Size:100 ul
$469.00
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SKU
OABF01246-Biotin
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Conjugation Options

OABF01246 Unconjugated

OABF01246-FITC Conjugated

OABF01246-HRP Conjugated

MAPT Antibody (Phospho-Ser396) : Biotin (OABF01246-Biotin)

Catalog#: OABF01246-Biotin
Domestic: within 1 week delivery | International: 1 week
More Information
Predicted Species ReactivityHuman, Mouse, Rat
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer.
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ConjugationBiotin
ApplicationWB, IHC-P, IF
Additional InformationSubcellular location: Cytoplasm
::Modification: Phosphorylation (Ser396)
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Replacement ItemThis antibody may replace item sc-166062 from Santa Cruz Biotechnology.
ImmunogenKLH conjugated synthetic phosphopeptide derived from human Tau protein around the phosphorylation site of Ser396 [KT(p-S)T]
PurificationPurified by Protein A.
Concentration1 mg/ml
Datasheets/ManualsPrintable datasheet for OABF01246-Biotin
Application InfoWB(1:100-1000)
IHC-P(1:100-500)
IF(1:50-200)
Gene SymbolMAPT
Official Gene Full Namemicrotubule-associated protein tau
Alias SymbolsTAU, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, FTDP-17, PPP1R103,
NCBI Gene Id4137
Description of TargetPromotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Swissprot IdP10636
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express MAPT.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express MAPT.
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