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PAX4 Antibody - middle region (OAAB03746)

400ul
$390.00
In Stock
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Predicted Species Reactivity:
Human, Mouse
Product Format:
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Host:
Rabbit
Application:
WB, IHC, FC
Additional Information:
Function: Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters. Competes with PAX6 for this same promoter binding site. Isoform 2 appears to be a dominant negative form antagonizing PAX4 transcriptional activity.
:::
Cellular Location: Nucleus.
Reconstitution and Storage:
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Gene Symbol:
PAX4
NCBI Gene Id:
5078
Protein Name:
Paired box protein Pax-4
Swissprot Id:
O43316
Protein Accession #:
NP_006184.2
Alias Symbols:
Paired box protein Pax-4, PAX4
Replacement Item:
This antibody may replace item sc-27832 from Santa Cruz Biotechnology.
Molecular Weight:
37833 Da
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express PAX4.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express PAX4.
Immunogen:
This PAX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-200 amino acids from the Central region of human PAX4.
Predicted Homology Based on Immunogen Sequence:
Human; Mouse
Concentration:
Approximately 0.5mg/ml. Actual concentration varies with each lot.
Datasheets/Manuals:
Printable datasheet for anti-PAX4 antibody - OAAB03746
Application Info:
WB: 1:2000
WB: 1:1000
IHC-P: 1:10~50
FC: 1:10~50
Other Applications Image 1 Data:
Flow cytometric analysis of widr cells using PAX4 Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram)FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

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