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MAPT Antibody (Phospho-Ser396) : Biotin (OABF01246-Biotin)

100 ul
$389.00
In Stock
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Conjugation Options

OABF01246 Unconjugated

OABF01246-FITC Conjugated

OABF01246-HRP Conjugated

Gene Symbol:
MAPT
Official Gene Full Name:
microtubule-associated protein tau
NCBI Gene Id:
4137
Swissprot Id:
P10636
Alias Symbols:
TAU, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, FTDP-17, PPP1R103,
Replacement Item:
This antibody may replace item sc-166062 from Santa Cruz Biotechnology.
Description of Target:
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Purified by Protein A.
Application:
WB, IHC-P, IF
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express MAPT.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express MAPT.
Immunogen:
KLH conjugated synthetic phosphopeptide derived from human Tau protein around the phosphorylation site of Ser396 [KT(p-S)T]
Predicted Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution and Storage:
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for OABF01246-Biotin
Conjugation:
Biotin
Isotype:
IgG
Application Info:
WB(1:100-1000)
IHC-P(1:100-500)
IF(1:50-200)
Additional Information:
Subcellular location: Cytoplasm
:::
Modification: Phosphorylation (Ser396)

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