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MED25 Antibody - N-terminal region (OAAB00209)

400ul
$320.00
In Stock
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Gene Symbol:
MED25
NCBI Gene Id:
81857
Protein Name:
Mediator of RNA polymerase II transcription subunit 25
Swissprot Id:
Q71SY5
Protein Accession #:
NP_112235.2
Alias Symbols:
Mediator of RNA polymerase II transcription subunit 25,MED25,ACID1, ARC92, PTOV2
Replacement Item:
This antibody may replace item sc-149352 from Santa Cruz Biotechnology.
Description of Target:
This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2.
Molecular Weight:
78171 Da
Host:
Rabbit
Clonality:
Polyclonal
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Application:
WB, IHC-P
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express MED25.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express MED25.
Immunogen:
This MED25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-140 amino acids from the N-terminal region of human MED25.
Predicted Homology Based on Immunogen Sequence:
Cow; Human; Mouse
Product Format:
Liquid. PBS with 0.09% (W/V) sodium azide.
Reconstitution and Storage:
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Approximately 0.5mg/ml. Actual concentration varies with each lot.
Datasheets/Manuals:
Printable datasheet for anti-MED25 antibody - OAAB00209
Isotype:
Ig
Intended Use:
For research use only and not for use in diagnostic or therapeutic procedures.
Application Info:
WB 1:1000
IHC-P 1:50~100
:::
Cellular Location: Nucleus
Tissue Location: Ubiquitously expressed. Highest levels in brain, heart, kidney, peripheral leukocytes, placenta, skeletal muscle and spleen.
Publications:

Lee, B; Wu, CY; Lin, YW; Park, SW; Wei, LN; Synergistic activation of Arg1 gene by retinoic acid and IL-4 involves chromatin remodeling for transcription initiation and elongation coupling. 44, 7568-79 (2016). WB, IHC-P, Human, Mouse 27166374

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