INHBA Recombinant Protein (Human) (OPCA03886)

Catalog No: OPCA03886

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Liquid or Lyophilized powder
• Additional Information: Species Specificity Detail: Homo sapiens (Human)
• Reconstitution and Storage: -20°C or -80°C
• Formulation: Tris-base, 50% glycerol
• Purity: Greater than 90% as determined by SDS-PAGE.
• Peptide Sequence: GLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
• Protein Sequence: GLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
• Storage Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Source: E.coli
• Protein Range: 311-426 aa
• Tag: N-terminal 6xHis-SUMO-tagged
• Reference: Germline mutations of inhibins in early-onset ovarian epithelial tumors.Tournier I., Marlin R., Walton K., Charbonnier F., Coutant S., Thery J.C., Charbonnier C., Spurrell C., Vezain M., Ippolito L., Bougeard G., Roman H., Tinat J., Sabourin J.C., Stoppa-Lyonnet D., Caron O., Bressac-de Paillerets B., Vaur D. , King M.C., Harrison C., Frebourg T.Hum. Mutat. 35:294-297(2014)

Target Info

• Gene Symbol: INHBA
• Gene Full Name: inhibin subunit beta A
• Alias Symbols: activin beta-A chain;EDF;erythroid differentiation factor;erythroid differentiation protein;follicle-stimulating hormone-releasing protein;FRP;FSH-releasing protein;inhibin beta A chain;inhibin beta A subunit;inhibin, beta A (activin A, activin AB alpha polypeptide);Inhibin, beta-1.
• NCBI Gene Id: 3624
• Protein Name: Inhibin beta A chain
• Description of Target: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
• Uniprot ID: P08476
• Protein Accession #: NP_002183
• Nucleotide Accession #: NM_002192
• Protein Size (# AA): Recombinant
• Molecular Weight: 29 kDa