Size:100 ul
$319.00
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SKU
ARP43241_P050
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Conjugation Options

ARP43241_P050-FITC Conjugated

ARP43241_P050-HRP Conjugated

ARP43241_P050-Biotin Conjugated

RNF31 Antibody - middle region (ARP43241_P050)

Rating:
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Catalog#: ARP43241_P050
Domestic: within 1-2 days delivery International: 1-2 days
More Information
Tested Species ReactivityHuman
Predicted Species ReactivityCow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement ItemThis antibody may replace item sc-153046 from Santa Cruz Biotechnology.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human RNF31
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 100%
Complete computational species homology dataAnti-RNF31 (ARP43241_P050)
Peptide SequenceSynthetic peptide located within the following region: SLINAHSLDPATLYEVEELETATERYLHVRPQPLAGEDPPAYQARLLQKL
ConcentrationBatch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking PeptideFor anti-RNF31 (ARP43241_P050) antibody is Catalog # AAP43241 (Previous Catalog # AAPP26473)
Datasheets/ManualsPrintable datasheet for anti-RNF31 (ARP43241_P050) antibody
Target ReferenceKirisako,T., (2006) EMBO J. 25 (20), 4877-4887
Publications

Blackwell, K. et al. Two coordinated mechanisms underlie tumor necrosis factor alpha-induced immediate and delayed IκB kinase activation. Mol. Cell. Biol. 33, 1901-15 (2013). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 23459942

Kupka, S; De Miguel, D; Draber, P; Martino, L; Surinova, S; Rittinger, K; Walczak, H; SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes. 16, 2271-80 (2016). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 27545878

Lafont, E; Kantari-Mimoun, C; Draber, P; De Miguel, D; Hartwig, T; Reichert, M; Kupka, S; Shimizu, Y; Taraborrelli, L; Spit, M; Sprick, MR; Walczak, H; The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death. , (2017). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 28258062

Liu, S. et al. MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades. Elife 2, e00785 (2013). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 23951545

Queisser, M. A. et al. HOIL-1L Functions as the PKCz Ubiquitin Ligase to Promote Lung Tumor Growth. (2014). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 25118570

Shibata, Y; Tokunaga, F; Goto, E; Komatsu, G; Gohda, J; Saeki, Y; Tanaka, K; Takahashi, H; Sawasaki, T; Inoue, S; Oshiumi, H; Seya, T; Nakano, H; Tanaka, Y; Iwai, K; Inoue, JI; HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains. 13, e1006162 (2017). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 28103322

Sieber, S. et al. Sharpin contributes to TNF-alpha dependent NFκB activation and anti-apoptotic signalling in hepatocytes. PLoS One 7, e29993 (2012). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 22253853

Smit, J. J. et al. The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension. EMBO J. 31, 3833-44 (2012). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 22863777

Gene SymbolRNF31
Official Gene Full NameRing finger protein 31
Alias SymbolsFLJ10111, FLJ23501, MGC19975, ZIBRA, HOIP
NCBI Gene Id55072
Protein NameE3 ubiquitin-protein ligase RNF31
Description of TargetPWP2 contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions.The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions.
Swissprot IdQ96EP0
Protein Accession #NP_060469
Nucleotide Accession #NM_017999
Protein Size (# AA)1072
Molecular Weight120kDa
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express RNF31.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express RNF31.
Protein InteractionsCCDC24; VASN; KRTAP9-2; TSSC4; UBC; SNRPC; PRKCA; AES; PITX1; KIF1A; SHARPIN; RBCK1; RNF31; MALT1; VCP; OTULIN; IRAK1; ESR1; Ikbkg; CCDC14; WRNIP1; AKAP8L; TRAF2; TNF; NDUFA8; BIRC2; NOD2; BIRC3; HCVgp1; SOCS3; SMAD3; NOS3; UBE2D3; UBE2D1; TNFAIP3; GFI1B;
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