MAPT Antibody (Phospho-Ser396) (OABF01246)

Catalog No: OABF01246

Size:100UL

Formalin-fixed and paraffin embedded rat brain labeled with Anti-phospho-Tau protein (Ser396) Polyclonal Antibody, Unconjugated (OABF01246) at 1:200 followed by conjugation to the secondary antibody

Formalin-fixed and paraffin embedded mouse brain labeled with Anti-phospho-Tau protein (Ser396) Polyclonal Antibody, Unconjugated (OABF01246) at 1:200 followed by conjugation to the secondary antibody Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37C and DAPI staining

Formalin-fixed and paraffin embedded Human endometrium labeled with Anti-phospho-Tau protein (Ser396) Polyclonal Antibody, Unconjugated (OABF01246) at 1:200 followed by conjugation to the secondary antibody Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37C and DAPI staining

Product Info

• Predicted Species Reactivity: Dog|Human|Mouse|Rat
• Product Format: Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Western blot
• Additional Information: Subcellular location: Cytoplasm
  Modification: Phosphorylation (Ser396)
• Reconstitution and Storage: -20°C
• Immunogen: KLH conjugated synthetic phosphopeptide derived from human Tau protein around the phosphorylation site of Ser396 [KT(p-S)T]
• Purification: Protein A Purified
• Concentration: 1 ug/ul
• Application Info: WB: 1:100 - 1000
  IHC-P: : 1:100 - 500

Target Info

• Gene Symbol: MAPT
• Gene Full Name: microtubule associated protein tau
• Alias Symbols: DDPAC;FTDP-17;G protein beta1/gamma2 subunit-interacting factor 1;MAPTL;microtubule-associated protein tau;MSTD;MTBT1;MTBT2;neurofibrillary tangle protein;paired helical filament-tau;PHF-tau;PPND;PPP1R103;protein phosphatase 1, regulatory subunit 103;TAU;tau-40.
• NCBI Gene Id: 4137
• Protein Name: Microtubule-associated protein tau
• Description of Target: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
• Uniprot ID: P10636