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CHES1 Antibody - C-terminal region (ARP32841_T100)

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100 ul
$249.00
In Stock
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Conjugation Options

ARP32841_T100-FITC Conjugated

ARP32841_T100-HRP Conjugated

ARP32841_T100-Biotin Conjugated

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Gene Symbol:
FOXN3
Official Gene Full Name:
Forkhead box N3
NCBI Gene Id:
1112
Protein Name:
Forkhead box protein N3
Swissprot Id:
O00409
Protein Accession #:
NP_005188
Nucleotide Accession #:
NM_005197
Alias Symbols:
CHES1, PRO1635, C14orf116
Description of Target:
Checkpoint suppressor 1 is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway.
Protein Size (# AA):
468
Molecular Weight:
52kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Protein A purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express CHES1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express CHES1.
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human CHES1
Predicted Species Reactivity:
Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Tested Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Complete computational species homology data:
Anti-CHES1 (ARP32841_T100)
Peptide Sequence:
Synthetic peptide located within the following region: SGYASQHKKRQHFAKARKVPSDTLPLKKRRTEKPPESDDEEMKEAAGSLL
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
EXOSC8; SRPK2; ELAVL1; MEN1;
Blocking Peptide:
For anti-FOXN3 (ARP32841_T100) antibody is Catalog # AAP32841 (Previous Catalog # AAPP03861)
Datasheets/Manuals:
Printable datasheet for anti-FOXN3 (ARP32841_T100) antibody
Sample Type Confirmation:

FOXN3 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Target Reference:
Yu,Y., et al., (2001) Genome Res. 11 (8), 1392-1403
Publications:

Huot, G. et al. CHES1/FOXN3 regulates cell proliferation by repressing PIM2 and protein biosynthesis. Mol. Biol. Cell 25, 554-65 (2014). WB, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish 24403608

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