ENPP1 Recombinant Protein (OPCD02927)

Catalog No: OPCD02927

ENPP1 Recombinant Protein (OPCD02927) using SDS-PAGE

ENPP1 Recombinant Protein (OPCD02927) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Gly568-Asp789
  Isoelectric Point: 6.3
  Subcellular Location: Membrane, Secreted.
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His and GST Tag

Target Info

• Gene Symbol: Enpp1
• Gene Full Name: ectonucleotide pyrophosphatase/phosphodiesterase 1
• Alias Symbols: 4833416E15Rik;AI428932;C76301;CD203c;ectonucleotide pyrophosphatase/phosphodiesterase family member 1;E-N;E-NPP 1;E-NPP1;Ly-4;Ly-41;lymphocyte antigen 41;M6S1;N;NPP1;Npps;P;PC-;PC-1;Pca;Pca-1;Pd;Pdnp1;phosphodiesterase I/nucleotide pyrophosphatase 1;plasma-cell membrane glycoprotein PC-1;tiptoe walking;ttw;twy.
• NCBI Gene Id: 18605
• Protein Name: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
• Description of Target: Appears to modulate insulin sensitivity (By similarity). By generating PPi, plays a role in regulating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. PPi inhibits mineralization by binding to nascent hydroxyapatite (HA) crystals, thereby preventing further growth of these crystals. Preferentially hydrolyzes ATP, but can also hydrolyze other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3',5'-cAMP to AMP. May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling.
• Uniprot ID: P06802
• Protein Accession #: NP_001295256.1
• Nucleotide Accession #: NM_001308327.1
• Protein Size (# AA): Gly568~Asp789
• Molecular Weight: 56kDa