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TARDBP Antibody (OAPB00552)

0.1 mg
$375.00
In Stock
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Conjugation Options

OAPB00552-FITC Conjugated

OAPB00552-HRP Conjugated

OAPB00552-Biotin Conjugated

Predicted Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid. PBS containing 0.02% sodium azide.
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
ELISA, WB, ICC, IF
Reconstitution and Storage:
TDP43 antibody can be stored at 4C for three months and-20C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Gene Symbol:
TARDBP
Official Gene Full Name:
TAR DNA-binding protein 43
NCBI Gene Id:
23435
Protein Name:
TAR DNA-binding protein 43
Swissprot Id:
Q13148
Protein Accession #:
NP_031401.1
Nucleotide Accession #:
NM_007375.3
Replacement Item:
This antibody may replace item sc-100871 from Santa Cruz Biotechnology.
Description of Target:
(NT) TAR DNA binding protein
Purification:
Affinity chromatography purified via peptide column
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express TARDBP.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express TARDBP.
Immunogen:
The immunogen for anti-TDP43 antibody: antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human TDP43.
Predicted Homology Based on Immunogen Sequence:
Human; Mouse; Rat
Blocking Peptide:
For anti-TARDBP (OAPB00552) antibody is Catalog # OEPB02674
Datasheets/Manuals:
Printable datasheet for anti-TARDBP (OAPB00552) antibody
Specificity:
At least two isoforms are known to exist for this protein; this TDP43 antibody will recognize both isoforms.
Application Info:
WB 0.5~2 ug/ml
ICC 5 ug/ml
IF 20 ug/ml
Other Applications Image 1 Data:
Immunocytochemistry of TDP43 in HeLa cells with TDP43 antibody at 5 ug/mL.
Target Reference:
1. Ou SH, Wu F, Garcia-Martinez LF, et al. Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs. J. Virol.1995; 69:3584-96.;
2. Buratti E, Dork T, Zuccato E, et al. Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping. EMBO J.2001; 20:1774-84.;
3. Neumann M, Sampathu DM, Kwong LK, et al. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 2006; 314:42-3.;

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