FOLR1 Recombinant Protein (OPCD03286)

Catalog No: OPCD03286

FOLR1 Recombinant Protein (OPCD03286) using SDS-PAGE

FOLR1 Recombinant Protein (OPCD03286) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method).
  Subcellular Location: Membrane, Secreted
  Isoelectric Point: 8.2
  Residues: Arg25-Ser234
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 90%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: FOLR1
• Gene Full Name: folate receptor alpha
• Alias Symbols: adult folate-binding protein;FBP;folate binding protein;Folate receptor 1;folate receptor 1 (adult);folate receptor alpha;folate receptor, adult;FOLR;FRalpha;FR-alpha;KB cells FBP;NCFTD;ovarian tumor-associated antigen MOv18.
• NCBI Gene Id: 2348
• Protein Name: Folate receptor alpha
• Description of Target: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.
• Uniprot ID: P15328
• Protein Accession #: NP_000793.1
• Nucleotide Accession #: NM_000802.3
• Protein Size (# AA): Arg25~Ser234
• Molecular Weight: 28kDa