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MAP2K7 Antibody (Phospho-Ser271) (OAAF05547)

100 ug
$379.00
In Stock
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Conjugation Options

OAAF05547-FITC Conjugated

OAAF05547-HRP Conjugated

OAAF05547-Biotin Conjugated

Gene Symbol:
MAP2K7
NCBI Gene Id:
5609
Swissprot Id:
O14733
Alias Symbols:
c-Jun N-terminal kinase kinase 2, Dual specificity mitogen-activated protein kinase kinase 7, JNK activating kinase 2, JNK kinase 2, JNKK 2, JNKK2, kinase MKK7, MAP kinase kinase 7, MAP2K7, MAPK/ERK kinase 7, MAPKK 7, MP2K7, PRKMK7
Replacement Item:
This antibody may replace item sc-136337 from Santa Cruz Biotechnology.
Molecular Weight:
47 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation.
Application:
WB, IHC, ELISA
Immunogen:
The antiserum was produced against synthesized phospho-peptide derived from the Internal region of human MAP2K7 around the phosphorylation site of S271
Predicted Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid PBS (without Mg2+ and Ca2+) (pH 7.4), 150mM NaCl, 0.02% sodium azide and 50% glycerol
Reconstitution and Storage:
Store at -20C/1 year
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for OAAF05547
Specificity:
MAP2K7 (Phospho-Ser271) Antibody detects endogenous levels of MAP2K7 only when phosphorylated at S271
Isotype:
IgG
Application Info:
WB: 1:500~1000
IHC: 1:50~100
ELISA: 1:10000
Additional Information:
Modification Sites: Human: S271, Mouse: S287, Rat: S271
Publications:

Hepatocyte TRAF3 promotes liver steatosis and systemic insulin resistance through targeting TAK1-dependent signalling. Nat Commun. 7, 10592 (2016). WB, IHC, ELISA, Human, Mouse, Rat 26882989

Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates. Nat. Med. 23, 439-449 (2017). WB, IHC, ELISA, Human, Mouse, Rat 28218919

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