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Catalog No: OAAL00257
Size:100UG
Price: $420.00
SKU
OAAL00257
Availability: Domestic: within 2-3 week delivery | International: 2-3 weeks
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Datasheets/ManualsPrintable datasheet for PRKCI Antibody (OAAL00257)
Product Info
Predicted Species ReactivityHuman, Mouse
Product FormatLiquid
ClonalityMonoclonal
Clone1C10
IsotypeIgG1 Kappa
HostMouse
ApplicationEnzyme-linked immunosorbent assay|Western blot
Reconstitution and StorageStore at -20C or lower. Aliquot to avoid repeated freezing and thawing.
ImmunogenPRKCI (AAH22016, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Peptide SequenceMSHTVAGGGSGDHSHQVRVKAYYRGDIMITHFEPSISFEGLCNEVRDMCSFDNEQLFTMKWIDEEGDPCTVSSQLELEEAFRLYELNKDSELLIHVFPCV
FormulationIn 1x PBS, pH 7.4
Gene SymbolPRKCI
Gene Full Nameprotein kinase C iota
Alias SymbolsaPKC-lambda/iota;atypical protein kinase C-lambda/iota;DXS1179E;nPKC-iota;PKCI;PRKC-lambda/iota;protein kinase C iota type.
NCBI Gene Id5584
Protein NameHomo sapiens protein kinase C, iota, mRNA (cDNA clone MGC:26534 IMAGE:4823853), complete cds|Protein kinase C, iota [Homo sapiens]
Description of TargetThis gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X. [provided by RefSeq
Protein Accession #https://www.ncbi.nlm.nih.gov/protein/AAH22016
Nucleotide Accession #https://www.ncbi.nlm.nih.gov/nuccore/BC022016
  1. What is the species homology for "PRKCI Antibody (OAAL00257)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse".

  2. How long will it take to receive "PRKCI Antibody (OAAL00257)"?

    This item is available "Domestic: within 2-3 week delivery | International: 2-3 weeks".

  3. What buffer format is "PRKCI Antibody (OAAL00257)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "PRKCI Antibody (OAAL00257)"?

    This target may also be called "aPKC-lambda/iota;atypical protein kinase C-lambda/iota;DXS1179E;nPKC-iota;PKCI;PRKC-lambda/iota;protein kinase C iota type." in publications.

  5. What is the shipping cost for "PRKCI Antibody (OAAL00257)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "PRKCI Antibody (OAAL00257)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "PRKCI Antibody (OAAL00257)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "PRKCI Antibody (OAAL00257)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "PRKCI"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PRKCI"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PRKCI"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PRKCI"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PRKCI"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PRKCI"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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