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MED25 Antibody - N-terminal region (OAAB00209)

400ul
$390.00
In Stock
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Predicted Species Reactivity:
Human, Mouse, Bovine
Product Format:
Liquid. PBS with 0.09% (W/V) sodium azide.
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
ELISA, WB, IHC-P
Additional Information:
Cellular Location: Nucleus
Tissue Location: Ubiquitously expressed. Highest levels in brain, heart, kidney, peripheral leukocytes, placenta, skeletal muscle and spleen.
Reconstitution and Storage:
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Gene Symbol:
MED25
NCBI Gene Id:
81857
Protein Name:
Mediator of RNA polymerase II transcription subunit 25
Swissprot Id:
Q71SY5
Protein Accession #:
NP_112235.2
Alias Symbols:
Mediator of RNA polymerase II transcription subunit 25, Activator interaction domain-containing protein 1, Activator-recruited cofactor 92 kDa component, ARC92, Mediator complex subunit 25, p78, MED25, ACID1, ARC92, PTOV2
Replacement Item:
This antibody may replace item sc-149352 from Santa Cruz Biotechnology.
Description of Target:
This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2.
Molecular Weight:
78 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express MED25.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express MED25.
Immunogen:
This MED25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-140 amino acids of human MED25.
Concentration:
0.39 mg/mL
Datasheets/Manuals:
Printable datasheet for anti-MED25 antibody - OAAB00209
Intended Use:
For research use only and not for use in diagnostic or therapeutic procedures.
Application Info:
WB: 1:1000
IHC-P: 1:50~100
Publications:

Lee, B; Wu, CY; Lin, YW; Park, SW; Wei, LN; Synergistic activation of Arg1 gene by retinoic acid and IL-4 involves chromatin remodeling for transcription initiation and elongation coupling. 44, 7568-79 (2016). WB, IHC-P, Human, Mouse 27166374

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