Size:100 ul
Special Price $229.00 Regular Price $289.00
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SKU
ARP48103_P050
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Conjugation Options

ARP48103_P050-FITC Conjugated

ARP48103_P050-HRP Conjugated

ARP48103_P050-Biotin Conjugated

More Information
Tested Species ReactivityHuman, Mouse
Predicted Species ReactivityHuman, Mouse, Pig, Rat
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationIHC, WB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement ItemThis antibody may replace item sc-166062 from Santa Cruz Biotechnology.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human MAPT
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceHuman: 100%; Mouse: 86%; Pig: 79%; Rat: 86%
Complete computational species homology dataAnti-MAPT (ARP48103_P050)
Peptide SequenceSynthetic peptide located within the following region: RGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPG
ConcentrationBatch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking PeptideFor anti-MAPT (ARP48103_P050) antibody is Catalog # AAP48103 (Previous Catalog # AAPS21802)
Datasheets/ManualsPrintable datasheet for anti-MAPT (ARP48103_P050) antibody
Target ReferenceReynolds,M.R., (2006) Biochemistry 45 (13), 4314-4326
Gene SymbolMAPT
Official Gene Full NameMicrotubule-associated protein tau
Alias SymbolsDDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, TAU
NCBI Gene Id4137
Protein NameMicrotubule-associated protein tau
Description of TargetMAPT is differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. The mutations in the gene have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Swissprot IdP10636-8
Protein Accession #NP_005901
Nucleotide Accession #NM_005910
Protein Size (# AA)441
Molecular Weight46kDa
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express MAPT.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express MAPT.
Protein InteractionsYwhaz; Prkaca; STUB1; PHGK; SRC; PRKAR1A; GSK3B; FYN; DCTN1; CSNK1A1; CDK2; AKT1; ABL1; YWHAQ; SGK1; MARK2; MARCH7; TUBB3; TUBA1B; UBC; TUBA4A; MARK4; PEG10; MARK3; MARK1; MAPK13; MAPK11; MAPK8; mapk14; Mapk12; LIMS1; HSPA1A; PPP5C; PPP2R4; CAPN2; PKN1; H
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