Size:100 ul
Special Price $229.00 Regular Price $289.00
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ARP54688_P050
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Conjugation Options

ARP54688_P050-FITC Conjugated

ARP54688_P050-HRP Conjugated

ARP54688_P050-Biotin Conjugated

More Information
Tested Species Reactivity Human, Mouse
Predicted Species Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application IHC, WB
Additional Information IHC Information: Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-155994 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human LGALS3
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Cow: 93%; Dog: 93%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 92%; Rat: 93%
Complete computational species homology data Anti-LGALS3 (ARP54688_P050)
Peptide Sequence Synthetic peptide located within the following region: GASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPG
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-LGALS3 (ARP54688_P050) antibody is Catalog # AAP54688 (Previous Catalog # AAPP31479)
Datasheets/Manuals Printable datasheet for anti-LGALS3 (ARP54688_P050) antibody
Sample Type Confirmation

LGALS3 is supported by BioGPS gene expression data to be expressed in MCF7

Target Reference Bartolazzi,A., (2008) Lancet Oncol. 9 (6), 543-549
Publications

Guha, P. et al. Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, -alpha9 nicotinic acetylcholine receptor and STAT3. Breast Cancer Res. Treat. 145, 5-22 (2014). IHC, WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat 24668500

Gene Symbol LGALS3
Official Gene Full Name galectin 3
Alias Symbols L31, GAL3, MAC2, CBP35, GALBP, GALIG, LGALS2
NCBI Gene Id 3958
Protein Name galectin-3
Description of Target This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.
Swissprot Id P17931
Protein Accession # NP_002297
Nucleotide Accession # NM_002306
Protein Size (# AA) 250
Molecular Weight 26kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express LGALS3.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express LGALS3.
Protein Interactions PRR13; SS18L1; PPIG; LGALS3; GOLGA2; MAP1LC3A; SQSTM1; RAB7A; LAMP1; EGFR; CFTR; PAXIP1; BARD1; AGPS; IGBP1; GTF2I; CLNS1A; APP; SLC25A5; ACTA1; MYOC; LGALS3BP; CYHR1; GEMIN4; SUFU; CUBN; CSNK1A1; LIM2; FCGR2A; ELN; MMP2; CSNK2A2; CSNK2A1; C1GALT1C1; LGAL
  1. What is the species homology for "LGALS3 Antibody - N-terminal region (ARP54688_P050)"?

    The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat".

  2. How long will it take to receive "LGALS3 Antibody - N-terminal region (ARP54688_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "LGALS3 Antibody - N-terminal region (ARP54688_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "LGALS3 Antibody - N-terminal region (ARP54688_P050)"?

    This target may also be called "L31, GAL3, MAC2, CBP35, GALBP, GALIG, LGALS2" in publications.

  5. What is the shipping cost for "LGALS3 Antibody - N-terminal region (ARP54688_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "LGALS3 Antibody - N-terminal region (ARP54688_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "LGALS3 Antibody - N-terminal region (ARP54688_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "26kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "LGALS3 Antibody - N-terminal region (ARP54688_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "LGALS3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "LGALS3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "LGALS3"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "LGALS3"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "LGALS3"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "LGALS3"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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