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Now Offering Over 102,157 Antibodies & 44,722 Antigens!

TAP1 antibody - middle region (ARP43628_P050)

100 ul
$319.00
In Stock

Conjugation Options

ARP43628_P050-FITC Conjugated

ARP43628_P050-HRP Conjugated

ARP43628_P050-Biotin Conjugated

Gene Symbol:
TAP1
NCBI Gene Id:
6890
Official Gene Full Name:
Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
Protein Name:
Antigen peptide transporter 1
Swissprot Id:
Q03518
Protein Accession #:
NP_000584
Nucleotide Accession #:
NM_000593
Alias Symbols:
ABC17, ABCB2, APT1, D6S114E, FLJ26666, FLJ41500, PSF1, RING4, TAP1*0102N, TAP1N, PSF-1
Replacement Item:
This antibody may replace item sc-11464 from Santa Cruz Biotechnology.
Description of Target:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). TAP1 is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. TAP1 is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble.The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Protein Size (# AA):
808
Molecular Weight:
87kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express TAP1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express TAP1.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human TAP1
Species Reactivity:
Cow, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Predicted Homology Based on Immunogen Sequence:
Cow: 92%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 92%; Rat: 100%; Zebrafish: 83%
Complete computational species homology data:
Anti-TAP1 (ARP43628_P050)
Peptide Sequence:
Synthetic peptide located within the following region: LVTFVLYQMQFTQAVEVLLSIYPRVQKAVGSSEKIFEYLDRTPRCPPSGL
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
UBC; MUL1; TDP2; SFXN1; GADD45GIP1; MRPL40; MCAT; SRSF3; SDHA; ABCD3; CYC1; PSMB8; TAPBP; TAP2; HLA-A; PDIA3; CALR; B2M; PDIA2; KRTAP4-12; MDFI; PSMB5; HLA-F; HLA-G; ESR1; COPG1; COPB1;
Blocking Peptide:
For anti-TAP1 (ARP43628_P050) antibody is Catalog # AAP43628 (Previous Catalog # AAPP11617)
Datasheets/Manuals:
Printable datasheet for anti-TAP1 (ARP43628_P050) antibody
Sample Type Confirmation:

TAP1 is supported by BioGPS gene expression data to be expressed in HeLa

Target Reference:
Soundravally,R. (2008) Scand. J. Immunol. 67 (6), 618-625

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