DTX1 Antibody (OAGA00965)

Data Sheet
 
Product Number OAGA00965
Product Page www.avivasysbio.com/dtx1-antibody-oaga00965.html
Name DTX1 Antibody (OAGA00965)
Molecular Weight 67 kDa
Isotype IgG
NCBI Gene Id 1840
Host Rabbit
Clonality Polyclonal
Concentration 1 mg/ml
Gene Full Name E3 ubiquitin-protein ligase DTX1
Description
Alias Symbols hDx-1, RNF140
Product Format Liquid. 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH 7). 0.01% Thimerosal was added as a preservative.
Description of Target Studies in Drosophila have identified this gene as encoding a positive regulator of the Notch-signaling pathway. The human gene encodes a protein of unknown function; however, it may play a role in basic helix-loop-helix transcription factor activity.
Reconstitution and Storage Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-DTX1 antibody - OAGA00965
Application Info WB: 1:500-1:3000
ICC: 1:100-1:1000
IF: 1:100-1:1000
IHC-P: 1:100-1:1000
Optimal dilutions should be determined by the end user.
Immunogen Recombinant protein encompassing a sequence within the center region of human Deltex1. The exact sequence is proprietary.
Uniprot ID Q86Y01
Protein Name E3 ubiquitin-protein ligase DTX1
Publications

Glycogen synthase kinase 3β inhibition enhances Notch1 recycling. Mol Biol Cell. 29, 389-395 (2018). 29237816

PI5P4Kγ functions in DTX1-mediated Notch signaling. Proc Natl Acad Sci U S A. 115, E1983-E1990 (2018). 29440432

Protein Accession # NP_004407.2
Purification Purified by antigen-affinity chromatography.
Tested Species Reactivity Human
Gene Symbol DTX1
Predicted Species Reactivity Mouse, Cow, Xenopus laevis
Application WB, ICC, IF, IHC-P
Image 1
Hela
Sample (30 ug of whole cell lysate)
A: Hela
7.5% SDS PAGE
OAGA00965 diluted at 1:1000
Image 2
BT474 Xenograft
Immunohistochemical analysis of paraffin-embedded BT474 xenograft, using Deltex1(OAGA00965) antibody at 1:500 dilution.
Image 3
HeLa
Immunofluorescence analysis of methanol-fixed HeLa, using Deltex1(OAGA00965) antibody at 1:200 dilution.
 

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