TFAM Recombinant Protein (OPCD07332)

Catalog No: OPCD07332

TFAM Recombinant Protein (OPCD07332) using SDS-PAGE

TFAM Recombinant Protein (OPCD07332) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ser43-Cys246
  Isoelectric Point: 9.1
  Subcellular Location: Mitochondrion
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 50 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: TFAM
• Gene Full Name: transcription factor A, mitochondrial
• Alias Symbols: mitochondrial transcription factor 1;mitochondrial transcription factor A;MTDPS15;MTTF1;MTTFA;TCF6;TCF6L1;TCF6L2;TCF6L3;transcription factor 6;transcription factor 6-like 1;Transcription factor 6-like 2;transcription factor 6-like 2 (mitochondrial transcription factor);transcription factor 6-like 3;transcription factor A, mitochondrial.
• NCBI Gene Id: 7019
• Protein Name: Transcription factor A, mitochondrial
• Description of Target: Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation (PubMed:29445193). Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA.
• Uniprot ID: Q00059
• Protein Accession #: NP_001257711.1
• Nucleotide Accession #: NM_001270782.1
• Protein Size (# AA): Ser43~Cys246
• Molecular Weight: 30kDa