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Signaling Pathways

Introduction to Signaling Pathways

Signaling pathways serve as the communication networks that transmit vital information, orchestrating processes such as cell growth, differentiation, and reactions to external stimuli. Researchers study the molecular construct, interactions, and feedback mechanisms dictating signaling events, aiming to reveal fundamental principles governing cellular communication. 

In signaling pathways research, scientists investigate the intricate language of molecular signals. New knowledge of receptors, ligands, kinases, and secondary messengers provide profound insights into developmental biology, disease mechanisms, and potential therapeutic interventions.  

This research leads to pioneering breakthroughs in targeted therapies, precision medicine approaches, and innovative drug discovery strategies, offering transformative solutions for a wide range of diseases and disorders. In essence, the study of signaling pathways is a cornerstone in advancing both basic science and clinical applications, paving the way for advancements in biology and medicine. 

With a catalog boasting over 15,000 protein targets, trial sizes for exploring emerging projects, and advanced validation methods, Aviva is dedicated to supporting researchers as they pave the way for new discoveries and breakthroughs in Signaling Pathway research. 


Featured Products

WNT3A ELISA Kit (Human) (OKCD09406) INPP5D Antibody - C-terminal region (ARP61033_P050) NOTCH1 Recombinant Monoclonal Antibody [4F6] (OACA12628)

Sample Type: WNT3A ELISA Standard Curve

WNT3A ELISA Kit (Human) (OKCD09406) - Standard Curve. Colorimetric, OD 450 nm. ELISA Kit Range: 0.156-10ng/mL. Pre-coated with an antibody specific to Wingless Type MMTV Integration Site Family, Member 3A (WNT3A), click here

Sample Type: Lysates of WT and INPP5D KO iPSC-derived microglia

INPP5D Antibody - C-terminal region (ARP61033_P050) - Lysates of WT and INPP5D KO iPSC-derived microglia were prepared, and 10 μg of protein were processed for Western blot. Antibody dilution 1/500. Ponceau S staining to verify protein transfer, click here

Sample Type: HepG2, THP-1 , and HL-60 Whole Cell Lysate

NOTCH1 Recombinant Monoclonal Antibody [4F6] (OACA12628) - Western Blot Positive WB detected in: HepG2 whole cell lysate, THP-1 whole cell lysate, HL-60 whole cell lysate. All lanes: Notch1 antibody at 1:1000. Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 273 kDa Observed band size: 120 kDa.  click here