| Product Number |
ARP38094_T100 |
| Product Page |
www.avivasysbio.com/foxo1a-antibody-n-terminal-region-arp38094-t100.html |
| Name |
FOXO1A Antibody - N-terminal region (ARP38094_T100) |
| Protein Size (# AA) |
655 amino acids |
| Molecular Weight |
70kDa |
| NCBI Gene Id |
2308 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Forkhead box O1 |
| Description |
|
| Alias Symbols |
FKH1, FKHR, FOXO1A |
| Peptide Sequence |
Synthetic peptide located within the following region: MAEAPQVVEIDPDFEPLPRPRSCTWPLPRPEFSQSNSATSSPAPSGSAAA |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Okamoto,H., et al., (2006) J. Clin. Invest. 116 (3), 775-782 |
| Description of Target |
FOXO1A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of FOXO1A has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of FOXO1A gene with PAX3 has been associated with alveolar rhabdomyosarcoma. |
| Protein Interactions |
EP300; AKT1; MST1; SIRT1; FHL2; ATG7; IRF3; FSHR; ESR1; Ubc; TXNRD1; RARA; MDM2; NLK; SKP2; SIRT2; STUB1; CREBBP; PML; LRPPRC; HOXA11; HNF4A; PARP1; DYRK1A; THRB; CSNK1G1; YWHAG; GSK3B; SMAD3; PAK1; PPARG; YWHAZ; SMAD4; AR; G6PC; SRC; CEBPB; FOXG1; HOXA10 |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-FOXO1 (ARP38094_T100) antibody |
| Blocking Peptide |
For anti-FOXO1 (ARP38094_T100) antibody is Catalog # AAP38094 (Previous Catalog # AAPP20268) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human FOXO1A |
| Uniprot ID |
Q12778 |
| Protein Name |
Forkhead box protein O1 |
| Publications |
Ambient temperature influences aging in an annual fish (Nothobranchius rachovii). Aging Cell. 8, 726-37 (2009). 19780720
Hsu, C.-Y. & Hu, T.-H. Energy-regulated molecules maintain young status in the trophocytes and fat cells of old queen honeybees. Biogerontology 15, 389-400 (2014). 24973265
Late-onset temperature reduction can retard the aging process in aged fish via a combined action of an anti-oxidant system and the insulin/insulin-like growth factor 1 signaling pathway. Rejuvenation Res. 17, 507-17 (2014). 25298234 |
| Protein Accession # |
NP_002006 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_002015 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
FOXO1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Pig, Yeast |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 92%; Dog: 92%; Human: 100%; Mouse: 85%; Pig: 92%; Rat: 85%; Yeast: 85% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-FOXO1A Antibody Titration: 2.5ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate |
|
