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Catalog No: OAGA00965
Size:100 ul
Price: $369.00
SKU
OAGA00965
Availability: Domestic: within 1-2 week delivery | International: 1-2 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
  • Contact us for international orders.
Datasheets/ManualsPrintable datasheet for anti-DTX1 antibody - OAGA00965
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityMouse, Cow, Xenopus laevis
Product FormatLiquid. 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH 7). 0.01% Thimerosal was added as a preservative.
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ApplicationWB, ICC, IF, IHC-P
Reconstitution and StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
ImmunogenRecombinant protein encompassing a sequence within the center region of human Deltex1. The exact sequence is proprietary.
PurificationPurified by antigen-affinity chromatography.
Concentration1 mg/ml
Application InfoWB: 1:500-1:3000
ICC: 1:100-1:1000
IF: 1:100-1:1000
IHC-P: 1:100-1:1000
Optimal dilutions should be determined by the end user.
Publications

Glycogen synthase kinase 3β inhibition enhances Notch1 recycling. Mol Biol Cell. 29, 389-395 (2018). 29237816

PI5P4Kγ functions in DTX1-mediated Notch signaling. Proc Natl Acad Sci U S A. 115, E1983-E1990 (2018). 29440432

Description
Gene SymbolDTX1
Gene Full NameE3 ubiquitin-protein ligase DTX1
Alias SymbolshDx-1, RNF140
NCBI Gene Id1840
Protein NameE3 ubiquitin-protein ligase DTX1
Description of TargetStudies in Drosophila have identified this gene as encoding a positive regulator of the Notch-signaling pathway. The human gene encodes a protein of unknown function; however, it may play a role in basic helix-loop-helix transcription factor activity.
Uniprot IDQ86Y01
Protein Accession #NP_004407.2
Molecular Weight67 kDa
  1. What is the species homology for "DTX1 Antibody (OAGA00965)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Mouse, Cow, Xenopus laevis".

  2. How long will it take to receive "DTX1 Antibody (OAGA00965)"?

    This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".

  3. What buffer format is "DTX1 Antibody (OAGA00965)" provided in?

    This item is provided in "Liquid. 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH 7). 0.01% Thimerosal was added as a preservative. ".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "DTX1 Antibody (OAGA00965)"?

    This target may also be called "hDx-1, RNF140" in publications.

  5. What is the shipping cost for "DTX1 Antibody (OAGA00965)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "DTX1 Antibody (OAGA00965)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "DTX1 Antibody (OAGA00965)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "67 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "DTX1 Antibody (OAGA00965)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "DTX1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "DTX1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "DTX1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "DTX1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "DTX1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "DTX1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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