CD14 Antibody (OAAB21739)

Catalog No: OAAB21739

Size:100ul

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. 0.01M TBS (pH 7.4) with 1% BSA, 0.09% (w/v) sodium azide and 50% Glycerol.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB, FC, IHC-P
  Cellular Location: Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Membrane raft. Golgi apparatus. Note=Soluble, secreted forms seem to exist. They may arise by cleavage of the GPI anchor.
  Tissue Location: Detected on peritoneal macrophages (at protein level). Cell surface expression detected in lung alveolar macrophages, dendritic macrophages and lung macrophages (at protein level).
• Reconstitution and Storage: Store at -20°C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least two weeks at 2-4°C.
• Concentration: 1 mg/ml
• Application Info: WB: 1:100~1:500
  IHC-P: 1:100~1:500
  FC: 1:20~1:100

Target Info

• Gene Symbol: CD14
• Gene Full Name: CD14 antigen
• Alias Symbols: Monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; CD14
• NCBI Gene Id: 12475
• Description of Target: In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
• Uniprot ID: P10810
• Protein Accession #: NP_033971.1
• Nucleotide Accession #: NM_009841.4
• Molecular Weight: 39 kDa