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Catalog No: OAAB17784
Size:400ul
Price: $463.00
SKU
OAAB17784
Availability: Domestic: within 1-2 week delivery | International: within 1-2 week delivery
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for OAAB17784
Product Info
Predicted Species ReactivityMouse, Rat, Pig
Product FormatLiquid. Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
ClonalityMonoclonal
IsotypeIgG2a, kappa
HostMouse
ApplicationWB
Reconstitution and StorageMaintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThis STAT3 antibody is generated from a mouse immunized with a recombinant protein from human.
PurificationThis antibody is purified through a protein G column, followed by dialysis against PBS.
Predicted Homology Based on Immunogen SequenceMouse; Pig; Rat
Application InfoWB: 1:1000
ReferenceAkira S., et al.Cell 77:63-71(1994).
Della Pietra L., et al.Gene 213:119-124(1998).
Ota T., et al.Nat. Genet. 36:40-45(2004).
Della Pietra L., et al.Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases.
Zhang X., et al.Science 267:1990-1994(1995).
Gene SymbolSTAT3
Alias SymbolsAPRF, HIES, ADMIO, ADMIO1
NCBI Gene Id6774
Description of TargetSignal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).
Uniprot IDP40763, P52631, Q19S50, P42227
Molecular Weight88 kDa
  1. What is the species homology for "STAT3 Antibody (OAAB17784)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Mouse, Rat, Pig".

  2. How long will it take to receive "STAT3 Antibody (OAAB17784)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "STAT3 Antibody (OAAB17784)" provided in?

    This item is provided in "Liquid. Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "STAT3 Antibody (OAAB17784)"?

    This target may also be called "APRF, HIES, ADMIO, ADMIO1" in publications.

  5. What is the shipping cost for "STAT3 Antibody (OAAB17784)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "STAT3 Antibody (OAAB17784)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "STAT3 Antibody (OAAB17784)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "88 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "STAT3 Antibody (OAAB17784)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "STAT3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "STAT3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "STAT3"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "STAT3"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "STAT3"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "STAT3"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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