FOXO1A Antibody - N-terminal region (ARP38094_T100)

Catalog No: ARP38094_T100

WB Suggested Anti-FOXO1A Antibody Titration: 2.5ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Yeast
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FOXO1A
• Purification: Protein A purified
• Predicted Homology Based on Immunogen Sequence: Cow: 92%; Dog: 92%; Human: 100%; Mouse: 85%; Pig: 92%; Rat: 85%; Yeast: 85%
• Peptide Sequence: Synthetic peptide located within the following region: MAEAPQVVEIDPDFEPLPRPRSCTWPLPRPEFSQSNSATSSPAPSGSAAA
• Concentration: 1.0 mg/ml
• Blocking Peptide: For anti-FOXO1 (ARP38094_T100) antibody is Catalog # AAP38094 (Previous Catalog # AAPP20268)
• Reference: Okamoto,H., et al., (2006) J. Clin. Invest. 116 (3), 775-782
• Publications:

  Ambient temperature influences aging in an annual fish (Nothobranchius rachovii). Aging Cell. 8, 726-37 (2009). 19780720

  Hsu, C.-Y. & Hu, T.-H. Energy-regulated molecules maintain young status in the trophocytes and fat cells of old queen honeybees. Biogerontology 15, 389-400 (2014). 24973265

  Late-onset temperature reduction can retard the aging process in aged fish via a combined action of an anti-oxidant system and the insulin/insulin-like growth factor 1 signaling pathway. Rejuvenation Res. 17, 507-17 (2014). 25298234

• Description:
  View product citations for FOXO1A Antibody - N-terminal region (ARP38094_T100) on CiteAb

Target Info

• Gene Symbol: FOXO1
• Gene Full Name: Forkhead box O1
• Alias Symbols: FKH1, FKHR, FOXO1A
• NCBI Gene Id: 2308
• Protein Name: Forkhead box protein O1
• Description of Target: FOXO1A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of FOXO1A has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of FOXO1A gene with PAX3 has been associated with alveolar rhabdomyosarcoma.
• Uniprot ID: Q12778
• Protein Accession #: NP_002006
• Nucleotide Accession #: NM_002015
• Protein Size (# AA): 655
• Molecular Weight: 70kDa
• Protein Interactions: EP300; AKT1; MST1; SIRT1; FHL2; ATG7; IRF3; FSHR; ESR1; Ubc; TXNRD1; RARA; MDM2; NLK; SKP2; SIRT2; STUB1; CREBBP; PML; LRPPRC; HOXA11; HNF4A; PARP1; DYRK1A; THRB; CSNK1G1; YWHAG; GSK3B; SMAD3; PAK1; PPARG; YWHAZ; SMAD4; AR; G6PC; SRC; CEBPB; FOXG1; HOXA10