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MAPT Antibody (Phospho-Ser396) (OABF01246)

100 ul
$389.00
In Stock
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Conjugation Options

OABF01246-FITC Conjugated

OABF01246-HRP Conjugated

OABF01246-Biotin Conjugated

Gene Symbol:
MAPT
Official Gene Full Name:
microtubule-associated protein tau
NCBI Gene Id:
4137
Swissprot Id:
P10636
Alias Symbols:
TAU, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, FTDP-17, PPP1R103,
Replacement Item:
This antibody may replace item sc-166062 from Santa Cruz Biotechnology.
Description of Target:
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Purified by Protein A.
Application:
WB, IHC-P
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express MAPT.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express MAPT.
Immunogen:
KLH conjugated synthetic phosphopeptide derived from human Tau protein around the phosphorylation site of Ser396 [KT(p-S)T]
Predicted Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.
Reconstitution and Storage:
Store at -20C for 12 months.
Concentration:
1ug/ul
Datasheets/Manuals:
Printable datasheet for OABF01246
Conjugation:
Unconjugated
Isotype:
IgG
Application Info:
WB: 1:100 - 1000
IHC-P: : 1:100 - 500
Additional Information:
Subcellular location: Cytoplasm
:::
Modification: Phosphorylation (Ser396)

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