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- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for OAAB17792 |
|---|
| Predicted Species Reactivity | Human, Mouse, Rat |
|---|---|
| Product Format | Liquid. Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| Clonality | Monoclonal |
| Isotype | IgG1, kappa |
| Host | Mouse |
| Application | WB |
| Reconstitution and Storage | Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | This USP5 antibody is generated from a mouse immunized with a recombination protein from the human region of human USP5. |
| Purification | This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Application Info | WB: 1:2000 |
| Reference | Falquet L., et al.FEBS Lett. 376:233-237(1995). Ansari-Lari M.A., et al.Genome Res. 6:314-326(1996). Ansari-Lari M.A., et al.Genome Res. 7:268-280(1997). Tashayev V.L., et al.Submitted (NOV-1995) to the EMBL/GenBank/DDBJ databases. Mural R.J., et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. |
| Gene Symbol | USP5 |
|---|---|
| Alias Symbols | ISOT |
| NCBI Gene Id | 8078 |
| Description of Target | Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys- 63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition. |
| Uniprot ID | P45974 |
| Molecular Weight | 96 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "USP5 Antibody (OAAB17792)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".
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How long will it take to receive "USP5 Antibody (OAAB17792)"?
This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".
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What buffer format is "USP5 Antibody (OAAB17792)" provided in?
This item is provided in "Liquid. Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "USP5 Antibody (OAAB17792)"?
This target may also be called "ISOT" in publications.
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What is the shipping cost for "USP5 Antibody (OAAB17792)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "USP5 Antibody (OAAB17792)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "USP5 Antibody (OAAB17792)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "96 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "USP5 Antibody (OAAB17792)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "USP5"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "USP5"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "USP5"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "USP5"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "USP5"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "USP5"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
