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- $55: Antibody & Protein in US
- $55 + $25/Kit in US
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Datasheets/Manuals | Printable datasheet for anti-MAPK14 (OAED00105) antibody |
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Predicted Species Reactivity | Human, Mouse, Rat, Bovine, Dog, Chicken, Guinea Pig, Hamster, Monkey, Pig, Rabbit, Sheep |
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Clonality | Polyclonal |
Host | Rabbit |
Application | IHC, IP, WB |
Reconstitution and Storage | Long Term Storage : -20C |
Immunogen | Synthetic peptide corresponding to a portion of human p38. The sequence is completely conserved in mouse. |
Specificity | Recognizes human, mouse, rat, bovine, dog, chicken, guinea pig, hamster, monkey, pig, rabbit and sheep p38. Detects a band of ~38kDa by Western blot. |
Formulation | Liquid. Whole rabbit serum. |
Application Info | Immunohistochemistry (paraffin sections) Immunoprecipitation (1:500) Western Blot (1:10,000, ECL) Optimal conditions must be determined individually for each application. |
Gene Symbol | MAPK14 |
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Gene Full Name | Mitogen-activated protein kinase 14 |
Alias Symbols | RK, p38, CSBP, EXIP, Mxi2, CSBP1, CSBP2, CSPB1, PRKM14, PRKM15, SAPK2A, p38ALPHA |
NCBI Gene Id | 1432 |
Protein Name | Mitogen-activated protein kinase 14 |
Description of Target | Six proteins of the p38 subfamily of MAP kinases have been identified to date, including: p38alpha (SAPK2, CSBP) and its splice variant Mxi; p38beta and beta2; p38gamma (ERK6, SAPK3); and p38delta (SAPK4). p38 MAP kinases contain a conserved TGY motif in their activation loop and are activated in response to cytokines, hormones, GPCRs, and osmotic and heat shock to mediate primarily pro-apoptotic and pro-inflammatory responses. MKK3, MKK4, and MKK6 are known to activate p38 family members with varying specificity. All four p38 isoforms are able to phosphorylate the activating transcription factor 2 (ATF2), and differentially activate numerous substrates including Mnk1/2, Msk, phospholipase A2, and the MAPKAP kinase-2 and -3. Activated MAPKAP kinase-2 subsequently phosphorylates the heat shock protein Hsp27, an F-actin binding protein involved in cytoskeletal maintenance. |
Uniprot ID | Q16539 |
Protein Accession # | NP_001306.1; NP_620581.1; NP_620582.1; NP_620583.1 |
Nucleotide Accession # | NM_001315.2; NM_139012.2; NM_139013.2; NM_139014.2 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "MAPK14 Antibody (OAED00105)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Bovine, Dog, Chicken, Guinea Pig, Hamster, Monkey, Pig, Rabbit, Sheep".
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How long will it take to receive "MAPK14 Antibody (OAED00105)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 week".
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What buffer format is "MAPK14 Antibody (OAED00105)" provided in?
This item is provided in "".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "MAPK14 Antibody (OAED00105)"?
This target may also be called "RK, p38, CSBP, EXIP, Mxi2, CSBP1, CSBP2, CSPB1, PRKM14, PRKM15, SAPK2A, p38ALPHA" in publications.
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What is the shipping cost for "MAPK14 Antibody (OAED00105)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "MAPK14 Antibody (OAED00105)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "MAPK14 Antibody (OAED00105)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "MAPK14 Antibody (OAED00105)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "MAPK14"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "MAPK14"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "MAPK14"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "MAPK14"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "MAPK14"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "MAPK14"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.