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Catalog No: OAAB17136
Size:400ul
Price: $450.00
SKU
OAAB17136
Availability: Domestic: within 1-2 week delivery | International: within 1-2 week delivery
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
  • Contact us for international orders.
Datasheets/ManualsPrintable datasheet for OAAB17136
Product Info
Predicted Species ReactivityHuman
Product FormatPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
ClonalityPolyclonal
IsotypeIg
HostRabbit
ApplicationWB, IHC
Additional InformationPrecautions: EphA7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
::Function: Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus. May also regulate brain development through a caspase(CASP3)-dependent proapoptotic activity. Forward signaling may result in activation of components of the ERK signaling pathway including MAP2K1, MAP2K2, MAPK1 AND MAPK3 which are phosphorylated upon activation of EPHA7
::Cellular Location: Cell membrane (Probable); Single-pass type I membrane protein (Probable)
Tissue Location: Widely expressed.
Reconstitution and StorageMaintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThis EphA7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 896-925 amino acids from the C-terminal region of human EphA7.
Predicted Homology Based on Immunogen SequenceHuman
ConcentrationApproximately 0.5mg/ml. Actual concentration varies with each lot.
Sample Type Confirmation

EPHA7 is strongly supported by BioGPS gene expression data to be expressed in HEK293

Application InfoWB: 1:1000
IHC-P: 1:50~100
Gene SymbolEPHA7
Alias SymbolsEHK3, EK11, EHK-3, HEK11
NCBI Gene Id2045
Protein NameEphrin type-A receptor 7
Description of TargetPurified Rabbit Polyclonal Antibody (Pab)
Uniprot IDQ15375
Protein Accession #NP_004431.1
Molecular Weight112097 Da
  1. What is the species homology for "EphA7 Antibody - C-terminal region (OAAB17136)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "EphA7 Antibody - C-terminal region (OAAB17136)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "EphA7 Antibody - C-terminal region (OAAB17136)" provided in?

    This item is provided in "Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "EphA7 Antibody - C-terminal region (OAAB17136)"?

    This target may also be called "EHK3, EK11, EHK-3, HEK11" in publications.

  5. What is the shipping cost for "EphA7 Antibody - C-terminal region (OAAB17136)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "EphA7 Antibody - C-terminal region (OAAB17136)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "EphA7 Antibody - C-terminal region (OAAB17136)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "112097 Da".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "EphA7 Antibody - C-terminal region (OAAB17136)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "EPHA7"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "EPHA7"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "EPHA7"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "EPHA7"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "EPHA7"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "EPHA7"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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