RAB25 Antibody : FITC (OAEC04272-FITC)

Catalog No: OAEC04272-FITC

Size:100 ug/100 ul

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.
• Clonality: Monoclonal
• Clone: 3F12F3
• Isotype: IgG1
• Host: Mouse
• Conjugation: FITC: Fluorescein Isothiocyanate
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: Purified recombinant fragment of Rab25 expres sed in EColi
• Concentration: 1 mg/ml
• Application Info: WB: 1/500 - 1/2000
  IHC: 1/200 - 1/1000
  ELISA: 1/10000
  

Target Info

• Gene Symbol: RAB25
• Gene Full Name: RAB25, member RAS oncogene family
• Alias Symbols: CATX-8, RAB11C
• NCBI Gene Id: 57111
• Description of Target: Mem bers of the Ras-related superfamily of GTP binding proteins, which includes Ras, Rho, Rab and ARF subfamilies, exhibit 30-50% similarity with Ras p21. Rab proteins play an important role for either in endocytos is or in biosynthetic protein transport. The possibility that Rab proteins might also direct the exocytos is from secretory ves icles to the plasma membrane is supported by the observation that in yeas t, the SEC4 protein, which is 40% similar to Rab proteins, is associated with secretory vesicles. Rab proteins located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fus ion reactions. Rab25 was cloned from a gastric parietal cell cDNA library and is expressed in epithelial tissues such as the gastrointestinal mucosae, kidney, and lung, which encoded a protein of 28 kDa
• Uniprot ID: P57735