Mouse Enpp1 Antibody - N-terminal region (OAAB15252)

Catalog No: OAAB15252

Size:400ul

Mouse Enpp1 Antibody (N-term) (Cat. # OAAB15252) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the Mouse Enpp1 antibody detected the Mouse Enpp1 protein (arrow).

Product Info

• Predicted Species Reactivity: Mouse
• Product Format: LiquidPBS with 0.09% (W/V) sodium azide.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB, ELISA
• Additional Information: Cellular Location: Membrane; Single-pass type II membrane protein. Basolateral cell membrane; Single-pass type II membrane protein. Note=Targeted to the basolateral membrane in polarized epithelial cells and in hepatocytes, and to matrix vesicles in osteoblasts. In bile duct cells and cancer cells, located to the apical cytoplasmic side
  Tissue Location: Selectively expressed on the surface of antibody-secreting cells
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This Mouse Enpp1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of mouse Enpp1.
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Concentration: 0.4 mg/ml
• Application Info: WB: 1:1000

Target Info

• Gene Symbol: ENPP1
• Alias Symbols: Enpp1, Npps, Pc1, Pdnp1, Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, Lymphocyte antigen 41, Phosphodiesterase I/nucleotide pyrophosphatase 1, Plasma-cell membrane glycoprotein PC-1, Alkaline phosphodiesterase I, Nucleotide p
• Protein Name: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
• Description of Target: Involved primarily in ATP hydrolysis at the plasma membrane. Plays a role in regulating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. In vitro, has a broad specificity, hydrolyzing other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3',5'-cAMP to AMP. May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. Appears to modulate insulin sensitivity
• Uniprot ID: P06802
• Molecular Weight: 103 kDa