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ANXA3 antibody - N-terminal region (ARP36578_T100)

100 ul
$249.00
In Stock

Conjugation Options

ARP36578_T100-FITC Conjugated

ARP36578_T100-HRP Conjugated

ARP36578_T100-Biotin Conjugated

Gene Symbol:
ANXA3
NCBI Gene Id:
306
Official Gene Full Name:
Annexin A3
Protein Name:
Annexin A3
Swissprot Id:
P12429
Protein Accession #:
NP_005130
Nucleotide Accession #:
NM_005139
Alias Symbols:
ANX3
Replacement Item:
This antibody may replace item sc-101511, HPA013398
Description of Target:
The ANXA3 gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.
Protein Size (# AA):
323
Molecular Weight:
36kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Protein A purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express ANXA3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express ANXA3.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human ANXA3
Species Reactivity:
Horse, Human, Rabbit
Predicted Homology Based on Immunogen Sequence:
Dog: 79%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 93%; Rat: 79%
Complete computational species homology data:
Anti-ANXA3 (ARP36578_T100)
Peptide Sequence:
Synthetic peptide located within the following region: MASIWVGHRGTVRDYPDFSPSVDAEAIQKAIRGIGTDEKMLISILTERSN
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
UBC; ATF2; SNAP23; STXBP2; STX4; ANXA11; ANXA4; ISG15; EMG1; IGSF21; UBR1; UNC119; TP53; REG3A;
Blocking Peptide:
For anti-ANXA3 (ARP36578_T100) antibody is Catalog # AAP36578 (Previous Catalog # AAPP07811)
Datasheets/Manuals:
Printable datasheet for anti-ANXA3 (ARP36578_T100) antibody
Target Reference:
Sekar,M.C., et al., (1996) J. Biol. Chem. 271 (14), 8295-8299
Publications:

Seliger, B. et al. Combined analysis of transcriptome and proteome data as a tool for the identification of candidate biomarkers in renal cell carcinoma. Proteomics 9, 1567-81 (2009). IHC, WB, Horse, Human, Rabbit 19235166

Schordan, S. et al. Alterations of the podocyte proteome in response to high glucose concentrations. Proteomics 9, 4519-28 (2009). IHC, WB, Horse, Human, Rabbit 19688724

Bianchi, C. et al. Primary cell cultures from human renal cortex and renal-cell carcinoma evidence a differential expression of two spliced isoforms of Annexin A3. Am. J. Pathol. 176, 1660-70 (2010). IHC, WB, Horse, Human, Rabbit 20167856

Meyer-Schwesinger, C. et al. Nephrotic syndrome and subepithelial deposits in a mouse model of immune-mediated anti-podocyte glomerulonephritis. J. Immunol. 187, 3218-29 (2011). IHC, WB, Horse, Human, Rabbit 21844386

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