KLK3 Antibody (OABF00883)

Catalog No: OABF00883

Size:100ul

Formalin-fixed and paraffin embedded human prostate labeled with Anti-KLK3 Polyclonal Antibody, Unconjugated (OABF00883) at 1:200 followed by conjugation to the secondary antibody Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37C and DAPI staining

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Conjugation: Unconjugated
• Application: WB, IHC-P
• Additional Information: Subcellular location: Secreted
• Reconstitution and Storage: Store at -20C for 12 months.
• Immunogen: KLH conjugated synthetic peptide derived from human KLK3
• Purification: Purified by Protein A.
• Concentration: 1ug/ul
• Application Info: WB: 1:100 - 1000
  IHC-P: : 1:100 - 500

Target Info

• Gene Symbol: KLK3
• Gene Full Name: kallikrein-related peptidase 3
• Alias Symbols: APS, PSA, hK3, KLK2A1
• NCBI Gene Id: 354
• Description of Target: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
• Uniprot ID: P07288