Product Number |
OAAJ02784 |
Product Page |
www.avivasysbio.com/mapk14-antibody-phospho-thr180-tyr182-oaaj02784.html |
Name |
MAPK14 Antibody (Phospho-Thr180/Tyr182) (OAAJ02784) |
Molecular Weight |
43 kDa |
Isotype |
Rabbit IgG |
NCBI Gene Id |
1432 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1 mg/ml |
Gene Full Name |
mitogen-activated protein kinase 14 |
Alias Symbols |
RK, p38, CSBP, EXIP, Mxi2, CSBP1, CSBP2, CSPB1, PRKM14, PRKM15, SAPK2A, p38ALPHA |
Product Format |
Liquid. PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Description of Target |
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. |
Reconstitution and Storage |
Store at -20C. Stable for 12 months from date of receipt. |
Datasheets/Manuals |
Printable datasheet for anti-MAPK14 (OAAJ02784) antibody |
Specificity |
Phospho-p38 MAPK (Thr180/Tyr182) Antibody detects endogenous levels of p38 MAPK only when phosphorylated at Thr180 and Tyr182 |
Additional Information |
Subcellular Location:Cytoplasm. Nucleus
Tissue Specificity: Brain, heart, placenta, pancreas and skeletal muscle. Expressed to a lesser extent in lung, liver and kidney.
Similarity The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
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Application Info |
WB: 1:500-1:2000; (For western blot, incubate membrane with diluted primary Ab in 5% w/v milk , 1X TBS, 0.1% Tween®20 at 4C with gentle shaking, overnight.) IHC: 1:50-1:200 IF: 1:200 Optimal dilutions should be determined by the end user. |
Immunogen |
A synthesized peptide derived from human p38 MAPK around the phosphorylation site of Thr180/Tyr182) . |
Uniprot ID |
Q16539 |
Purification |
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns. |
Gene Symbol |
MAPK14 |
Predicted Species Reactivity |
Human, Mouse, Rat |
Application |
WB, IHC, IF |
Image 1 | Jurkat whole cell lysates.
| Western blot analysis of p38 MAPK phosphorylation expression in Jurkat whole cell lysates. |
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