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TARDBP Antibody (OAPA00316)

5ug
$100.00
In Stock
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Product Format:
1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
Clonality:
Monoclonal
Clone:
Pk1B8AT.
Isotype:
Mouse IgG1 heavy chain and kappa light chain.
Host:
Mouse
Application:
ELISA, WB, IHC
:::
Product Type: Mouse Anti Human Monoclonal.
:::
Product Introduction: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome which produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. TARDBP is a transcriptional repressor which binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, TARDBP regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Reconstitution and Storage:
For periods up to 1 month store at 4C, for longer periods of time, store at -20C. Prevent freeze thaw cycles.
Stability: 12 months at -20C. 1 month at 4C.
Gene Symbol:
TARDBP
NCBI Gene Id:
23435
Protein Name:
TAR DNA-binding protein 43
Swissprot Id:
Q13148
Alias Symbols:
ALS10, TDP-43,
Replacement Item:
This antibody may replace item sc-100871 from Santa Cruz Biotechnology.
Description of Target:
Mouse Anti Human TAR DNA-binding protein 43
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express TARDBP.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express TARDBP.
Immunogen:
The immunogen for anti-TARDBP antibody: anti-human TARDBP mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TARDBP amino acids 1-260 purified from E. coli.
Datasheets/Manuals:
Printable datasheet for anti-TARDBP antibody - OAPA00316
Purity:
TARDBP antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Application Info:
TARDBP antibody has been tested by ELISA, Western blot and immunohistochemistry analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot is 1:1,000~1:2,000 and immunohistochemistry analysis is 1:50~100. Recommended starting dilution for Western blot is 1:1,000 and Immunohistochemistry is 1:50.

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