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MED25 Antibody - N-terminal region (OAAB00209)

Catalog#: OAAB00209
Domestic: within 1 week delivery | International: 1 week
More Information
Predicted Species ReactivityHuman, Mouse, Bovine
Product FormatLiquid. PBS with 0.09% (W/V) sodium azide.
ApplicationWB, IHC-P
Additional InformationCellular Location: Nucleus
Tissue Location: Ubiquitously expressed. Highest levels in brain, heart, kidney, peripheral leukocytes, placenta, skeletal muscle and spleen.
Reconstitution and StorageMaintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement ItemThis antibody may replace item sc-149352 from Santa Cruz Biotechnology.
ImmunogenThis MED25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-140 amino acids of human MED25.
PurificationThis antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration0.39 mg/mL
Datasheets/ManualsPrintable datasheet for anti-MED25 antibody - OAAB00209
Intended UseFor research use only and not for use in diagnostic or therapeutic procedures.
Application InfoWB: 1:1000
IHC-P: 1:50~100

Lee, B; Wu, CY; Lin, YW; Park, SW; Wei, LN; Synergistic activation of Arg1 gene by retinoic acid and IL-4 involves chromatin remodeling for transcription initiation and elongation coupling. 44, 7568-79 (2016). WB, IHC-P, Human, Mouse 27166374

Gene SymbolMED25
Alias SymbolsMediator of RNA polymerase II transcription subunit 25, Activator interaction domain-containing protein 1, Activator-recruited cofactor 92 kDa component, ARC92, Mediator complex subunit 25, p78, MED25, ACID1, ARC92, PTOV2
NCBI Gene Id81857
Protein NameMediator of RNA polymerase II transcription subunit 25
Description of TargetThis gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2.
Swissprot IdQ71SY5
Protein Accession #NP_112235.2
Molecular Weight78 kDa
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express MED25.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express MED25.
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