| Sku |
AAP43628 |
| Old sku |
AAPP11617 |
| Price |
$99.00 |
| Name |
TAP1 Peptide - middle region (AAP43628) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
TAP1 |
| Alias symbols |
ABC17, ABCB2, APT1, D6S114E, FLJ26666, FLJ41500, PSF1, RING4, TAP1*0102N, TAP1N, PSF-1 |
| Gene id |
6890 |
| Description of target |
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). TAP1 is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. TAP1 is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble.The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Swissprot id |
Q03518 |
| Protein accession num |
NP_000584 |
| Nucleotide accession num |
NM_000593 |
| Protein size |
808 amino acids |
| Molecular weight |
87kDa |
| Application |
IHC, WB |
| Partner proteins |
ESR1,HLA-F,HLA-G,KRTAP4-12,MDFI,PDIA3,PSMB5,PSMB8,TAP2,TAPBP,COPB1,COPG,HLA-A,HLA-G,KRTAP4-12,MDFI,PDIA3,TAP2,TAPBP |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Soundravally,R. (2008) Scand. J. Immunol. 67 (6), 618-625 |
| Description |
This is a synthetic peptide designed for use in combination with anti-TAP1 antibody (Catalog #: ARP43628_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
