Product Number |
OAAB13645 |
Product Page |
www.avivasysbio.com/rarb-antibody-center-region-oaab13645.html |
Name |
RARB Antibody - middle region (OAAB13645) |
Molecular Weight |
50489 Da |
Isotype |
Ig |
NCBI Gene Id |
5915 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
Alias Symbols |
HAP, RRB2, NR1B2, MCOPS12, RARbeta1 |
Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Description of Target |
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for OAAB13645 |
Additional Information |
Precautions: RARB Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Additional Information |
Function: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function |
Application Info |
WB: 1:1000 IF: 1:10~50 |
Immunogen |
This RARB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-195 amino acids from the Central region of human RARB. |
Additional Information |
Cellular Location: Isoform Beta-1: Nucleus. Isoform Beta-4: Cytoplasm. |
Uniprot ID |
P10826 |
Protein Name |
Retinoic acid receptor beta |
Sample Type Confirmation |
RARB is supported by BioGPS gene expression data to be expressed in K562 |
Protein Accession # |
NP_000956.2 |
Gene Symbol |
RARB |
Predicted Species Reactivity |
Human, Mouse |
Application |
IF, WB |
Predicted Homology Based on Immunogen Sequence |
Human; Mouse |
Image 1 | Hela cell
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| Image 2 | K562 cell
| RARB Antibody (Center) (Cat. #OAAB13645) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the RARB antibody detected the RARB protein (arrow). |
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