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Now Offering Over 102,157 Antibodies & 44,722 Antigens!

NPM1 antibody - N-terminal region (ARP34094_T100)

100 ul
$249.00
In Stock

Conjugation Options

ARP34094_T100-FITC Conjugated

ARP34094_T100-HRP Conjugated

ARP34094_T100-Biotin Conjugated

Gene Symbol:
NPM1
NCBI Gene Id:
4869
Official Gene Full Name:
Nucleophosmin (nucleolar phosphoprotein B23, numatrin)
Protein Name:
Nucleophosmin
Swissprot Id:
P06748
Protein Accession #:
NP_002511
Nucleotide Accession #:
NM_002520
Alias Symbols:
B23, NPM
Replacement Item:
This antibody may replace item sc-116348 from Santa Cruz Biotechnology.
Description of Target:
NPM1 is a member of Nucleophosmin (NPM) family. NPM is a ubiquitously expressed nucleolar phosphoprotein that continuously shuttles between the nucleus and cytoplasm
Protein Size (# AA):
294
Molecular Weight:
33kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Protein A purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express NPM1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express NPM1.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human NPM1
Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Predicted Homology Based on Immunogen Sequence:
Cow: 93%; Dog: 100%; Guinea Pig: 77%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
Complete computational species homology data:
Anti-NPM1 (ARP34094_T100)
Peptide Sequence:
Synthetic peptide located within the following region: DMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKD
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
COX8A; NPM2; HUWE1; UBC; PA2G4; FUS; TP53; AURKA; SUMO2; SUMO3; ELF4; STAU1; CDKN2A; LGR4; SUMO1; MDM2; RPA3; RPA2; RPA1; ERG; rev; TRMT61A; OSBP; KPNA1; LIMCH1; ARMCX3; YWHAQ; PARK2; TARDBP; TUBA1C; TAB2; CEP152; DZIP1; COPG1; STK38; COPE; PARK7; AKAP11;
Blocking Peptide:
For anti-NPM1 (ARP34094_T100) antibody is Catalog # AAP34094 (Previous Catalog # AAPP05303)
Datasheets/Manuals:
Printable datasheet for anti-NPM1 (ARP34094_T100) antibody
Sample Type Confirmation:

There is BioGPS gene expression data showing that NPM1 is expressed in HepG2

Target Reference:
Falini,B., et al., (2005) N. Engl. J. Med. 352 (3), 254-266
Publications:

Komorek, J. et al. Adenovirus type 5 E1A and E6 proteins of low-risk cutaneous beta-human papillomaviruses suppress cell transformation through interaction with FOXK1/K2 transcription factors. J. Virol. 84, 2719-31 (2010). IHC, WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat 20053746

Lin, S., Coutinho-Mansfield, G., Wang, D., Pandit, S. & Fu, X.-D. The splicing factor SC35 has an active role in transcriptional elongation. Nat. Struct. Mol. Biol. 15, 819-26 (2008). IHC, WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat 18641664

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