenesis and neoangiogenesis. Nat Commun 2021 1 12 2616 33972548 | 33972548 |
469 | FZD4 | ARP41266_P050 | McIver, S. C. et al. A unique combination of male germ cell miRNAs coordinates gonocyte differentiation. PLoS One 7, e35553 (2012). 22536405 | 22536405 |
470 | FZD4 | ARP41266_P050 | Gonzalez, P., Fernandez-Martos, C. M., Gonzalez-Fernandez, C., Arenas, E. & Rodriguez, F. J. Spatio-temporal expression pattern of frizzled receptors after contusive spinal cord injury in adult rats. PLoS One 7, e50793 (2012). 23251385 | 23251385 |
471 | FZD4 | ARP41266_P050 | Wang, L. et al. Impact of laminitis on the canonical Wnt signaling pathway in basal epithelial cells of the equine digital laminae. PLoS One 8, e56025 (2013). 23405249 | 23405249 |
472 | FZD7 | ARP41251_P050 | Ueno, K. et al. Frizzled-7 as a potential therapeutic target in colorectal cancer. Neoplasia 10, 697-705 (2008). 18592008 | 18592008 |
473 | FZD7 | ARP41251_P050 | Gökmen-Polar, Y. et al. Dual targeting of EphA2 and ER restores tamoxifen sensitivity in ER/EphA2-positive breast cancer. Breast Cancer Res. Treat. 127, 375-84 (2011). 20602165 | 20602165 |
474 | FZD7 | ARP41251_P050 | Ohba, S., Lanigan, T. M. & Roessler, B. J. Leptin receptor JAK2/STAT3 signaling modulates expression of Frizzled receptors in articular chondrocytes. Osteoarthritis Cartilage 18, 1620-9 (2010). 20868760 | 20868760 |
475 | FZD7 | ARP41251_P050 | Schmuck, R. et al. Genotypic and phenotypic characterization of side population of gastric cancer cell lines. Am. J. Pathol. 178, 1792-804 (2011). 21435459 | 21435459 |
476 | FZD7 | ARP41251_P050 | McIver, S. C. et al. A unique combination of male germ cell miRNAs coordinates gonocyte differentiation. PLoS One 7, e35553 (2012). 22536405 | 22536405 |
477 | FZD8 | OAEB02431 | Yin, S. et al. Tumor-initiating cells and FZD8 play a major role in drug resistance in triple-negative breast cancer. Mol. Cancer Ther. 12, 491-8 (2013). 23445611 | 23445611 |
478 | FZD9 | ARP41253_T100 | Tennis, M. A. et al. Prostacyclin inhibits non-small cell lung cancer growth by a frizzled 9-dependent pathway that is blocked by secreted frizzled-related protein 1. Neoplasia 12, 244-53 (2010). 20234818 | 20234818 |
479 | G3BP1 | ARP37713_T100 | Disrupting the HDAC6-ubiquitin interaction impairs infection by influenza and Zika virus and cellular stress pathways. Cell Rep 2022 4 39 110736 35476995 | 35476995 |
480 | G6PC | ARP44224_P050 | Iwasa, M. et al. Branched-chain amino acid supplementation reduces oxidative stress and prolongs survival in rats with advanced liver cirrhosis. PLoS One 8, e70309 (2013). 23936183 | 23936183 |
481 | G6pc | ARP44223_P050 | The E3 ubiquitin-protein ligase Trim31 alleviates non-alcoholic fatty liver disease by targeting Rhbdf2 in mouse hepatocytes. Nat Commun 2022 1 13 1052 35217669 | 35217669 |
482 | GABRA5 | ARP34984_P050 | Extrasynaptic α5GABAA receptors on proprioceptive afferents produce a tonic depolarization that modulates sodium channel function in the rat spinal cord. J Neurophysiol. 120, 2953-2974 (2018). 30256739 | 30256739 |
483 | GABRP | AVARP13034_P050 | Use of a human embryonic stem cell model to discover GABRP, WFDC2, VTCN1 and ACTC1 as markers of early first trimester human trophoblast. Mol Hum Reprod. 26, 425-440 (2020) 32359161 | 32359161 |
484 | GABRR2 | ARP35060_P050 | Fatemi, S. H., Folsom, T. D., Rooney, R. J. & Thuras, P. D. mRNA and protein expression for novel GABAA receptors θ and ρ2 are altered in schizophrenia and mood disorders; relevance to FMRP-mGluR5 signaling pathway. Transl. Psychiatry 3, e271 (2013). 23778581 | 23778581 |
485 | GADD45B | ARP48346_P050 | Babu, E. et al. Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate. Oncogene 30, 4026-37 (2011). 21505039 | 21505039 |
486 | GADD45B | ARP48346_P050 | Dong, R. et al. Cells with dendritic cell morphology and immunophenotype, binuclear morphology, and immunosuppressive function in dendritic cell cultures. Cell. Immunol. 272, 1-10 (2011). 22048458 | 22048458 |
487 | GADD45B | ARP48346_P050 | Role of Growth Arrest and DNA Damage-Inducible, Beta in Alcohol-Drinking Behaviors. Alcohol. Clin. Exp. Res. 40, 263-72 (2016). 26842245 | 26842245 |
488 | GADD45B | ARP48346_P050 | BDNF rs6265 methylation and genotype interact on risk for schizophrenia. Epigenetics. 11, 11-23 (2016). 26889735 | 26889735 |
489 | GADD45B | ARP48346_P050 | ALK5 signaling pathway mediates neurogenesis and functional recovery after cerebral ischemia/reperfusion in rats via Gadd45b. Cell Death Dis. 10, 360 (2019). 31043581 | 31043581 |
490 | GAGE12B | OAAB07499 | Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma. Nat Commun. 12, 7142 (2021). 34880251 | 34880251 |
491 | GALR2 | OABF00517 | Spexin Acts as Novel Regulator for Bile Acid Synthesis. Front Physiol. 9, 378 (2018). 29692737 | 29692737 |
492 | GAPDH | ARP40175_P050 | Fu, Y. et al. ABCA12 Regulates ABCA1-Dependent Cholesterol Efflux from Macrophages and the Development of Atherosclerosis. Cell Metab. 18, 225-38 (2013). 23931754 | 23931754 |
493 | GAPDH | ARP40175_P050 | Kalinec, G. M. et al. Acetaminophen and NAPQI are toxic to auditory cells via oxidative and endoplasmic reticulum stress-dependent pathways. Hear. Res. 313, 26-37 (2014). 24793116 | 24793116 |
494 | GAPDH | OAAD00231 | Kam, A. et al. Gallic acid protects against endothelial injury by restoring the depletion of DNA methyltransferase 1 and inhibiting proteasome activities. Int. J. Cardiol. 171, 231-42 (2014). 24388544 | 24388544 |
495 | GAPDH | OAAD00231 | Expression of Kruppel-like factor 8 and Ki67 in lung adenocarcinoma and prognosis. Exp Ther Med. 14, 1351-1356 (2017). 28810596 | 28810596 |
496 | GAPDH | OASA03787 | The analysis of heterotaxy patients reveals new loss-of-function variants of GRK5. Sci Rep. 6, 33231 (2016). 27618959 | 27618959 |
497 | GATA2 | ARP31855_T100 | Mammoto, A. et al. A mechanosensitive transcriptional mechanism that controls angiogenesis. Nature 457, 1103-8 (2009). 19242469 | 19242469 |
498 | GATA2 | ARP31855_T100 | Huang, Y.-J. et al. The functional IGFBP7 promoter -418G>A polymorphism and risk of head and neck cancer. Mutat. Res. 702, 32-9 (2010). 20599521 | 20599521 |
499 | GATA2 | ARP31855_T100 | Jack, B. H. A. & Crossley, M. GATA proteins work together with friend of GATA (FOG) and C-terminal binding protein (CTBP) co-regulators to control adipogenesis. J. Biol. Chem. 285, 32405-14 (2010). 20705609 | 20705609 |
500 | GATA2 | ARP31855_T100 | Fujiwara, T. et al. Gene expression profiling identifies HOXB4 as a direct downstream target of GATA-2 in human CD34+ hematopoietic cells. PLoS One 7, e40959 (2012). 23028422 | 23028422 |
501 | GATA2 | ARP31855_T100 | Wang, F. et al. A regulatory circuit comprising GATA1/2 switch and microRNA-27a/24 promotes erythropoiesis. Nucleic Acids Res. 42, 442-57 (2014). 24049083 | 24049083 |
502 | GATA6 | ARP31859_P050 | Kallas, A., Pook, M., Trei, A. & Maimets, T. SOX2 Is Regulated Differently from NANOG and OCT4 in Human Embryonic Stem Cells during Early Differentiation Initiated with Sodium Butyrate. Stem Cells Int. 2014, 298163 (2014). 24707296 | 24707296 |
503 | GCDH | ARP43559_T100 | Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 | 24465277 |
504 | GCLC | ARP54576_P050 | Tomasi, M. L. et al. Molecular mechanisms of lipopolysaccharide-mediated inhibition of glutathione synthesis in mice. Free Radic. Biol. Med. 68, 148-58 (2014). 24296246 | 24296246 |
505 | GCLC | ARP54577_P050 | Bardag-Gorce, F. et al. Proteasome inhibitor up regulates liver antioxidative enzymes in rat model of alcoholic liver disease. Exp. Mol. Pathol. 90, 123-30 (2011). 21036165 | 21036165 |
506 | GCLC | ARP54577_P050 | Ramani, K., Tomasi, M. L., Yang, H., Ko, K. & Lu, S. C. Mechanism and significance of changes in glutamate-cysteine ligase expression during hepatic fibrogenesis. J. Biol. Chem. 287, 36341-55 (2012). 22942279 | 22942279 |
507 | GCLC | ARP54577_P050 | Saturated Fatty Acid Activates T Cell Inflammation Through a Nicotinamide Nucleotide Transhydrogenase (NNT)-Dependent Mechanism. Biomolecules. 9, (2019). 30823587 | 30823587 |
508 | GCLC | ARP54577_P050 | Cysteine improves boar sperm quality via glutathione biosynthesis during the liquid storage. Anim Biosci 2022 2 35 166-176 34445846 | 34445846 |
509 | GCLM | ARP54624_P050 | Ramani, K., Tomasi, M. L., Yang, H., Ko, K. & Lu, S. C. Mechanism and significance of changes in glutamate-cysteine ligase expression during hepatic fibrogenesis. J. Biol. Chem. 287, 36341-55 (2012). 22942279 | 22942279 |
510 | GCLM | ARP54624_P050 | Tomasi, M. L. et al. Molecular mechanisms of lipopolysaccharide-mediated inhibition of glutathione synthesis in mice. Free Radic. Biol. Med. 68, 148-58 (2014). 24296246 | 24296246 |
511 | GCM1 | P100836_P050 | Baczyk, D. et al. Glial cell missing-1 transcription factor is required for the differentiation of the human trophoblast. Cell Death Differ. 16, 719-27 (2009). 19219068 | 19219068 |
512 | GCM1 | P100836_P050 | Sivasubramaniyam, T. et al. Where polarity meets fusion: role of Par6 in trophoblast differentiation during placental development and preeclampsia. Endocrinology 154, 1296-309 (2013). 23341197 | 23341197 |
513 | GCM1 | P100836_P050 | Kumar, P., Luo, Y., Tudela, C., Alexander, J. M. & Mendelson, C. R. The c-Myc-regulated microRNA-17~92 (miR-17~92) and miR-106a~363 clusters target hCYP19A1 and hGCM1 to inhibit human trophoblast differentiation. Mol. Cell. Biol. 33, 1782-96 (2013). 23438603 | 23438603 |
514 | GCM1 | P100836_P050 | Gene Expression Profiling Reveals a Novel Regulatory Role for Sox21 Protein in Mouse Trophoblast Stem Cell Differentiation. J. Biol. Chem. 290, 30152-62 (2015). 26491013 | 26491013 |
515 | GCM1 | P100836_P050 | Augmented trophoblast cell death in preeclampsia can proceed via ceramide-mediated necroptosis. Cell Death Dis. 8, e2590 (2017). 28151467 | 28151467 |
516 | GDF1 | OACD03794 | Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma. Nat Commun. 12, 7142 (2021). 34880251 | 34880251 |
517 | GJB1 | ARP36600_T100 | Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 | 24465277 |
518 | GLI2 | ARP31885_P050 | Histological, cellular and behavioural analyses of effects of chemotherapeutic agent cyclophosphamide in the developing cerebellum. Cell Prolif. 52, e12608 (2019). 30932251 | 30932251 |
519 | GLI2 | ARP31885_T100 | Kim, Y. et al. Selective down-regulation of glioma-associated oncogene 2 inhibits the proliferation of hepatocellular carcinoma cells. Cancer Res. 67, 3583-93 (2007). 17440069 | 17440069 |
520 | GLI2 | ARP31885_T100 | Kiprilov, E. N. et al. Human embryonic stem cells in culture possess primary cilia with hedgehog signaling machinery. J. Cell Biol. 180, 897-904 (2008). 18332216 | 18332216 |
521 | GLI2 | ARP31885_T100 | Kabasawa, Y. et al. Amelogenin positive cells scattered in the interstitial component of odontogenic fibromas. J. Clin. Pathol. 61, 851-5 (2008). 18344235 | 18344235 |
522 | GLI2 | ARP31885_T100 | Omenetti, A. et al. The hedgehog pathway regulates remodelling responses to biliary obstruction in rats. Gut 57, 1275-82 (2008). 18375471 | 18375471 |
523 | GLI2 | ARP31885_T100 | Omenetti, A. et al. Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans. J. Clin. Invest. 118, 3331-42 (2008). 18802480 | 18802480 |
524 | GLI2 | ARP31885_T100 | Takanaga, H. et al. Gli2 is a novel regulator of sox2 expression in telencephalic neuroepithelial cells. Stem Cells 27, 165-74 (2009). 18927476 | 18927476 |
525 | GLI2 | ARP31885_T100 | Madison, B. B., McKenna, L. B., Dolson, D., Epstein, D. J. & Kaestner, K. H. FoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestine. J. Biol. Chem. 284, 5936-44 (2009). 19049965 | 19049965 |
526 | GLI2 | ARP31885_T100 | Wall, D. S. et al. Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity. J. Cell Biol. 184, 101-12 (2009). 19124651 | 19124651 |
527 | GLI2 | ARP31885_T100 | Syn, W.-K. et al. Role for hedgehog pathway in regulating growth and function of invariant NKT cells. Eur. J. Immunol. 39, 1879-92 (2009). 19544307 | 19544307 |
528 | GLI2 | ARP31885_T100 | Kim, J. E. et al. Sonic hedgehog signaling proteins and ATP-binding cassette G2 are aberrantly expressed in diffuse large B-cell lymphoma. Mod. Pathol. 22, 1312-20 (2009). 19593328 | 19593328 |
529 | GLI2 | ARP31885_T100 | Ho, L. et al. Gli2 and p53 cooperate to regulate IGFBP-3- mediated chondrocyte apoptosis in the progression from benign to malignant cartilage tumors. Cancer Cell 16, 126-36 (2009). 19647223 | 19647223 |
530 | GLI2 | ARP31885_T100 | Kim, W.-Y. et al. GSK-3 is a master regulator of neural progenitor homeostasis. Nat. Neurosci. 12, 1390-7 (2009). 19801986 | 19801986 |
531 | GLI2 | ARP31885_T100 | Nakamura, K. et al. Hedgehog promotes neovascularization in pancreatic cancers by regulating Ang-1 and IGF-1 expression in bone-marrow derived pro-angiogenic cells. PLoS One 5, e8824 (2010). 20098680 | 20098680 |
532 | GLI2 | ARP31885_T100 | Youssef, K. K. et al. Identification of the cell lineage at the origin of basal cell carcinoma. Nat. Cell Biol. 12, 299-305 (2010). 20154679 | 20154679 |
533 | GLI2 | ARP31885_T100 | Peacock, Z. S., Cox, D. & Schmidt, B. L. Involvement of PTCH1 mutations in the calcifying epithelial odontogenic tumor. Oral Oncol. 46, 387-92 (2010). 20371205 | 20371205 |
534 | GLI2 | ARP31885_T100 | Coon, V. et al. Molecular therapy targeting Sonic hedgehog and hepatocyte growth factor signaling in a mouse model of medulloblastoma. Mol. Cancer Ther. 9, 2627-36 (2010). 20807782 | 20807782 |
535 | GLI2 | ARP31885_T100 | Schneider, S. et al. Expression of the Sonic hedgehog pathway in squamous cell carcinoma of the skin and the mucosa of the head and neck. Head Neck 33, 244-50 (2011). 20848446 | 20848446 |
536 | GLI2 | ARP31885_T100 | Malek, R., Matta, J., Taylor, N., Perry, M. E. & Mendrysa, S. M. The p53 inhibitor MDM2 facilitates Sonic Hedgehog-mediated tumorigenesis and influences cerebellar foliation. PLoS One 6, e17884 (2011). 21437245 | 21437245 |
537 | GLI2 | ARP31885_T100 | Jung, I. H., Jung, D. E., Park, Y. N., Song, S. Y. & Park, S. W. Aberrant Hedgehog ligands induce progressive pancreatic fibrosis by paracrine activation of myofibroblasts and ductular cells in transgenic zebrafish. PLoS One 6, e27941 (2011). 22164219 | 22164219 |
538 | GLI2 | ARP31885_T100 | Yang, L. et al. Hedgehog signaling activation in the development of squamous cell carcinoma and adenocarcinoma of esophagus. Int. J. Biochem. Mol. Biol. 3, 46-57 (2012). 22509480 | 22509480 |
539 | GLI2 | ARP31885_T100 | Tostar, U., Finta, C., Rahman, M. F.-U., Shimokawa, T. & Zaphiropoulos, P. G. Novel mechanism of action on Hedgehog signaling by a suppressor of fused carboxy terminal variant. PLoS One 7, e37761 (2012). 22666390 | 22666390 |
540 | GLI2 | ARP31885_T100 | Bosco-Clément, G. et al. Targeting Gli transcription activation by small molecule suppresses tumor growth. Oncogene 33, 2087-97 (2014). 23686308 | 23686308 |
541 | GLI2 | ARP31885_T100 | Li, Y. et al. Gene expression profiling reveals the heterogeneous transcriptional activity of Oct3/4 and its possible interaction with Gli2 in mouse embryonic stem cells. Genomics 102, 456-67 24121003 | 24121003 |
542 | GLI2 | ARP31885_T100 | Non-canonical Hedgehog signaling activation in ovarian borderline tumors and ovarian carcinomas. Int J Oncol. 51, 1869-1877 (2017). 29039491 | 29039491 |
543 | GLI2 | ARP31885_T100 | Regulation of Survivin Isoform Expression by GLI Proteins in Ovarian Cancer. Cells. 8, (2019). 30736319 | 30736319 |
544 | GLI-2 | ARP31885_P050 | Impact of Sonic Hedgehog Pathway Expression on Outcome in HPV Negative Head and Neck Carcinoma Patients after Surgery and Adjuvant Radiotherapy. PLoS ONE. 11, e0167665 (2016). 27918595 | 27918595 |
545 | GLIS2 | ARP30037_P050 | Attanasio, M. et al. Loss of GLIS2 causes nephronophthisis in humans and mice by increased apoptosis and fibrosis. Nat. Genet. 39, 1018-24 (2007). 17618285 | 17618285 |
546 | GLIS2 | ARP30037_P050 | Prominin-1 controls stem cell activation by orchestrating ciliary dynamics. EMBO J. 38, (2019). 30523147 | 30523147 |
547 | GLIS2 | ARP30037_P050 | An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis. Sci Adv. 7, eabf6063 (2021). 34705506 | 34705506 |
548 | GLRA1 | OAPC00117 | Non-uniform changes in membrane receptors in the rat urinary bladder following outlet obstruction. Eur. J. Pharmacol. 762, 82-8 (2015). 26004535 | 26004535 |
549 | GLS2 | ARP43562_T100 | Toriumi, K. et al. Prenatal NMDA receptor antagonism impaired proliferation of neuronal progenitor, leading to fewer glutamatergic neurons in the prefrontal cortex. Neuropsychopharmacology 37, 1387-96 (2012). 22257896 | 22257896 |
550 | GLS2 | ARP43562_T100 | Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 | 24465277 |
551 | GLUD1 | ARP45709_P050 | Expression of human GLUD1 and GLUD2 glutamate dehydrogenases in steroid producing tissues. Mol. Cell. Endocrinol. 415, 1-11 (2015). 26241911 | 26241911 |
552 | GLUD1 | ARP45709_P050 | Widening Spectrum of Cellular and Subcellular Expression of Human GLUD1 and GLUD2 Glutamate Dehydrogenases Suggests Novel Functions. Neurochem. Res. 42, 92-107 (2017). 27422263 | 27422263 |
553 | GNAS | ARP42693_P050 | Masyuk, A. I. et al. Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling. Am. J. Physiol. Gastrointest. Liver Physiol. 304, G1013-24 (2013). 23578785 | 23578785 |
554 | GNAS | ARP42693_P050 | Moreno-Smith, M. et al. Biologic effects of dopamine on tumor vasculature in ovarian carcinoma. Neoplasia 15, 502-10 (2013). 23633922 | 23633922 |
555 | GNAT3 | OAEB00418 | Immunohistochemical Analysis of Human Vallate Taste Buds. Chem Senses. 40, 655-60 (2015). 26400924 | 26400924 |
556 | GNAT3 | OAEB00418 | The Role of 5-HT3 Receptors in Signaling from Taste Buds to Nerves. J Neurosci. 35, 15984-95 (2015). 26631478 | 26631478 |
557 | GNAT3 | OAEB00418 | 5-HT3A -driven green fluorescent protein delineates gustatory fibers innervating sour-responsive taste cells: A labeled line for sour taste?. J Comp Neurol. 525, 2358-2375 (2017). 28316078 | 28316078 |
558 | GNAT3 | OAEB00418 | Michael A Kohanski, et al. Solitary chemosensory cells are a primary epithelial source of IL-25 in patients with chronic rhinosinusitis with nasal polyps. 460-469.e7 (2018). 29778504 | 29778504 |
559 | GNAT3 | OAEB00418 | Chemical receptors of the arytenoid: A comparison of human and mouse. Laryngoscope. 130, 423-430 (2020). 30908677 | 30908677 |
560 | GNAT3 | OAEB00418 | Expression of Bitter Taste Receptors and Solitary Chemosensory Cell Markers in the Human Sinonasal Cavity. Chem Senses. 44, 483-495 (2019). 31231752 | 31231752 |
561 | GNAT3 | OAEB00418 | A Subset of Olfactory Sensory Neurons Express Forkhead Box J1-Driven eGFP. Chem Senses. 44, 663-671 (2019). 31504289 | 31504289 |
562 | GNAT3 | OAEB00418 | Zika virus infection in chemosensory cells. J Neurovirol. 26, 371-381 (2020) 32144727 | 32144727 |
563 | GNAT3 | OAEB00418 | Functional expression of TMEM16A in taste bud cells. J Physiol. 599, 3697-3714 (2021) 34089532 | 34089532 |
564 | GNAT3 | OAEB00418 | Whole-Brain Mapping of the Expression Pattern of T1R2, a Subunit Specific to the Sweet Taste Receptor. Front Neuroanat. 15, 751839 (2021). 34776881 | 34776881 |
565 | GNAT3 | OAEB00418 | Whole-Brain Mapping of the Expression Pattern of T1R2, a Subunit Specific to the Sweet Taste Receptor. Front Neuroanat. 15, 751839 (2021). 34578940 | 34578940 |
566 | GNAT3 | OAEB00418 | METTL3-mediated m6A RNA methylation regulates dorsal lingual epithelium homeostasis. Int J Oral Sci 2022 1 14 26 35581183 | 35581183 |
567 | GNB3 | OALA06860 | No evidence for age-related alterations in the marmoset retina. Front Neuroanat 945295 16 NULL September 2022 | 36120100 |
568 | GOT1 | ARP48205_P050 | Takeda, K., Ishida, A., Takahashi, K. & Ueda, T. Synaptic vesicles are capable of synthesizing the VGLUT substrate glutamate from a-ketoglutarate for vesicular loading. J. Neurochem. 121, 184-96 (2012). 22309504 | 22309504 |
569 | GOT1 | ARP48205_P050 | Povlsen, J. A. et al. Protection against myocardial ischemia-reperfusion injury at onset of type 2 diabetes in Zucker diabetic fatty rats is associated with altered glucose oxidation. PLoS One 8, e64093 (2013). 23704975 | 23704975 |
570 | GOT2 | ARP43518_T100 | Vitamin C and E Treatment Blocks Changes in Kynurenine Metabolism Triggered by Three Weeks of Sprint Interval Training in Recreationally Active Elderly Humans. Antioxidants (Basel). 10 (2021). 34573075 | 34573075 |
571 | GOT2 | ARP43518_T100 | The day/night proteome in the murine heart. Am J Physiol Regul Integr Comp Physiol 2014 2 307 R121-37 24789993 | 24789993 |
572 | GPC1 | OAMA02173 | Decreased expression of GPC1 in human skin keratinocytes and epidermis during ageing. Exp Gerontol 2019 NULL 126 110693 31430521 | 31430521 |
573 | GPC3 | ARP37665_T100 | Bhave, V. S. et al. Regulation of liver growth by glypican 3, CD81, hedgehog, and Hhex. Am. J. Pathol. 183, 153-9 (2013). 23665349 | 23665349 |
574 | GPC3 | ARP37665_T100 | Plasmodium parasite as an effective hepatocellular carcinoma antigen glypican-3 delivery vector. Oncotarget. 8, 24785-24796 (2017). 28445973 | 28445973 |
575 | GPX3 | ARP41491_P050 | Maccarrone, G. et al. Psychiatric patient stratification using biosignatures based on cerebrospinal fluid protein expression clusters. J. Psychiatr. Res. 47, 1572-80 (2013). 23962679 | 23962679 |
576 | GPX3 | ARP41491_P050 | Methionine supply alters mammary gland antioxidant gene networks via phosphorylation of nuclear factor erythroid 2-like 2 (NFE2L2) protein in dairy cows during the periparturient period. J Dairy Sci. 101, 8505-8512 (2018). 29908802 | 29908802 |
577 | GRHL3 | ARP33196_P050 | Yu, Z., Mannik, J., Soto, A., Lin, K. K. & Andersen, B. The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation. EMBO J. 28, 1890-903 (2009). 19494835 | 19494835 |
578 | GRHL3 | ARP39489_P050 | Sakurai, T. et al. Involvement of leucine zipper transcription factor-like protein 1 (Lztfl1) in the attenuation of cognitive impairment by exercise training. Biochem. Biophys. Res. Commun. 416, 125-9 (2011). 22094257 | 22094257 |
579 | GRHL3 | ARP39489_T100 | Lack of IRF6 Disrupts Human Epithelial Homeostasis by Altering Colony Morphology, Migration Pattern, and Differentiation Potential of Keratinocytes. Front Cell Dev Biol. 9, 718066 (2021) 34660580 | 34660580 |
580 | GRIK2 | ARP35515_T100 | Funk, J. A. et al. Characterization of renal toxicity in mice administered the marine biotoxin domoic Acid. J. Am. Soc. Nephrol. 25, 1187-97 (2014). 24511141 | 24511141 |
581 | GRK5 | ARP54750_P050 | The analysis of heterotaxy patients reveals new loss-of-function variants of GRK5. Sci Rep. 6, 33231 (2016). 27618959 | 27618959 |
582 | GSC | ARP32174_P050 | Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity. Neurotoxicol Teratol. 52, 181-93 (2015). 26386178 | 26386178 |
583 | GSS | OAAB04008 | Ramani, K., Tomasi, M. L., Yang, H., Ko, K. & Lu, S. C. Mechanism and significance of changes in glutamate-cysteine ligase expression during hepatic fibrogenesis. J. Biol. Chem. 287, 36341-55 (2012). 22942279 | 22942279 |
584 | GTPBP9 | ARP40744_P050 | Zhang, J., Rubio, V., Lieberman, M. W. & Shi, Z.-Z. OLA1, an Obg-like ATPase, suppresses antioxidant response via nontranscriptional mechanisms. Proc. Natl. Acad. Sci. U. S. A. 106, 15356-61 (2009). 19706404 | 19706404 |
585 | GUCY2X | OACA09780 | Role of uroguanylin's signalling pathway in the development of ischaemic stroke. Eur J Neurosci 3720-3737 56 1 July 2022 | 35445449 |
586 | GUSB | ARP44234_T100 | Beta-Glucuronidase Catalyzes Deconjugation and Activation of Curcumin-Glucuronide in Bone. J Nat Prod. 82, 500-509 (2019). 30794412 | 30794412 |
587 | GUSB | ARP44234_T100 | Chemopreventive efficacy of oral curcumin: a prodrug hypothesis. FASEB J. 33, 9453-9465 (2019) 31136203 | 31136203 |
588 | GUSB | ARP44234_T100 | Bone-Specific Metabolism of Dietary Polyphenols in Resorptive Bone Diseases. Mol Nutr Food Res. 64, e2000072 (2020) 32506808 | 32506808 |
589 | GZMB | OAAF01817 | Influenza A surface glycosylation and vaccine design. Proc. Natl. Acad. Sci. U.S.A. 114, 280-285 (2017). 28028222 | 28028222 |
590 | GZMH | ARP42686_T100 | Deep immune profiling by mass cytometry links human T and NK cell differentiation and cytotoxic molecule expression patterns. J Immunol Methods. 453, 44472 (2018). 28322863 | 28322863 |
591 | HADHB | ARP48133_P050 | Gerin, I. et al. Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation. J. Biol. Chem. 285, 33652-61 (2010). 20732877 | 20732877 |
592 | HADHB | ARP48133_P050 | The nuclear receptor FXR uncouples the actions of miR-33 from SREBP-2. Arterioscler Thromb Vasc Biol. 35, 787-95 (2015). 25593129 | 25593129 |
593 | HADHB | ARP48133_P050 | TXNIP regulates myocardial fatty acid oxidation via miR-33a signaling. Am. J. Physiol. Heart Circ. Physiol. 311, H64-75 (2016). 27199118 | 27199118 |
594 | HADHB | ARP48133_P050 | Defining decreased protein succinylation of failing human cardiac myofibrils in ischemic cardiomyopathy. J Mol Cell Cardiol. 138, 304-317 (2020). 31836543 | 31836543 |
595 | HAL | ARP45694_T100 | Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 | 24465277 |
596 | HBC | OAAI00128 | Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly. Nat Commun. 10, 2184 (2019). 31097716 | 31097716 |
597 | HDAC2 | ARP32618_P050 | Mta2 promotes Tipin-dependent maintenance of replication fork integrity. Cell Cycle. 13, 2120-8 (2014). 24830473 | 24830473 |
598 | HDAC3 | OAAB09604 | Proteomic analysis identifies NPTX1 and HIP1R as potential targets of histone deacetylase-3-mediated neurodegeneration. Exp Biol Med (Maywood). 243, 627-638 (2018). 29486577 | 29486577 |
599 | HDAC9 | ARP42788_T100 | Milde, T. et al. HDAC5 and HDAC9 in medulloblastoma: novel markers for risk stratification and role in tumor cell growth. Clin. Cancer Res. 16, 3240-52 (2010). 20413433 | 20413433 |
600 | HDAC9 | ARP42788_T100 | Hang, C. T. et al. Chromatin regulation by Brg1 underlies heart muscle development and disease. Nature 466, 62-7 (2010). 20596014 | 20596014 |
601 | HDAC9 | ARP42788_T100 | Spallotta, F. et al. Detrimental effect of class-selective histone deacetylase inhibitors during tissue regeneration following hindlimb ischemia. J. Biol. Chem. 288, 22915-29 (2013). 23836913 | 23836913 |
602 | HES1 | ARP32372_T100 | Tilley, A. E. et al. Down-regulation of the notch pathway in human airway epithelium in association with smoking and chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 179, 457-66 (2009). 19106307 | 19106307 |
603 | HES1 | ARP32372_T100 | Schreck, K. C. et al. The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance. Clin. Cancer Res. 16, 6060-70 (2010). 21169257 | 21169257 |
604 | HES1 | ARP32372_T100 | Ma, W. et al. hCLP46 regulates U937 cell proliferation via Notch signaling pathway. Biochem. Biophys. Res. Commun. 408, 84-8 (2011). 21458412 | 21458412 |
605 | HES1 | ARP32372_T100 | Bennani-Baiti, I. M. et al. Notch signalling is off and is uncoupled from HES1 expression in Ewing’s sarcoma. J. Pathol. 225, 353-63 (2011). 21984123 | 21984123 |
606 | HES1 | ARP32372_T100 | Asnaghi, L. et al. Notch signaling promotes growth and invasion in uveal melanoma. Clin. Cancer Res. 18, 654-65 (2012). 22228632 | 22228632 |
607 | HES1 | ARP32372_T100 | Guiu, J. et al. Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling. J. Exp. Med. 210, 71-84 (2013). 23267012 | 23267012 |
608 | HES1 | ARP32372_T100 | Chu, Q., Liu, L. & Wang, W. Overexpression of hCLP46 enhances Notch activation and regulates cell proliferation in a cell type-dependent manner. Cell Prolif. 46, 254-62 (2013). 23692084 | 23692084 |
609 | Hes1 | ARP32372_T100 | Ma, L. et al. Atractylenolide I-mediated Notch pathway inhibition attenuates gastric cancer stem cell traits. Biochem. Biophys. Res. Commun. 450, 353-9 (2014). 24944018 | 24944018 |
610 | HES1 | ARP32372_T100 | Asnaghi, L. et al. Hypoxia Promotes Uveal Melanoma Invasion through Enhanced Notch and MAPK Activation. PLoS One 9, e105372 (2014). 25166211 | 25166211 |
611 | HES1 | ARP32372_T100 | Therapeutic targeting of HES1 transcriptional programs in T-ALL. Blood. 125, 2806-14 (2015). 25784680 | 25784680 |
612 | HES1 | ARP32372_T100 | Rac1 contributes to cerebral ischemia reperfusion-induced injury in mice by regulation of Notch2. Neuroscience. 306, 100-14 (2015). 26299339 | 26299339 |
613 | HES1 | ARP32372_T100 | Targeting Notch Signaling and Autophagy Increases Cytotoxicity in Glioblastoma Neurospheres. Brain Pathol. 26, 713-723 (2016). 26613556 | 26613556 |
614 | HES1 | ARP32372_T100 | CDKN2B deletion is essential for pancreatic cancer development instead of unmeaningful co-deletion due to juxtaposition to CDKN2A. Oncogene. 37, 128-138 (2018). 28892048 | 28892048 |
615 | HES1 | ARP32372_T100 | A novel pancreatic cancer model originated from transformation of acinar cells in adult tree shrew, a primate-like animal. Dis Model Mech. 12, (2019). 30910991 | 30910991 |
616 | HEY1 | ARP32512_P050 | Rac1 contributes to cerebral ischemia reperfusion-induced injury in mice by regulation of Notch2. Neuroscience. 306, 100-14 (2015). 26299339 | 26299339 |
617 | HEY1 | ARP32512_P050 | Nuclear Factor I Represses the Notch Effector HEY1 in Glioblastoma. Neoplasia. 20, 1023-1037 (2018). 30195713 | 30195713 |
618 | HGF | ARP44317_P050 | Sen, B., Peng, S., Saigal, B., Williams, M. D. & Johnson, F. M. Distinct interactions between c-Src and c-Met in mediating resistance to c-Src inhibition in head and neck cancer. Clin. Cancer Res. 17, 514-24 (2011). 21106725 | 21106725 |
619 | HGF | ARP44317_P050 | Williams, C. M. et al. Autocrine-controlled formation and function of tissue-like aggregates by primary hepatocytes in micropatterned hydrogel arrays. Tissue Eng. Part A 17, 1055-68 (2011). 21121876 | 21121876 |
620 | HGF | ARP44317_P050 | Zampell, J. C. et al. Lymphatic function is regulated by a coordinated expression of lymphangiogenic and anti-lymphangiogenic cytokines. Am. J. Physiol. Cell Physiol. 302, C392-404 (2012). 21940662 | 21940662 |
621 | HGF | ARP44317_P050 | Ji, R. et al. The differentiation of MSCs into functional hepatocyte-like cells in a liver biomatrix scaffold and their transplantation into liver-fibrotic mice. Biomaterials 33, 8995-9008 (2012). 22985996 | 22985996 |
622 | HGF | ARP44317_P050 | Nejak-Bowen, K., Orr, A., Bowen, W. C. & Michalopoulos, G. K. Conditional genetic elimination of hepatocyte growth factor in mice compromises liver regeneration after partial hepatectomy. PLoS One 8, e59836 (2013). 23527275 | 23527275 |
623 | HGF | ARP44317_P050 | Increased expression of angiogenic and inflammatory proteins in the vitreous of patients with ischemic central retinal vein occlusion. PLoS One. 10, e0126859 (2015). 25978399 | 25978399 |
624 | HIF1A | ARP38054_P050 | Organ-specific effects on glycolysis by the dioxin-activated aryl hydrocarbon receptor. PLoS One 2020 12 15 e0243842 33320884 | 33320884 |
625 | HIPK2 | ARP32586_P050 | Choi, D. W. et al. Ubiquitination and degradation of homeodomain-interacting protein kinase 2 by WD40 repeat/SOCS box protein WSB-1. J. Biol. Chem. 283, 4682-9 (2008). 18093972 | 18093972 |
626 | HIPK2 | ARP32586_P050 | Steinmann, S. et al. v-Myc inhibits C/EBPbeta activity by preventing C/EBPbeta-induced phosphorylation of the co-activator p300. Oncogene 28, 2446-55 (2009). 19448669 | 19448669 |
627 | HIPK2 | ARP32586_P050 | Homeodomain interacting protein kinase 2 regulates postnatal development of enteric dopaminergic neurons and glia via BMP signaling. J Neurosci. 31, 13746-57 (2011). 21957238 | 21957238 |
628 | HIPK2 | ARP32586_P050 | Heat shock modulates the subcellular localization, stability, and activity of HIPK2. Biochem. Biophys. Res. Commun. 472, 580-4 (2016). 26972256 | 26972256 |
629 | His | OAEA00010 | P120 catenin potentiates constitutive E-cadherin dimerization at the plasma membrane and regulates trans binding. Curr Biol 3017-3027.e7 31 14 July 2021 | 34019823 |
630 | HK2 | ARP54303_P050 | Targeting hexokinase 2 inhibition promotes radiosensitization in HPV16 E7-induced cervical cancer and suppresses tumor growth. Int J Oncol. 50, 2011-2023 (2017). 28498475 | 28498475 |
631 | HLA-DRB5 | OAAB06426 | Molecular Characteristics of High-Dose Melphalan Associated Oral Mucositis in Patients with Multiple Myeloma: A Gene Expression Study on Human Mucosa. PLoS ONE. 12, e0169286 (2017). 28052121 | 28052121 |
632 | HMGA2 | OAGA00059 | Decoding transcriptomic intra-tumour heterogeneity to guide personalised medicine in ovarian cancer. J Pathol 2019 3 247 305-319 30374975 | 30374975 |
633 | HMOX1 | ARP45222_P050 | Dystrophic muscle improvement in zebrafish via increased heme oxygenase signaling. Hum Mol Genet 2015 15 24 4480-1 26034133 | 26034133 |
634 | HNF-1a | ARP51375_P050 | Scheving, L. A. et al. Epidermal growth factor receptor plays a role in the regulation of liver and plasma lipid levels in adult male mice. Am. J. Physiol. Gastrointest. Liver Physiol. 306, G370-81 (2014). 24407590 | 24407590 |
635 | hnRNP LL | ARP41102_T100 | Liu, G., Lei, L., Yu, J., Kung, S. & Xie, J. Refinement of the spectra of exon usage by combined effects of extracellular stimulus and intracellular factors. Biochim. Biophys. Acta 1839, 537-45 (2014). 24844182 | 24844182 |
636 | HNRNPA1 | ARP40383_T100 | Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones. Genes Dev. 23, 482-95 (2009). 19240134 | 19240134 |
637 | hnRNPA1 | ARP40383_T100 | Li, S. et al. Identification of an aptamer targeting hnRNP A1 by tissue slide-based SELEX. J. Pathol. 218, 327-36 (2009). 19291713 | 19291713 |
638 | hnRNPA1 | ARP40383_T100 | Gonen, N. & Assaraf, Y. G. The obligatory intestinal folate transporter PCFT (SLC46A1) is regulated by nuclear respiratory factor 1. J. Biol. Chem. 285, 33602-13 (2010). 20724482 | 20724482 |
639 | hnRNPA1 | ARP40383_T100 | Stark, M., Bram, E. E., Akerman, M., Mandel-Gutfreund, Y. & Assaraf, Y. G. Heterogeneous nuclear ribonucleoprotein H1/H2-dependent unsplicing of thymidine phosphorylase results in anticancer drug resistance. J. Biol. Chem. 286, 3741-54 (2011). 21068389 | 21068389 |
640 | hnRNPA1 | ARP40383_T100 | Li, S. et al. Aptamer BC15 against heterogeneous nuclear ribonucleoprotein A1 has potential value in diagnosis and therapy of hepatocarcinoma. Nucleic Acid Ther. 22, 391-8 (2012). 23062008 | 23062008 |
641 | hnRNPD | ARP40238_T100 | Kang, X., Chen, W., Kim, R. H., Kang, M. K. & Park, N.-H. Regulation of the hTERT promoter activity by MSH2, the hnRNPs K and D, and GRHL2 in human oral squamous cell carcinoma cells. Oncogene 28, 565-74 (2009). 19015635 | 19015635 |
642 | hnRNPD | ARP40238_T100 | Subramaniam, K., Ooi, L. L. P. J. & Hui, K. M. Transcriptional down-regulation of IGFBP-3 in human hepatocellular carcinoma cells is mediated by the binding of TIA-1 to its AT-rich element in the 3’-untranslated region. Cancer Lett. 297, 259-68 (2010). 20599318 | 20599318 |
643 | HNRNPD | ARP40238_T100 | New compound ChlA-F induces autophagy-dependent anti-cancer effect via upregulating Sestrin-2 in human bladder cancer. Cancer Lett. 436, 38-51 (2018). 30118841 | 30118841 |
644 | HNRNPD | ARP40238_T100 | The inhibitory effect of compound ChlA-F on human bladder cancer cell invasion can be attributed to its blockage of SOX2 protein. Cell Death Differ. 27, 632-645 (2020). 31243344 | 31243344 |
645 | hnRNPH3 | ARP40721_T100 | Larriba, M. J. et al. Novel snail1 target proteins in human colon cancer identified by proteomic analysis. PLoS One 5, e10221 (2010). 20421926 | 20421926 |
646 | HNRNPL | ARP40368_P050 | Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription. Cell. 178, 107-121.e18 (2019). 31251911 | 31251911 |
647 | HNRNPL | ARP40368_P050 | MyoD induced enhancer RNA interacts with hnRNPL to activate target gene transcription during myogenic differentiation. Nat Commun. 10, 5787 (2019). 31857580 | 31857580 |
648 | hnRNPLL | ARP41102_T100 | Yu, J. et al. The heterogeneous nuclear ribonucleoprotein L is an essential component in the Ca2+/calmodulin-dependent protein kinase IV-regulated alternative splicing through cytidine-adenosine repeats. J. Biol. Chem. 284, 1505-13 (2009). 19017650 | 19017650 |
649 | hnRNPLL | ARP41102_T100 | Rajan, P. et al. Proteomic identification of heterogeneous nuclear ribonucleoprotein L as a novel component of SLM/Sam68 Nuclear Bodies. BMC Cell Biol. 10, 82 (2009). 19912651 | 19912651 |
650 | hnRNPLL | ARP41102_T100 | Heyd, F. & Lynch, K. W. Phosphorylation-dependent regulation of PSF by GSK3 controls CD45 alternative splicing. Mol. Cell 40, 126-37 (2010). 20932480 | 20932480 |
651 | HNRNPM | OAAN02059 | The Nuclear SUMO-Targeted Ubiquitin Quality Control Network Regulates the Dynamics of Cytoplasmic Stress Granules. Mol Cell 2020 1 79 54-67.e7 32521226 | 32521226 |
652 | HNRPA3 | ARP41195_T100 | Süss, C. et al. Rapid changes of mRNA-binding protein levels following glucose and 3-isobutyl-1-methylxanthine stimulation of insulinoma INS-1 cells. Mol. Cell. Proteomics 8, 393-408 (2009). 18854578 | 18854578 |
653 | HNRPA3 | ARP41195_T100 | Papadopoulou, C., Patrinou-Georgoula, M. & Guialis, A. Extensive association of HuR with hnRNP proteins within immunoselected hnRNP and mRNP complexes. Biochim. Biophys. Acta 1804, 692-703 (2010). 19931428 | 19931428 |
654 | HNRPAB | ARP41036_T100 | Bubenik, J. L., Ladd, A. N., Gerber, C. A., Budiman, M. E. & Driscoll, D. M. Known turnover and translation regulatory RNA-binding proteins interact with the 3’ UTR of SECIS-binding protein 2. RNA Biol. 6, 73-83 (2009). 19106619 | 19106619 |
655 | HNRPAB | ARP41036_T100 | Taga, Y., Miyoshi, M., Okajima, T., Matsuda, T. & Nadano, D. Identification of heterogeneous nuclear ribonucleoprotein A/B as a cytoplasmic mRNA-binding protein in early involution of the mouse mammary gland. Cell Biochem. Funct. 28, 321-8 (2010). 20517897 | 20517897 |
656 | HNRPF | ARP40565_T100 | White, R. et al. Heterogeneous nuclear ribonucleoprotein (hnRNP) F is a novel component of oligodendroglial RNA transport granules contributing to regulation of myelin basic protein (MBP) synthesis. J. Biol. Chem. 287, 1742-54 (2012). 22128153 | 22128153 |
657 | HNRPH1 | ARP58479_P050 | Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription. Cell 2019 1 178 107-121.e18 31251911 | 31251911 |
658 | HOXA10 | P100767_T100 | Ko, S. Y., Lengyel, E. & Naora, H. The Müllerian HOXA10 gene promotes growth of ovarian surface epithelial cells by stimulating epithelial-stromal interactions. Mol. Cell. Endocrinol. 317, 112-9 (2010). 20036708 | 20036708 |
659 | HOXA5 | ARP31447_P050 | Boucherat, O. et al. Partial functional redundancy between Hoxa5 and Hoxb5 paralog genes during lung morphogenesis. Am. J. Physiol. Lung Cell. Mol. Physiol. 304, L817-30 (2013). 23585229 | 23585229 |
660 | HOXA7 | OAAB10779 | Epigenetic dysregulation of key developmental genes in radiation-induced rat mammary carcinomas. Int J Cancer. 143, 343-354 (2018) 29435983 | 29435983 |
661 | HOXC6 | ARP38484_P050 | Intrinsic control of neuronal diversity and synaptic specificity in a proprioceptive circuit. Elife 2020 NULL 9 NULL 32808924 | 32808924 |
662 | HOXC9 | ARP35813_T100 | Hur, H., Lee, J.-Y., Yun, H. J., Park, B. W. & Kim, M. H. Analysis of HOX Gene Expression Patterns in Human Breast Cancer. Mol. Biotechnol. 56, 64-71 (2014). 23820980 | 23820980 |
663 | HOXC9 | ARP35813_T100 | Homeobox C9 suppresses Beclin1-mediated autophagy in glioblastoma by directly inhibiting the transcription of death-associated protein kinase 1. Neuro-oncology. 18, 819-29 (2016). 26582930 | 26582930 |
664 | HOXD12 | ARP32647_T100 | Illig, R., Fritsch, H. & Schwarzer, C. Spatio-temporal expression of HOX genes in human hindgut development. Dev. Dyn. 242, 53-66 (2013). 23073994 | 23073994 |
665 | HPRT1 | OAAB03804 | Göttle, M. et al. Loss of dopamine phenotype among midbrain neurons in Lesch-Nyhan disease. Ann. Neurol. 76, 95-107 (2014). 24891139 | 24891139 |
666 | HPSE | ARP60766_P050 | High glucose facilitated endothelial heparanase transfer to the cardiomyocyte modifies its cell death signature. Cardiovasc Res. 112, 656-668 (2016). 27979811 | 27979811 |
667 | HPSE | ARP60766_P050 | The exostosin family of glycosyltransferases: mRNA expression profiles and heparan sulphate structure in human breast carcinoma cell lines. Biosci Rep. 38, (2018). 30054430 | 30054430 |
668 | HRH1 | OAEB00846 | Localization of histamine (H1, H2, H3 and H4) receptors in mouse inner ear. Acta Otolaryngol. 136, 537-44 (2016). 26854127 | 26854127 |
669 | HRP | OAIA00498 | Bioaffinity-based surface immobilization of antibodies to capture endothelial colony-forming cells. PLoS One e0269316 17 8 August 2022 | 36040884 |
670 | HSD11B1 | ARP45714_P050 | Lei, K. et al. Progesterone acts via the nuclear glucocorticoid receptor to suppress IL-1beta-induced COX-2 expression in human term myometrial cells. PLoS One 7, e50167 (2012). 23209664 | 23209664 |
671 | HSD11B1 | ARP45714_P050 | Kuroda, K. et al. Induction of 11beta-HSD 1 and activation of distinct mineralocorticoid receptor- and glucocorticoid receptor-dependent gene networks in decidualizing human endometrial stromal cells. Mol. Endocrinol. 27, 192-202 (2013). 23275455 | 23275455 |
672 | HSD17B13 | OAAN01691 | Splice variant rs72613567 prevents worst histologic outcomes in patients with nonalcoholic fatty liver disease. J Lipid Res. 60, 176-185 (2019). 30323112 | 30323112 |
673 | HSD17B3 | OAAB06112 | Bertin, J., Dury, A. Y., Ouellet, J., Pelletier, G. & Labrie, F. Localization of the androgen-synthesizing enzymes, androgen receptor, and sex steroids in the vagina: possible implications for the treatment of postmenopausal sexual dysfunction. J. Sex. Med. 11, 1949-61 (2014). 24919541 | 24919541 |
674 | HSD17B6 | ARP41529_T100 | Mohler, J. L. et al. Activation of the androgen receptor by intratumoral bioconversion of androstanediol to dihydrotestosterone in prostate cancer. Cancer Res. 71, 1486-96 (2011). 21303972 | 21303972 |
675 | HSD17B6 | ARP41529_T100 | Muthusamy, S. et al. Estrogen receptor beta and 17beta-hydroxysteroid dehydrogenase type 6, a growth regulatory pathway that is lost in prostate cancer. Proc. Natl. Acad. Sci. U. S. A. 108, 20090-4 (2011). 22114194 | 22114194 |
676 | HSD3B2 | OAGA02009 | NNT is a key regulator of adrenal redox homeostasis and steroidogenesis in male mice. J Endocrinol. 236, 13-28 (2018). 29046340 | 29046340 |
677 | HSD3B2 | OAGA02009 | Fei Wang, et al. Roles of Sialic Acid, AXL, and MER Receptor Tyrosine Kinases in Mumps Virus Infection of Mouse Sertoli and Leydig Cells. 1292 (2020). 32695074 | 32695074 |
678 | HSP90AA1 | OAED00192 | Heat Shock Alters the Proteomic Profile of Equine Mesenchymal Stem Cells. Int J Mol Sci 2022 13 23 NULL 35806237 | 35806237 |
679 | HSPA8 | ARP48445_P050 | Hsc70 Ameliorates the Vesicle Recycling Defects Caused by Excess a-Synuclein at Synapses. Eneuro. 7, (2020). 31941659 | 31941659 |
680 | HSPA8 | ARP48445_P050 | Identification of Synaptic DGKθ Interactors That Stimulate DGKθ Activity. Front Synaptic Neurosci 2022 NULL 14 855673 35573662 | 35573662 |
681 | HSPB1 | ARP30177_T100 | Narjoz, C. et al. Genomic consequences of cytochrome P450 2C9 overexpression in human hepatoma cells. Chem. Res. Toxicol. 22, 779-87 (2009). 19445531 | 19445531 |
682 | HSPB1 | ARP30177_T100 | Heat Shock Protein 27 is down-regulated in Ballooned Hepatocytes of Patients with Nonalcoholic Steatohepatitis (NASH). Sci Rep. 6, 22528 (2016). 26935030 | 26935030 |
683 | HSPH1 | ARP52217_P050 | Expression and function of HSP110 family in mouse testis after vasectomy. Asian J. Androl. (2016). 26952955 | 26952955 |
684 | HTR3A | AVARP13046_P050 | Rinaldi, A. et al. Serotonin receptor 3A expression in normal and neoplastic B cells. Pathobiology 77, 129-35 (2010). 20516728 | 20516728 |
685 | HVCN1 | OAPB01154 | Genetic variation of staphylococcal LukAB toxin determines receptor tropism. Nat Microbiol. 6, 731-745 (2021). 33875847 | 33875847 |
686 | IDH3A | ARP42237_T100 | Lin, C.-C. et al. Loss of the respiratory enzyme citrate synthase directly links the Warburg effect to tumor malignancy. Sci. Rep. 2, 785 (2012). 23139858 | 23139858 |
687 | IDH3A | ARP42237_T100 | Alteration of isocitrate dehydrogenase following acute ischemic injury as a means to improve cellular energetic status in neuroadaptation. CNS Neurol Disord Drug Targets. 12, 849-60 (2013). 23469839 | 23469839 |
688 | IDO2 | OAAB08672 | Molecular imaging correlates of tryptophan metabolism via the kynurenine pathway in human meningiomas. Neuro Oncol. 17, 1284-92 (2015). 26092774 | 26092774 |
689 | IDO2 | OAAB08672 | Tryptophan PET Imaging of the Kynurenine Pathway in Patient-Derived Xenograft Models of Glioblastoma. Mol Imaging. 15, (2016). 27151136 | 27151136 |
690 | IDO2 | OAAB08672 | Investigation of the aryl hydrocarbon receptor and the intrinsic tumoral component of the kynurenine pathway of tryptophan metabolism in primary brain tumors. J Neurooncol. 139, 239-249 (2018). 29667084 | 29667084 |
691 | IER2 | ARP34401_P050 | IER2-induced senescence drives melanoma invasion through osteopontin. Oncogene. 40, 6494-6512 (2021). 34611309 | 34611309 |
692 | IFIT3 | ARP46034_P050 | Gene Expression Profiling Identifies Interferon Signalling Molecules and IGFBP3 in Human Degenerative Annulus Fibrosus. Sci Rep. 5, 15662 (2015). 26489762 | 26489762 |
693 | IFNB1 | OAAB05131 | Sanderson, S. D. et al. Innate immune induction and influenza protection elicited by a response-selective agonist of human C5a. PLoS One 7, e40303 (2012). 22792270 | 22792270 |
694 | IFNLR1 | ARP48070_P050 | Pseudorabies Virus Inhibits Type I and Type III Interferon-Induced Signaling via Proteasomal Degradation of Janus Kinases. J Virol 2021 20 95 e0079321 34379505 | 34379505 |
695 | IGF1R | AVARP00004_P050 | Kubota, T. et al. Insulin-like growth factor-1 receptor in mature osteoblasts is required for periosteal bone formation induced by reloading. Acta Astronaut. 92, 73-78 (2013). 23976802 | 23976802 |
696 | IGF1R | AVARP00004_P050 | Roles of progesterone receptor membrane component 1 and membrane progestin receptor alpha in regulation of zebrafish oocyte maturation. Gen Comp Endocrinol. 263, 51-61 (2018). 29649418 | 29649418 |
697 | IGF2 | OAAB07463 | Modulation of IGF2 Expression in the Murine Thymus and Thymic Epithelial Cells Following Coxsackievirus-B4 Infection. Microorganisms. 9 (2021) 33672010 | 33672010 |
698 | IGF2BP1 | ARP40658_P050 | Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation. Mol Cell. 74, 701-712.e9 (2019). 30948266 | 30948266 |
699 | IGFBP4 | ARP45685_P050 | Shi, Z., Chiang, C.-I., Mistretta, T.-A., Major, A. & Mori-Akiyama, Y. SOX9 directly regulates IGFBP-4 in the intestinal epithelium. Am. J. Physiol. Gastrointest. Liver Physiol. 305, G74-83 (2013). 23660500 | 23660500 |
700 | IGG | ASP00001 | Effects of Ethanol on the Expression Level of Various BDNF mRNA Isoforms and Their Encoded Protein in the Hippocampus of Adult and Embryonic Rats. Int J Mol Sci. 16, 30422-37 (2015). 26703578 | 26703578 |
701 | IGG | ASP00001 | Differential Effects of Resveratrol on the Expression of Brain-Derived Neurotrophic Factor Transcripts and Protein in the Hippocampus of Rat Brain. Iran J Med Sci. 42, 32-39 (2017). 28293048 | 28293048 |
702 | IgG | ASP00001 | Divergent Hemogen genes of teleosts and mammals share conserved roles in erythropoiesis: analysis using transgenic and mutant zebrafish. Biol Open. 7, (2018). 30097520 | 30097520 |
703 | IgG | ASP00001 | Silencing of ribonucleotide reductase subunit M1 potentiates the antitumor activity of gemcitabine in resistant cancer cells. Cancer Biol Ther. 13, 908-14 (2012) 22785206 | 22785206 |
704 | IgG | OARA04973 | Divergent Hemogen genes of teleosts and mammals share conserved roles in erythropoiesis: analysis using transgenic and mutant zebrafish. Biol Open. 7, (2018). 30097520 | 30097520 |
705 | IgG-HRP | ASP00001 | Chung, W.-G., Sandoval, M. A., Sloat, B. R., Lansakara-P, D. S. P. & Cui, Z. Stearoyl gemcitabine nanoparticles overcome resistance related to the over-expression of ribonucleotide reductase subunit M1. J. Control. Release 157, 132-40 (2012). 21851843 | 21851843 |
706 | IGHG2C | OASB01582 | Influenza virus infection expands the breadth of antibody responses through IL-4 signalling in B cells. Nat Commun. 12, 3789 (2021) 34145279 | 34145279 |
707 | IHH | ARP45230_T100 | Mirza, R. et al. 3beta-Hydroxysterol-Delta24 reductase plays an important role in long bone growth by protecting chondrocytes from reactive oxygen species. J. Bone Miner. Metab. 30, 144-53 (2012). 21845517 | 21845517 |
708 | IL1B | ARP54323_P050 | Wang, F. et al. Shigella flexneri T3SS effector IpaH4.5 modulates the host inflammatory response via interaction with NF-κB p65 protein. Cell. Microbiol. 15, 474-85 (2013). 23083102 | 23083102 |
709 | IL1B | ARP54323_P050 | 1a,25-dihydroxyvitamin D3 and resolvin D1 retune the balance between amyloid-β phagocytosis and inflammation in Alzheimer's disease patients. J Alzheimers Dis. 34, 155-70 (2012). 23186989 | 23186989 |
710 | IL1B | ARP54323_P050 | Circulating microparticles enhanced rat vascular wall remodeling following endothelial denudation. Am J Transl Res. 8, 4511-4522 (2016). 27904658 | 27904658 |
711 | IL-1b | OAPA00159 | Chronic rapamycin treatment decreases hepatic IL-6 protein, but increases autophagy markers as a protective effect against the overtraining-induced tissue damage. Clin Exp Pharmacol Physiol 893-902 49 8 August 2022 | 35637552 |
712 | IL25 | OAAB10988 | Expression of IL-25, IL-33, and Thymic Stromal Lymphopoietin in Nasal Polyp Gland Duct Epithelium in Patients With Chronic Rhinosinusitis. Am J Rhinol Allergy. 33, 378-387 (2019). 30873846 | 30873846 |
713 | ILF2 | ARP35731_T100 | Jiang, D., Zhou, Y., Moxley, R. A. & Jarrett, H. W. Purification and identification of positive regulators binding to a novel element in the c-Jun promoter. Biochemistry 47, 9318-34 (2008). 18690718 | 18690718 |
714 | ILF2 | ARP35731_T100 | Yamauchi, T. et al. Sepantronium bromide (YM155) induces disruption of the ILF3/p54(nrb) complex, which is required for survivin expression. Biochem. Biophys. Res. Commun. 425, 711-6 (2012). 22842455 | 22842455 |
715 | IQCK | ARP53134_P050 | Novel Alzheimer risk factor IQ motif containing protein K is abundantly expressed in the brain and is markedly increased in patients with Alzheimer's disease. Front Cell Neurosci 954071 16 NULL August 2022 | 35928571 |
716 | IRAK1 | OABF01186 | Afghanistan Particulate Matter Enhances Pro-Inflammatory Responses in IL-13-Exposed Human Airway Epithelium via TLR2 Signaling. Toxicol Sci. 166, 345-353 (2018). 30169750 | 30169750 |
717 | IRF3 | OAAF00779 | Dong, X.-Y. et al. Classical swine fever virus triggers RIG-I and MDA5-dependent signaling pathway to IRF-3 and NF-κB activation to promote secretion of interferon and inflammatory cytokines in porcine alveolar macrophages. Virol. J. 10, 286 (2013). 24034559 | 24034559 |
718 | IRF6 | ARP31995_P050 | Iwata, J. et al. Smad4-Irf6 genetic interaction and TGFbeta-mediated IRF6 signaling cascade are crucial for palatal fusion in mice. Development 140, 1220-30 (2013). 23406900 | 23406900 |
719 | ISGF3G | ARP31200_P050 | Bidwell, B. N. et al. Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape. Nat. Med. 18, 1224-31 (2012). 22820642 | 22820642 |
720 | JHDM2A | ARP32911_T100 | Zhou, X., Sun, H., Ellen, T. P., Chen, H. & Costa, M. Arsenite alters global histone H3 methylation. Carcinogenesis 29, 1831-6 (2008). 18321869 | 18321869 |
721 | JOSD3 | OAAB03009 | Expression Atlas of the Deubiquitinating Enzymes in the Adult Mouse Retina, Their Evolutionary Diversification and Phenotypic Roles. PLoS ONE. 11, e0150364 (2016). 26934049 | 26934049 |
722 | JUN | P100911_P050 | Russo, R. et al. The newly characterized Pl-jun is specifically expressed in skeletogenic cells of the Paracentrotus lividus sea urchin embryo. FEBS J. 281, 3828-43 (2014). 25040505 | 25040505 |
723 | KCNAB2 | ARP37678_T100 | Metabolic regulation of Kv channels and cardiac repolarization by Kvβ2 subunits. J Mol Cell Cardiol. 137, 93-106 (2019). 31639389 | 31639389 |
724 | KCNK9 | ARP35260_P050 | Epigenetic Dysregulation of KCNK9 Imprinting and Triple-Negative Breast Cancer. Cancers (Basel) 2021 23 13 NULL 34885139 | 34885139 |
725 | KCNMA1 | ARP35092_P050 | Molecular phenotyping of the surfaceome of migratory chondroprogenitors and mesenchymal stem cells using biotinylation, glycocapture and quantitative LC-MS/MS proteomic analysis. Sci Rep. 9, 9018 (2019). 31227739 | 31227739 |
726 | KCNN2 | ARP35094_T100 | Chakroborty, S. et al. Early presynaptic and postsynaptic calcium signaling abnormalities mask underlying synaptic depression in presymptomatic Alzheimer’s disease mice. J. Neurosci. 32, 8341-53 (2012). 22699914 | 22699914 |
727 | KCNN2 | ARP35439_P050 | Chakroborty, S. et al. Early presynaptic and postsynaptic calcium signaling abnormalities mask underlying synaptic depression in presymptomatic Alzheimer’s disease mice. J. Neurosci. 32, 8341-53 (2012). 22699914 | 22699914 |
728 | KCNQ1 | ARP34924_P050 | Zhou, S. et al. Antiarrhythmic effects of beta3-adrenergic receptor stimulation in a canine model of ventricular tachycardia. Heart Rhythm 5, 289-97 (2008). 18242556 | 18242556 |
729 | KCNQ2 | ARP35459_T100 | Zhang, H. et al. Membrane microdomain determines the specificity of receptor-mediated modulation of Kv7/M potassium currents. Neuroscience 254, 70-9 (2013). 24036375 | 24036375 |
730 | KCNQ2 | ARP35459_T100 | Functional responses of the hippocampus to hyperexcitability depend on directed, neuron-specific KCNQ2 K+ channel plasticity. Hippocampus. 30, 435-455 (2020) 31621989 | 31621989 |
731 | KCNQ3 | OAAF00246 | Kv7 channels are upregulated during striatal neuron development and promote maturation of human iPSC-derived neurons. Pflugers Arch. 470, 1359-1376 (2018). 29797067 | 29797067 |
732 | KCTD10 | OAAB09706 | Wang, Y. et al. KCTD10 interacts with proliferating cell nuclear antigen and its down-regulation could inhibit cell proliferation. J. Cell. Biochem. 106, 409-13 (2009). 19125419 | 19125419 |
733 | KDM6B | ARP40102_T100 | Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS. Genes Dev 2009 10 23 1177-82 19451218 | 19451218 |
734 | KDR | OAEC00429 | Silence of lncRNA UCA1 Represses the Growth and Tube Formation of Human Microvascular Endothelial Cells Through miR-195. Cell Physiol Biochem. 49, 1499-1511 (2018). 30205377 | 30205377 |
735 | KEAP1 | ARP34728_T100 | Protein levels in Keap1-Nrf2 system in human failing heart. Int. J. Cardiol. 225, 62-64 (2016). 27710805 | 27710805 |
736 | KEAP1 | OACD04962 | Virus Infection Induces Keap1 Binding to Cytokine Genes, Which Recruits NF-κB p50 and G9a-GLP and Represses Cytokine Transcription. J Immunol 2021 5 207 1437-1447 34400522 | 34400522 |
737 | KHSRP | ARP40474_P050 | Ahn, Y.-H. et al. Electrophilic tuning of the chemoprotective natural product sulforaphane. Proc. Natl. Acad. Sci. U. S. A. 107, 9590-5 (2010). 20439747 | 20439747 |
738 | KIAA0317 | ARP44874_P050 | Ubiquitin E3 ligase FIEL1 regulates fibrotic lung injury through SUMO-E3 ligase PIAS4. J Exp Med. 2016 May 30; 213(6): 1029-1046. 27162139 | 27162139 |
739 | KIF5B | ARP33903_P050 | Turner, L. S. et al. Autophagy is increased in prostate cancer cells overexpressing acid ceramidase and enhances resistance to C6 ceramide. Prostate Cancer Prostatic Dis. 14, 30-7 (2011). 21116286 | 21116286 |
740 | KIM1 | OABB00585 | Hydrogen Sulfide Treatment Mitigates Renal Allograft Ischemia-Reperfusion Injury during Cold Storage and Improves Early Transplant Kidney Function and Survival Following Allogeneic Renal Transplantation. J. Urol. 194, 1806-15 (2015). 26239336 | 26239336 |
741 | KIT | OAEE00056 | Expression of Luminal Progenitor Marker CD117 in the Human Breast Gland. J Histochem Cytochem. 66, 879-888 (2018). 30004288 | 30004288 |
742 | KLB | ARP53325_P050 | Intestinal epithelial β Klotho is a critical protective factor in alcohol-induced intestinal barrier dysfunction and liver injury. EBioMedicine 104181 82 NULL August 2022 | 35908416 |
743 | KLF2 | ARP32760_P050 | Yamada, T., Park, C. S., Mamonkin, M. & Lacorazza, H. D. Transcription factor ELF4 controls the proliferation and homing of CD8+ T cells via the Krüppel-like factors KLF4 and KLF2. Nat. Immunol. 10, 618-26 (2009). 19412182 | 19412182 |
744 | KLF4 | ARP38430_P050 | BMP- and TGFβ-signaling regulate the formation of Müller glia-derived progenitor cells in the avian retina. Glia. 65, 1640-1655 (2017). 28703293 | 28703293 |
745 | Klf4 | OAAD00376 | Luz-Madrigal, A. et al. Reprogramming of the chick retinal pigmented epithelium after retinal injury. BMC Biol. 12, 28 (2014). 24742279 | 24742279 |
746 | KLF4 | ARP38430_P050 | Retinoic Acid-Signaling Regulates the Proliferative and Neurogenic Capacity of Müller Glia-Derived Progenitor Cells in the Avian Retina. Stem Cells 2018 3 36 392-405 29193451 | 29193451 |
747 | KLF8 | ARP31533_P050 | Fu, W.-J. et al. Small interference RNA targeting Krüppel-like factor 8 inhibits the renal carcinoma 786-0 cells growth in vitro and in vivo. J. Cancer Res. Clin. Oncol. 136, 1255-65 (2010). 20182889 | 20182889 |
748 | KLF8 | ARP31533_P050 | Li, J.-C. et al. Up-regulation of Krüppel-like factor 8 promotes tumor invasion and indicates poor prognosis for hepatocellular carcinoma. Gastroenterology 139, 2146-2157.e12 (2010). 20728449 | 20728449 |
749 | KLF8 | ARP31533_P050 | Han, S. et al. Krüppel‑like factor expression and correlation with FAK, MMP‑9 and E‑cadherin expression in hepatocellular carcinoma. Mol. Med. Rep. 8, 81-8 (2013). 23670717 | 23670717 |
750 | KLF8 | ARP31533_P050 | KLF8 promotes tumorigenesis, invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2. Oncotarget. 6, 25402-17 (2015). 26320172 | 26320172 |
751 | KMO | OAAB05255 | Kynurenine Monooxygenase Expression and Activity in Human Astrocytomas. Cells. 10, NULL (2021) 34440798 | 34440798 |
752 | L1CAM | OAAB11621 | Increased plasmin-mediated proteolysis of L1CAM in a mouse model of idiopathic normal pressure hydrocephalus. Proc Natl Acad Sci U S A 2021 33 118 NULL 34380733 | 34380733 |
753 | LAMP1 | OAAB13754 | Restoring diabetes-induced autophagic flux arrest in ischemic/reperfused heart by ADIPOR (adiponectin receptor) activation involves both AMPK-dependent and AMPK-independent signaling. Autophagy. 13, 1855-1869 (2017). 28825851 | 28825851 |
754 | LAMP2 | OAAB06711 | Lysosomes, autophagosomes and Alzheimer pathology in dementia with Lewy body disease. Neuropathology NULL NULL NULL May 2018 | 29748975 |
755 | LBP | ARP41546_P050 | Seasonal heat load is more potent than the degree of body weight loss in dysregulating immune function by reducing white blood cell populations and increasing inflammation in Holstein dairy cows. J Dairy Sci. 103, 10809-10822 (2020). 32896401 | 32896401 |
756 | LC3-II | OAAB13483 | NKCT1 (purified Naja kaouthia protein toxin) conjugated gold nanoparticles induced Akt/mTOR inactivation mediated autophagic and caspase 3 activated apoptotic cell death in leukemic cell. Toxicon. 121, 86-97 (2016). 27527270 | 27527270 |
757 | LEP | ARP41697_P050 | Leptin in the canine uterus and placenta: possible implications in pregnancy. Reprod Biol Endocrinol. 13, 13 (2015). 25871422 | 25871422 |
758 | LEP | ARP41698_P050 | Proteomic Analysis of Plasma Reveals Fat Mass Influences Cancer-Related Pathways in Healthy Humans Fed Controlled Diets Differing in Glycemic Load. Cancer Prev Res (Phila). 12, 567-578 (2019). 31266826 | 31266826 |
759 | LEPTIN | ARP41697_P050 | Different expression of leptin and IGF1 in the adult and prepubertal testis in dogs. Reprod. Domest. Anim. 52 Suppl 2, 187-192 (2017). 28101891 | 28101891 |
760 | LGALS3 | ARP54688_P050 | Guha, P. et al. Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, a9 nicotinic acetylcholine receptor and STAT3. Breast Cancer Res. Treat. 145, 5-22 (2014). 24668500 | 24668500 |
761 | LHX6 | ARP32553_T100 | Genome-wide screening for deubiquitinase subfamily identifies ubiquitin-specific protease 49 as a novel regulator of odontogenesis. Cell Death Differ 2022 NULL NULL NULL 35273362 | 35273362 |
762 | LIPE | OAAF00742 | Shao-Wei Lu, et al. IL-20 antagonist suppresses PD-L1 expression and prolongs survival in pancreatic cancer models. 4611 (2020). 32929072 | 32929072 |
763 | LMNB2 | ARP46356_P050 | The nucleoporin Nup153 regulates embryonic stem cell pluripotency through gene silencing. Genes Dev. 29, 1224-38 (2015). 26080816 | 26080816 |
764 | LOC100009097 | OASB00822 | Two Faces of CwlM, an Essential PknB Substrate, in Mycobacterium tuberculosis. Cell Rep. 25, 57-67.e5 (2018). 30282038 | 30282038 |
765 | LOX1 | OACD05298 | Molecular mechanism of statin-mediated LOX-1 inhibition. Cell Cycle. 14, 1583-95 (2015). 25950192 | 25950192 |
766 | LOX15 | OAAB04977 | Starowicz, K. et al. Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism. PLoS One 8, e60040 (2013). 23573230 | 23573230 |
767 | LRP1 | ARP58562_P050 | Behl, M., Zhang, Y., Monnot, A. D., Jiang, W. & Zheng, W. Increased beta-amyloid levels in the choroid plexus following lead exposure and the involvement of low-density lipoprotein receptor protein-1. Toxicol. Appl. Pharmacol. 240, 245-54 (2009). 19501112 | 19501112 |
768 | LRP1 | ARP58562_P050 | Gu, H. et al. Lead exposure increases levels of beta-amyloid in the brain and CSF and inhibits LRP1 expression in APP transgenic mice. Neurosci. Lett. 490, 16-20 (2011). 21167913 | 21167913 |
769 | LRP1 | ARP58562_P050 | Hentschke, M. R. et al. Is the atherosclerotic phenotype of preeclamptic placentas due to altered lipoprotein concentrations and placental lipoprotein receptors? Role of a small-for-gestational-age phenotype. J. Lipid Res. 54, 2658-64 (2013). 23898049 | 23898049 |
770 | MAFA | ARP47760_P050 | Molecular and genetic regulation of pig pancreatic islet cell development. Development 2020 NULL NULL NULL 34004773 | 34004773 |
771 | MAP1LC3A | ARP51335_P050 | Icariside II, a phosphodiesterase 5 inhibitor, attenuates cerebral ischaemia/reperfusion injury by inhibiting glycogen synthase kinase-3β-mediated activation of autophagy. Br J Pharmacol. 177, 1434-1452 (2020). 31658364 | 31658364 |
772 | MAP2K | ARP42065_P050 | Dual Role of Insulin in Spexin Regulation: Functional Link Between Food Intake and Spexin Expression in a Fish Model. Endocrinology 2017 3 158 560-577 28359089 | 28359089 |
773 | MAP2K7 | OAAF05547 | Hepatocyte TRAF3 promotes liver steatosis and systemic insulin resistance through targeting TAK1-dependent signalling. Nat Commun. 7, 10592 (2016). 26882989 | 26882989 |
774 | MAP2K7 | OAAF05547 | Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates. Nat. Med. 23, 439-449 (2017). 28218919 | 28218919 |
775 | MAP2K7 | OAAF05547 | Receptor-interacting protein kinase 2 (RIPK2) stabilizes c-Myc and is a therapeutic target in prostate cancer metastasis. Nat Commun 2022 1 13 669 35115556 | 35115556 |
776 | MAP3K7IP2 | ARP32402_P050 | Thienpont, B. et al. Haploinsufficiency of TAB2 causes congenital heart defects in humans. Am. J. Hum. Genet. 86, 839-49 (2010). 20493459 | 20493459 |
777 | MARVELD3 | ARP44715_P050 | α-Synuclein pre-formed fibrils impair tight junction protein expression without affecting cerebral endothelial cell function. Exp Neurol. 285, 72-81 (2016) 27632900 | 27632900 |
778 | MATR3 | ARP40922_T100 | Valencia, C. A., Ju, W. & Liu, R. Matrin 3 is a Ca2+/calmodulin-binding protein cleaved by caspases. Biochem. Biophys. Res. Commun. 361, 281-6 (2007). 17658460 | 17658460 |
779 | MATR3 | ARP40922_T100 | Kula, A. et al. Characterization of the HIV-1 RNA associated proteome identifies Matrin 3 as a nuclear cofactor of Rev function. Retrovirology 8, 60 (2011). 21771346 | 21771346 |
780 | MATR3 | ARP40922_T100 | Kula, A., Gharu, L. & Marcello, A. HIV-1 pre-mRNA commitment to Rev mediated export through PSF and Matrin 3. Virology 435, 329-40 (2013). 23158102 | 23158102 |
781 | MAZ | ARP38146_P050 | Smits, M. et al. Myc-associated zinc finger protein (MAZ) is regulated by miR-125b and mediates VEGF-induced angiogenesis in glioblastoma. FASEB J. 26, 2639-47 (2012). 22415301 | 22415301 |
782 | MBD2 | ARP32485_P050 | Jungwirth, M., Dear, M. L., Brown, P., Holbrook, K. & Goodchild, R. Relative tissue expression of homologous torsinB correlates with the neuronal specific importance of DYT1 dystonia-associated torsinA. Hum. Mol. Genet. 19, 888-900 (2010). 20034025 | 20034025 |
783 | MBNL1 | ARP41227_P050 | Muscleblind-like 1 is required for normal heart valve development in vivo. BMC Dev. Biol. 15, 36 (2015). 26472242 | 26472242 |
784 | MBP | OABB00147 | Cerebral Apolipoprotein-D Is Hypoglycosylated Compared to Peripheral Tissues and Is Variably Expressed in Mouse and Human Brain Regions. PLoS ONE. 11, e0148238 (2016). 26829325 | 26829325 |
785 | mCherry-Tag | OAAF04756 | Monocarboxylate Transporter 4 in Cancer-Associated Fibroblasts Is a Driver of Aggressiveness in Aerodigestive Tract Cancers. Front Oncol 2022 NULL 12 906494 35814364 | 35814364 |
786 | MCM8 | ARP36668_P050 | Ono, A. et al. Overexpression of heat shock protein 27 in squamous cell carcinoma of the uterine cervix: a proteomic analysis using archival formalin-fixed, paraffin-embedded tissues. Hum. Pathol. 40, 41-9 (2009). 18755499 | 18755499 |
787 | MDH2 | ARP48286_T100 | 2-D DIGE analysis of the mitochondrial proteome from human skeletal muscle reveals time course-dependent remodelling in response to 14 consecutive days of endurance exercise training. Proteomics 2011 8 11 1413-28 21360670 | 21360670 |
788 | MED17 | ARP34192_P050 | DSIF and NELF interact with Integrator to specify the correct post-transcriptional fate of snRNA genes. Nat Commun. 5, 4263 (2014). 24968874 | 24968874 |
789 | MED17 | ARP34192_P050 | Hepatic TRAP80 selectively regulates lipogenic activity of liver X receptor. J Clin Invest. 125, 183-93 (2015). 25437875 | 25437875 |
790 | MED25 | OAAB00209 | Synergistic activation of Arg1 gene by retinoic acid and IL-4 involves chromatin remodeling for transcription initiation and elongation coupling. Nucleic Acids Res. 44, 7568-79 (2016). 27166374 | 27166374 |
791 | MEF2C | OAGA02537 | MEF2C regulates osteoclastogenesis and pathologic bone resorption via c-FOS. Bone Res. 9, 4 (2021). 33424022 | 33424022 |
792 | MEIS2 | ARP34684_T100 | Jackson, B. et al. TALE homeodomain proteins regulate site-specific terminal differentiation, LCE genes and epidermal barrier. J. Cell Sci. 124, 1681-90 (2011). 21511732 | 21511732 |
793 | MER | OAAF00456 | Normalization of TAM post-receptor signaling reveals a cell invasive signature for Axl tyrosine kinase. Cell Commun. Signal. 14, 19 (2016). 27595981 | 27595981 |
794 | METTL3 | ARP39390_T100 | N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation. Dev Cell. 55, 737-753.e7 (2020). 33220174 | 33220174 |
795 | MFN2 | ARP42420_P050 | Hepatitis C virus NS5A protein cooperates with phosphatidylinositol 4-kinase IIIa to induce mitochondrial fragmentation. Sci Rep. 6, 23464 (2016). 27010100 | 27010100 |
796 | Mif4GD | ARP40950_T100 | Okada, K. et al. Expression analysis of MIF4GD in the rat testis. J. Reprod. Dev. 57, 256-61 (2011). 21157122 | 21157122 |
797 | MINOS1 | ARP44801_P050 | QIL1 mutation causes MICOS disassembly and early onset fatal mitochondrial encephalopathy with liver disease. Elife 2016 NULL 5 NULL 27623147 | 27623147 |
798 | MIWI | ARP41339_P050 | Tex19 paralogs are new members of the piRNA pathway controlling retrotransposon suppression. J. Cell. Sci. 130, 1463-1474 (2017). 28254886 | 28254886 |
799 | MKI67 | OAAF01852 | Mesenchymal stem cells increase expression of heme oxygenase-1 leading to anti-inflammatory activity in treatment of acute liver failure. Stem Cell Res Ther. 8, 70 (2017). 28320485 | 28320485 |
800 | MMP10 | OAAF01865 | Inside the Thrombus: Association of Hemostatic Parameters With Outcomes in Large Vessel Stroke Patients. Front Neurol. 12, 599498 (2021) 33692737 | 33692737 |
801 | MMP10 | OAAI00209 | Matrix Metalloproteinase 10 Contributes to Choroidal Neovascularisation. Biomedicines NULL 10 7 June 2022 | 35884862 |
802 | MMP13 | ARP56350_P050 | Alleviation of Murine Osteoarthritis by Cartilage-Specific Deletion of IκBζ. Arthritis Rheumatol 1440-1449 70 9 September 2018 | 29604191 |
803 | MMP2 | AVARP20016_T100 | TNF-a promotes breast cancer cell migration and enhances the concentration of membrane-associated proteases in lipid rafts. Cell Oncol (Dordr). 39, 353-63 (2016). 27042827 | 27042827 |
804 | MMP2 | AVARP20016_T100 | Developmental Programming: Gestational Exposure to Excess Testosterone Alters Expression of Ovarian Matrix Metalloproteases and Their Target Proteins. Reprod Sci. 1933719117697127 (2017). 28299992 | 28299992 |
805 | MMP3 | ARP42042_P050 | Clusterin secretion is attenuated by the proinflammatory cytokines interleukin-1β and tumor necrosis factor-α in models of cartilage degradation. J Orthop Res. (2020) 32725904 | 32725904 |
806 | MMP3 | OAAF01874 | Expression of matrix metalloproteinases and components of the endocannabinoid system in the knee joint are associated with biphasic pain progression in a rat model of osteoarthritis. J Pain Res. 10, 1973-1989 (2017). 28860852 | 28860852 |
807 | MMP9 | ARP33090_T100 | Gotschy, A. et al. Local arterial stiffening assessed by MRI precedes atherosclerotic plaque formation. Circ. Cardiovasc. Imaging 6, 916-23 (2013). 24100044 | 24100044 |
808 | MMP9 | ARP33090_T100 | Li, L. et al. DLK1 promotes lung cancer cell invasion through upregulation of MMP9 expression depending on Notch signaling. PLoS One 9, e91509 (2014). 24621612 | 24621612 |
809 | MMP9 | ARP33090_T100 | Developmental Programming: Gestational Exposure to Excess Testosterone Alters Expression of Ovarian Matrix Metalloproteases and Their Target Proteins. Reprod Sci. 1933719117697127 (2017). 28299992 | 28299992 |
810 | MMP-9 | ARP33090_T100 | Zhang, J., Jiang, W. & Zuo, Z. Pyrrolidine dithiocarbamate attenuates surgery-induced neuroinflammation and cognitive dysfunction possibly via inhibition of nuclear factor κB. Neuroscience 261, 1-10 (2014). 24365462 | 24365462 |
811 | MMP-9 | ARP33090_T100 | Deng, J., Zhang, J., Feng, C., Xiong, L. & Zuo, Z. Critical role of matrix metalloprotease-9 in chronic high fat diet-induced cerebral vascular remodelling and increase of ischaemic brain injury in mice. Cardiovasc. Res. 103, 473-84 (2014). 24935427 | 24935427 |
812 | MMP-9 | ARP33090_T100 | Immunohistochemical determination of the extracellular matrix modulation in a rat model of choline-deprived myocardium: the effects of carnitine. Fundam Clin Pharmacol. 30, 47-57 (2016). 26501493 | 26501493 |
813 | MOG | OAPA00088 | Oral Tolerance Induction in Experimental Autoimmune Encephalomyelitis with Candida utilis Expressing the Immunogenic MOG35-55 Peptide. PLoS ONE. 11, e0155082 (2016). 27159446 | 27159446 |
814 | MRAP | OAAB06581 | Exome-based investigation of the genetic basis of human pigmentary glaucoma. BMC Genomics. 22, 477 (2021) 34174832 | 34174832 |
815 | MRC1 | OASA05048 | Cathepsin B-Mediated Activation of Trypsinogen in Endocytosing Macrophages Increases Severity of Pancreatitis in Mice. Gastroenterology. 154, 704-718.e10 (2018). 29079517 | 29079517 |
816 | MRC1 | OASA05048 | NLRP3 Inflammasome Regulates Development of Systemic Inflammatory Response and Compensatory Anti-Inflammatory Response Syndromes in Mice With Acute Pancreatitis. Gastroenterology. 158, 253-269.e14 (2020). 31593700 | 31593700 |
817 | MRG15 | ARP32832_T100 | Xie, L. et al. KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription. EMBO J. 30, 1473-84 (2011). 21448134 | 21448134 |
818 | MRPS15 | ARP33299_P050 | Davies, S. M. K. et al. Pentatricopeptide repeat domain protein 3 associates with the mitochondrial small ribosomal subunit and regulates translation. FEBS Lett. 583, 1853-8 (2009). 19427859 | 19427859 |
819 | MSH2 | OAAF03051 | A rapidly growing human papillomavirus-positive oral tongue squamous cell carcinoma in a 21-year old female: A case report. Oncol Lett. 15, 7702-7706 (2018). 29849799 | 29849799 |
820 | MSN | ARP63015_P050 | Li, J. et al. A strategy to rapidly identify the functional targets of microRNAs by combining bioinformatics and mRNA cytoplasmic/nucleic ratios in culture cells. FEBS Lett. 584, 3198-202 (2010). 20547158 | 20547158 |
821 | MSX1 | ARP31396_T100 | Mizokami, Y. et al. Expression of MSX1 in human normal pituitaries and pituitary adenomas. Endocr. Pathol. 19, 54-61 (2008). 18379900 | 18379900 |
822 | MTf2 | ARP34292_P050 | Loss of PRC2 subunits primes lineage choice during exit of pluripotency. Nat Commun 2021 1 12 6985 34848733 | 34848733 |
823 | Mthfd1 | OAAB01489 | Thangavel, M. et al. Proteomic analysis of rat prefrontal cortex after chronic valproate treatment. J. Neurosci. Res. 92, 927-36 (2014). 24692022 | 24692022 |
824 | MTNR1B | OABF00337 | Melatonin Type 2 Receptor Activation Regulates Blue Light Exposure-Induced Mouse Corneal Epithelial Damage by Modulating Impaired Autophagy and Apoptosis. Int J Mol Sci NULL 23 19 September 2022 | 36232639 |
825 | MTRR | ARP57657_P050 | Richard, E., Desviat, L. R., Ugarte, M. & Pérez, B. Oxidative stress and apoptosis in homocystinuria patients with genetic remethylation defects. J. Cell. Biochem. 114, 183-91 (2013). 22887477 | 22887477 |
826 | MTUS1 | ARP44419_P050 | Negative regulation of EB1 turnover at microtubule plus ends by interaction with microtubule-associated protein ATIP3. Oncotarget. 6, 43557-70 (2015). 26498358 | 26498358 |
827 | MTUS1 | ARP44419_P050 | Reciprocal regulation of Aurora kinase A and ATIP3 in the control of metaphase spindle length. Cell Mol Life Sci 2021 4 78 1765-1779 32789689 | 32789689 |
828 | MUC1 | ARP41446_T100 | Autophagy is decreased in triple-negative breast carcinoma involving likely the MUC1-EGFR-NEU1 signalling pathway. Int J Clin Exp Pathol. 8, 4344-55 (2015). 26191126 | 26191126 |
829 | MUC1 | ARP41446_T100 | GABA selectively increases mucin-1 expression in isolated pig jejunum. Genes Nutr. 10, 47 (2015). 26471792 | 26471792 |
830 | Muc19 | OAEB02736 | Salivary gland organoid culture maintains distinct glandular properties of murine and human major salivary glands. Nat Commun 2022 1 13 3291 35672412 | 35672412 |
831 | MVP | OAGA01032 | Major Vault Protein, a Candidate Gene in 16p11.2 Microdeletion Syndrome, Is Required for the Homeostatic Regulation of Visual Cortical Plasticity. J Neurosci. 38, 3890-3900 (2018). 29540554 | 29540554 |
832 | MX1 | ARP46077_P050 | Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828 | 23103828 |
833 | MYBBP1A | ARP37224_T100 | Zheng, B. et al. Establishment of a proteomic profile associated with gonocyte and spermatogonial stem cell maturation and differentiation in neonatal mice. Proteomics 14, 274-85 (2014). 24339256 | 24339256 |
834 | MYCBP | ARP31860_P050 | Cowell, J. K. & Hawthorn, L. The application of microarray technology to the analysis of the cancer genome. Curr. Mol. Med. 7, 103-20 (2007). 17311536 | 17311536 |
835 | MYCBP | ARP31860_P050 | Ramírez-Valle, F., Braunstein, S., Zavadil, J., Formenti, S. C. & Schneider, R. J. eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy. J. Cell Biol. 181, 293-307 (2008). 18426977 | 18426977 |
836 | MYF5 | OALA07435 | Deficient muscle regeneration potential in sarcopenic COPD patients: Role of satellite cells. J Cell Physiol 2021 4 236 3083-3098 32989805 | 32989805 |
837 | MYH7 | ARP41380_P050 | Tijore, A. et al. Investigating the Spatial Distribution of Integrin beta1 in Patterned Human Mesenchymal Stem Cells Using Super-Resolution Imaging. ACS Appl. Mater. Interfaces 6, 15686-96 (2014). 25153694 | 25153694 |
838 | MYH7 | ARP41380_P050 | Role of Cytoskeletal Tension in the Induction of Cardiomyogenic Differentiation in Micropatterned Human Mesenchymal Stem Cell. Adv Healthc Mater. 4, 1399-407 (2015). 25946615 | 25946615 |
839 | Myh7 | ARP41380_P050 | High glucose induces Drp1-mediated mitochondrial fission via the Orai1 calcium channel to participate in diabetic cardiomyocyte hypertrophy. Cell Death Dis 2021 2 12 216 33637715 | 33637715 |
840 | N/A | OAEA00010 | Bacterial N4-methylcytosine as an epigenetic mark in eukaryotic DNA. Nat Commun 2022 1 13 1072 35228526 | 35228526 |
841 | N/A | OAMA00794 | Comparison of methods for quantitative biomolecular interaction analysis. Anal Bioanal Chem 2022 1 414 661-673 34505164 | 34505164 |
842 | N/A | AMM99021 | Epigenomic features of DNA G-quadruplexes and their roles in regulating rice gene transcription. Plant Physiol 2022 3 188 1632-1648 34893906 | 34893906 |
843 | NAB1 | ARP32032_P050 | Shimoyamada, H. et al. Early growth response-1 induces and enhances vascular endothelial growth factor-A expression in lung cancer cells. Am. J. Pathol. 177, 70-83 (2010). 20489156 | 20489156 |
844 | NAMPT | ARP42255_T100 | Restoration of perivascular adipose tissue function in diet-induced obese mice without changing bodyweight. Br. J. Pharmacol. (2017). 28055105 | 28055105 |
845 | NANOG | OAAB11202 | Identification and characterisation of NANOG+/ OCT-4high/SOX2+ doxorubicin-resistant stem-like cells from transformed trophoblastic cell lines. Oncotarget. 9, 7054-7065 (2018). 29467949 | 29467949 |
846 | NANOG | OAAB11202 | Doxorubicin resistant choriocarcinoma cell line derived spheroidal cells exhibit stem cell markers but reduced invasion. 3 Biotech 184 12 9 September 2022 | 35875180 |
847 | NARS | OAAB07325 | Leucyl-tRNA synthetase is a tumour suppressor in breast cancer and regulates codon-dependent translation dynamics. Nat Cell Biol 307-315 24 3 March 2022 | 35288656 |
848 | NEU1 | ARP44286_T100 | Lipopolysaccharide activates microglia via neuraminidase 1 desialylation of Toll-like Receptor 4. J Neurochem. 155, 403-416 (2020) 32279315 | 32279315 |
849 | NEU1 | ARP44286_T100 | Existence of NEU1 sialidase on mouse thymocytes whose natural substrate is CD5. Glycobiology. 28, 306-317 (2018) 29897583 | 29897583 |
850 | NFIA | ARP32714_P050 | DCC regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation. Elife 2021 NULL 10 NULL 33871356 | 33871356 |
851 | NFKB1 | OAAI00072 | Crucial role of OX40/OX40L signaling in a murine model of asthma. Mol Med Rep. 17, 4213-4220 (2018). 29344664 | 29344664 |
852 | NFKB2 | ARP32718_P050 | Tissue-specific transcription profile of cytokine and chemokine genes associated with flavivirus control and non-lethal neuropathogenesis in rabbits. Virology. 494, 1-14 (2016). 27061052 | 27061052 |
853 | NF-κB2 | ARP32043_P050 | Volger, O. L. et al. Distinctive expression of chemokines and transforming growth factor-beta signaling in human arterial endothelium during atherosclerosis. Am. J. Pathol. 171, 326-37 (2007). 17591977 | 17591977 |
854 | NF-κB2 | ARP32043_P050 | Wang, C.-Y., Yang, P., Li, M. & Gong, F. Characterization of a negative feedback network between SUMO4 expression and NFkappaB transcriptional activity. Biochem. Biophys. Res. Commun. 381, 477-81 (2009). 19222990 | 19222990 |
855 | NIP7 | ARP40833_T100 | Zinzalla, V., Stracka, D., Oppliger, W. & Hall, M. N. Activation of mTORC2 by association with the ribosome. Cell 144, 757-68 (2011). 21376236 | 21376236 |
856 | NKCC2 | ARP41388_P050 | Kelsen, S. et al. Heme oxygenase attenuates angiotensin II-mediated superoxide production in cultured mouse thick ascending loop of Henle cells. Am. J. Physiol. Renal Physiol. 295, F1158-65 (2008). 18701634 | 18701634 |
857 | NKCC2 | ARP41388_P050 | Stec, D. E. et al. Expression of heme oxygenase-1 in thick ascending loop of henle attenuates angiotensin II-dependent hypertension. J. Am. Soc. Nephrol. 23, 834-41 (2012). 22323644 | 22323644 |
858 | NKCC2 | ARP41388_P050 | Polyuria-associated hydronephrosis induced by xenobiotic chemical exposure in mice. Am. J. Physiol. Renal Physiol. 311, F752-F762 (2016). 27440775 | 27440775 |
859 | NLRC4 | AVARP00019_P050 | Inflammasomes are important mediators of cyclophosphamide-induced bladder inflammation. Am J Physiol Renal Physiol. 306, F299-308 (2014). 24285499 | 24285499 |
860 | NLRC4 | AVARP00019_P050 | The potential repertoire of the innate immune system in the bladder: expression of pattern recognition receptors in the rat bladder and a rat urothelial cell line (MYP3 cells). Int Urol Nephrol. 47, 1953-64 (2015). 26490556 | 26490556 |
861 | NLRC4 | AVARP00019_P050 | Immunohistochemical Study of ASC Expression and Distribution in the Hippocampus of an Aged Murine Model of Alzheimer's Disease. Int J Mol Sci 2021 16 22 NULL 34445402 | 34445402 |
862 | NLRP3 | ARP63297_P050 | Tongxinluo May Alleviate Inflammation and Improve the Stability of Atherosclerotic Plaques by Changing the Intestinal Flora. Front Pharmacol 2022 NULL 13 805266 35431939 | 35431939 |
863 | NOTCH4 | ARP32726_P050 | Sun, Y. et al. Trp53 regulates Notch 4 signaling through Mdm2. J. Cell Sci. 124, 1067-76 (2011). 21402876 | 21402876 |
864 | NOTCH4 | ARP32726_P050 | Notch-Induced Expression of FZD7 Requires Noncanonical NOTCH3 Signaling in Human Breast Epithelial Cells. Stem Cells Dev. 25, 522-9 (2016). 26847503 | 26847503 |
865 | NPM1 | ARP34094_T100 | Komorek, J. et al. Adenovirus type 5 E1A and E6 proteins of low-risk cutaneous beta-human papillomaviruses suppress cell transformation through interaction with FOXK1/K2 transcription factors. J. Virol. 84, 2719-31 (2010). 20053746 | 20053746 |
866 | NR1I2 | ARP36016_P050 | Sivertsson, L., Edebert, I., Palmertz, M. P., Ingelman-Sundberg, M. & Neve, E. P. A. Induced CYP3A4 expression in confluent Huh7 hepatoma cells as a result of decreased cell proliferation and subsequent pregnane X receptor activation. Mol. Pharmacol. 83, 659-70 (2013). 23264496 | 23264496 |
867 | NR1I2 | ARP36016_P050 | Dou, W. et al. Chrysin ameliorates chemically induced colitis in the mouse through modulation of a PXR/NF-κB signaling pathway. J. Pharmacol. Exp. Ther. 345, 473-82 (2013). 23536316 | 23536316 |
868 | NR2F2 | P100816_P050 | Déjardin, J. & Kingston, R. E. Purification of proteins associated with specific genomic Loci. Cell 136, 175-86 (2009). 19135898 | 19135898 |
869 | NR4A1 | ARP31941_T100 | Nuclear Receptor Nur77 Facilitates Melanoma Cell Survival under Metabolic Stress by Protecting Fatty Acid Oxidation. Mol Cell. 69, 480-492.e7 (2018). 29395065 | 29395065 |
870 | NR4A1 | ARP45604_P050 | Transformation of the Radial Glia Scaffold Demarcates Two Stages of Human Cerebral Cortex Development. Neuron. 91, 1219-27 (2016). 27657449 | 27657449 |
871 | NR4A2 | ARP38753_P050 | Epigenetic Reprogramming of Cortical Neurons through Alteration of Dopaminergic Circuits. Mol Psychiatry. 19, 1193-1200 (2014). 25023144 | 25023144 |
872 | NRF1 | ARP34523_P050 | Teodoro, J. S. et al. Berberine reverts hepatic mitochondrial dysfunction in high-fat fed rats: a possible role for SirT3 activation. Mitochondrion 13, 637-46 (2013). 24041461 | 24041461 |
873 | NT5C3 | ARP32185_P050 | Preanalytical Stability of Gemcitabine and its Metabolite 2', 2'-Difluoro-2'-Deoxyuridine in Whole Blood-Assessed by Liquid Chromatography Tandem Mass Spectrometry. J Pharm Sci 2015 12 104 4427-4432 26372902 | 26372902 |
874 | NUCB1 | P101699_T100 | Lin, P. et al. Calnuc binds to Alzheimer’s beta-amyloid precursor protein and affects its biogenesis. J. Neurochem. 100, 1505-14 (2007). 17348862 | 17348862 |
875 | NUCB2 | ARP36567_T100 | Suzuki, S. et al. Nucleobindin 2 in human breast carcinoma as a potent prognostic factor. Cancer Sci. 103, 136-43 (2012). 21988594 | 21988594 |
876 | NUCB2 | ARP36567_T100 | Nucleobindin 2 (NUCB2) in human endometrial carcinoma: a potent prognostic factor associated with cell proliferation and migration. Endocr. J. 63, 287-99 (2016). 26842712 | 26842712 |
877 | Nucleophosmin | ARP34094_T100 | Lin, S., Coutinho-Mansfield, G., Wang, D., Pandit, S. & Fu, X.-D. The splicing factor SC35 has an active role in transcriptional elongation. Nat. Struct. Mol. Biol. 15, 819-26 (2008). 18641664 | 18641664 |
878 | NUR77 | ARP31941_T100 | Nur77 suppresses hepatocellular carcinoma via switching glucose metabolism toward gluconeogenesis through attenuating phosphoenolpyruvate carboxykinase sumoylation. Nat Commun. 8, 14420 (2017). 28240261 | 28240261 |
879 | OAS1 | ARP30587_P050 | Li, Q. & Tainsky, M. A. Higher miRNA tolerance in immortal Li-Fraumeni fibroblasts with abrogated interferon signaling pathway. Cancer Res. 71, 255-65 (2011). 21199806 | 21199806 |
880 | OAS1 | ARP51359_P050 | Zhu, W. et al. RIG-I-like receptors mediate innate antiviral response in mouse testis. Mol. Endocrinol. 27, 1455-67 (2013). 23820901 | 23820901 |
881 | OAS1 | ARP51359_P050 | Yu, L. et al. Pattern recognition receptor-initiated innate antiviral response in mouse adipose cells. Immunol. Cell Biol. 92, 105-15 (2014). 24165978 | 24165978 |
882 | OGT | ARP49154_P050-FITC | Robust effect of metabolic syndrome on major metabolic pathways in the myocardium. PLoS One. 14, e0225857 (2019). 31790488 | 31790488 |
883 | ONECUT1 | ARP38481_P050 | Yuan, X.-W. et al. Hepatocyte nuclear factor 6 suppresses the migration and invasive growth of lung cancer cells through p53 and the inhibition of epithelial-mesenchymal transition. J. Biol. Chem. 288, 31206-16 (2013). 24022481 | 24022481 |
884 | OPN1SW | ARP59911_P050 | In vivo analysis of onset and progression of retinal degeneration in the Nr2e3rd7/rd7 mouse model of enhanced S-cone sensitivity syndrome. Sci Rep 2021 1 11 19032 34561487 | 34561487 |
885 | OTC | ARP41766_T100 | Yu, W. et al. Lysine 88 acetylation negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals. J. Biol. Chem. 284, 13669-75 (2009). 19318352 | 19318352 |
886 | OTC | ARP41766_T100 | Walters, M. W. & Wallace, K. B. Urea cycle gene expression is suppressed by PFOA treatment in rats. Toxicol. Lett. 197, 46-50 (2010). 20452409 | 20452409 |
887 | OTC | ARP41766_T100 | Hallows, W. C. et al. Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction. Mol. Cell 41, 139-49 (2011). 21255725 | 21255725 |
888 | OTX2 | ARP32439_P050 | Aluigi, M. G., Angelini, C., Corte, G. & Falugi, C. The sea urchin, Paracentrotus lividus, embryo as a “bioethical” model for neurodevelopmental toxicity testing: effects of diazinon on the intracellular distribution of OTX2-like proteins. Cell Biol. Toxicol. 24, 587-601 (2008). 18224450 | 18224450 |
889 | OTX2 | ARP32439_P050 | Machalińska, A. et al. Endogenous regeneration of damaged retinal pigment epithelium following low dose sodium iodate administration: an insight into the role of glial cells in retinal repair. Exp. Eye Res. 112, 68-78 (2013). 23623997 | 23623997 |
890 | OVOL1 | ARP38500_T100 | OVO-like 1 regulates progenitor cell fate in human trophoblast development. Proc. Natl. Acad. Sci. U.S.A. 112, E6175-84 (2015). 26504231 | 26504231 |
891 | P2X7 | ARP35518_T100 | Extracellular nucleotides as novel, underappreciated pro-metastatic factors that stimulate purinergic signaling in human lung cancer cells. Mol. Cancer. 14, 201 (2015). 26597723 | 26597723 |
892 | P53 | OAAI00285 | Effect of dapagliflozin and/or L-arginine on solid tumor model in mice: The interaction between nitric oxide, transforming growth factor-beta 1, autophagy, and apoptosis. Fundam Clin Pharmacol 968-978 35 6 December 2021 | 33609317 |
893 | PA | OAAF04963 | Proteomics analysis of altered proteins in kidney of mice with aristolochic acid nephropathy using the fluorogenic derivatization-liquid chromatography-tandem mass spectrometry method. Biomed Chromatogr NULL 32 3 March 2018 | 29088495 |
894 | PABPC1 | OAAB01699 | Rbm46 regulates mouse embryonic stem cell differentiation by targeting β-Catenin mRNA for degradation. PLoS One. 12, e0172420 (2017). 28212427 | 28212427 |
895 | PALM | ARP56270_P050 | Konzer, A. et al. Stable isotope labeling in zebrafish allows in vivo monitoring of cardiac morphogenesis. Mol. Cell. Proteomics 12, 1502-12 (2013). 23412571 | 23412571 |
896 | PANX1 | ARP42783_P050 | Dietary Fatty Acids Affect Red Blood Cell Membrane Composition and Red Blood Cell ATP Release in Dairy Cows. Int J Mol Sci. 20, (2019). 31195708 | 31195708 |
897 | Panx2 | ARP42778_T100 | Wang, X.-H., Streeter, M., Liu, Y.-P. & Zhao, H.-B. Identification and characterization of pannexin expression in the mammalian cochlea. J. Comp. Neurol. 512, 336-46 (2009). 19009624 | 19009624 |
898 | Panx2 | ARP42778_T100 | Lai, C. P. K., Bechberger, J. F. & Naus, C. C. Pannexin2 as a novel growth regulator in C6 glioma cells. Oncogene 28, 4402-8 (2009). 19749789 | 19749789 |
899 | Panx2 | ARP42778_T100 | Mylvaganam, S. et al. Hippocampal seizures alter the expression of the pannexin and connexin transcriptome. J. Neurochem. 112, 92-102 (2010). 19840216 | 19840216 |
900 | Panx2 | ARP42778_T100 | Swayne, L. A., Sorbara, C. D. & Bennett, S. A. L. Pannexin 2 is expressed by postnatal hippocampal neural progenitors and modulates neuronal commitment. J. Biol. Chem. 285, 24977-86 (2010). 20529862 | 20529862 |
901 | Panx2 | ARP42778_T100 | Wicki-Stordeur, L. E., Boyce, A. K. J. & Swayne, L. A. Analysis of a pannexin 2-pannexin 1 chimeric protein supports divergent roles for pannexin C-termini in cellular localization. Cell Commun. Adhes. 20, 73-9 (2013). 23659289 | 23659289 |
902 | PANX2 | ARP42778_T100 | Manipulation of Panx1 Activity Increases the Engraftment of Transplanted Lacrimal Gland Epithelial Progenitor Cells. Invest Ophthalmol Vis Sci. 58, 5654-5665 (2017). 29098296 | 29098296 |
903 | PANX2 | ARP42778_T100 | Human stem cells express pannexins. BMC Res Notes. 11, 54 (2018). 29357945 | 29357945 |
904 | PANX2 | ARP42778_T100 | Pannexin 2 is expressed in murine skin and promotes UVB-induced apoptosis of keratinocytes. Mol Biol Cell. mbcE21080387 (2022). 34985913 | 34985913 |
905 | PARL | ARP44851_P050 | Yoshioka, H. et al. The role of PARL and HtrA2 in striatal neuronal injury after transient global cerebral ischemia. J. Cereb. Blood Flow Metab. 33, 1658-65 (2013). 23921894 | 23921894 |
906 | PARL | ARP44851_P050 | Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer's disease. Mol Neurodegener. 16, 15 (2021) 33685483 | 33685483 |
907 | PARP12 | OAAB03451 | DTX3L and ARTD9 inhibit IRF1 expression and mediate in cooperation with ARTD8 survival and proliferation of metastatic prostate cancer cells. Mol Cancer. 13, 125 (2014). 24886089 | 24886089 |
908 | PARP16 | ARP33752_P050 | Di Paola, S., Micaroni, M., Di Tullio, G., Buccione, R. & Di Girolamo, M. PARP16/ARTD15 is a novel endoplasmic-reticulum-associated mono-ADP-ribosyltransferase that interacts with, and modifies karyopherin-s1. PLoS One 7, e37352 (2012). 22701565 | 22701565 |
909 | PARP16 | ARP33751_P050 | SMYD3-PARP16 axis accelerates unfolded protein response and mediates neointima formation. Acta Pharm Sin B 2021 5 11 1261-1273 34094832 | 34094832 |
910 | PAX7 | AAP32742 | Klotho gene silencing promotes pathology in the mdx mouse model of Duchenne muscular dystrophy. Hum. Mol. Genet. 25, 2465-2482 (2016). 27154199 | 27154199 |
911 | PAX7 | ARP32742_P050 | Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration. Development. 138, 3647-56 (2011). 21828093 | 21828093 |
912 | PAX7 | ARP32742_P050 | Cell-autonomous Notch activity maintains the temporal specification potential of skeletal muscle stem cells. Development. 139, 4536-48 (2012). 23136394 | 23136394 |
913 | PAX7 | ARP32742_P050 | Embryonic founders of adult muscle stem cells are primed by the determination gene Mrf4. Dev Biol. 381, 241-55 (2013). 23623977 | 23623977 |
914 | Pax7 | ARP32742_P050 | McDonald, A. A., Kunz, M. D. & McLoon, L. K. Dystrophic changes in extraocular muscles after gamma irradiation in mdx:utrophin(+/-) mice. PLoS One 9, e86424 (2014). 24466085 | 24466085 |
915 | PAX7 | ARP32742_P050 | First Neuromuscular Contact Correlates with Onset of Primary Myogenesis in Rat and Mouse Limb Muscles. PLoS One. 10, e0133811 (2015). 26207754 | 26207754 |
916 | PAX7 | ARP32742_P050 | CD163 interacts with TWEAK to regulate tissue regeneration after ischaemic injury. Nat Commun. 6, 7792 (2015). 26242746 | 26242746 |
917 | PAX7 | ARP32742_P050 | Early myogenic responses to acute exercise before and after resistance training in young men. Physiol Rep. 3, (2015). 26359239 | 26359239 |
918 | PAX7 | ARP32742_P050 | Sparing of the extraocular muscles in mdx mice with absent or reduced utrophin expression: A life span analysis. Neuromuscul. Disord. 25, 873-87 (2015). 26429098 | 26429098 |
919 | PAX7 | ARP32742_P050 | Klotho gene silencing promotes pathology in the mdx mouse model of Duchenne muscular dystrophy. Hum. Mol. Genet. 25, 2465-2482 (2016). 27154199 | 27154199 |
920 | PAX7 | ARP32742_P050 | Cell cycle regulation of embryonic stem cells and mouse embryonic fibroblasts lacking functional Pax7. Cell Cycle. 15, 2931-2942 (2016). 27610933 | 27610933 |
921 | PAX7 | ARP32742_P050 | Laminin differentially regulates the stemness of type I and type II pericytes. Stem Cell Res Ther. 8, 28 (2017). 28173861 | 28173861 |
922 | PAX7 | ARP32742_P050 | A collagen domain-derived short adiponectin peptide activates APPL1 and AMPK signaling pathways and improves glucose and fatty acid metabolisms. J Biol Chem. 293, 13509-13523 (2018). 29991592 | 29991592 |
923 | PAX7 | ARP32742_P050 | The transcription factor Lef1 switches partners from β-catenin to Smad3 during muscle stem cell quiescence. Sci Signal. 11, NULL (2018). 30042129 | 30042129 |
924 | PAX7 | ARP32742_P050 | The role of Pitx2 and Pitx3 in muscle stem cells gives new insights into P38a MAP kinase and redox regulation of muscle regeneration. Elife. 7, (2018). 30106373 | 30106373 |
925 | PAX7 | ARP32742_P050 | PAX3 Confers Functional Heterogeneity in Skeletal Muscle Stem Cell Responses to Environmental Stress. Cell Stem Cell. 24, 958-973.e9 (2019). 31006622 | 31006622 |
926 | PAX7 | ARP32742_P050 | The primary cilium dampens proliferative signaling and represses a G2/M transcriptional network in quiescent myoblasts. BMC Mol Cell Biol. 21, 25 (2020). 32293249 | 32293249 |
927 | PCBP2 | ARP40568_T100 | Han, W. et al. RNA-binding protein PCBP2 modulates glioma growth by regulating FHL3. J. Clin. Invest. 123, 2103-18 (2013). 23585479 | 23585479 |
928 | PCBP2 | ARP40568_T100 | Interplay between PCBP2 and miRNA modulates ARHGDIA expression and function in glioma migration and invasion. Oncotarget. 7, 19483-98 (2016). 26761212 | 26761212 |
929 | PCNA | AVARP03018_T100 | Liu, Z. et al. Human umbilical cord mesenchymal stromal cells rescue mice from acetaminophen-induced acute liver failure. Cytotherapy 16, 1207-19 (2014). 25108650 | 25108650 |
930 | PDE4D | OAGA00330 | Inactivation of oncogenic cAMP-specific phosphodiesterase 4D by miR-139-5p in response to p53 activation. Elife. 5, (2016). 27383270 | 27383270 |
931 | PDE5A | ARP63250_P050 | A phosphodiesterase type-5 inhibitor, sildenafil, induces sperm capacitation and penetration into porcine oocytes in a chemically defined medium. Theriogenology. 85, 428-33 (2016). 26443234 | 26443234 |
932 | PDHA1 | ARP48137_T100 | The tumor suppressor gene lkb1 is essential for glucose homeostasis during zebrafish early development. FEBS Lett 2016 14 590 2076-85 27264935 | 27264935 |
933 | PENK | OAEB00439 | Stress-Related Neuronal Clusters in Sublenticular Extended Amygdala of Basal Forebrain Show Individual Differences of Positions. Front Neural Circuits. 14, 29 (2020). 32547372 | 32547372 |
934 | PERIOSTIN | OAPC00052 | Increased Hemodynamic Load in Early Embryonic Stages Alters Endocardial to Mesenchymal Transition. Front Physiol. 8, 56 (2017). 28228731 | 28228731 |
935 | PEX3 | ARP46090_T100 | Perilipin-2 Deletion Impairs Hepatic Lipid Accumulation by Interfering with Sterol Regulatory Element-binding Protein (SREBP) Activation and Altering the Hepatic Lipidome. J. Biol. Chem. 291, 24231-24246 (2016). 27679530 | 27679530 |
936 | Pfkfb2 | ARP56677_P050 | Lipid Emulsion Containing High Amounts of n3 Fatty Acids (Omegaven) as Opposed to n6 Fatty Acids (Intralipid) Preserves Insulin Signaling and Glucose Uptake in Perfused Rat Hearts. Anesth Analg 2020 1 130 37-48 31274599 | 31274599 |
937 | PFKFB3 | OABF01219 | Glycolysis and oxidative phosphorylation are essential for purinergic receptor-mediated angiogenic responses in vasa vasorum endothelial cells. Am. J. Physiol., Cell Physiol. 312, C56-C70 (2017). 27856430 | 27856430 |
938 | PHACTR1 | ARP55397_P050 | Allain, B. et al. Neuropilin-1 regulates a new VEGF-induced gene, Phactr-1, which controls tubulogenesis and modulates lamellipodial dynamics in human endothelial cells. Cell. Signal. 24, 214-23 (2012). 21939755 | 21939755 |
939 | PHD1 | ARP31419_P050 | Tennant, D. A. & Gottlieb, E. HIF prolyl hydroxylase-3 mediates alpha-ketoglutarate-induced apoptosis and tumor suppression. J. Mol. Med. (Berl). 88, 839-49 (2010). 20383689 | 20383689 |
940 | PHLDA2 | ARP58237_P050 | Dai, H. et al. TSSC3 overexpression associates with growth inhibition, apoptosis induction and enhances chemotherapeutic effects in human osteosarcoma. Carcinogenesis 33, 30-40 (2012). 22021909 | 22021909 |
941 | Pitx2 | ARP35634_T100 | Hatou, S. et al. Functional corneal endothelium derived from corneal stroma stem cells of neural crest origin by retinoic acid and Wnt/beta-catenin signaling. Stem Cells Dev. 22, 828-39 (2013). 22974347 | 22974347 |
942 | PKLR | OAGA00912 | AG-348 enhances pyruvate kinase activity in red blood cells from patients with pyruvate kinase deficiency. Blood. 130, 1347-1356 (2017). 28760888 | 28760888 |
943 | PLCB2 | OAAB05844 | TAS2R16 Activation Suppresses LPS-Induced Cytokine Expression in Human Gingival Fibroblasts. Front Immunol. 12, 726546 (2022). 34975834 | 34975834 |
944 | PMEL | ARP46802_T100 | Indication of Premelanosome Protein (PMEL) Expression Outside of Pigmented Bovine Skin Suggests Functions Beyond Eumelanogenesis. Genes (Basel). 11, NULL (2020). 32668786 | 32668786 |
945 | PMS2 | OAAF04086 | A rapidly growing human papillomavirus-positive oral tongue squamous cell carcinoma in a 21-year old female: A case report. Oncol Lett. 15, 7702-7706 (2018). 29849799 | 29849799 |
946 | PMSG | OPPA01037 | A simple and economic protocol for efficient in vitro fertilization using cryopreserved mouse sperm. PLoS One 2021 10 16 e0259202 34710162 | 34710162 |
947 | PNLIP | ARP33852_T100 | Itoh, M. et al. Partial loss of pancreas endocrine and exocrine cells of human ARX-null mutation: consideration of pancreas differentiation. Differentiation. 80, 118-22 20538404 | 20538404 |
948 | POGZ | ARP39173_P050 | The LEDGF/p75 Integrase Binding Domain Interactome Contributes to the Survival, Clonogenicity, and Tumorsphere Formation of Docetaxel-Resistant Prostate Cancer Cells. Cells 2021 10 10 NULL 34685704 | 34685704 |
949 | POU3F1 | ARP44073_T100 | Immunohistochemical expression profiles of solute carrier transporters in alpha-fetoprotein-producing gastric cancer. Histopathology. 69, 812-821 (2016). 27245475 | 27245475 |
950 | PPAP2A | ARP42721_T100 | Evseenko, D. et al. Lysophosphatidic acid mediates myeloid differentiation within the human bone marrow microenvironment. PLoS One 8, e63718 (2013). 23696850 | 23696850 |
951 | PPARA | ARP34068_P050 | Gu, Q. et al. Genetic ablation of solute carrier family 7a3a leads to hepatic steatosis in zebrafish during fasting. Hepatology. doi:10.1002/hep.27356 (2014). 25130427 | 25130427 |
952 | PPARD | ARP38765_T100 | Pregnancy-associated changes of peroxisome proliferator-activated receptor delta (PPARD) and cytochrome P450 family 21 subfamily A member 2 (CYP21A2) expression in the bovine corpus luteum. J Reprod Dev. 66, 205-213 (2020). 32037375 | 32037375 |
953 | PPARD | ARP38765_T100 | Rapid acceleration of KRAS-mutant pancreatic carcinogenesis via remodeling of tumor immune microenvironment by PPARδ. Nat Commun 2022 1 13 2665 35562376 | 35562376 |
954 | PPP2R2B | OAAB05193 | Combined inhibition of EZH2 and histone deacetylases as a potential epigenetic therapy for non-small-cell lung cancer cells. Cancer Sci. 107, 955-62 (2016). 27116120 | 27116120 |
955 | PRC1 | OAAN02101 | Upfront admixing antibodies and EGFR inhibitors preempts sequential treatments in lung cancer models. EMBO Mol Med. 13, e13144 (2021). 33660397 | 33660397 |
956 | PRDM1 | P100596_P050 | VEGF-Mediated Induction of PRD1-BF1/Blimp1 Expression Sensitizes Tumor Vasculature to Oncolytic Virus Infection. Cancer Cell. 28, 210-24 (2015). 26212250 | 26212250 |
957 | PRDX1 | ARP48454_P050 | Functional genomics study of acute heat stress response in the small yellow follicles of layer-type chickens. Sci Rep. 8, 1320 (2018). 29358656 | 29358656 |
958 | PRDX1 | ARP48454_P050 | A novel NRF2/ARE inhibitor gossypol induces cytotoxicity and sensitizes chemotherapy responses in chemo-refractory cancer cells. J Food Drug Anal 2021 4 29 638-652 35649133 | 35649133 |
959 | PRKRA | ARP40475_P050 | Yoshida, K. et al. Interaction between PKR and PACT mediated by LPS-inducible NF-κB in human gingival cells. J. Cell. Biochem. 113, 165-73 (2012). 21882225 | 21882225 |
960 | PRL | OAAB01514 | Reichenbach, A., Steyn, F. J., Sleeman, M. W. & Andrews, Z. B. Ghrelin receptor expression and colocalization with anterior pituitary hormones using a GHSR-GFP mouse line. Endocrinology 153, 5452-66 (2012). 22962259 | 22962259 |
961 | PRMT2 | ARP40196_T100 | Zhong, J. et al. Identification and expression analysis of a novel transcript of the human PRMT2 gene resulted from alternative polyadenylation in breast cancer. Gene 487, 1-9 (2011). 21820040 | 21820040 |
962 | PRMT2 | ARP40196_T100 | Zhong, J. et al. Identification and characterization of novel spliced variants of PRMT2 in breast carcinoma. FEBS J. 279, 316-35 (2012). 22093364 | 22093364 |
963 | PRMT2 | ARP40196_T100 | Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828 | 23103828 |
964 | PRMT2 | ARP40196_T100 | Burton, A. et al. Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo. Cell Rep. 5, 687-701 (2013). 24183668 | 24183668 |
965 | PRMT2 | ARP40196_T100 | Arginine Methylation by PRMT2 Controls the Functions of the Actin Nucleator Cobl. Dev Cell. 45, 262-275.e8 (2018). 29689199 | 29689199 |
966 | Prp19 | ARP43158_T100 | Song, G., Cui, Y., Zhong, N. & Han, J. Proteomic characterisation of pancreatic islet beta-cells stimulated with pancreatic carcinoma cell conditioned medium. J. Clin. Pathol. 62, 802-7 (2009). 19403515 | 19403515 |
967 | PSAT | ARP46303_P050 | Clinical Implication of Serine Metabolism-Associated Enzymes in Colon Cancer. Oncology. 89, 351-9 (2015). 26439504 | 26439504 |
968 | PSAT1 | ARP46303_P050 | Yang, Y. et al. PSAT1 regulates cyclin D1 degradation and sustains proliferation of non-small cell lung cancer cells. Int. J. Cancer (2014). doi:10.1002/ijc.29150 25142862 | 25142862 |
969 | PSEN1 | ARP58941_P050 | Loss of endophilin-B1 exacerbates Alzheimer's disease pathology. Brain. 138, 2005-19 (2015). 25981964 | 25981964 |
970 | PSMA1 | ARP40417_P050 | Cron, K. R. et al. Proteasome inhibitors block DNA repair and radiosensitize non-small cell lung cancer. PLoS One 8, e73710 (2013). 24040035 | 24040035 |
971 | PSMC5 | ARP38192_T100 | Effects of aging and reproduction on protein quality control in soma and gametes of Drosophila melanogaster. Aging Cell. 11, 634-43 (2012). 22507075 | 22507075 |
972 | PTCH1 | ARP44249_P050 | Antagonizing the Hedgehog Pathway with Vismodegib Impairs Malignant Pleural Mesothelioma Growth In Vivo by Affecting Stroma. Mol. Cancer Ther. 15, 1095-105 (2016). 26839306 | 26839306 |
973 | PTCH1 | ARP44249_P050 | Impaired response of the bronchial epithelium to inflammation characterizes severe equine asthma. BMC Genomics. 18, 708 (2017). 28886691 | 28886691 |
974 | PTGER1 | OABF01677 | The role of prostaglandin and E series prostaglandin receptor type 4 receptors in the development of bladder overactivity in a rat model of chemically induced prostatic inflammation. BJU Int. 124, 883-891 (2019). 31166645 | 31166645 |
975 | Pthlh | ARP33885_T100 | Zhao, C.-M. et al. Gene expression profiling of gastric mucosa in mice lacking CCK and gastrin receptors. Regul. Pept. 192-193C, 35-44 (2014). 25160855 | 25160855 |
976 | PTHLH | ARP33885_T100 | Role of the Parathyroid Hormone Type 1 Receptor (PTH1R) as a Mechanosensor in Osteocyte Survival. J Bone Miner Res. 30, 1231-44 (2015). 25529820 | 25529820 |
977 | PTHrP | ARP33885_T100 | Müller, M., Gagiannis, S., Nawroth, P. P., Brune, M. & Schilling, T. Activation of the receptor for parathyroid hormone and parathyroid hormone related protein induces apoptosis via the extrinsic and intrinsic signaling pathway. Int. J. Mol. Med. 24, 373-80 (2009). 19639230 | 19639230 |
978 | PTOV1 | ARP50614_P050 | Youn, H.-S., Park, U.-H., Kim, E.-J. & Um, S.-J. PTOV1 antagonizes MED25 in RAR transcriptional activation. Biochem. Biophys. Res. Commun. 404, 239-44 (2011). 21110951 | 21110951 |
979 | RAB11A | ARP63742_P050 | Rab22a controls MHC-I intracellular trafficking and antigen cross-presentation by dendritic cells. EMBO Rep. 17, 1753-1765 (2016). 27861124 | 27861124 |
980 | RAB14 | AVARP13107_P050 | Kanzaki, H. et al. Identification of direct targets for the miR-17-92 cluster by proteomic analysis. Proteomics 11, 3531-9 (2011). 21751348 | 21751348 |
981 | RAB14 | AVARP13107_P050 | Farhoud, M. H. et al. Impaired ubiquitin-proteasome-mediated PGC-1a protein turnover and induced mitochondrial biogenesis secondary to complex-I deficiency. Proteomics 12, 1349-62 (2012). 22589185 | 22589185 |
982 | RAB14 | AVARP13107_P050 | Rab14 regulation of claudin-2 trafficking modulates epithelial permeability and lumen morphogenesis. Mol Biol Cell. 25, 1744-54 (2014). 24694596 | 24694596 |
983 | RAB14 | AVARP13107_P050 | Rab11-FIP1A regulates early trafficking into the recycling endosomes. Exp Cell Res. 340, 259-73 (2016). 26790954 | 26790954 |
984 | RAB22A | ARP57434_P050 | Rab22a controls MHC-I intracellular trafficking and antigen cross-presentation by dendritic cells. EMBO Rep. 17, 1753-1765 (2016). 27861124 | 27861124 |
985 | RAB31 | ARP61983_P050 | Defective RAB31-mediated megakaryocytic early endosomal trafficking of VWF, EGFR, and M6PR in RUNX1 deficiency. Blood Adv 2022 NULL NULL NULL 35839075 | 35839075 |
986 | RAB5A | ARP56563_P050 | Large-scale isolation and cytotoxicity of extracellular vesicles derived from activated human natural killer cells. J Extracell Vesicles. 6, 1294368 (2017). 28326171 | 28326171 |
987 | RAD23A | ARP42211_T100 | USF-1 is critical for maintaining genome integrity in response to UV-induced DNA photolesions. PLoS Genet. 8, e1002470 (2012). 22291606 | 22291606 |
988 | RAPGEF3 | ARP52140_P050 | Absence of EPAC1 Signaling to Stabilize CFTR in Intestinal Organoids. Cells NULL 11 15 July 2022 | 35892592 |
989 | RASSF7 | ARP34390_T100 | Lim, S. et al. Carbonyl reductase 1 is an essential regulator of skeletal muscle differentiation and regeneration. Int. J. Biochem. Cell Biol. 45, 1784-93 (2013). 20629633 | 20629633 |
990 | RB1 | OAAB16108 | Mathematical modelling of breast cancer cells in response to endocrine therapy and Cdk4/6 inhibition. J R Soc Interface. 17, 20200339 (2020). 32842890 | 32842890 |
991 | RBM28 | ARP40890_P050 | Nousbeck, J. et al. Alopecia, neurological defects, and endocrinopathy syndrome caused by decreased expression of RBM28, a nucleolar protein associated with ribosome biogenesis. Am. J. Hum. Genet. 82, 1114-21 (2008). 18439547 | 18439547 |
992 | RBM38 | ARP40862_P050 | Therapeutic modulation of RNA-binding protein Rbm38 facilitates re-endothelialization after arterial injury. Cardiovasc Res. 115, 1804-1810 (2019). 30843048 | 30843048 |
993 | RCOR1 | ARP39178_T100 | Packer, A. N., Xing, Y., Harper, S. Q., Jones, L. & Davidson, B. L. The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington’s disease. J. Neurosci. 28, 14341-6 (2008). 19118166 | 19118166 |
994 | RDH12 | ARP52972_P050 | In situ autofluorescence lifetime assay of a photoreceptor stimulus response in mouse retina and human retinal organoids. Biomed Opt Express 2022 6 13 3476-3492 35781966 | 35781966 |
995 | RDh8 | ARP65373_P050 | In situ autofluorescence lifetime assay of a photoreceptor stimulus response in mouse retina and human retinal organoids. Biomed Opt Express 2022 6 13 3476-3492 35781966 | 35781966 |
996 | RETREG1 | ARP44827_T100 | FAM134B induces tumorigenesis and epithelial-to-mesenchymal transition via Akt signaling in hepatocellular carcinoma. Mol Oncol. 13, 792-810 (2019). 30556279 | 30556279 |
997 | RHBDL2 | OACA03576 | Thrombomodulin Functional Domains Support Osteoblast Differentiation and Bone Healing in Diabetes in Mice. J Bone Miner Res 1812-1823 35 9 September 2020 | 32329910 |
998 | RHOT1 | ARP44817_P050 | Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition. J Cell Biol. 218, 1871-1890 (2019). 31068376 | 31068376 |
999 | RHOX8 | ARP36806_P050 | Welborn, J.P. et al. Rhox8 Ablation in the Sertoli Cells Using a Tissue-Specific RNAi Approach Results in Impaired Male Fertility in Mice. Biol Reprod. 2015 Jul; 93(1): 8. 25972016 | 25972016 |
1000 | RHOX8 | ARP36807_P050 | Welborn, J.P. et al. Rhox8 Ablation in the Sertoli Cells Using a Tissue-Specific RNAi Approach Results in Impaired Male Fertility in Mice. Biol Reprod. 2015 Jul; 93(1): 8. 25972016 | 25972016 |
1001 | RHOX8 | ARP37849_P050 | Welborn, J.P. et al. Rhox8 Ablation in the Sertoli Cells Using a Tissue-Specific RNAi Approach Results in Impaired Male Fertility in Mice. Biol Reprod. 2015 Jul; 93(1): 8. 25972016 | 25972016 |
1002 | RIPK3 | ARP31513_T100 | Mesenchymal Stem/Stromal Cells and their Extracellular Vesicle Progeny Decrease Injury in Poststenotic Swine Kidney Through Different Mechanisms. Stem Cells Dev. 29, 1190-1200 (2020) 32657229 | 32657229 |
1003 | RNF8 | ARP40071_T100 | The effects of chemotherapy with bleomycin, etoposide, and cis-platinum (BEP) on rat sperm chromatin remodeling, fecundity and testicular gene expression in the progeny. Biol Reprod. 89, 85 (2013). 23986570 | 23986570 |
1004 | ROBO2 | ARP45396_P050 | Synaptogenic activity of the axon guidance molecule Robo2 underlies hippocampal circuit function. Cell Rep 2021 3 37 109828 34686348 | 34686348 |
1005 | ROR1 | OABF00363 | Smartphone based on-chip fluorescence imaging and capillary flow velocity measurement for detecting ROR1+ cancer cells from buffy coat blood samples on dual-layer paper microfluidic chip. Biosens Bioelectron. 153, 112042 (2020) 32056660 | 32056660 |
1006 | RPL13 | ARP40217_P050 | Hartl, T. A. et al. Regulation of ribosome biogenesis by nucleostemin 3 promotes local and systemic growth in Drosophila. Genetics 194, 101-15 (2013). 23436180 | 23436180 |
1007 | RPL8 | ARP40215_T100 | Wong, C. C., Traynor, D., Basse, N., Kay, R. R. & Warren, A. J. Defective ribosome assembly in Shwachman-Diamond syndrome. Blood 118, 4305-12 (2011). 21803848 | 21803848 |
1008 | RPL8 | ARP40215_T100 | Adenylyl cyclase A mRNA localized at the back of cells is actively translated in live chemotaxing Dictyostelium. J Cell Sci. 131, NULL (2018). 29618632 | 29618632 |
1009 | RPN2 | ARP45400_P050 | Expression of ribophorine II is a promising prognostic factor in human gastric adenocarcinoma. Int. J. Oncol. 50, 448-456 (2017). 28035352 | 28035352 |
1010 | RPS16 | ARP33535_T100 | Okada, K. et al. Expression analysis of MIF4GD in the rat testis. J. Reprod. Dev. 57, 256-61 (2011). 21157122 | 21157122 |
1011 | RPS16 | ARP33535_T100 | Sugihara, Y. et al. Identification and expression of an autosomal paralogue of ribosomal protein S4, X-linked, in mice: potential involvement of testis-specific ribosomal proteins in translation and spermatogenesis. Gene 521, 91-9 (2013). 23500592 | 23500592 |
1012 | RPS28 | ARP65601_P050 | A tRNA-Derived Small RNA Regulates Ribosomal Protein S28 Protein Levels after Translation Initiation in Humans and Mice. Cell Rep. 29, 3816-3824.e4 (2019). 31851915 | 31851915 |
1013 | RPS6KA2 | ARP56170_P050 | Targeting HOTAIRM1 ameliorates glioblastoma by disrupting mitochondrial oxidative phosphorylation and serine metabolism. iScience 104823 25 8 August 2022 | 35992092 |
1014 | RPS6KB1 | OAAF07416 | Mitochondrial complex I inhibitors suppress tumor growth through concomitant acidification of the intra- and extracellular environment. iScience. 24, 103497 (2021). 34934919 | 34934919 |
1015 | RRP1 | ARP45812_P050 | Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828 | 23103828 |
1016 | RTN3 | OABB01421 | Infants Uniquely Express High Levels of RBM3 and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain. Dev Neurosci. 40, 325-336 (2018). 30399610 | 30399610 |
1017 | RUNX2 | OALA04014 | RUNX2 controls human IPO8 basal transcription in Saos-2 cells. Mol Med Rep. 14, 1418-24 (2016). 27277970 | 27277970 |
1018 | RUVBL2 | ARP32379_P050 | Barthéléry, M., Jaishankar, A., Salli, U. & Vrana, K. E. Reptin52 expression during in vitro neural differentiation of human embryonic stem cells. Neurosci. Lett. 452, 47-51 (2009). 19444951 | 19444951 |
1019 | S1PR5 | ARP42661_T100 | Sphingosine 1-phospate differentially modulates maturation and function of human Langerhans-like cells. J. Dermatol. Sci. 82, 9-17 (2016). 26803226 | 26803226 |
1020 | SARDH | ARP42344_T100 | Khan, A. P. et al. The role of sarcosine metabolism in prostate cancer progression. Neoplasia 15, 491-501 (2013). 23633921 | 23633921 |
1021 | SART3 | ARP39128_T100 | Cellular Immune Responses for Squamous Cell Carcinoma Antigen Recognized by T Cells 3 in Patients with Hepatocellular Carcinoma. PLoS ONE. 12, e0170291 (2017). 28114424 | 28114424 |
1022 | SBDS | ARP45719_T100 | Sezgin, G. et al. Impaired growth, hematopoietic colony formation, and ribosome maturation in human cells depleted of Shwachman-Diamond syndrome protein SBDS. Pediatr. Blood Cancer 60, 281-6 (2013). 22997148 | 22997148 |
1023 | SCARB1 | ARP63158_P050 | Fu, Y. et al. ABCA12 Regulates ABCA1-Dependent Cholesterol Efflux from Macrophages and the Development of Atherosclerosis. Cell Metab. 18, 225-38 (2013). 23931754 | 23931754 |
1024 | SCN5 | ARP34934_P050 | Matsushita, N. et al. Nicorandil improves electrical remodelling, leading to the prevention of electrically induced ventricular tachyarrhythmia in a mouse model of desmin-related cardiomyopathy. Clin. Exp. Pharmacol. Physiol. 41, 89-97 (2014). 24117876 | 24117876 |
1025 | SCXA | OAAB00449 | The effects of scaffold architecture and fibrin gel addition on tendon cell phenotype. J Mater Sci Mater Med. 26, 5349 (2015) 25578703 | 25578703 |
1026 | SERPINA1 | OABB01837 | Human Urinary Epithelial Cells as a Source of Engraftable Hepatocyte-Like Cells Using Stem Cell Technology. Cell Transplant. 25, 2221-2243 (2016). 27512979 | 27512979 |
1027 | SERPINB5 | ARP42055_T100 | Mardin, W. A. et al. SERPINB5 and AKAP12 - expression and promoter methylation of metastasis suppressor genes in pancreatic ductal adenocarcinoma. BMC Cancer 10, 549 (2010). 20939879 | 20939879 |
1028 | SERPINB5 | ARP42055_T100 | Hrabakova, R. et al. Cancer cell resistance to aurora kinase inhibitors: identification of novel targets for cancer therapy. J. Proteome Res. 12, 455-69 (2013). 23151231 | 23151231 |
1029 | SERPINB5 | ARP42055_T100 | SERPINB5 Promoter Hypomethylation Differentiates Pancreatic Ductal Adenocarcinoma From Pancreatitis. Pancreas. 45, 743-7 (2016). 26646275 | 26646275 |
1030 | SERPINH1 | OACA06643 | Baseline Clinical and Biomarker Characteristics of Biobank Innovations for Chronic Cerebrovascular Disease With Alzheimer's Disease Study: BICWALZS. Psychiatry Investig. (2022). 35042283 | 35042283 |
1031 | SERTAD1 | ARP34309_T100 | Sertad1 Induces Neurological Injury after Ischemic Stroke via the CDK4/p-Rb Pathway. Mol Cells. (2022). 35014620 | 35014620 |
1032 | SetD2 | ARP47617_T100 | Barrand, S., Andersen, I. S. & Collas, P. Promoter-exon relationship of H3 lysine 9, 27, 36 and 79 methylation on pluripotency-associated genes. Biochem. Biophys. Res. Commun. 401, 611-7 (2010). 20920475 | 20920475 |
1033 | SETD2 | ARP47617_T100 | Identification of functional cooperative mutations of SETD2 in human acute leukemia. Nat Genet. 46, 287-93 (2014). 24509477 | 24509477 |
1034 | SF1 | ARP41214_T100 | Formation of nuclear bodies by the lncRNA Gomafu-associating proteins Celf3 and SF1. Genes Cells. 19, 704-21 (2014). 25145264 | 25145264 |
1035 | SFRS1 | ARP40691_P050 | Li, J. et al. A strategy to rapidly identify the functional targets of microRNAs by combining bioinformatics and mRNA cytoplasmic/nucleic ratios in culture cells. FEBS Lett. 584, 3198-202 (2010). 20547158 | 20547158 |
1036 | SFRS10 | ARP40528_T100 | Fu, K. et al. Tra2beta protein is required for tissue-specific splicing of a smooth muscle myosin phosphatase targeting subunit alternative exon. J. Biol. Chem. 287, 16575-85 (2012). 22437831 | 22437831 |
1037 | SGPP2 | ARP45734_T100 | Rajkumar Vutukuri, et al. Alteration of sphingolipid metabolism as a putative mechanism underlying LPS-induced BBB disruption. 172-185 (2018). 29023711 | 29023711 |
1038 | SHH | ARP44235_P050 | Stage-Specific Effect of Inositol Hexaphosphate on Cancer Stem Cell Pool during Growth and Progression of Prostate Tumorigenesis in TRAMP Model. Cancers (Basel) NULL 14 17 August 2022 | 36077751 |
1039 | SIGLEC1 | OASA04956 | Mouse Siglec-1 Mediates trans-Infection of Surface-bound Murine Leukemia Virus in a Sialic Acid N-Acyl Side Chain-dependent Manner. J Biol Chem. 290, 27345-59 (2015). 26370074 | 26370074 |
1040 | SIM1 | ARP33296_P050 | Functional dissection of the Pax6 paired domain: Roles in neural tube patterning and peripheral nervous system development. Dev Biol. 413, 86-103 (2016) 26187199 | 26187199 |
1041 | SIP1 | ARP39141_P050 | Regulation of trunk neural crest delamination by dEF1 and Sip1 in the chicken embryo. Dev. Growth Differ. 58, 205-14 (2016). 26691438 | 26691438 |
1042 | SIRT3 | ARP32389_P050 | Lanza, I. R. et al. Endurance exercise as a countermeasure for aging. Diabetes 57, 2933-42 (2008). 18716044 | 18716044 |
1043 | SIRT3 | ARP32389_P050 | Dong, R. et al. Cells with dendritic cell morphology and immunophenotype, binuclear morphology, and immunosuppressive function in dendritic cell cultures. Cell. Immunol. 272, 1-10 (2011). 22087287 | 22087287 |
1044 | SIRT3 | ARP32389_P050 | Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas. Sci Adv. 2, e1601132 (2016). 27847869 | 27847869 |
1045 | SIX1 | ARP32375_P050 | Lee, S. H. et al. Transcription coactivator Eya2 is a critical regulator of physiological hypertrophy. J. Mol. Cell. Cardiol. 52, 718-26 (2012). 22197309 | 22197309 |
1046 | SLC10A2 | OAEB00210 | Bile acids are important direct and indirect regulators of the secretion of appetite- and metabolism-regulating hormones from the gut and pancreas. Mol Metab. 11, 84-95 (2018). 29656109 | 29656109 |
1047 | SLC12A1 | OABB01331 | "Reversed polarization" of Na/K-ATPase-a sign of inverted transport in the human endolymphatic sac: a super-resolution structured illumination microscopy (SR-SIM) study. Cell Tissue Res. 379, 445-457 (2020). 31713726 | 31713726 |
1048 | SLC12A2 | OABB01332 | Impaired glucose tolerance, glucagon, and insulin responses in mice lacking the loop diuretic-sensitive Nkcc2a transporter. Am J Physiol Cell Physiol. 317, C843-C856 (2019). 31365295 | 31365295 |
1049 | SLC12A5 | OASE00240 | Pharmaco-resistant Neonatal Seizures: Critical Mechanistic Insights from a Chemoconvulsant Model. Dev Neurobiol. 78, 1117-1130 (2018). 30136373 | 30136373 |
1050 | SLC12A5 | OASE00240 | TrkB agonists prevent postischemic emergence of refractory neonatal seizures in mice. JCI Insight. 5, NULL (2020). 32427585 | 32427585 |
1051 | SLC19A1 | ARP44167_T100 | Marchi, E. et al. Pralatrexate is synergistic with the proteasome inhibitor bortezomib in in vitro and in vivo models of T-cell lymphoid malignancies. Clin. Cancer Res. 16, 3648-58 (2010). 20501616 | 20501616 |
1052 | SLC19A1 | ARP44167_T100 | Halwachs, S., Lakoma, C., Schäfer, I., Seibel, P. & Honscha, W. The antiepileptic drugs phenobarbital and carbamazepine reduce transport of methotrexate in rat choroid plexus by down-regulation of the reduced folate carrier. Mol. Pharmacol. 80, 621-9 (2011). 21737571 | 21737571 |
1053 | SLC1A4 | OAAN01042 | Poly(I:C) alters placental and fetal brain amino acid transport in a rat model of maternal immune activation. Am J Reprod Immunol e13115 81 6 June 2019 | 30924965 |
1054 | SLC1A5 | ARP42247_T100 | Zhu, Y. et al. L-Glutamine deprivation induces autophagy and alters the mTOR and MAPK signaling pathways in porcine intestinal epithelial cells. Amino Acids (2014). doi:10.1007/s00726-014-1785-0 24997162 | 24997162 |
1055 | SLC1A5 | ARP42247_T100 | Metabolic maintenance of cell asymmetry following division in activated T lymphocytes. Nature. 532, 389-93 (2016). 27064903 | 27064903 |
1056 | SLC1A5 | ARP42247_T100 | Protein Restriction with Amino Acid-Balanced Diets Shrinks Circulating Pool Size of Amino Acid by Decreasing Expression of Specific Transporters in the Small Intestine. PLoS ONE. 11, e0162475 (2016). 27611307 | 27611307 |
1057 | SLC22A1 | ARP41516_T100 | Expression of choline and acetylcholine transporters in synovial tissue and cartilage of patients with rheumatoid arthritis and osteoarthritis. Cell Tissue Res. 359, 465-477 (2015). 25418136 | 25418136 |
1058 | SLC22A1 | ARP41640_T100 | Salomon, J. J. et al. The Cell Line NCl-H441 Is a Useful in Vitro Model for Transport Studies of Human Distal Lung Epithelial Barrier. Mol. Pharm. (2014). doi:10.1021/mp4006536 24524365 | 24524365 |
1059 | SLC22A16 | ARP33061_T100 | Hashimoto, Y. et al. Expression of organic anion-transporting polypeptide 1A2 and organic cation transporter 6 as a predictor of pathologic response to neoadjuvant chemotherapy in triple negative breast cancer. Breast Cancer Res. Treat. 145, 101-11 (2014). 24671357 | 24671357 |
1060 | SLC22A17 | OAEB00639 | Expression of uterine lipocalin 2 and its receptor during early- to mid-pregnancy period in mares. J. Reprod. Dev. (2016). 27980236 | 27980236 |
1061 | SLC23A1 | OAAB09000 | Limited Association Between Ascorbate Concentrations and Vitamin C Transporters in Renal Cell Carcinoma Cells and Clinical Samples. Cell Physiol Biochem. 55, 553-568 (2021). 34599650 | 34599650 |
1062 | SLC26A4 | ARP41739_P050 | Urinary Extracellular Vesicles for Renal Tubular Transporters Expression in Patients With Gitelman Syndrome. Front Med (Lausanne). 8, 679171 (2021) 34179047 | 34179047 |
1063 | SLC27A6 | ARP43781_P050 | Gaccioli, F. et al. Maternal overweight induced by a diet with high content of saturated fat activates placental mTOR and eIF2 alpha signaling and increases fetal growth in rats. Biol. Reprod. 89, 96 (2013). 24006279 | 24006279 |
1064 | SLC29A2 | ARP43822_T100 | Okuda, H., Higashi, Y., Nishida, K., Fujimoto, S. & Nagasawa, K. Contribution of P2X7 receptors to adenosine uptake by cultured mouse astrocytes. Glia 58, 1757-65 (2010). 20645413 | 20645413 |
1065 | SLC34A3 | ARP32173_P050 | Impact of Pals1 on Expression and Localization of Transporters Belonging to the Solute Carrier Family. Front Mol Biosci 2022 NULL 9 792829 35252349 | 35252349 |
1066 | SLC38A2 | ARP33059_P050 | Intermittent Bolus Compared With Continuous Feeding Enhances Insulin and Amino Acid Signaling to Translation Initiation in Skeletal Muscle of Neonatal Pigs. J Nutr 2021 9 151 2636-2645 34159368 | 34159368 |
1067 | SLC39A6 | ARP43931_T100 | Trokovic, N. et al. Exosomal secretion of death bullets: a new way of apoptotic escape? Am. J. Physiol. Endocrinol. Metab. 303, E1015-24 (2012). 22912365 | 22912365 |
1068 | SLC3A2 | OASA02585 | Quantitative Algorithm-Based Paired Imaging Measurement for Antibody-Triggered Endocytosis in Cultured Cells. SLAS Discov. 23, 832-841 (2018). 29505735 | 29505735 |
1069 | SLC3A2 | OAAB00158 | Decrease of Intracellular Glutamine by STF-62247 Results in the Accumulation of Lipid Droplets in von Hippel-Lindau Deficient Cells. Front Oncol 2022 NULL 12 841054 35223522 | 35223522 |
1070 | SLC44A2 | ARP44009_P050 | The choline transporter Slc44a2 controls platelet activation and thrombosis by regulating mitochondrial function. Nat Commun. 11, 3479 (2020). 32661250 | 32661250 |
1071 | SLC47A2 | ARP51904_P050 | Localization of Xenobiotic Transporters Expressed at the Human Blood-Testis Barrier. Drug Metab Dispos 2022 6 50 770-780 35307651 | 35307651 |
1072 | SLC5A8 | OABF01657 | Impaired butyrate absorption in the proximal colon, low serum butyrate and diminished central effects of butyrate on blood pressure in spontaneously hypertensive rats. Acta Physiol (Oxf). 226, e13256 (2019). 30656835 | 30656835 |
1073 | Slc6a9 | ARP42330_P050 | Poly(I:C) alters placental and fetal brain amino acid transport in a rat model of maternal immune activation. Am J Reprod Immunol e13115 81 6 June 2019 | 30924965 |
1074 | Slc7a3 | ARP43806_P050 | FXR1 regulation of parvalbumin interneurons in the prefrontal cortex is critical for schizophrenia-like behaviors. Mol Psychiatry 2021 11 26 6845-6867 33863995 | 33863995 |
1075 | SLPI | OAPB00538 | MyD88 deficiency alters expression of antimicrobial factors in mouse salivary glands. PLoS One. 9, e113333 (2014). 25415419 | 25415419 |
1076 | SMAD3 | OAAB06596 | Uchiyama, Y. et al. SMAD3 functions as a transcriptional repressor of acid-sensing ion channel 3 (ASIC3) in nucleus pulposus cells of the intervertebral disc. J. Bone Miner. Res. 23, 1619-28 (2008). 18466073 | 18466073 |
1077 | SMPDL3B | ARP33875_P050 | Sphingomyelin phosphodiesterase acid-like 3A (SMPDL3A) is a novel nucleotide phosphodiesterase regulated by cholesterol in human macrophages. J Biol Chem. 289, 32895-913 (2014). 25288789 | 25288789 |
1078 | SNAI1 | ARP33314_P050 | Wang, H. et al. PRL-3 down-regulates PTEN expression and signals through PI3K to promote epithelial-mesenchymal transition. Cancer Res. 67, 2922-6 (2007). 17409395 | 17409395 |
1079 | SNAI1 | ARP33314_P050 | Surati, M. et al. Proteomic characterization of non-small cell lung cancer in a comprehensive translational thoracic oncology database. J. Clin. Bioinforma. 1, 1-11 (2011). 21603121 | 21603121 |
1080 | SNAI1 | ARP33314_P050 | Cooper, C. D. O. et al. Identification and characterization of peripheral T-cell lymphoma-associated SEREX antigens. PLoS One 6, e23916 (2011). 21914172 | 21914172 |
1081 | SNRP70 | ARP40275_P050 | Wang, E. & Cambi, F. Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs. J. Biol. Chem. 284, 11194-204 (2009). 19244236 | 19244236 |
1082 | SNRP70 | ARP40439_P050 | Franklin, S. et al. Specialized compartments of cardiac nuclei exhibit distinct proteomic anatomy. Mol. Cell. Proteomics 10, M110.000703 (2011). 20807835 | 20807835 |
1083 | SNRP70 | ARP40439_P050 | Serini, S. et al. DHA induces apoptosis and differentiation in human melanoma cells in vitro: involvement of HuR-mediated COX-2 mRNA stabilization and beta-catenin nuclear translocation. Carcinogenesis 33, 164-73 (2012). 22045024 | 22045024 |
1084 | SNRP70 | ARP40439_P050 | Franklin, S. et al. Quantitative analysis of the chromatin proteome in disease reveals remodeling principles and identifies high mobility group protein B2 as a regulator of hypertrophic growth. Mol. Cell. Proteomics 11, M111.014258 (2012). 22270000 | 22270000 |
1085 | SNRPA | ARP40531_P050 | Wang, E. & Cambi, F. Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs. J. Biol. Chem. 284, 11194-204 (2009). 19244236 | 19244236 |
1086 | SOCS2 | ARP63434_P050 | The Role of GLP1 in Rat Steatotic and Non-Steatotic Liver Transplantation from Cardiocirculatory Death Donors. Cells 2019 12 8 NULL 31835410 | 31835410 |
1087 | SOD1 | OASE00355 | PYP1-4 peptide from Pyropia yezoensis protects against acetaminophen-induced hepatotoxicity in HepG2 cells. Exp Ther Med. 19, 849-860 (2020). 32010245 | 32010245 |
1088 | SOD2 | OASE00357 | Identification and antioxidant activity of synthetic peptides from phycobiliproteins of Pyropia yezoensis. Int J Mol Med. 42, 789-798 (2018). 29717771 | 29717771 |
1089 | SOD2 | OASE00357 | PYP1-4 peptide from Pyropia yezoensis protects against acetaminophen-induced hepatotoxicity in HepG2 cells. Exp Ther Med. 19, 849-860 (2020). 32010245 | 32010245 |
1090 | SOX10 | ARP33326_P050 | Chromatin landscape defined by repressive histone methylation during oligodendrocyte differentiation. J Neurosci. 35, 352-65 (2015). 25568127 | 25568127 |
1091 | SOX10 | ARP33326_P050 | SPECC1L deficiency results in increased adherens junction stability and reduced cranial neural crest cell delamination. Sci Rep. 6, 17735 (2016). 26787558 | 26787558 |
1092 | SOX10 | ARP33326_P050 | Anti-epileptic drug topiramate upregulates TGFβ1 and SOX9 expression in primary embryonic palatal mesenchyme cells: Implications for teratogenicity. PLoS One 2021 2 16 e0246989 33577554 | 33577554 |
1093 | SOX17 | ARP39552_P050 | Kallas, A., Pook, M., Trei, A. & Maimets, T. SOX2 Is Regulated Differently from NANOG and OCT4 in Human Embryonic Stem Cells during Early Differentiation Initiated with Sodium Butyrate. Stem Cells Int. 2014, 298163 (2014). 24707296 | 24707296 |
1094 | SOX17 | ARP39552_P050 | Single-cell transcriptomic profiling of lung endothelial cells identifies dynamic inflammatory and regenerative subpopulations. JCI Insight 2022 11 7 NULL 35511435 | 35511435 |
1095 | SOX18 | ARP33056_P050 | Duong, T. et al. Genetic ablation of SOX18 function suppresses tumor lymphangiogenesis and metastasis of melanoma in mice. Cancer Res. 72, 3105-14 (2012). 22523034 | 22523034 |
1096 | SOX18 | ARP33056_P050 | Deng, Y., Atri, D., Eichmann, A. & Simons, M. Endothelial ERK signaling controls lymphatic fate specification. J. Clin. Invest. 123, 1202-15 (2013). 23391722 | 23391722 |
1097 | Sox18 | ARP33056_P050 | Park, D.-Y. et al. Lymphatic regulator PROX1 determines Schlemm canal integrity and identity. J. Clin. Invest. 124, 3960-3974 (2014). 25061877 | 25061877 |
1098 | SOX2 | ARP31737_P050 | Perry, K. J., Thomas, A. G. & Henry, J. J. Expression of pluripotency factors in larval epithelia of the frog Xenopus: evidence for the presence of cornea epithelial stem cells. Dev. Biol. 374, 281-94 (2013). 23274420 | 23274420 |
1099 | SOX4 | ARP38234_P050 | STAT3-mediated upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer metastasis by regulating SOX4. Mol Cancer. 16, 136 (2017). 28810927 | 28810927 |
1100 | SOX5 | ARP33323_P050 | A Novel Method to Induce Cartilage Regeneration with Cubic Microcartilage. Cells Tissues Organs 251-260 204 44687 October 2017 | 28972948 |
1101 | Sox9 | OAAF00840 | Ferrand, N. et al. Loss of WISP2/CCN5 in estrogen-dependent MCF7 human breast cancer cells promotes a stem-like cell phenotype. PLoS One 9, e87878 (2014). 24498388 | 24498388 |
1102 | SOX9 | OAAF00840 | Kallas, A., Pook, M., Trei, A. & Maimets, T. SOX2 Is Regulated Differently from NANOG and OCT4 in Human Embryonic Stem Cells during Early Differentiation Initiated with Sodium Butyrate. Stem Cells Int. 2014, 298163 (2014). 24707296 | 24707296 |
1103 | SPAG9 | OAAB04262 | Aberrant expression of JNK-associated leucine-zipper protein, JLP, promotes accelerated growth of ovarian cancer. Oncotarget. 7, 72845-72859 (2016). 27655714 | 27655714 |
1104 | SPARC | ARP63168_P050 | SPARC overexpression combined with radiation retards angiogenesis by suppressing VEGF-A via miR‑410 in human neuroblastoma cells. Int. J. Oncol. 49, 1394-406 (2016). 27498840 | 27498840 |
1105 | SPPL2b | ARP44989_P050 | Del Campo, M. et al. BRI2-BRICHOS is increased in human amyloid plaques in early stages of Alzheimer’s disease. Neurobiol. Aging 35, 1596-604 (2014). 24524963 | 24524963 |
1106 | SRF | OAAF00701 | Myc requires RhoA/SRF to reprogram glutamine metabolism. Small GTPases. 1-9 (2016). 27532209 | 27532209 |
1107 | SRP19 | ARP40456_T100 | Arana-Argáez, V. E. et al. Inhibitors of MAPK pathway ERK1/2 or p38 prevent the IL-1{beta}-induced up-regulation of SRP72 autoantigen in Jurkat cells. J. Biol. Chem. 285, 32824-33 (2010). 20729213 | 20729213 |
1108 | STAT1 | ARP38933_P050 | Bone marrow mesenchymal stromal cells with CD47 high expression via the signal transducer and activators of transcription signaling pathway preventing myocardial fibrosis. Int J Clin Exp Pathol. 8, 10555-64 (2015). 26617765 | 26617765 |
1109 | STAT3 | ARP38253_P050 | Deng, W. et al. Bone marrow mesenchymal stromal cells with support of bispecific antibody and ultrasound-mediated microbubbles prevent myocardial fibrosis via the signal transducer and activators of transcription signaling pathway. Cytotherapy 13, 431-40 (2011). 21174489 | 21174489 |
1110 | STAT3 | ARP38253_P050 | Vega, V. L. et al. Activation of the stress response in macrophages alters the M1/M2 balance by enhancing bacterial killing and IL-10 expression. J. Mol. Med. (Berl). doi:10.1007/s00109-014-1201-y (2014). 25163764 | 25163764 |
1111 | STAT3 | ARP38253_P050 | Bone marrow mesenchymal stromal cells with CD47 high expression via the signal transducer and activators of transcription signaling pathway preventing myocardial fibrosis. Int J Clin Exp Pathol. 8, 10555-64 (2015). 26617765 | 26617765 |
1112 | STAT3 | AVARP09057_P050 | Tissue-specific transcription profile of cytokine and chemokine genes associated with flavivirus control and non-lethal neuropathogenesis in rabbits. Virology. 494, 1-14 (2016). 27061052 | 27061052 |
1113 | SULT1A1 | ARP49134_P050 | Yalcin, E. B. et al. Downregulation of sulfotransferase expression and activity in diseased human livers. Drug Metab. Dispos. 41, 1642-50 (2013). 23775849 | 23775849 |
1114 | SUV39H1 | ARP32470_T100 | Enhanced levels of microRNA-125b in vascular smooth muscle cells of diabetic db/db mice lead to increased inflammatory gene expression by targeting the histone methyltransferase Suv39h1. Diabetes. 59, 2904-15 (2010). 20699419 | 20699419 |
1115 | SUV420H1 | ARP34567_P050 | Gatta, R. & Mantovani, R. NF-Y substitutes H2A-H2B on active cell-cycle promoters: recruitment of CoREST-KDM1 and fine-tuning of H3 methylations. Nucleic Acids Res. 36, 6592-607 (2008). 18940868 | 18940868 |
1116 | SUV420H1 | ARP34567_P050 | Murata, T. et al. Epigenetic histone modification of Epstein-Barr virus BZLF1 promoter during latency and reactivation in Raji cells. J. Virol. 86, 4752-61 (2012). 22357272 | 22357272 |
1117 | SVCT1 | OAAB09000 | Pharmacokinetic and anti-cancer properties of high dose ascorbate in solid tumours of ascorbate-dependent mice. Free Radic. Biol. Med. 99, 451-462 (2016). 27567539 | 27567539 |
1118 | SYNGR4 | OAPB01027 | Motor neuron translatome reveals deregulation of SYNGR4 and PLEKHB1 in mutant TDP-43 amyotrophic lateral sclerosis models. Hum Mol Genet. 29, 2647-2661 (2020). 32686835 | 32686835 |
1119 | SYP | ARP45435_P050 | Stenkamp-Strahm, C. M., Kappmeyer, A. J., Schmalz, J. T., Gericke, M. & Balemba, O. High-fat diet ingestion correlates with neuropathy in the duodenum myenteric plexus of obese mice with symptoms of type 2 diabetes. Cell Tissue Res. 354, 381-94 (2013). 23881404 | 23881404 |
1120 | SYP | ARP45435_P050 | TRPM7 is critical for short-term synaptic depression by regulating synaptic vesicle endocytosis. Elife. 10, NULL (2021) 34569930 | 34569930 |
1121 | SYT13 | OAAB02896 | Amido-Bridged Nucleic Acid-Modified Antisense Oligonucleotides Targeting SYT13 to Treat Peritoneal Metastasis of Gastric Cancer. Mol Ther Nucleic Acids. 22, 791-802 (2020). 33230476 | 33230476 |
1122 | SYT13 | OAAB02896 | Synaptotagmin 13 Is Highly Expressed in Estrogen Receptor-Positive Breast Cancer. Curr Oncol. 28, 4080-4092 (2021). 34677264 | 34677264 |
1123 | SYT7 | OASE00272 | CREB Promotes Beta Cell Gene Expression by Targeting Its Coactivators to Tissue-Specific Enhancers. Mol Cell Biol. 39, (2019). 31182641 | 31182641 |
1124 | TAF15 | ARP30112_P050 | Ko, S. Y., Lengyel, E. & Naora, H. The Müllerian HOXA10 gene promotes growth of ovarian surface epithelial cells by stimulating epithelial-stromal interactions. Mol. Cell. Endocrinol. 317, 112-9 (2010). 20048082 | 20048082 |
1125 | TARDBP | ARP35837_P050 | LIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance. Mol Cell. 48, 195-206 (2012). 22959275 | 22959275 |
1126 | TARDBP | ARP35838_P050 | Low molecular weight species of TDP-43 generated by abnormal splicing form inclusions in amyotrophic lateral sclerosis and result in motor neuron death. Acta Neuropathol. 130, 49-61 (2015). 25788357 | 25788357 |
1127 | TARDBP | ARP38941_T100 | Estes, P. S. et al. Wild-type and A315T mutant TDP-43 exert differential neurotoxicity in a Drosophila model of ALS. Hum. Mol. Genet. 20, 2308-21 (2011). 21441568 | 21441568 |
1128 | TARDBP | ARP38942_T100 | Stress Granule Assembly Can Facilitate but Is Not Required for TDP-43 Cytoplasmic Aggregation. Biomolecules. 10, (2020). 32992901 | 32992901 |
1129 | TARDBP | ARP38941_T100 | Frontotemporal Lobar Degeneration Case with an N-Terminal TUBA4A Mutation Exhibits Reduced TUBA4A Levels in the Brain and TDP-43 Pathology. Biomolecules 2022 3 12 NULL 35327632 | 35327632 |
1130 | TAZ | OAAB05400 | Ciavarella, S., Dammacco, F., De Matteo, M., Loverro, G. & Silvestris, F. Umbilical cord mesenchymal stem cells: role of regulatory genes in their differentiation to osteoblasts. Stem Cells Dev. 18, 1211-20 (2009). 19125623 | 19125623 |
1131 | TBX15 | ARP47723_T100 | Global analysis of DNA methylation in hepatocellular carcinoma by a liquid hybridization capture-based bisulfite sequencing approach. Clin Epigenetics. 7, 86 (2015). 26300991 | 26300991 |
1132 | TBX5 | ARP33403_P050 | Lu, J. et al. Induction of apoptosis and inhibition of cell growth by tbx5 knockdown contribute to dysmorphogenesis in Zebrafish embryos. J. Biomed. Sci. 18, 73 (2011). 21982178 | 21982178 |
1133 | TBX5 | ARP33403_P050 | Zhang, Y., Huang, L., Zuo, Z., Chen, Y. & Wang, C. Phenanthrene exposure causes cardiac arrhythmia in embryonic zebrafish via perturbing calcium handling. Aquat. Toxicol. 142-143, 26-32 (2013). 23948075 | 23948075 |
1134 | TBX5 | ARP33403_P050 | Baban, A. et al. Holt-Oram syndrome with intermediate atrioventricular canal defect, and aortic coarctation: functional characterization of a de novo TBX5 mutation. Am. J. Med. Genet. A 164A, 1419-24 (2014). 24664498 | 24664498 |
1135 | TBX5 | ARP33403_P050 | The Cardiac TBX5 Interactome Reveals a Chromatin Remodeling Network Essential for Cardiac Septation. Dev Cell. 36, 262-75 (2016). 26859351 | 26859351 |
1136 | TBX6 | ARP33405_P050 | Leschik, J., Stefanovic, S., Brinon, B. & Pucéat, M. Cardiac commitment of primate embryonic stem cells. Nat. Protoc. 3, 1381-7 (2008). 18772864 | 18772864 |
1137 | TBX6 | ARP33405_P050 | Chen, Y.-L. et al. Smad6 inhibits the transcriptional activity of Tbx6 by mediating its degradation. J. Biol. Chem. 284, 23481-90 (2009). 19561075 | 19561075 |
1138 | TBX6 | ARP33405_T100 | Cardiac commitment of primate embryonic stem cells. Nat Protoc 1381-7 3 9 September 2008 | 18772864 |
1139 | TDP2 | ARP33010_P050 | Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan. Nucleic Acids Res. 45, 1159-1176 (2017). 28180300 | 28180300 |
1140 | TDP43 | ARP38942_T100 | Bannister, J. P. et al. Ca(V)1.2 channel N-terminal splice variants modulate functional surface expression in resistance size artery smooth muscle cells. J. Biol. Chem. 286, 15058-66 (2011). 21358643 | 21358643 |
1141 | TEAD1 | ARP39521_P050 | Ribas, R. et al. Members of the TEAD family of transcription factors regulate the expression of Myf5 in ventral somitic compartments. Dev. Biol. 355, 372-80 (2011). 21527258 | 21527258 |
1142 | TEAD4 | ARP38276_P050 | Ribas, R. et al. Members of the TEAD family of transcription factors regulate the expression of Myf5 in ventral somitic compartments. Dev. Biol. 355, 372-80 (2011). 21527258 | 21527258 |
1143 | TEAD4 | ARP38276_P050 | Screening with a novel cell-based assay for TAZ activators identifies a compound that enhances myogenesis in C2C12 cells and facilitates muscle repair in a muscle injury model. Mol Cell Biol. 34, 1607-21 (2014). 24550007 | 24550007 |
1144 | TEAD4 | ARP38276_P050 | Identification of Quinolinols as Activators of TEAD-Dependent Transcription. ACS Chem Biol. 14, 2909-2921 (2019). 31742995 | 31742995 |
1145 | TEAD4 | ARP38276_P050 | Yap/Taz inhibit goblet cell fate to maintain lung epithelial homeostasis. Cell Rep. 36, 109347 (2021) 34260916 | 34260916 |
1146 | Tecrl | ARP44592_P050 | TECRL deficiency results in aberrant mitochondrial function in cardiomyocytes. Commun Biol 470 5 1 May 2022 | 35577932 |
1147 | TET2 | OAEB00839 | Reduction of global 5-hydroxymethylcytosine is a poor prognostic factor in breast cancer patients, especially for an ER/PR-negative subtype. Breast Cancer Res. Treat. 153, 219-34 (2015). 26253945 | 26253945 |
1148 | TET2 | OAEB00839 | Ten-eleven translocation 1 dysfunction reduces 5-hydroxymethylcytosine expression levels in gastric cancer cells. Oncol Lett. 15, 278-284 (2018). 29285192 | 29285192 |
1149 | TF | OASG07301 | Endogenous morphine in SH-SY5Y cells and the mouse cerebellum. PLoS One. 3, e1641 (2008) 18327293 | 18327293 |
1150 | TFAM | OAAB00276 | miR-504 mediated down-regulation of nuclear respiratory factor 1 leads to radio-resistance in nasopharyngeal carcinoma. Oncotarget. 6, 15995-6018 (2015). 26201446 | 26201446 |
1151 | TFAM | ARP36992_P050 | TAZ links exercise to mitochondrial biogenesis via mitochondrial transcription factor A. Nat Commun 2022 1 13 653 35115527 | 35115527 |
1152 | Tfam | ARP36993_P050 | Propionate alleviates fatty acid-induced mitochondrial dysfunction, oxidative stress, and apoptosis by upregulating PPARG coactivator 1 alpha in hepatocytes. J Dairy Sci 2022 NULL NULL NULL 35181129 | 35181129 |
1153 | TFAP2A | OAAF01732 | Li, J. et al. A strategy to rapidly identify the functional targets of microRNAs by combining bioinformatics and mRNA cytoplasmic/nucleic ratios in culture cells. FEBS Lett. 584, 3198-202 (2010). 20547158 | 20547158 |
1154 | TFCP2L1 | OAAB09732 | The CDK1/TFCP2L1/ID2 cascade offers a novel combination therapy strategy in a preclinical model of bladder cancer. Exp Mol Med 2022 6 54 801-811 35729325 | 35729325 |
1155 | TG | OPSA10707 | Characterization of Regulatory B Cells in Graves' Disease and Hashimoto's Thyroiditis. PLoS One 2015 5 10 e0127949 26016954 | 26016954 |
1156 | TGFBR1 | OAAI00768 | Pericyte MyD88 and IRAK4 control inflammatory and fibrotic responses to tissue injury. J Clin Invest. 127, 321-334 (2017). 27869651 | 27869651 |
1157 | TGFBR1 | OAAI00768 | Phenotypic characterization of adenomyosis occurring at the inner and outer myometrium. PLoS One. 12, e0189522 (2017). 29253010 | 29253010 |
1158 | TGFBR1 | OAAI00768 | A pulsatile release platform based on photo-induced imine-crosslinking hydrogel promotes scarless wound healing. Nat Commun. 12, 1670 (2021) 33723267 | 33723267 |
1159 | TGFBR1 | OAAI00768 | Disulfiram Sensitizes a Therapeutic-Resistant Glioblastoma to the TGF-β Receptor Inhibitor. Int J Mol Sci 2021 19 22 NULL 34638842 | 34638842 |
1160 | TGM2 | OAAF01946 | Physiological, pathological, and structural implications of non-enzymatic protein-protein interactions of the multifunctional human transglutaminase 2. Cell. Mol. Life Sci. 72, 3009-35 (2015). 25943306 | 25943306 |
1161 | THIK-1 | ARP35347_P050 | Dysregulation of a potassium channel, THIK-1, targeted by caspase-8 accelerates cell shrinkage. Biochim. Biophys. Acta. 1863, 2766-2783 (2016). 27566292 | 27566292 |
1162 | Thoc4 | ARP43055_T100 | Ding, D., Enriquez-Algeciras, M., Dave, K. R., Perez-Pinzon, M. & Bhattacharya, S. K. The role of deimination in ATP5b mRNA transport in a transgenic mouse model of multiple sclerosis. EMBO Rep. 13, 230-6 (2012). 22261716 | 22261716 |
1163 | TLR2 | ARP30551_P050 | Expression of Toll-like receptors 2, 4 and 6 in equine endometrial epithelial cells: A comparative in situ and in vitro study. Res. Vet. Sci. 112, 34-41 (2017). 28119161 | 28119161 |
1164 | TLR2 | ARP30551_P050 | Expression of Toll-like receptors 2, 4 and 6 in different cell populations of the equine endometrium. Vet. Immunol. Immunopathol. 185, 7-13 (2017). 28242004 | 28242004 |
1165 | TM9SF1 | ARP44683_T100 | He, P. et al. High-throughput functional screening for autophagy-related genes and identification of TM9SF1 as an autophagosome-inducing gene. Autophagy 5, 52-60 (2009). 19029833 | 19029833 |
1166 | TM9SF1 | ARP44683_T100 | Extracellular vesicle-mediated EBAG9 transfer from cancer cells to tumor microenvironment promotes immune escape and tumor progression. Oncogenesis. 7, 7 (2018). 29362448 | 29362448 |
1167 | TMEM135 | ARP49773_P050 | Mouse Tmem135 mutation reveals a mechanism involving mitochondrial dynamics that leads to age-dependent retinal pathologies. Elife. 5, (2016). 27863209 | 27863209 |
1168 | TMTC2 | ARP49065_P050 | TRAIL sensitivity of nasopharyngeal cancer cells involves redox dependent upregulation of TMTC2 and its interaction with membrane caspase-3. Redox Biol 2021 NULL 48 102193 34839142 | 34839142 |
1169 | TNNI1 | ARP42117_P050 | Myostatin deficiency but not anti-myostatin blockade induces marked proteomic changes in mouse skeletal muscle. Proteomics. 16, 2019-27 (2016). 27214824 | 27214824 |
1170 | TNNI3 | ARP41391_P050 | Measurement of Myofilament-Localized Calcium Dynamics in Adult Cardiomyocytes and the Effect of Hypertrophic Cardiomyopathy Mutations. Circ Res. 124, 1228-1239 (2019). 30732532 | 30732532 |
1171 | TNRC5 | ARP34422_P050 | The whole-genome expression analysis of peripheral blood mononuclear cells from aspirin sensitive asthmatics versus aspirin tolerant patients and healthy donors after in vitro aspirin challenge. Respir. Res. 16, 147 (2015). 26646719 | 26646719 |
1172 | TNS1 | OAEB00321 | Gonadotropin-releasing hormone agonist induces downregulation of tensin 1 in women with endometriosis. Acta Obstet Gynecol Scand. 98, 222-231 (2019) 30312486 | 30312486 |
1173 | TPM2 | ARP48224_T100 | Abdul-Hussein, S., Rahl, K., Moslemi, A.-R. & Tajsharghi, H. Phenotypes of myopathy-related beta-tropomyosin mutants in human and mouse tissue cultures. PLoS One 8, e72396 (2013). 24039757 | 24039757 |
1174 | TRIM32 | ARP31692_P050 | Deficiency of the E3 ubiquitin ligase TRIM32 in mice leads to a myopathy with a neurogenic component. Hum Mol Genet. 18, 1353-67 (2009). 19155210 | 19155210 |
1175 | TRIM65 | OAAB08057 | LncRNA LINC00963 promotes colorectal cancer cell proliferation and metastasis by regulating miR‑1281 and TRIM65. Mol Med Rep. 24 (2021). 34498706 | 34498706 |
1176 | TRIM72 | OAEB00972 | Lack of MG53 in human heart precludes utility as a biomarker of myocardial injury or endogenous cardioprotective factor. Cardiovasc Res. 110, 178-87 (2016). 26790476 | 26790476 |
1177 | TRPA1 | ARP35205_P050 | Rohn, T. T., Catlin, L. W., Coonse, K. G. & Habig, J. W. Identification of an amino-terminal fragment of apolipoprotein E4 that localizes to neurofibrillary tangles of the Alzheimer’s disease brain. Brain Res. 1475, 106-15 (2012). 22905134 | 22905134 |
1178 | TRPA1 | ARP35205_P050 | Pierce, A. N., Ryals, J. M., Wang, R. & Christianson, J. A. Vaginal hypersensitivity and hypothalamic-pituitary-adrenal axis dysfunction as a result of neonatal maternal separation in female mice. Neuroscience 263, 216-30 (2014). 24462609 | 24462609 |
1179 | TRPA1 | ARP35205_P050 | TRPA1 mediates trigeminal neuropathic pain in mice downstream of monocytes/macrophages and oxidative stress. Brain. 139, 1361-77 (2016). 26984186 | 26984186 |
1180 | TRPA1 | ARP35205_P050 | TRPA1 receptor is upregulated in human oral lichen planus. Oral Dis. 23, 189-198 (2017). 27718297 | 27718297 |
1181 | TRPA1 | ARP35205_P050 | TRPA1 mediates damage of the retina induced by ischemia and reperfusion in mice. Cell Death Dis. 11, 633 (2020). 32801314 | 32801314 |
1182 | TRPA1 | ARP35205_P050 | Upregulation of extraneuronal TRPV1 expression in chronic rhinosinusitis with nasal polyps. Rhinology 2018 3 56 245-254 29476616 | 29476616 |
1183 | TRPA1 | ARP35205_P050 | No functional TRPA1 in cardiomyocytes. Acta Physiol (Oxf) e13659 232 4 August 2021 | 33819369 |
1184 | TRPM2 | ARP44380_P050 | TRPM2 mediates ischemic kidney injury and oxidant stress through RAC1. J Clin Invest. 124, 4989-5001 (2014). 25295536 | 25295536 |
1185 | TRPM5 | ARP35242_P050 | The Role of Cholecystokinin in Peripheral Taste Signaling in Mice. Front Physiol. 8, 866 (2017). 29163209 | 29163209 |
1186 | TRPV4 | ARP35416_P050 | Sampat, S. R. et al. Applied osmotic loading for promoting development of engineered cartilage. J. Biomech. 46, 2674-81 (2013). 24035014 | 24035014 |
1187 | TSC22D4 | ARP30107_T100 | Canterini, S., Bosco, A., De Matteis, V., Mangia, F. & Fiorenza, M. T. THG-1pit moves to nucleus at the onset of cerebellar granule neurons apoptosis. Mol. Cell. Neurosci. 40, 249-57 (2009). 19084601 | 19084601 |
1188 | TSC22D4 | ARP30107_T100 | Canterini, S. et al. Subcellular TSC22D4 localization in cerebellum granule neurons of the mouse depends on development and differentiation. Cerebellum 11, 28-40 (2012). 20878296 | 20878296 |
1189 | TSC22D4 | ARP30107_T100 | NRBP1-Containing CRL2/CRL4A Regulates Amyloid β Production by Targeting BRI2 and BRI3 for Degradation. Cell Rep. 30, 3478-3491.e6 (2020). 32160551 | 32160551 |
1190 | TSC22D4 | ARP37339_T100 | Canterini, S., Carletti, V., Nusca, S., Mangia, F. & Fiorenza, M. T. Multiple TSC22D4 iso-/phospho-glycoforms display idiosyncratic subcellular localizations and interacting protein partners. FEBS J. 280, 1320-9 (2013). 23305244 | 23305244 |
1191 | TSC22D4 | ARP37339_T100 | GILZ-dependent modulation of mTORC1 regulates spermatogonial maintenance. Development. 145, (2018). 30126904 | 30126904 |
1192 | TSG101 | ARP37310_T100 | Isolation of Exosomes and Microvesicles from Cell Culture Systems to Study Prion Transmission. Methods Mol. Biol. 1545, 153-176 (2017). 27943213 | 27943213 |
1193 | TSPO | OALA05219 | Organoid-derived C-Kit+/SSEA4- human retinal progenitor cells promote a protective retinal microenvironment during transplantation in rodents. Nat Commun. 10, 1205 (2019). 30872578 | 30872578 |
1194 | TTK | OAAF01564 | Targeting dual specificity protein kinase TTK attenuates tumorigenesis of glioblastoma. Oncotarget. 9, 3081-3088 (2018). 29423030 | 29423030 |
1195 | TTRAP | ARP33010_P050 | Xu, G.-L. et al. TTRAP is a novel PML nuclear bodies-associated protein. Biochem. Biophys. Res. Commun. 375, 395-8 (2008). 18706885 | 18706885 |
1196 | TTRAP | ARP33010_P050 | Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan. Nucleic Acids Res. (2016). 27789688 | 27789688 |
1197 | TTYH3 | ARP49946_P050 | TTYH3 Modulates Bladder Cancer Proliferation and Metastasis via FGFR1/H-Ras/A-Raf/MEK/ERK Pathway. Int J Mol Sci NULL 23 18 September 2022 | 36142409 |
1198 | TUBB2A | ARP40177_P050 | Crystal Structure of the SPOC Domain of the Arabidopsis Flowering Regulator FPA. PLoS ONE. 11, e0160694 (2016). 27513867 | 27513867 |
1199 | TWIST1 | ARP37997_T100 | Guha, P. et al. Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, a9 nicotinic acetylcholine receptor and STAT3. Breast Cancer Res. Treat. 145, 5-22 (2014). 24668500 | 24668500 |
1200 | TWIST1 | ARP37997_T100 | Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor. Cancer Cell. 26, 222-34 (2014). 25117710 | 25117710 |
1201 | TYR1 | ARP44315_P050 | Horibe, I. et al. Induction of melanogenesis by 4’-O-methylated flavonoids in B16F10 melanoma cells. J. Nat. Med. 67, 705-10 (2013). 23208771 | 23208771 |
1202 | U1A | ARP40275_P050 | Wang, E., Mueller, W. F., Hertel, K. J. & Cambi, F. G Run-mediated recognition of proteolipid protein and DM20 5’ splice sites by U1 small nuclear RNA is regulated by context and proximity to the splice site. J. Biol. Chem. 286, 4059-71 (2011). 21127064 | 21127064 |
1203 | UBE2E1 | ARP43012_P050 | Regulation of canonical Wnt signalling by the ciliopathy protein MKS1 and the E2 ubiquitin-conjugating enzyme UBE2E1. Elife 2022 NULL 11 NULL 35170427 | 35170427 |
1204 | UBE2E2 | ARP43437_P050 | Hans, F. et al. UBE2E ubiquitin-conjugating enzymes and ubiquitin isopeptidase Y regulate TDP-43 protein ubiquitination. J. Biol. Chem. 289, 19164-79 (2014). 24825905 | 24825905 |
1205 | Ube2n | ARP34089_T100 | Xu, B. J. et al. Quantitative analysis of the secretome of TGF-beta signaling-deficient mammary fibroblasts. Proteomics 10, 2458-70 (2010). 20405477 | 20405477 |
1206 | UBE2T | ARP43145_P050 | CaMKII-δ9 Induces Cardiomyocyte Death to Promote Cardiomyopathy and Heart Failure. Front Cardiovasc Med 2022 NULL 8 820416 35127874 | 35127874 |
1207 | ULK1 | OABF01248 | The Combination of Fasting, Acute Resistance Exercise, and Protein Ingestion Led to Different Responses of Autophagy Markers in Gastrocnemius and Liver Samples. Nutrients. 12, (2020). 32121154 | 32121154 |
1208 | ULK1 | OABF01248 | Mir214-3p and Hnf4a/Hnf4α reciprocally regulate Ulk1 expression and autophagy in nonalcoholic hepatic steatosis. Autophagy. NULL, 1-17 (2020). 33078654 | 33078654 |
1209 | ULK1 | OABF01248 | Genetic deletion of IL-6 increases CK-MB, a classic cardiac damage marker, and decreases UPRmt genes after exhaustive exercise. Cell Biochem Funct 369-378 40 4 June 2022 | 35411956 |
1210 | ULK1 | OABF01248 | Chronic rapamycin treatment decreases hepatic IL-6 protein, but increases autophagy markers as a protective effect against the overtraining-induced tissue damage. Clin Exp Pharmacol Physiol 893-902 49 8 August 2022 | 35637552 |
1211 | UPF3B | ARP40998_T100 | RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis. Sci Rep. 7, 41517 (2017). 28128343 | 28128343 |
1212 | UPF3B | ARP40998_T100 | Premature termination codon readthrough in human cells occurs in novel cytoplasmic foci and requires UPF proteins. J Cell Sci. 130, 3009-3022 (2017). 28743738 | 28743738 |
1213 | USE1 | ARP39361_P050 | Serologic markers of effective tumor immunity against chronic lymphocytic leukemia include nonmutated B-cell antigens. Cancer Res. 70, 1344-55 (2010). 20124481 | 20124481 |
1214 | VARS | ARP46151_P050 | Duarte, M. & Videira, A. Defective valyl-tRNA synthetase hampers the mitochondrial respiratory chain in Neurospora crassa. Biochem. J. 448, 297-306 (2012). 22957697 | 22957697 |
1215 | VDAC1 | ARP35122_T100 | Chen, S. et al. Reduced expression of lamin A/C results in modified cell signaling and metabolism coupled with changes in expression of structural proteins. J. Proteome Res. 8, 5196-211 (2009). 19775189 | 19775189 |
1216 | VDAC1 | ARP35122_T100 | Arduíno, D. M. et al. Mitochondrial metabolism in Parkinson’s disease impairs quality control autophagy by hampering microtubule-dependent traffic. Hum. Mol. Genet. 21, 4680-702 (2012). 22843496 | 22843496 |
1217 | VDAC1 | ARP35122_T100 | Rousset, F., Nguyen, M. V. C., Grange, L., Morel, F. & Lardy, B. Heme oxygenase-1 regulates matrix metalloproteinase MMP-1 secretion and chondrocyte cell death via Nox4 NADPH oxidase activity in chondrocytes. PLoS One 8, e66478 (2013). 23840483 | 23840483 |
1218 | VDAC2 | ARP35123_P050 | Hrabakova, R. et al. Cancer cell resistance to aurora kinase inhibitors: identification of novel targets for cancer therapy. J. Proteome Res. 12, 455-69 (2013). 23151231 | 23151231 |
1219 | VDAC3 | ARP35180_P050 | Majumder, S., Slabodnick, M., Pike, A., Marquardt, J. & Fisk, H. A. VDAC3 regulates centriole assembly by targeting Mps1 to centrosomes. Cell Cycle 11, 3666-78 (2012). 22935710 | 22935710 |
1220 | VDAC3 | ARP35180_P050 | Majumder, S. & Fisk, H. A. VDAC3 and Mps1 negatively regulate ciliogenesis. Cell Cycle 12, 849-58 (2013). 23388454 | 23388454 |
1221 | VDAC3 | ARP35180_P050 | Non-Overlapping Distributions and Functions of the VDAC Family in Ciliogenesis. Cells. 4, 331-53 (2015). 26264029 | 26264029 |
1222 | WASF3 | OAEC03197 | Li, J. et al. A strategy to rapidly identify the functional targets of microRNAs by combining bioinformatics and mRNA cytoplasmic/nucleic ratios in culture cells. FEBS Lett. 584, 3198-202 (2010). 20547158 | 20547158 |
1223 | WDR45 | OAAB09622 | TRAPPC11 functions in autophagy by recruiting ATG2B-WIPI4/WDR45 to preautophagosomal membranes. Traffic 325-345 20 5 May 2019 | 30843302 |
1224 | Wnt2B | ARP41254_P050 | Chigita, S. et al. CD82 inhibits canonical Wnt signalling by controlling the cellular distribution of beta-catenin in carcinoma cells. Int. J. Oncol. 41, 2021-8 (2012). 23076981 | 23076981 |
1225 | Wnt7b | ARP41291_P050 | Gore, A. J., Deitz, S. L., Palam, L. R., Craven, K. E. & Korc, M. Pancreatic cancer-associated retinoblastoma 1 dysfunction enables TGF-beta to promote proliferation. J. Clin. Invest. 124, 338-52 (2014). 24334458 | 24334458 |
1226 | WT1 | OAAN00281 | Antileukaemic Cell Proliferation and Cytotoxic Activity of Edible Golden Cordyceps (Cordyceps militaris) Extracts. Evid Based Complement Alternat Med 2022 NULL 2022 5347718 35497915 | 35497915 |
1227 | XDH | OAAB05869 | Human placental renin-angiotensin system in normotensive and pre-eclamptic pregnancies at high altitude and after acute hypoxia-reoxygenation insult. J Physiol. 594, 1327-40 (2016). 26574162 | 26574162 |
1228 | XPOT | ARP40711_P050 | The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals. Elife. 10, NULL (2021) 33646118 | 33646118 |
1229 | YAP1 | ARP50530_P050 | Allelic Expression Imbalance Analysis Identified YAP1 Amplification in p53- Dependent Osteosarcoma. Cancers (Basel). 13 (2021). 33803512 | 33803512 |
1230 | YTHDF2 | ARP67917_P050 | The RNA m6A Reader YTHDF2 Maintains Oncogene Expression and Is a Targetable Dependency in Glioblastoma Stem Cells. Cancer Discov 2021 2 11 480-499 33023892 | 33023892 |
1231 | ZBTB32 | OACA06573 | ZBTB32 performs crosstalk with the glucocorticoid receptor and is crucial in glucocorticoid responses to starvation. iScience 2021 7 24 102790 34337361 | 34337361 |
1232 | Zbtb43 | ARP39048_P050 | Z-DNA is remodelled by ZBTB43 in prospermatogonia to safeguard the germline genome and epigenome. Nat Cell Biol 1141-1153 24 7 July 2022 | 35787683 |
1233 | ZEB1 | ARP30976_P050 | Li, J. et al. A strategy to rapidly identify the functional targets of microRNAs by combining bioinformatics and mRNA cytoplasmic/nucleic ratios in culture cells. FEBS Lett. 584, 3198-202 (2010). 20547158 | 20547158 |
1234 | ZEB2 | ARP39141_P050 | Rogers, C. D., Saxena, A. & Bronner, M. E. Sip1 mediates an E-cadherin-to-N-cadherin switch during cranial neural crest EMT. J. Cell Biol. 203, 835-47 (2013). 24297751 | 24297751 |
1235 | ZEB2 | ARP39141_P050 | Guan, H. et al. Down-regulation of miR-144 promotes thyroid cancer cell invasion by targeting ZEB1 and ZEB2. Endocrine. doi:10.1007/s12020-014-0326-7 (2014). 24968735 | 24968735 |
1236 | ZFP191 | ARP33519_P050 | Lv, L. et al. Zinc finger protein 191 deficiency attenuates vascular smooth muscle cell proliferation, migration, and intimal hyperplasia after endovascular arterial injury. J. Vasc. Surg. (2013). doi:10.1016/j.jvs.2013.03.049 23755975 | 23755975 |
1237 | ZFX | ARP33498_P050 | Zha, W., Cao, L., Shen, Y. & Huang, M. Roles of Mir-144-ZFX pathway in growth regulation of non-small-cell lung cancer. PLoS One 8, e74175 (2013). 24066116 | 24066116 |
1238 | ZIC2 | ARP35821_P050 | Addiction of pancreatic cancer cells to zinc-finger transcription factor ZIC2. Oncotarget. 6, 28257-68 (2015). 26318045 | 26318045 |
1239 | ZIC2 | ARP35821_P050 | ZIC2-dependent OCT4 activation drives self-renewal of human liver cancer stem cells. J. Clin. Invest. 125, 3795-808 (2015). 26426078 | 26426078 |
1240 | ZIC2 | ARP35821_P050 | The long noncoding RNA lncZic2 drives the self-renewal of liver tumor-initiating cells via the protein kinase C substrates MARCKS and MARCKSL1. J Biol Chem. 293, 7982-7992 (2018). 29588366 | 29588366 |
1241 | ZIC5 | OAEB00858 | AR-regulated ZIC5 contributes to the aggressiveness of prostate cancer. Cell Death Discov 393 8 1 September 2022 | 36127329 |
1242 | ZIP5 | ARP44143_P050 | Zinc Transport Differs in Rat Spermatogenic Cell Types and Is Affected by Treatment with Cyclophosphamide. Biol. Reprod. 95, 22 (2016). 27281708 | 27281708 |
1243 | ZNF142 | ARP38554_P050 | AMP-Activated Protein Kinase Regulates the Cell Surface Proteome and Integrin Membrane Traffic. PLoS ONE. 10, e0128013 (2015). 26010094 | 26010094 |
1244 | ZNF230 | ARP34554_P050 | Liu, Y. et al. A new mutant transcript generated in Znf230 exon 2 knockout mice reveals a potential exon structure in the targeting vector sequence. Acta Biochim. Biophys. Sin. (Shanghai). 45, 123-8 (2013). 23196134 | 23196134 |
1245 | ZNF318 | ARP32523_P050 | Rad52 mediates class-switch DNA recombination to IgD. Nat Commun 2022 1 13 980 35190531 | 35190531 |
1246 | ZNF384 | OACA04063 | ZNF384-fusion proteins have high affinity for the transcriptional coactivator EP300 and aberrant transcriptional activities. FEBS Lett 2151-2161 593 16 August 2019 | 31234226 |
1247 | ZNF580 | ARP39236_P050 | Hoffmann, C. J. et al. Suppression of zinc finger protein 580 by high oxLDL/LDL-ratios is followed by enhanced expression of endothelial IL-8. Atherosclerosis 216, 103-8 (2011). 21310414 | 21310414 |
1248 | ZNF580 | ARP39236_P050 | ZNF580 - a brake on Interleukin-6. J Inflamm (Lond). 15, 20 (2018). 30386182 | 30386182 |
1249 | OAMA00562 | Cytomegalovirus proteins, maternal pregnancy cytokines, and their impact on neonatal immune cytokine profiles and acute lymphoblastic leukemogenesis in children. Haematologica 2022 NULL NULL NULL 35638549 | 35638549 | |
1250 | OPMA04848 | A vaccine inducing solely cytotoxic T lymphocytes fully prevents Zika virus infection and fetal damage. Cell Rep 2021 6 35 109107 33979612 | 33979612 | |
1251 | OPMA04522 | Protective heterologous T cell immunity in COVID-19 induced by the trivalent Measles-Mumps-Rubella and Tetanus-Diptheria-Pertussis vaccine antigens. Med (N Y) 2021 NULL NULL NULL 34414383 | 34414383 | |
1252 | OAMA00655 | Defining the specificity of recombinant human erythropoietin confirmation in equine samples by liquid chromatography-tandem mass spectrometry. Drug Test Anal 676-689 14 4 April 2022 | 34898016 | |
1253 | OAMA02979 | Long tail fibres of the novel broad-host-range T-even bacteriophage S16 specifically recognize Salmonella OmpC. Mol Microbiol 818-34 87 4 February 2013 | 23289425 |