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RNF31 Antibody - middle region : FITC (ARP43241_P050-FITC)

100 ul
$319.00
In Stock
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Conjugation Options

ARP43241_P050 Unconjugated

ARP43241_P050-HRP Conjugated

ARP43241_P050-Biotin Conjugated

Predicted Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer.
Clonality:
Polyclonal
Host:
Rabbit
Conjugation:
FITC (FAM): Excitation 495 nm/ Emission 520 nm
Application:
WB
Reconstitution and Storage:
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Gene Symbol:
RNF31
Official Gene Full Name:
Ring finger protein 31
NCBI Gene Id:
55072
Protein Name:
E3 ubiquitin-protein ligase RNF31
Swissprot Id:
Q96EP0
Protein Accession #:
NP_060469
Nucleotide Accession #:
NM_017999
Alias Symbols:
FLJ10111, FLJ23501, MGC19975, ZIBRA, HOIP
Replacement Item:
This antibody may replace item sc-153046 from Santa Cruz Biotechnology.
Description of Target:
PWP2 contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions.The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions.
Protein Size (# AA):
1072
Molecular Weight:
120kDa
Purification:
Affinity Purified
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express RNF31.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express RNF31.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human RNF31
Predicted Homology Based on Immunogen Sequence:
Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 100%
Complete computational species homology data:
Anti-RNF31 (ARP43241_P050)
Peptide Sequence:
Synthetic peptide located within the following region: SLINAHSLDPATLYEVEELETATERYLHVRPQPLAGEDPPAYQARLLQKL
Concentration:
0.5 mg/ml
Protein Interactions:
CCDC24; VASN; KRTAP9-2; TSSC4; UBC; SNRPC; PRKCA; AES; PITX1; KIF1A; SHARPIN; RBCK1; RNF31; MALT1; VCP; OTULIN; IRAK1; ESR1; Ikbkg; CCDC14; WRNIP1; AKAP8L; TRAF2; TNF; NDUFA8; BIRC2; NOD2; BIRC3; HCVgp1; SOCS3; SMAD3; NOS3; UBE2D3; UBE2D1; TNFAIP3; GFI1B;
Blocking Peptide:
For anti-RNF31 (ARP43241_P050-FITC) antibody is Catalog # AAP43241 (Previous Catalog # AAPP26473)
Datasheets/Manuals:
Printable datasheet for anti-RNF31 (ARP43241_P050-FITC) antibody
Target Reference:
Kirisako,T., (2006) EMBO J. 25 (20), 4877-4887
Publications:

Queisser, M. A. et al. HOIL-1L Functions as the PKCζ Ubiquitin Ligase to Promote Lung Tumor Growth. (2014). at WB, Human, Rabbit, Rat, Guinea pig, Bovine, Dog, Mouse, Horse 25118570

Sieber, S. et al. Sharpin contributes to TNF-alpha dependent NFκB activation and anti-apoptotic signalling in hepatocytes. PLoS One 7, e29993 (2012). WB, IP, Human, Rabbit, Rat, Guinea pig, Bovine, Dog, Mouse, Horse 22253853

Smit, J. J. et al. The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension. EMBO J. 31, 3833-44 (2012). WB, IP, Human, Rabbit, Rat, Guinea pig, Bovine, Dog, Mouse, Horse 22863777

Blackwell, K. et al. Two coordinated mechanisms underlie tumor necrosis factor alpha-induced immediate and delayed IκB kinase activation. Mol. Cell. Biol. 33, 1901-15 (2013). WB, IP, Human, Rabbit, Rat, Guinea pig, Bovine, Dog, Mouse, Horse 23459942

Liu, S. et al. MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades. Elife 2, e00785 (2013). WB, IP, Human, Rabbit, Rat, Guinea pig, Bovine, Dog, Mouse, Horse 23951545

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