Size:100 ug
$299.00
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SKU
OAAF05547
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Conjugation Options

OAAF05547-FITC Conjugated

OAAF05547-HRP Conjugated

OAAF05547-Biotin Conjugated

MAP2K7 Antibody (Phospho-Ser271) (OAAF05547)

Catalog#: OAAF05547
Domestic: within 1 week delivery International: 1 week
More Information
Predicted Species Reactivity Human, Mouse, Rat
Product Format LiquidPBS (without Mg2+ and Ca2+) (pH 7.4), 150mM NaCl, 0.02% sodium azide and 50% glycerol
Clonality Polyclonal
Isotype IgG
Host Rabbit
Application WB, IHC
Additional Information Modification Sites: Human: S271, Mouse: S287, Rat: S271
Reconstitution and Storage Store at -20C/1 year
Replacement Item This antibody may replace item sc-136337 from Santa Cruz Biotechnology.
Immunogen The antiserum was produced against synthesized phospho-peptide derived from the Internal region of human MAP2K7 around the phosphorylation site of S271. Loc: 236-285aa
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phospho peptide.
Concentration 1 mg/ml
Datasheets/Manuals Printable datasheet for OAAF05547
Target Post-Translational Modification Phospho
Specificity MAP2K7 (Phospho-Ser271) Antibody detects endogenous levels of MAP2K7 only when phosphorylated at S271
Application Info WB: 1:500~1000
IHC: 1:50~100
ELISA: 1:20000
Publications

Hepatocyte TRAF3 promotes liver steatosis and systemic insulin resistance through targeting TAK1-dependent signalling. Nat Commun. 7, 10592 (2016). WB, IHC, ELISA, Human, Mouse, Rat26882989

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Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates. Nat. Med. 23, 439-449 (2017). WB, IHC, ELISA, Human, Mouse, Rat28218919

Gene Symbol MAP2K7
Alias Symbols c-Jun N-terminal kinase kinase 2, Dual specificity mitogen-activated protein kinase kinase 7, JNK activating kinase 2, JNK kinase 2, JNKK 2, JNKK2, kinase MKK7, MAP kinase kinase 7, MAP2K7, MAPK/ERK kinase 7, MAPKK 7, MP2K7, PRKMK7
NCBI Gene Id 5609
Swissprot Id O14733
Molecular Weight 47 kDa
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