Size:100 ul
$319.00
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ARP43241_P050
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Conjugation Options

ARP43241_P050-FITC Conjugated

ARP43241_P050-HRP Conjugated

ARP43241_P050-Biotin Conjugated

RNF31 Antibody - middle region (ARP43241_P050)

Rating:
100% of 100
Catalog#: ARP43241_P050
Domestic: within 1-2 days delivery | International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-153046 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human RNF31
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 100%
Complete computational species homology data Anti-RNF31 (ARP43241_P050)
Peptide Sequence Synthetic peptide located within the following region: SLINAHSLDPATLYEVEELETATERYLHVRPQPLAGEDPPAYQARLLQKL
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-RNF31 (ARP43241_P050) antibody is Catalog # AAP43241 (Previous Catalog # AAPP26473)
Datasheets/Manuals Printable datasheet for anti-RNF31 (ARP43241_P050) antibody
Target Reference Kirisako,T., (2006) EMBO J. 25 (20), 4877-4887
Publications

Blackwell, K. et al. Two coordinated mechanisms underlie tumor necrosis factor alpha-induced immediate and delayed IκB kinase activation. Mol. Cell. Biol. 33, 1901-15 (2013). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 23459942

Kupka, S; De Miguel, D; Draber, P; Martino, L; Surinova, S; Rittinger, K; Walczak, H; SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes. 16, 2271-80 (2016). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 27545878

Lafont, E; Kantari-Mimoun, C; Draber, P; De Miguel, D; Hartwig, T; Reichert, M; Kupka, S; Shimizu, Y; Taraborrelli, L; Spit, M; Sprick, MR; Walczak, H; The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death. , (2017). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 28258062

Liu, S. et al. MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades. Elife 2, e00785 (2013). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 23951545

Queisser, M. A. et al. HOIL-1L Functions as the PKCz Ubiquitin Ligase to Promote Lung Tumor Growth. (2014). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 25118570

Shibata, Y; Tokunaga, F; Goto, E; Komatsu, G; Gohda, J; Saeki, Y; Tanaka, K; Takahashi, H; Sawasaki, T; Inoue, S; Oshiumi, H; Seya, T; Nakano, H; Tanaka, Y; Iwai, K; Inoue, JI; HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains. 13, e1006162 (2017). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 28103322

Sieber, S. et al. Sharpin contributes to TNF-alpha dependent NFκB activation and anti-apoptotic signalling in hepatocytes. PLoS One 7, e29993 (2012). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 22253853

Smit, J. J. et al. The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension. EMBO J. 31, 3833-44 (2012). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 22863777

Gene Symbol RNF31
Official Gene Full Name Ring finger protein 31
Alias Symbols FLJ10111, FLJ23501, MGC19975, ZIBRA, HOIP
NCBI Gene Id 55072
Protein Name E3 ubiquitin-protein ligase RNF31
Description of Target PWP2 contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions.The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions.
Swissprot Id Q96EP0
Protein Accession # NP_060469
Nucleotide Accession # NM_017999
Protein Size (# AA) 1072
Molecular Weight 120kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express RNF31.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express RNF31.
Protein Interactions CCDC24; VASN; KRTAP9-2; TSSC4; UBC; SNRPC; PRKCA; AES; PITX1; KIF1A; SHARPIN; RBCK1; RNF31; MALT1; VCP; OTULIN; IRAK1; ESR1; Ikbkg; CCDC14; WRNIP1; AKAP8L; TRAF2; TNF; NDUFA8; BIRC2; NOD2; BIRC3; HCVgp1; SOCS3; SMAD3; NOS3; UBE2D3; UBE2D1; TNFAIP3; GFI1B;
  1. What is the species homology for "RNF31 Antibody - middle region (ARP43241_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat".

  2. How long will it take to receive "RNF31 Antibody - middle region (ARP43241_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "RNF31 Antibody - middle region (ARP43241_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "RNF31 Antibody - middle region (ARP43241_P050)"?

    This target may also be called "FLJ10111, FLJ23501, MGC19975, ZIBRA, HOIP" in publications.

  5. What is the shipping cost for "RNF31 Antibody - middle region (ARP43241_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "RNF31 Antibody - middle region (ARP43241_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "RNF31 Antibody - middle region (ARP43241_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "120kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "RNF31 Antibody - middle region (ARP43241_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "RNF31"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "RNF31"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "RNF31"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "RNF31"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "RNF31"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "RNF31"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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