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RARB Antibody - middle region (OAAB13645)

400ul
$390.00
In Stock
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Gene Symbol:
RARB
NCBI Gene Id:
5915
Protein Name:
Retinoic acid receptor beta
Swissprot Id:
P10826
Protein Accession #:
NP_000956.2
Alias Symbols:
RARB, HAP, NR1B2, Retinoic acid receptor beta, HBV-activated protein, Nuclear receptor subfamily 1 group B member 2, RAR-epsilon
Replacement Item:
This antibody may replace item sc-29466 from Santa Cruz Biotechnology.
Description of Target:
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Molecular Weight:
50489 Da
Host:
Rabbit
Clonality:
Polyclonal
Application:
IF, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express RARB.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express RARB.
Immunogen:
This RARB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-195 amino acids from the Central region of human RARB.
Predicted Species Reactivity:
Human, Mouse
Predicted Homology Based on Immunogen Sequence:
Human; Mouse
Product Format:
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Reconstitution and Storage:
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Approximately 0.5mg/ml. Actual concentration varies with each lot.
Datasheets/Manuals:
Printable datasheet for OAAB13645
Sample Type Confirmation:

RARB is supported by BioGPS gene expression data to be expressed in K562

Isotype:
Ig
Application Info:
WB: 1:1000
IF: 1:10~50
Additional Information:
Precautions: RARB Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
:::
Function: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function
:::
Cellular Location: Isoform Beta-1: Nucleus. Isoform Beta-4: Cytoplasm.

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