ANXA3 Antibody - N-terminal region (ARP36578_T100)

Data Sheet
Product Number ARP36578_T100
Product Page
Name ANXA3 Antibody - N-terminal region (ARP36578_T100)
Protein Size (# AA) 323 amino acids
Molecular Weight 36 kDa
NCBI Gene Id 306
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Annexin A3
Alias Symbols ANX3
Peptide Sequence Synthetic peptide located within the following region: MASIWVGHRGTVRDYPDFSPSVDAEAIQKAIRGIGTDEKMLISILTERSN
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Sekar,M.C., et al., (1996) J. Biol. Chem. 271 (14), 8295-8299
Description of Target The ANXA3 gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.
Protein Interactions UBC; ATF2; SNAP23; STXBP2; STX4; ANXA11; ANXA4; ISG15; EMG1; IGSF21; UBR1; UNC119; TP53; REG3A;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Enhanced Validation
Relative Expression (Western Blot) Avivasheild
Datasheets/Manuals Printable datasheet for anti-ANXA3 (ARP36578_T100) antibody
Blocking Peptide For anti-ANXA3 (ARP36578_T100) antibody is Catalog # AAP36578 (Previous Catalog # AAPP07811)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human ANXA3
Uniprot ID P12429
Protein Name Annexin A3

Bianchi, C. et al. Primary cell cultures from human renal cortex and renal-cell carcinoma evidence a differential expression of two spliced isoforms of Annexin A3. Am. J. Pathol. 176, 1660-70 (2010). 20167856

Meyer-Schwesinger, C. et al. Nephrotic syndrome and subepithelial deposits in a mouse model of immune-mediated anti-podocyte glomerulonephritis. J. Immunol. 187, 3218-29 (2011). 21844386

Schordan, S. et al. Alterations of the podocyte proteome in response to high glucose concentrations. Proteomics 9, 4519-28 (2009). 19688724

Seliger, B. et al. Combined analysis of transcriptome and proteome data as a tool for the identification of candidate biomarkers in renal cell carcinoma. Proteomics 9, 1567-81 (2009). 19235166

Protein Accession # NP_005130
Purification Protein A purified
Nucleotide Accession # NM_005139
Tested Species Reactivity Human
Gene Symbol ANXA3
Predicted Species Reactivity Human, Horse, Rabbit
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Dog: 79%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 93%; Rat: 79%
Image 1
Human Fetal Lung
Host: Rabbit
Target Name: ANXA3
Sample Tissue: Human Fetal Lung
Antibody Dilution: 1.0ug/ml
Image 2
Human Spleen
Human Spleen
Image 3
Western Blot
25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment.

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