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Catalog No: OPCD00819
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OPCD00819
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Datasheets/ManualsPrintable datasheet for MFN1 Recombinant Protein (OPCD00819)
Product Info
Predicted Species ReactivityMouse|Mus musculus
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Met1-Ile234
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolMfn1
Gene Full Namemitofusin 1
Alias Symbols2310002F04Rik;6330416C07Rik;D3Ertd265;D3Ertd265e;HR;HR2;mitofusin-1;mKIAA4032;transmembrane GTPase MFN1.
NCBI Gene Id67414
Protein NameMitofusin-1
Description of TargetMitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed:12527753, PubMed:23921378, PubMed:24513856, PubMed:15297672). Membrane clustering requires GTPase activity (By similarity). It may involve a major rearrangement of the coiled coil domains (PubMed:15297672). Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events (PubMed:12527753). Overexpression induces the formation of mitochondrial networks (in vitro). Has low GTPase activity (By similarity).
Uniprot IDQ811U4
Protein Accession #NP_077162.2
Nucleotide Accession #NM_024200.4
Protein Size (# AA)Met1~Ile234
Molecular Weight30kDa
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