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- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
Datasheets/Manuals | Printable datasheet for TARDBP Antibody (OACA07038) (OACA07038) |
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Predicted Species Reactivity | Human|Mouse |
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Product Format | Liquid |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay|Immunohistochemistry|Immunoprecipitation|Western blot |
Reconstitution and Storage | -20°C or -80°C |
Immunogen | Recombinant Human TAR DNA-binding protein 43 protein (1-260AA) |
Purification | Affinity Purified |
Preservative | 0.02% sodium azide |
Formulation | PBS with, 50% glycerol, pH7.3. |
Reference | [1]"Novel TARDBP mutations in Nordic ALS patients."Chiang H.H., Andersen P.M., Tysnes O.B., Gredal O., Christensen P.B., Graff C.J. Hum. Genet. 57:316-319(2012). [2]"High frequency of the TARDBP p.Ala382Thr mutation in Sardinian patients with amyotrophic lateral sclerosis."Orru S., Manolakos E., Orru N., Kokotas H., Mascia V., Carcassi C., Petersen M.B.Clin. Genet. 81:172-178(2012). [3]"Large proportion of amyotrophic lateral sclerosis cases in Sardinia due to a single founder mutation of the TARDBP gene."Chio A., Borghero G., Pugliatti M., Ticca A., Calvo A., Moglia C., Mutani R., Brunetti M., Ossola I., Marrosu M.G., Murru M.R., Floris G., Cannas A., Parish L.D., Cossu P., Abramzon Y., Johnson J.O., Nalls M.A. Restagno G.Arch. Neurol. 68:594-598(2011). |
Gene Symbol | TARDBP |
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Gene Full Name | TAR DNA binding protein |
Alias Symbols | ALS10;TAR DNA-binding protein 43;TAR DNA-binding protein-43;TDP-43. |
NCBI Gene Id | 23435 |
Protein Name | TAR DNA-binding protein 43 |
Description of Target | DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR. |
Uniprot ID | Q13148 |
Protein Accession # | NP_031401 |
Nucleotide Accession # | NM_007375 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "TARDBP Antibody (OACA07038)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse".
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How long will it take to receive "TARDBP Antibody (OACA07038)"?
This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".
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What buffer format is "TARDBP Antibody (OACA07038)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "TARDBP Antibody (OACA07038)"?
This target may also be called "ALS10;TAR DNA-binding protein 43;TAR DNA-binding protein-43;TDP-43." in publications.
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What is the shipping cost for "TARDBP Antibody (OACA07038)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "TARDBP Antibody (OACA07038)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "TARDBP Antibody (OACA07038)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "TARDBP Antibody (OACA07038)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "TARDBP"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "TARDBP"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "TARDBP"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "TARDBP"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "TARDBP"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "TARDBP"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.