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KLK3 antibody - middle region (ARP41879_P050)

100 ul
$289.00
In Stock
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Conjugation Options

ARP41879_P050-FITC Conjugated

ARP41879_P050-HRP Conjugated

ARP41879_P050-Biotin Conjugated

Gene Symbol:
KLK3
NCBI Gene Id:
354
Official Gene Full Name:
Kallikrein-related peptidase 3
Protein Name:
Prostate-specific antigen
Swissprot Id:
P07288
Protein Accession #:
NP_001639
Nucleotide Accession #:
NM_001648
Alias Symbols:
APS, KLK2A1, PSA, hK3
Replacement Item:
This antibody may replace item sc-116410 from Santa Cruz Biotechnology.
Description of Target:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.
Protein Size (# AA):
261
Molecular Weight:
26kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express KLK3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express KLK3.
Tested Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Dog: 77%; Human: 100%; Mouse: 86%; Rat: 86%
Complete computational species homology data:
Anti-KLK3 (ARP41879_P050)
Peptide Sequence:
Synthetic peptide located within the following region: LRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSI
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
ALB; PZP; SERPINA5; SERPINA1; SEMG2; SEMG1; PLG; PTHLH; IGFBP3; FN1; EPOR; SLPI; SERPINA3; A2M; POLR2A; AR; KAT5; RUVBL1; CTNNB1;
Blocking Peptide:
For anti-KLK3 (ARP41879_P050) antibody is Catalog # AAP41879
Datasheets/Manuals:
Printable datasheet for anti-KLK3 (ARP41879_P050) antibody
Publications:

Alzghoul, S; Hailat, M; Zivanovic, S; Que, L; Shah, GV; Measurement of serum prostate cancer markers using a nanopore thin film based optofluidic chip. 77, 491-8 (2016). WB, Dog, Human, Mouse, Rat 26457734

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