FGG Antibody (OASA02712)

Catalog No: OASA02712 (Formerly GWB-E98AAD)

Size:200UG

D-dimers are the principle degradation products of cross-linked fibrin, released into the bloodstream following the digestion of fibrin clots (thrombus) by the enzyme plasmin, and thus measurement of the level of D-dimer in plasma, can be used as an indication of thrombotic disorders. Conditions in which levels of D-dimer are elevated include deep vein thrombosis (DVT), venous thromboembolism (VTE), cardiovascular disease and disseminated intravascular coagulation (DIC), a possible acute condition arising from surgical operations, septic shock and liver disease.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. Phosphate buffered saline
• Clonality: Monoclonal
• Clone: DD6
• Isotype: IgG2a
• Host: Mouse
• Application: Enzyme-linked immunosorbent assay|Western blot
• Additional Information: Fusion Partners: Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cell line.
• Reconstitution and Storage: -20°C
• Immunogen: Homogenised fibrin clot.
• Purification: Protein A Purified
• Predicted Homology Based on Immunogen Sequence: Human
• Concentration: 1 mg/ml
• Specificity: Mouse anti Human D-Dimer antibody, clone DD6 recognizes human D-dimer and shows low cross-reactivity with fibrinogen (D-monomer).
• Reference: 1. Rowbotham, B.J. et al. (1987) Measurement of crosslinked fibrin derivatives--use in the diagnosis of venous thrombosis. Thromb. Haemost. 57: 59-61.
  2. Kruskal, J.B. et al. (1992) Elevated fibrin-related and fibrinogen-related antigens in patients with liver disease. Hepatology. 16: 920-923.
  

Target Info

• Gene Symbol: FGG
• Alias Symbols: FGG
• NCBI Gene Id: 2266
• Protein Name: Fibrinogen gamma chain
• Description of Target: MOUSE ANTI HUMAN D-DIMER
  
• Uniprot ID: P02679
• Protein Accession #: NP_000500.2
• Protein Size (# AA): 437