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DTX1 Antibody (OAGA00965)
| Datasheets/Manuals | Printable datasheet for anti-DTX1 antibody - OAGA00965 |
|---|
| Tested Species Reactivity | Human |
|---|---|
| Predicted Species Reactivity | Mouse, Cow, Xenopus laevis |
| Product Format | Liquid. 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH 7). 0.01% Thimerosal was added as a preservative. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Application | WB, ICC, IF, IHC-P |
| Reconstitution and Storage | Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles. |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Deltex1. The exact sequence is proprietary. |
| Purification | Purified by antigen-affinity chromatography. |
| Concentration | 1 mg/ml |
| Application Info | WB: 1:500-1:3000 ICC: 1:100-1:1000 IF: 1:100-1:1000 IHC-P: 1:100-1:1000 Optimal dilutions should be determined by the end user. |
| Publications | Glycogen synthase kinase 3β inhibition enhances Notch1 recycling. Mol Biol Cell. 29, 389-395 (2018). 29237816 PI5P4Kγ functions in DTX1-mediated Notch signaling. Proc Natl Acad Sci U S A. 115, E1983-E1990 (2018). 29440432 |
| Description |
| Gene Symbol | DTX1 |
|---|---|
| Gene Full Name | E3 ubiquitin-protein ligase DTX1 |
| Alias Symbols | hDx-1, RNF140 |
| NCBI Gene Id | 1840 |
| Protein Name | E3 ubiquitin-protein ligase DTX1 |
| Description of Target | Studies in Drosophila have identified this gene as encoding a positive regulator of the Notch-signaling pathway. The human gene encodes a protein of unknown function; however, it may play a role in basic helix-loop-helix transcription factor activity. |
| Uniprot ID | Q86Y01 |
| Protein Accession # | NP_004407.2 |
| Molecular Weight | 67 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "DTX1 Antibody (OAGA00965)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Mouse, Cow, Xenopus laevis".
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How long will it take to receive "DTX1 Antibody (OAGA00965)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "DTX1 Antibody (OAGA00965)" provided in?
This item is provided in "Liquid. 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH 7). 0.01% Thimerosal was added as a preservative. ".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "DTX1 Antibody (OAGA00965)"?
This target may also be called "hDx-1, RNF140" in publications.
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What is the shipping cost for "DTX1 Antibody (OAGA00965)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "DTX1 Antibody (OAGA00965)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "DTX1 Antibody (OAGA00965)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "67 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "DTX1 Antibody (OAGA00965)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "DTX1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "DTX1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "DTX1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "DTX1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "DTX1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "DTX1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
