MAP2K7 Antibody - N-terminal region (ARP81182_P050)

Catalog No: ARP81182_P050

Host: Rabbit
Target Name: MAP2K7
Sample Tissue: Human COLO205 Whole Cell lysates
Antibody Dilution: 1ug/ml

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAP2K7
• Purification: Affinity purified
• Peptide Sequence: Synthetic peptide located within the following region: LNLDISPQRPRPTLQLPLANDGGSRSPSSESSPQHPTPPARPRHMLGLPS
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-MAP2K7 (ARP81182_P050) antibody is Catalog # AAP81182

Target Info

• Gene Symbol: MAP2K7
• Gene Full Name: mitogen-activated protein kinase kinase 7
• Alias Symbols: MEK, MKK7, JNKK2, MEK 7, MAPKK7, PRKMK7, SAPKK4, SAPKK-4
• NCBI Gene Id: 5609
• Protein Name: dual specificity mitogen-activated protein kinase kinase 7
• Description of Target: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants.
• Uniprot ID: O14733-2
• Protein Accession #: NP_660186.1
• Nucleotide Accession #: NM_001297555.1
• Protein Size (# AA): 462
• Molecular Weight: 50 kDa