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Datasheets/Manuals | Printable datasheet for anti-HIV-1 p24 antibody - OAPA00053 |
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Predicted Species Reactivity | Human Immunodeficiency Virus Type 1 |
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Product Format | Lyophilized. Sterile filtered white powder |
Clonality | Monoclonal |
Clone | YDHIV1gp24 |
Isotype | Mouse IgG1 |
Host | Mouse |
Reconstitution and Storage | Antibody is shipped lyophilized at ambient temperature. Reconstitute with H2O. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |
Immunogen | r.HIV-1p24 |
Purification | Ion exchange column |
Concentration | 1 mg/ml in PBS (after reconstitution) |
Application Info | By direct ELISA (against recombinant gp24), 1:10,000 dilution will yield 0.4 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories). |
Gene Symbol | HIV-1 p24 |
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Alias Symbols | HIV-1 p24 antibody, HIV-1 p24 Mouse antibody |
Protein Name | Gag-Pol polyprotein |
Description of Target | Human immunodeficiency virus (HIV) is a retrovirusthat can lead to a condition in which the immune systembegins to fail, leading to opportunistic infections. HIV primarily infects vital cells in the humanimmune systemsuch as helper T cells(specifically CD4+ T cells), macrophagesand dendritic cells. HIV infection leads to low levels of CD4+ T cells through three main mechanisms: firstly, direct viral killing of infected cells; secondly, increased rates of apoptosisin infected cells; and thirdly, killing of infected CD4+ T cells by CD8 cytotoxic lymphocytesthat recognize infected cells. When CD4+ T cell numbers decline below a critical level, cell-mediated immunityis lost, and the body becomes progressively more susceptible to opportunistic infections. HIV was classified as a member of the genus Lentivirus, part of the family of Retroviridae. Lentiviruses have many common morphologies and biological properties. Many species are infected by lentiviruses, which are characteristically responsible for long-duration illnesses with a long incubation period. Lentiviruses are transmitted as single-stranded, positive-sense, enveloped RNA viruses. Upon entry of the target cell, the viral RNA genomeis converted to double-stranded DNAby a virally encoded reverse transcriptasethat is present in the virus particle. This viral DNA is then integrated into the cellular DNA by a virally encoded integraseso that the genome can be transcribed. Once the virus has infected the cell, two pathways are possible: either the virus becomes latentand the infected cell continues to function, or the virus becomes active and replicates, and a large number of virus particles are liberated that can then infect other cells. |
Uniprot ID | P04585 |
Protein Accession # | NP_057849.4 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "HIV-1 p24 Antibody (OAPA00053)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human Immunodeficiency Virus Type 1".
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How long will it take to receive "HIV-1 p24 Antibody (OAPA00053)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "HIV-1 p24 Antibody (OAPA00053)" provided in?
This item is provided in "Lyophilized. Sterile filtered white powder".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "HIV-1 p24 Antibody (OAPA00053)"?
This target may also be called "HIV-1 p24 antibody, HIV-1 p24 Mouse antibody" in publications.
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What is the shipping cost for "HIV-1 p24 Antibody (OAPA00053)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "HIV-1 p24 Antibody (OAPA00053)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "HIV-1 p24 Antibody (OAPA00053)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "HIV-1 p24 Antibody (OAPA00053)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "HIV-1 P24"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "HIV-1 P24"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "HIV-1 P24"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "HIV-1 P24"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "HIV-1 P24"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "HIV-1 P24"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.