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MAPK14 Antibody (Phospho-Thr180/Tyr182) (OAAJ02784)

100 ul
$289.00
In Stock
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Gene Symbol:
MAPK14
Official Gene Full Name:
mitogen-activated protein kinase 14
NCBI Gene Id:
1432
Swissprot Id:
Q16539
Alias Symbols:
Mitogen-activated protein kinase 14; Csaids binding protein; CSBP 1; CSBP 2; CSBP; CSBP1; CSBP2; CSPB1; Cytokine suppressive anti-inflammatory drug-binding protein; EXIP; MAP kinase 14; MAP kinase MXI2; MAP kinase p38 alpha
Replacement Item:
This antibody may replace item sc-114258 from Santa Cruz Biotechnology.
Description of Target:
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines.
Molecular Weight:
43 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Application:
WB, IHC, IF
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express MAPK14.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express MAPK14.
Immunogen:
A synthesized peptide derived from human p38 MAPK around the phosphorylation site of Thr180/Tyr182) .
Predicted Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid. PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Reconstitution and Storage:
Store at -20C. Stable for 12 months from date of receipt.
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-MAPK14 (OAAJ02784) antibody
Specificity:
Phospho-p38 MAPK (Thr180/Tyr182) Antibody detects endogenous levels of p38 MAPK only when phosphorylated at Thr180 and Tyr182
Isotype:
Rabbit IgG
Application Info:
WB: 1:500-1:2000; (For western blot, incubate membrane with diluted primary Ab in 5% w/v milk , 1X TBS, 0.1% Tween®20 at 4C with gentle shaking, overnight.)
IHC: 1:50-1:200
IF: 1:200
Optimal dilutions should be determined by the end user.
Additional Information:
Subcellular Location:Cytoplasm. Nucleus
Tissue Specificity: Brain, heart, placenta, pancreas and skeletal muscle. Expressed to a lesser extent in lung, liver and kidney.
Similarity The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

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