Size:100 ul
$289.00
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SKU
ARP61329_P050
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Conjugation Options

ARP61329_P050-FITC Conjugated

ARP61329_P050-HRP Conjugated

ARP61329_P050-Biotin Conjugated

EIF2B5 Antibody - N-terminal region (ARP61329_P050)

Catalog#: ARP61329_P050
Domestic: within 1-2 days delivery International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Cow, Dog, Horse, Human, Rat
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-111189 from Santa Cruz Biotechnology.
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Cow: 85%; Dog: 92%; Horse: 85%; Human: 100%; Rat: 85%
Complete computational species homology data Anti-EIF2B5 (ARP61329_P050)
Peptide Sequence Synthetic peptide located within the following region: GVVVSRANKRSGAGPGGSGGGGARGAEEEPPPPLQAVLVADSFDRRFFPI
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-EIF2B5 (ARP61329_P050) antibody is Catalog # AAP61329 (Previous Catalog # AAPP47461)
Datasheets/Manuals Printable datasheet for anti-EIF2B5 (ARP61329_P050) antibody
Subunit epsilon
Publications

Wortham, NC; Stewart, JD; Harris, S; Coldwell, MJ; Proud, CG; Stoichiometry of the eIF2B complex is maintained by mutual stabilization of subunits. 473, 571-80 (2016). WB, Cow, Dog, Horse, Human, Rat 26614765

Gene Symbol EIF2B5
Official Gene Full Name Eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
Alias Symbols CACH, CLE, EIF-2B, EIF2Bepsilon, LVWM
NCBI Gene Id 8893
Protein Name Translation initiation factor eIF-2B subunit epsilon
Description of Target This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
Swissprot Id Q13144
Protein Accession # NP_003898
Nucleotide Accession # NM_003907
Protein Size (# AA) 721
Molecular Weight 79kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express EIF2B5.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express EIF2B5.
Protein Interactions UBC; EGFR; EIF2B2; EIF2B3; EIF2B4; APP; CHMP2A; GSK3A; GSK3B; EIF2S2; CSNK1A1; CSNK2A2; CSNK2A1; EIF2B1;
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