GZMB Recombinant Protein (Human) (OPED00049)

Catalog No: OPED00049

Size:5000U

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Liquid. In 50mM TRIS, pH 7.4, 100mM NaCl, 10% glycerol.
• Host: Yeast
• Additional Information: Granzyme B is a component of the cytolytic granules of cytotoxic T lymphocytes and natural killer cells.
• Reconstitution and Storage: Store at -80C
• Purification: Partially purified by single-step affinity chromatography and gel filtration.

Target Info

• Gene Symbol: GZMB
• Gene Full Name: granzyme B
• Alias Symbols: C11;cathepsin G-like 1;CCPI;CGL1;CGL-1;CSPB;CSP-B;CTLA1;CTLA-1;CTSGL1;cytotoxic serine protease B;cytotoxic T-lymphocyte proteinase 2;fragmentin 2;Fragmentin-2;granzyme B;granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1);Granzyme-2;HLP;human lymphocyte protein;SECT;T-cell serine protease 1-3E.
• NCBI Gene Id: 3002
• Protein Name: Granzyme B
• Description of Target: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
• Uniprot ID: P10144
• Protein Accession #: NP_002418.1
• Nucleotide Accession #: NM_002427.3
• Protein Size (# AA): Recombinant
• Molecular Weight: 25 kDa