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Goat Anti-PTPN6 / SHP1 (internal region) Antibody (OAEB01207)

100 ug
$349.00
In Stock
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Gene Symbol:
PTPN6
NCBI Gene Id:
5777
Protein Name:
Protein tyrosine phosphatase, non-receptor type 6 EMBL AAP36054.1
Swissprot Id:
Q53XS4
Protein Accession #:
NP_536858.1
Alias Symbols:
PTPN6, SHP1, protein tyrosine phosphatase, non-receptor type 6, HCP, HCPH, HPTP1C, PTP-1C, SH-PTP1, SHP-1, SHP-1L, 70 kda SHP-1L protein, hematopoietic cell phosphatase, hematopoietic cell protein-tyrosine phosphatase, protein-tyrosine phosph
Replacement Item:
This antibody may replace item sc-176633 from Santa Cruz Biotechnology.
Host:
Goat
Clonality:
Polyclonal
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express PTPN6.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express PTPN6.
Immunogen:
This antibody is expected to recognise both reported isoforms (NP_536858.1and NP_002822.2).
Please note this antibody was designed using the mouse sequence, which differs by 1 amino acid from the human sequence.
Predicted Species Reactivity:
Dog, Guinea Pig, Horse, Human, Mouse, Rat
Predicted Homology Based on Immunogen Sequence:
Dog: 91%; Guinea Pig: 91%; Horse: 91%; Human: 91%; Mouse: 100%; Rat: 100%
Complete computational species homology data:
PTPN6 Antibody (OAEB01207)
Peptide Sequence:
C-KASRTSSKHKEE
Product Format:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Reconstitution and Storage:
Aliquot and store at -20C. Minimize freezing and thawing.
Datasheets/Manuals:
Printable datasheet for anti-PTPN6 antibody - OAEB01207
Purity:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Application Info:
Peptide ELISA: antibody detection limit dilution 1:128000.
Western Blot: Approx 60-70kDa band observed in Human Bone Marrow and Liver lysates (calculated MW of 67.6kDa according to NP_536858.1and NP_002822.2). Recommended concentration: 0.1-0.3ug/ml.
Target Reference:
* Dubois MJ, Bergeron S, Kim HJ, Dombrowski L, Perreault M, Fournes B, Faure R, Olivier M, Beauchemin N, Shulman GI, Siminovitch KA, Kim JK, Marette A.; The SHP-1 protein tyrosine phosphatase negatively modulates glucose homeostasis.; Nat Med. 2006 May;12(5):549-56. Epub 2006 Apr 16.; Pubmed 16617349

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